Comorbidity of eczema, rhinitis, and asthma in IgE-sensitised and non-IgE-sensitised children in MeDALL: A population-based cohort study

The Lancet Respiratory Medicine

Volumn 2, Issue 2, 2014, Pages 131-140

  Pinart, Mariona ^a,b,c,d   Benet, Marta ^a,c,d   Annesi Maesano, Isabella ^e,f   von Berg, Andrea ^g   Berdel, Dietrich ^g   Carlsen, Karin C L ^h   Carlsen, Kai Håkon ^h   Bindslev Jensen, Carsten ⁱ   Eller, Esben ⁱ   Fantini, Maria P ^j   Lenzi, Jacopo ^j   Gehring, Ulrike ^k   Heinrich, Joachim ^l   Hohmann, Cynthia ^m   Just, Jocelyne ^o   Keil, Thomas ^m,p   Kerkhof, Marjan ^r   Kogevinas, Manolis ^a,b,c,d,s   Koletzko, Sibylle ^t   Koppelman, Gerard H ^q   Kull, Inger ^u,v   Lau, Susanne ^m   Melén, Erik ^u,v   Momas, Isabelle ^n,w   Porta, Daniela ^x   Postma, Dirkje S ^r   Rancière, Fanny ^n,w   Smit, Henriette A ^y   Stein, Renato T ^z   Tischer, Christina G ^l   Torrent, Maties ^aa   Wickman, Magnus ^u,v   Wijga, Alet H ^ab   Bousquet, Jean ^ac,ad   Sunyer, Jordi ^a,b,c,d   Basagaña, Xavier ^a,c,d   Guerra, Stefano ^a,c,d,ae   Garcia Aymerich, Judith ^a,c,d   Antó, Josep M ^a,b,c,d   more..

^a CENTRE FOR RESEARCH IN ENVIRONMENTAL EPIDEMIOLOGY CREAL   (Spain)

^b HOSPITAL DEL MAR   (Spain)

^c CIBER EPIDEMIOLOGÍA Y SALUD PÚBLICA CIBERESP   (Spain)

^d UNIVERSITAT POMPEU FABRA   (Spain)

^e INSERM   (France)

^f SORBONNE UNIVERSITÉ   (France)

^g MARIEN HOSPITAL WESEL   (Germany)

^h OSLO UNIVERSITY HOSPITAL   (Norway)

ⁱ ODENSE UNIVERSITY HOSPITAL   (Denmark)

^j UNIVERSITY OF BOLOGNA   (Italy)

^k UTRECHT UNIVERSITY   (Netherlands)

^l INSTITUTE OF EPIDEMIOLOGY   (Germany)

^m CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

ⁿ AP HP   (France)

^o ARMAND TROUSSEAU HOSPITAL   (France)

^p UNIVERSITY OF WÜRZBURG   (Germany)

^q UNIVERSITY OF GRONINGEN   (Netherlands)

^r UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

^s NATIONAL SCHOOL OF PUBLIC HEALTH   (Greece)

^t LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

^u KAROLINSKA INSTITUTE   (Sweden)

^v SACHS CHILDREN S HOSPITAL   (Sweden)

^w Paris Municipal Department of Social Action Childhood and Health   (France)

^x DEPARTMENT OF EPIDEMIOLOGY   (Italy)

^y UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^z PONTIFICAL CATHOLIC UNIVERSITY OF RIO GRANDE DO SUL   (Brazil)

^aa University Medical Center Utrecht ^*  (Spain)

^ab NATIONAL INSTITUTE FOR PUBLIC HEALTH AND THE ENVIRONMENT   (Netherlands)

^ac WHO Collaborating Center for Rhinitis and Asthma   (France)

^ad HÔPITAL ARNAUD DE VILLENEUVE   (France)

^ae UNIVERSITY OF ARIZONA   (United States)

more..

Author keywords

[No Author keywords available]

Indexed keywords

ASTHMA; CHILD; CHILD, PRESCHOOL; COMORBIDITY; CROSS-SECTIONAL STUDIES; ECZEMA; EUROPE; FEMALE; FOLLOW-UP STUDIES; HUMANS; IMMUNOGLOBULIN E; IMMUNOLOGIC FACTORS; LINEAR MODELS; MALE; PREVALENCE; PROSPECTIVE STUDIES; QUESTIONNAIRES; RHINITIS; RISK;

EID: 84895074399     PISSN: 22132600     EISSN: None     Source Type: Journal    
DOI: 10.1016/S2213-2600(13)70277-7     Document Type: Article

References (53)

