Medicinal chemistry of copper and vanadium bioactive compounds

New Developments in Medicinal Chemistry

Volumn , Issue , 2009, Pages 105-129

  Etcheverry, Susana B ^a   Williams, Patricia A M ^a  

^a FACULTAD DE CIENCIAS EXACTAS   (Argentina)

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EID: 84895301883     PISSN: None     EISSN: None     Source Type: Book    
DOI: None     Document Type: Chapter

References (169)

1. Allen, K.G.D.; Arthur, J.R.; Morrice, P.C.; Nicol, F.; Mills C.F. Proc. Soc. Exp. Biol. Med. 1988, 187, 38-43.
2. Auer, D. In: Free Radicals, Inflammation and Copper: Conference Proceedings, 11th Bain- Fallon Memorial Lecture, Australian Equine Veterinary Association, Coffs Harbour, Australia, 1989.
3. Baleuska, P.S.; Russanov, E.M.; Kassabova, T.A. Int. J. Biochem. 1981, 13, 489-493.
4. Baquial, J.G.L.; Sorenson, J.R.J. J. Inorg. Biochem. 1995, 60, 133-148.
5. Baran, E.J. In: Química Bioinorgánica; Mc.Graw-Hill; Madrid; 1994.
6. Barrio, D.A.; Cattáneo, E.R.; Apezteguía, M.C.; Etcheverry, S.B. Can. J. Physiol. Pharmacol. 2006, 84, 765-775.
7. Barrio, D.A.; Williams, P.A.M.; Cortizo, A.M.; Etcheverry, S.B. J. Biol. Inorg. Chem. 2003, 8, 459-468.
8. Barrio, D.A.; Etcheverry, S.B. Can. J. Physiol. Pharmacol. 2006, 84, 677-686.
9. Basson, M.D.; Emenaker, N.J.; Sanders, M.A. Cell. Physiol. Biochem. 2000, 10, 27-36.
10. Basson, M.D.; Turowski, G.; Emenaker, N.J. Exp. Cell Res. 1996, 255, 301-305.
11. Berthon, G. Agents Actions 1993, 39, 210-217.
12. Blázquez, G.; Galve-Roperh, I.; Guzman, M. FASEB J. 2000, 14, 2315-2322.
13. Brichard, S.M.; Henquin J.C. Trends Pharmacol. Sci. 1995, 16, 265-270.
14. Brumas, V.; Miche, H.; Fiallo, M. J. Inorg. Biochem. 2007, 101, 565-577.
15. Brunskill, A.P.J.; Thompson, H.W.; Lalancette, A. Acta Cryst. 1999, C55, 566-568.
16. Cam, M.C.; Rodrigues, B.; McNeill, J.H. Eur. J. Endocrinol. 1999, 141, 546-554.
17. Camakaris, J.; Voskoboinik, I.; Mercer, J.F. Biochem. Biophys. Res. Commun. 1999, 261, 225-232.
18. Cano, E.; Mahadevan, L.C. Trends Biochem. Sci. 1995, 20, 117-122.
19. Cappannelli, M.; Gaggelli, E.; Jezowska-Bojczuk, M.; Molteni, E.; Mucha, A.; Porciatti, E.; Valensin, D.; Valensin, G. J. Inorg. Biochem. 2007, 101, 1005-1012.
20. Carcelli, M.; Mazza, P.; Pelizzi, C.; Pelizzi, G.; Zani, F. J. lnorg. Biochem. 1995, 57, 43-62.
21. Chakraborty, T.; Chatterjee, A.; Rana, A.; Dhachinamoorthi, D.; Kumar A.; Chatterjee, M. Biochim. Biophys. Acta 2007, 1772, 48-59.
22. Cheta, D.; Orasanu, G.; Nicolaie, T.; Iordachescu, D.; Buligescu, S.; Constantin, C.; Hassanain, M.; Coman, A.; Enache, M.; Negru, R.; Tica, V.; Timofte, D.; Gutu, D.; Panaite, C. J. Cell. Mol. Med. 2003, 7, 447-454.
