Evaluation of selective cannabinoid CB1 and CB2 receptor agonists in a mouse model of lipopolysaccharide-induced interstitial cystitis

European Journal of Pharmacology

Volumn 729, Issue 1, 2014, Pages 67-74

  Tambaro, Simone ^a,b   Casu, Maria Antonietta ^c   Mastinu, Andrea ^c   Lazzari, Paolo ^a,d,e  

^a Neuroscienze PharmaNess Scarl   (Italy)

^b UNIVERSITY OF KANSAS   (United States)

^c INSTITUTE OF TRANSLATIONAL PHARMACOLOGY   (Italy)

^d UNIVERSITY OF SASSARI   (Italy)

^e KemoTech Srl   (Italy)

Author keywords

Intestitial cystitis; Isolated bladder assay; JWH015; Leukocytes infiltration; Mast cells; Myeloperoxidase activity

Indexed keywords

2 METHYL 3 (1 NAPHTHOYL) 1 PROPYLINDOLE; 6 IODO 3 (4 METHOXYBENZOYL) 2 METHYL 1 (2 MORPHOLINOETHYL)INDOLE; ACETYLCHOLINE; ARACHIDONYL 2 CHLOROETHYLAMIDE; CANNABINOID 1 RECEPTOR; CANNABINOID 1 RECEPTOR AGONIST; CANNABINOID 2 RECEPTOR; CANNABINOID 2 RECEPTOR AGONIST; INTERLEUKIN 1ALPHA; INTERLEUKIN 1BETA; LIPOPOLYSACCHARIDE; MESSENGER RNA; MYELOPEROXIDASE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; ARACHIDONIC ACID DERIVATIVE; ARACHIDONYL-2-CHLOROETHYLAMIDE; CANNABINOID; INDOLE DERIVATIVE; JHW 015;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; BLADDER CONTRACTION; BLADDER DYSFUNCTION; BLADDER FUNCTION; CELL INFILTRATION; CONTROLLED STUDY; DOSE RESPONSE; ENZYME ACTIVITY; HISTOLOGY; INTERSTITIAL CYSTITIS; LEUKOCYTE; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; AGONISTS; ANIMAL; CHEMICALLY INDUCED; CYSTITIS, INTERSTITIAL; DISEASE MODEL; DRUG SCREENING; ORGAN CULTURE TECHNIQUE; PHYSIOLOGY; PROCEDURES; TOXICITY;

ANIMALS; ARACHIDONIC ACIDS; CANNABINOIDS; CYSTITIS, INTERSTITIAL; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG EVALUATION, PRECLINICAL; INDOLES; LIPOPOLYSACCHARIDES; MALE; MICE; ORGAN CULTURE TECHNIQUES; RECEPTOR, CANNABINOID, CB1; RECEPTOR, CANNABINOID, CB2;

EID: 84895156238     PISSN: 00142999     EISSN: 18790712     Source Type: Journal    
DOI: 10.1016/j.ejphar.2014.02.013     Document Type: Article

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