1. Barnett K, Mercer SW, Norbury M, Watt G, Wyke S, Guthrie B Epidemiology of multimorbidity and implications for health care, research, and medical education: a cross-sectional study. Lancet 2012, 380:37-43.
2. Valderas JM, Starfield B, Sibbald B, Salisbury C, Roland M Defining comorbidity: implications for understanding health and health services. Ann Fam Med 2009, 7:357-363.
3. Lee D-S, Park J, Kay KA, Christakis NA, Oltvai ZN, Barabási A-L The implications of human metabolic network topology for disease comorbidity. Proc Natl Acad Sci USA 2008, 105:9880-9885.
4. Eder W, Ege MJ, Von Mutius E The asthma epidemic. N Engl J Med 2006, 355:2226-2235.
5. Ballardini N, Kull I, Lind T, et al. Development and comorbidity of eczema, asthma and rhinitis to age 12: data from the BAMSE birth cohort. Allergy 2012, 67:537-544.
6. Strachan D, Sibbald B, Weiland S, et al. Worldwide variations in prevalence of symptoms of allergic rhinoconjunctivitis in children: the International Study of Asthma and Allergies in Childhood (ISAAC). Pediatr Allergy Immunol 1997, 8:161-176.
7. Hopper JL, Bui QM, Erbas B, et al. Does eczema in infancy cause hay fever, asthma, or both in childhood? Insights from a novel regression model of sibling data. J Allergy Clin Immunol 2012, 130:1117. 22.e1.
8. Spergel JM, Paller AS Atopic dermatitis and the atopic march. J Allergy Clin Immunol 2003, 112:S118-S127.
9. Kjaer HF, Eller E, Høst A, Andersen KE, Bindslev-Jensen C The prevalence of allergic diseases in an unselected group of 6-year-old children. The DARC birth cohort study. Pediatr Allergy Immunol 2008, 19:737-745.
10. Westman M, Stjärne P, Asarnoj A, et al. Natural course and comorbidities of allergic and nonallergic rhinitis in children. J Allergy Clin Immunol 2012, 129:403-408.
11. Chawes BLK, Bønnelykke K, Kreiner-Møller E, Bisgaard H Children with allergic and nonallergic rhinitis have a similar risk of asthma. J Allergy Clin Immunol 2010, 126. 567-73.e1-8.
12. Bousquet J, Anto J, Auffray C, et al. MeDALL (Mechanisms of the Development of ALLergy): an integrated approach from phenotypes to systems medicine. Allergy 2011, 66:596-604.
13. Antó JM, Pinart M, Akdis M, et al. Understanding the complexity of IgE-related phenotypes from childhood to young adulthood: a Mechanisms of the Development of Allergy (MeDALL) seminar. J Allergy Clin Immunol 2012, 129:943. 54.e4.
14. Sunyer J, Torrent M, Garcia-Esteban R, et al. Early exposure to dichlorodiphenyldichloroethylene, breastfeeding and asthma at age six. Clin Exp Allergy 2006, 36:1236-1241.
15. Lødrup Carlsen KC The environment and childhood asthma (ECA) study in Oslo: ECA-1 and ECA-2. Pediatr Allergy Immunol 2002, 13(suppl 15):29-31.
16. Berg AV, Krämer U, Link E, et al. Impact of early feeding on childhood eczema: development after nutritional intervention compared with the natural course-the GINIplus study up to the age of 6 years. Clin Exp Allergy 2010, 40:627-636.
17. Zutavern A, Brockow I, Schaaf B, et al. Timing of solid food introduction in relation to eczema, asthma, allergic rhinitis, and food and inhalant sensitization at the age of 6 years: results from the prospective birth cohort study LISA. Pediatrics 2008, 121:e44-e52.
18. Bergmann RL, Bergmann KE, Lau-Schadensdorf S, et al. Atopic diseases in infancy. The German multicenter atopy study (MAS-90). Pediatr Allergy Immunol 1994, 5:19-25.
19. Wijga AH, Kerkhof M, Gehring U, et al. Cohort profile: the Prevention and Incidence of Asthma and Mite Allergy (PIAMA) birth cohort. Int J Epidemiol 2013, published online Jan 11. 10.1093/ije/dys231.
20. Drouillet P, Forhan A, De Lauzon-Guillain B, et al. Maternal fatty acid intake and fetal growth: evidence for an association in overweight women. The 'EDEN mother-child' cohort (study of pre- and early postnatal determinants of the child's development and health). Br J Nutr 2009, 101:583-591.
21. Clarisse B, Nikasinovic L, Poinsard R, Just J, Momas I The Paris prospective birth cohort study: which design and who participates?. Eur J Epidemiol 2007, 22:203-210.
22. Porta D, Fantini MP Prospective cohort studies of newborns in Italy to evaluate the role of environmental and genetic characteristics on common childhood disorders. Ital J Pediatr 2006, 32:350-357. on behalf of the GASPII and Co.N.ER Study Groups.