23. Cortizo, A.M.; Bruzzone, L.; Molinuevo, S.; Etcheverry, S.B. Toxicology 2000, 147, 89-99.
24. Cortizo, A.M.; Molinuevo, M.S.; Barrio, D.A.; Bruzzone, L. Int. J. Biochem. Cell Biol. 2006, 38, 1171-1180.
25. Crans, D.C. J. Inorg. Biochem. 2000, 80, 123-131.
26. Crans, D.C.; Smee, J.J.; Gaidamauskas, E.; Yang, L. Chem. Rev. 2004, 104, 849-902
27. Danen, E.H.J.; Yamada, K.M. J. Cell Phys. 2001, 189, 1-13.
28. Danks, D.M. Copper Deficiency in Humans. In: "Biological Roles of Copper." CIBA Foundation Symposium-79. Exerpta Medica, Amsterdam, 1980. p. 209.
29. De Alvare, L.R.; Goda, K.; Kimura, T. Biochem. Biophys. Res. Commun. 1976, 69, 687-694.
30. Díez, J. Clin. Therapeut. 2006, 28, 832-848.
31. DiSilvestro, R.A.; Marten J.T. J. Nutrition 1990, 120, 1223-1227.
32. Djordjevic, C. Met. íons. Biol. Syst. 1995, 31, 595-616.
33. Djordjevic, C.; Craig, S.A.; Sinn, E. Inorg. Chem. 1985, 24, 1281-1283.
34. Dollwet, H.H.A.; Sorenson, J.R.J. Tr. Elem. in Med. 1985, 2, 80-87.
35. Domingo, J.L. Reprod. Toxicol. 1996, 10,175-182.
36. Ekblom, P.; Lonai, P.; Talts, J.F. Matrix Biol. 2003, 22, 35-47.
37. Etcheverry, S.B.; Crans, D.C.; Keramidas, A.D.; Cortizo. A.M. Arch. Biochem. Biophys. 1997, 338, 7-14.
38. Etcheverry, S.B.; Barrio, D.A.; Cortizo, A.M.; Williams. P.A.M. J. Inorg. Biochem. 2002, 88, 94-100.
39. Etcheverry S.B.; Ferrer, E.G.; Naso, L.; Barrio, D.A.; Lezama, L.; Rojo, T.; Williams, P.A.M. Bioorg. Med. Chem. 2007, 15, 6418-6424.
40. Etcheverry, S.B.; Barrio, D.A. Vanadium and bone. Relevance of vanadium compounds in bone cells In: Vanadium: The versatile element. Kustin, K.; Costa Pesoa, J. Crans, D.C. (Eds) American Chemical Society Series 974. Vol 15: 204-216, 2007
41. Etcheverry, S.B., Ferrer, E.G., Naso, L.; Rivadeneira, J.; Salinas, V.; Williams, P.A.M. J. Biol. Inorg. Chem., 2008, 13, 435-447.
42. Evangelou, A.; Karkabounas, S.; Kalpouzos, G.; Malamas, M.; Llasko, R.; Stefanou, D.; Vlahos, A.T.; Kabanos, T.A. Cancer Lett. 1997, 119, 221-225.
43. Evangelou A.M. Crit. Rev. Onc. Hemat. 2002, 42, 249-265.
44. Ferrer, E.G.; Salinas, M.V.; Correa, M.J.; Naso, L.; Barrio, D.A.; Etcheverry, S.B.; Lezama, L.; Rojo, T.; Williams, P.A.M. J. Biol. Inorg. Chem. 2006, 11, 791-801.
45. Ferrer, E.G.; López Tévez, L.L.; Baeza, N.; Correa, M.J.; Okulik, N.; Lezama, L.; Rojo, T.; Castellano, E.E.; Piro, O.E.; Williams. P.A.M. J. Inorg. Biochem. 2007, 101, 741-749.
46. Fong, T.; Vij, R.; Vijayan, A.; DiPersio, J.; Blinder, M. Haematologica 2007, 92,1429-1430.
47. Franceschi, R.T.; Iyer, B.S.; Cui Y. J. Bone Miner. Res. 1994, 9, 843-854.
48. Frieden, E. Clin. Physiol. Biochem. 1986, 4, 11-19.
49. Gacheru, S.N.; Trackman, P.C.; Shah, M.A.; O'Gara C.Y.; Spacciapoli, P.; Greenaway, F.T.; Kagan, H.M. J. Biol. Chem. 1990, 265, 19022-19027.
50. Ghosh, P.; D'Cruz, O.J.; Narla, R.K.; Uckun, F.M. Clin. Cancer Res. 2000, 6, 1536-1545.
51. Gubler, C.J.; Lahey, M.E.; Cartwright, G.E., Wintrobe, M.M. J. Clin. Invest. 1953, 32, 405- 414.
52. Gutteridge, J.M.C.; Wilkins, S. Biochim. Biophys. Acta 1983, 759, 38-41.
53. Halova-Lajoie, B.; Brumas, V.; Fiallo M.M.L.; Berthon, G. J. Inorg. Biochem. 2006, 100, 362-373
54. Harless, W.; Crowell, E.; Abraham J. Am. J. Hematol. 2006, 81, 546-549.
55. Harris, E.D. In: Trace Elements in Health; Ed. J. Rose, Butterworths. London, 1983.
56. Harrison, J.R.; Rillema, D.P.; Ham, J.H.; Sando, J.J. Cancer Res. 1986, 46, 5571-5575.
57. Harwood M.; Danielewska-Nikiel, B; Borzelleca, J.F.; Flamm; G.W.; Williams, G.M.; Lines, T.C. Food Chem. Toxicol. 2007, 45, 2179-2205
58. Henke, S.L. Expert Opin. Ther. Pat. 1999, 9, 169-180.
59. Heyliger, C.E.; Tahiliani, A.G.; McNeill, J.H. Science, 1985, 227, 1474-1477.
60. Inutsuka, S.; Araki, S. Cancer 1978, 42, 626-631.
61. Ituarte, E.A.; Halstead, L.R.; Iida-Klein, A.; Ituarte, H.G.; Hahn, T.J. Calcif. Tissue Int. 1989, 45, 27-33.
62. Jackson, G.E.; May, P.M.; Williams, D.R. J. Inorg. Nucl. Chem. 1978, 40, 1189-1194.
63. Jackson, G.E.; Mkhonta-Gama, L.; Voyé, A.; Kelly, M. J. Inorg. Biochem. 2000, 79, 147- 152.
64. Jumarie, C.; Malo, C. J. Cell. Physiol. 1991, 149, 24-33.
65. Klevay, L.M. Med. Hypothesis 1987, 24, 111-119.
66. Klevay, L.M.; Inman, L.; Johnson, L.K.; Lawler, M.; Mahalko, J.R.; Milne, D.B.; Lukaski, H.C.; Bolonchuk, W.; Sandstead, H.H. Metabolism 1984, 33, 1112-1118.
67. Korolkiewicz, Z.; Hac, E.; Gagalo, I.; Gorczyca, P.; Lodzinska, A. Agents Actions 1989, 26, 355-359.
68. Kovala-Demertzi, D.; Galani, A.; Demertzis, M.A.; Skoulika, S. J. Inorg. Biochem. 2004, 98, 358-364
69. Lewis, A. J. Agents Actions 1984, 15, 513-519.
70. Liasko, R.; Kabanos, T.A.; Karkabounas, S.; Malamas, M.; Tasiopoulos, A.J.; Stefanou, D.; Collery, P.; Evangelou, A. Anticancer Res 1998, 18, 3609-3613.
71. Marshall, C.J. Cell 1995, 80,179-185.
72. Mason, K.E., J. Nutrit. 1979, 109, 1979-2066.
73. May P.M.; Williams, D.R. Role of low molecular weight complexes in the control of rheumatoid arthritis. InMetal Ions in Biological Systems. (Ed. H. Sigel) Marcel Dekker, New York 1981, Vol. 12, 283-317.
74. McCauley, L.K.; Koh, A.J.; Beecher, C.A.; Cui, Y.; Decker, J.D.; Franceschi, R.T. J. Bone Miner. Res. 1995, 10, 1243-1255.
75. McCauley L.K.; Koh, A.J.; Beecher C.A.; Cui Y.; Rosol, T.J.; Franceschi, R.T. J. Cell Biochem. 1996, 61, 638-647.
76. McCord, J.M. Science (Washington, DC) 1974,185, 529-531.
77. McNeill, J.H.; Delgatty, H.; Batell, M.L Diabetes 1991, 40, 1448-1452.
78. McNeill, J.H.; Yuen, V.G.; Hoveyda, H.R.; Orvig, C. J. Med. Chem. 1992, 35,1489-1491.
79. Melchior, M.; Thompson, K.H.; Jong, J.M.; Rettig, S.J.; Shuter, E.; Yuen, V.G.; Zhou, Y.; McNeill, J.H.; Orvig, C. Inorg. Chem. 1999, 38, 2288-2293.
80. Miche, H.; Brumas, V.; Berthon, G. J. Inorg. Biochem. 1997, 68, 27-38.
81. Milanino, R.; Passarella, E.; Velo, G. P. Copper in the inflammatory process. In Advances in Inflammation Research. (Eds. G. Weissmann, B. Samuelsson, and R. Paoletti) Raven Press, New York 1979, Vol. 1, pp. 281-291.
82. Milanino, R.; Conforti, A.; Franco, L.; Marrella, M.; Velo, G.P. Agents Actions 1985, 16, 504-513.
83. Milanino, R.; Buchner, V. Rev. Environ. Health 2006, 21, 153-215.
84. Miller, A.L. Alt. Med Rev. 1996, 1, 103-111.
85. Moen, M.D.; Wagstaff, A.J. Drugs 2005, 65, 2657-2674.
86. Molinuevo, M.S.; Barrio, D.A.; Cortizo, A.M.; Etcheverry. S.B. Cancer Chemother Pharmacol 2004, 53, 163-172.
87. Nagano, T.; Toyoda, T.; Tanabe, H.; Nagato, T.; Tsuchida, T.; Kitamura, Kasai A.G. Int. Med., 2005, 44, 554-559.
88. Néve, J.; Fontaine, J.; Peretz, A.; Famayer, J.P. Agents Actions 1988, 25, 146-155.
89. Nielsen, F.H.; Uthus, E.O. The essentiality and metabolism of vanadium. In: Chasteen, N.D. (ed) Vanadium in Biological Systems. Kluwer, Dordrecht, The Netherlands, 1990, pp. 51-62.
90. Oberley, L.W.; Buettner, G.R. Cancer Res. 1979, 39, 1141-1149.
91. Omoto, A.; Kawahito, Y.; Prudovsky, I.; Tubouchi, Y.; Kimura, M.; Ishino, H.; Wada, M.; Yoshida, M.; Cono, M.; Yoshimura, R.; Yoshikawa, T.; Sano, H. Arthritis Res. Ther. 2005, 7, R1174-R1182.
92. Orvig, C.; Thompson, K.H.; Battell, M.; McNeill, J.H. Metal ions biol. Syst.1995, 31, 575-594.
93. Osinska-Królicka, I.; Podsiadly, H.; Bukietynska, K.; Zemanek-Zboch, M.; Nowak, D.; Suchoszek-Lukaniuk K.; Malicka-Blaszkiewicz, M. J. Inorg. Biochem. 98, 2004, 2087- 2098.
94. Pandey, S.K.; berge, J.F.; Bernier, M.; Srivastava, A.K. Biochemistry 1999, 38, 14667-14675.
95. Partidge, N.C.; Alcom, D.; Michelangeli, V.V.P.; Ryan, G.; Martin, T.J. Cancer Res. 1983, 45, 4308-4314.
96. Petrone, W.F.; English, D.K.; Wong, K.; McCord J.M. Proc. Natl. Acad.Sci. USA. 1980, 77, 1159-1163.
97. Pietta, P.J. J. Nat. Prod. 2000, 63, 1035-1042
98. Posner, B.I.; Faure, R.; Burgess, J.W.; Bevan, A.P.; Lachance, D.; Zhang-Sun, G.; Fantus, I.G.; Ng, J.B.; Hall, D.A.; Lum, B.S. J. Biol. Chem. 1994, 269, 4596-4604.
99. Poucheret, P.; Verma, S.; Grynpas, M.D.; McNeill, J.H. Mol. Cell. Biochem. 1998, 188, 73-80.
100. Quarles, L.D.; Hartle, J.E. 2nd; Siddhanti, S.R.; Guo, R.; Hinson, T.K. J. Bone Miner. Res. 1997, 12, 393-402.
101. Ray, S.; Ghosh, B.; Rana, A.; Chatterjee, M. Int. J. Cancer 2006, 120, 13-23.
102. Rehder, D. Inorg. Chem. Comun. 2003, 6, 604-617.
103. Reul, B.A.; Amin, S.S.; Buchet, J.P.; Ongemba, L.N.; Crans, D.C.; Brichard, S.M.; Br. J. Pharmacol. 1999, 126, 467-477.
104. Richards, A.B.; Krakowka, S.; Dexter, L.B.; Schmid, H.; Wolterbeek, A.P.M.; Waalkens- Berendsen, D.H.; Shigoyuki, A.; Kurimoto, M. Food Chem. Toxicol. 2002, 40, 871-898.
105. Robinson, M.J.; Cobb, M.H. Curr. Opin. Cell. Biol. 1997, 9, 180-186.
106. Rodríguez-Ciria, M.; Sanz, A.M.; Yunta, M.J.R.; Gómez-Contreras, F.; Navarro, P.; Sánchez- Moreno, M.; Boutaleb-Charki, S.; Osuna, A.; Castiñeiras, A.; Pardo, M.; Cano, C.; Campayo, L. Bioorg. Med. Chem. 2007, 15, 2081-2091.
107. Romero-Chapman, N.; Lee, J.; Tinker, D.; Uriu-Hare, J.Y.; Keen, C.L.; Rucker, R.R. Biochem. J. 1991, 275, 657-662.
108. Sakurai, H.A.; Tsuchiya, K.; Nukatsuka, M.; Sofue, M.; Kawada, J.; J. Endocrinol. 1990, 126, 451-459.
109. Sakurai H. Envir. Health Perspect. 1994, 3, 35-36.
110. Sakurai, H. Chem. Rec. 2002, 2, 237-248.
111. Sakurai, H.; Kojima, Y.; Yoshikawa, Y.; Kawabe, K.; Yasui, H. Coord. Chem. Rev. 2002, 226,187-198.
112. Sakurai, H. Clin. calcium 2005, 15, 49-57.
113. Salgado, A.J.; Coutinho, O.P.; Reis, R.L. Bioscience 2004, 4, 643-765.
114. Sambuy, Y.; De Angelis, I.; Ranaldi, G.; Scarino, M.L.; Stammati, A.; Zucco, F. Cell. Biol. Toxicol. 2005, 21, 1-26.
115. Samuni, A.; Chevion, M.; Czapski, G. J. Biol. Chem 1981, 256, 12632-12635.
116. Schwarzbauer, J.E.; Sechler J.L. Curr. Opin. Cell Biol. 1999, 11, 622-627.
117. Scior, T.; Guevara-Garcia, A.; Bernard, P.; Do, Q.; Domeyer, D.; Laufer, S. Mini Rev. Med. Chem. 2005, 5, 995-1008.
118. Senthil Kumar, R.; Sasikala, K.; Arunachalam S. J. Inorg. Biochem., 2008, 102, 234-241.
119. Shisheva, A.; Shechter, Y. FEBS Lett. 1992, 23, 93
120. Shukla, R.; Barve, V.; Pakhye, S.; Bhonde, R. Bioorg. Med. Chem. Lett. 2004, 14, 4961-4965.
121. Shukla, R.; Barve, V.; Pakhye, S.; Bhonde, R. Biometals 2006, 19, 685-693.
122. Shukla, R.; Pakhye, S.; Modak, M.; Ghaskadbi, S.S.; Bhonde, R. Rev. Diabet. Stud. 2007, 4, 33-43.
123. Sica, D.A.; Gehr, T.W.; Ghosh, S. Clin. Pharmacokinet. 2005, 44, 797-814.
124. Siddhanti, S.R.; Quarles, L.D. J. Cell. Biochem. 1994, 55, 310-320.
125. Sigel, H.; Sigel, A. (Eds.) Vanadium and its Role in Life. In: Metal Ions in Biological Systems, Marcel Dekker, New York, vol. 31, 1995.
126. Siyuan, Z.; Yen-Kim, W.; Choon-Nam, O.; Han-Ming, S. Curr. Med. Chem. 2005, 3, 239- 249.
127. Solomons, N.W. J. Am. Coll. Nutr. 1985, 4, 83-105.
128. Sorenson, J.R.J. In: H. Sigel (Ed.), Met. Ions Biol. Syst. 1976, 14, 77-124.
129. Sorenson, J.R.J. J. Med. Chem. 1976, 19, 135-148.
130. Sorenson, J.R.J. J. Pharm. Pharmac. 1977, 2, 450-452
131. Sorenson, J.R.J. Prog. Med. Chem. 1978, 15, 211-260.
132. Sorenson, J.R.J. Patent Application: US 75-563778 19750331, CAN 94:25225: Antiinflammatory and Anti-ulcer Compounds and Processes, 1980.
133. Sorenson, J.R.J. The anti-inflammatory activities of copper complexes. In Metal Ions in Biological Systems. (Ed. H. Sigel) Marcel Dekker, New York 1982. Vol. 14, pp. 77-124.
134. Sorenson, J.R.J. (Ed.) Inflammatory Diseases and Copper, The Humana Press, Clifton, NJ 1982, 289-301.
135. Sorenson, J.R.J.; Oberley, L.W.; Crouch, R.K.; Kensler, T.W.; Kishore, V.; Leuthauser, S.W.C.; Oberley T.D.; Pezeshk, A. Biol. Tr. Elem. Res. 1983, 5, 257-273.
136. Sorenson, J.R.J.; Kishore, V.; Pezeshk, A.; Oberley, J.W.; Leuthauser, S.W.C.; T. Oberley, D. Inorg. Chim. Acta 1984, 91, 285-294.
137. Sorenson, J.R.J.; Kishore, V. Tr. Elem. Med. 1984, 1, 93-102.
138. Sorenson, J.R.J. Med. Bio. 1985, 63, 40-43.
139. Sorenson, J.R.J. (ed.), Biology of Copper Complexes. Humana Press, Clifton, NJ. 1987.
140. Sorenson, J.R.J. In: Milanino, R.; Rainsford, K.D.; Velo, G.P. (Eds.), Copper and Zinc in Inflammation, Kluwer Academic Publishers, Dordrecht, 1989, p. 69.
141. Sorenson, J.R.J. Prog. Med. Chem. 1989, 26, 437-568.
142. Sottile. J.; Hocking, D.C. Mol. Biol. Cell 2002, 13, 3546-3559.
143. Steinkühler, C.; Mavelli, I.; Melino, G.; Rossi, L.; Weser, U.; Rotilio, G. Ann. N.Y. Acad. Sci. 1988, 551, 133-136.
144. Sudo, H.; Kodama, H.A.; Amagai, Y.; Yamamoto, S.; Kasai, S. J. Cell. Biol. 1983, 96, 191- 198.
145. Swarup, G.; Cohen, S.; Garbers, D.I. Biochem. Biophys. Res. Commun. 1982, 107, 1104- 1109.
146. Teller, I.C.; Beaulieu, J.F. Expert. Rev. Mol. Med. 2001, 28, 1-18.
147. Thomas, D.M.; Hards, D.K.; Rogers, S.D.; Ng, K.W.; Best, J.D. J. Bone Miner. Res. 1996a, 11, 1312-1320.
148. Thomas, D.M.; Maher, F.; Rogers, S.D.; Best J.D. Biochem Biophys. Res. Commun.1996b, 218, 789-793.
149. Thompson, K.H. BioFactors 1999, 10, 43-51.
150. Thompson, K.H.; Tsukada, Y.; Xu, Z.; Battell, M.; McNeill, J.H.; Orvig, C. Biol. Trace Elem. Res. 2002, 86, 31-44.
151. Tracey, A.S., Gresser, M.J. Proc. Natl. Acad. Sci. USA 1986, 83, 609-613.
152. Tripoli, E., La Guardia, M.; Giammanco, S.; Di Majo, D.; Giammanco, M Food Chem. 2007,104, 466-479.
153. Urquiola, C.; Gambino, D.; Cabrera, M.; Lavaggi, M.L.; Cerecetto, H.; González, M.; López de Cerain, A.; Monge, A.; Costa-Filho, A.J.; Torre, M.H. J. Inorg. Biochem. 2008, 102, 119-126.
154. Valent, A.; Melník, M.; Hudecova, D.; Dudova, B.; Kivekäs, R.; Sundberg, M.R. Inorg. Chim.Acta 2002, 340, 15-/20.
155. Varga, F.; Luegmayr, E.; Fratzl-Zelman, N.; Glantschnig, H.; Ellinger, A.; Prinz, D.; Rumpler, M.; Klaushofer, K. J. Endocrinol. 1999, 160, 57-65.
156. Viossat, B.; Daran, J.C.; Savouret, G.; Morgant, G.; Greenaway, F.T.; Dung, N.H.; Pham- Tran, V.A.; Sorenson, J.R.J. J. Inorg. Biochem. 2003, 96, 375-385 and references therein.
157. Wang, H.; Scott, R.E. Mol. Cell. Biochem. 1995,153, 59-67.
158. Wang, T.; Guo, Z. Curr. Med. Chem. 2006,13, 525-537.
159. Weder, J.E.; Dillon, C.T.; Hambley, T.V.; Kennedy, B.J.; Lay, P.A.; Biffin, J.R.; Regtop, H.L.; Davies, N.M. Coord. Chem. Rev. 2002, 232, 95-126.
160. Weser, U.; Richter, C.; Wendel, A.; Younes, M. Bioinorg. Chem. 1978, 8, 201-213.
161. Whyte, M.P. "Hypophosphatasia". In: Scriver CR et al. (Eds). The metabolic and molecular basis of inherited disease. 7 ed. New York. McGraw Hill, Chapter 207, 2002, CDRom
162. Williams, P.A.M.; Zinczuk, J.; Barrio, D.A.; Piro, O.E.; Nascimento, O.R.; Etcheverry, S.B. Bioorg. Med. Chem. 2008, 16, 4313-4322.
163. Willingham W.M.; Sorenson, J.R.J. Tr. Elem. Med. 1986, 3, 139-140.
164. Winyard, P.G.; Pall, H.; Lunec, J.; Blake, D. R. Biochem. J. 1987, 247, 245-246.
165. Wong, P.C.; Barnes, T.B.; Chiu, A.T.; Christ, D.D.; Duncia, J.V.; Herblin, W.F.; Timmermans, P.B.M.W.M. Cardiovasc. Drug Rev. 1991, 9, 317-339.
166. Xia, Z.; Dickens, M.; Raingeaud, J.; Davis, R.J.; Greenberg, M.E. Science 1995, 270, 1326- 1331.
167. Xiao, G.; Gopalakrishnan, R.; Jiang, D.; Reith, E.; Benson, M.D.; Franceschi, R.T. J. Bone Miner. Res. 2002, 17, 101-110.
168. Yasui, H.; Tamura, A.; Takino, T.; Sakurai, H. J. Inorg. Biochem. 2002, 91, 327-338.
169. Younes, M.; Weser, U. Biochem. Biophys. Res. Commun. 1977, 78, 1247-1253.