23. Wickman M, Kull I, Pershagen G, Nordvall SL The BAMSE project: presentation of a prospective longitudinal birth cohort study. Pediatr Allergy Immunol 2002, 13(suppl 15):11-13.
24. Ramón R, Ballester F, Rebagliato M, et al. The Environment and Childhood Research Network ('INMA' network): study protocol. Rev Esp Salud Publica 2005, 79:203-220. (in Spanish).
25. Barnetson RSC, Rogers M Childhood atopic eczema. BMJ 2002, 324:1376-1379.
26. Jarvis D, Newson R, Lotvall J, et al. Asthma in adults and its association with chronic rhinosinusitis: the GA2LEN survey in Europe. Allergy 2012, 67:91-98.
27. Asher MI, Keil U, Anderson HR, et al. International Study of Asthma and Allergies in Childhood (ISAAC): rationale and methods. Eur Respir J 1995, 8:483-491.
28. Pinart M, Maier D, Gimeno-Santos E, et al. Systematic review protocol to define classical IgE-associated diseases from birth to adolescence: the MeDALL study. WebmedCentral ALLERGY; 3: WMC003408.
29. Marrugat J, Vila J, Pavesi M, Sanz F Estimation of the sample size in clinical and epidemiological investigations. Med Clin (Barc) 1998, 111:267-276. (in Spanish).
30. Hosmer DW, Lemeshow S Applied logistic regression 2000, Wiley, New York.
31. Van Buuren S, Boshuizen HC, Knook DL Multiple imputation of missing blood pressure covariates in survival analysis. Stat Med 1999, 18:681-694.
32. Wang XS, Shek LP, Ma S, Soh SE, Lee BW, Goh DYT Time trends of co-existing atopic conditions in Singapore school children: prevalence and related factors. Pediatr Allergy Immunol 2010, 21:e137-e141.
33. Pekkanen J, Sunyer J, Anto JM, Burney P Operational definitions of asthma in studies on its aetiology. Eur Respir J 2005, 26:28-35.
34. Brand PLP, Baraldi E, Bisgaard H, et al. Definition, assessment and treatment of wheezing disorders in preschool children: an evidence-based approach. Eur Respir J 2008, 32:1096-1110.
35. Rothman KJ, Greenland S Modern epidemiology 1998, Lippincott-Raven, Philadelphia. 2nd edn.
36. Rochat MK, Illi S, Ege MJ, et al. Allergic rhinitis as a predictor for wheezing onset in school-aged children. J Allergy Clin Immunol 2010, 126:1170. 75.e2.
37. Kusel MMH, Holt PG, De Klerk N, Sly PD Support for 2 variants of eczema. J Allergy Clin Immunol 2005, 116:1067-1072.
38. Bertelsen RJ, Carlsen KCL, Carlsen K-H Rhinitis in children: co-morbidities and phenotypes. Pediatr Allergy Immunol 2010, 21:612-622.
39. Leynaert B, Neukirch C, Kony S, et al. Association between asthma and rhinitis according to atopic sensitization in a population-based study. J Allergy Clin Immunol 2004, 113:86-93.
40. Pearce N, Pekkanen J, Beasley R How much asthma is really attributable to atopy?. Thorax 1999, 54:268-272.
41. Arshad SH, Tariq SM, Matthews S, Hakim E Sensitization to common allergens and its association with allergic disorders at age 4 years: a whole population birth cohort study. Pediatrics 2001, 108:E33.
42. Saito H, Ishizaka T, Ishizaka K Mast cells and IgE: from history to today. Allergol Int 2013, 62:3-12.
43. Cruz AA, Popov T, Pawankar R, et al. Common characteristics of upper and lower airways in rhinitis and asthma: ARIA update, in collaboration with GA(2)LEN. Allergy 2007, 62(suppl 84):1-41.
44. Melén E, Pershagen G Pathophysiology of asthma: lessons from genetic research with particular focus on severe asthma. J Intern Med 2012, 272:108-120.
45. Dizier M-H, Margaritte-Jeannin P, Madore A-M, et al. The ANO3/MUC15 locus is associated with eczema in families ascertained through asthma. J Allergy Clin Immunol 2012, 129:1547. 53.e3.
46. Dizier M-H, Bouzigon E, Guilloud-Bataille M, et al. Evidence for a locus in 1p31 region specifically linked to the co-morbidity of asthma and allergic rhinitis in the EGEA study. Hum Hered 2007, 63:162-167.
47. Guilloud-Bataille M, Bouzigon E, Annesi-Maesano I, et al. Evidence for linkage of a new region (11p14) to eczema and allergic diseases. Hum Genet 2008, 122:605-614.
48. Heimall J, Spergel JM Filaggrin mutations and atopy: consequences for future therapeutics. Expert Rev Clin Immunol 2012, 8:189-197.
49. Bousquet J, Anto JM, Demoly P, et al. Severe chronic allergic (and related) diseases: a uniform approach-a MeDALL-GA2LEN-ARIA position paper. Int Arch Allergy Immunol 2012, 158:216-231.
50. Vance G, Lloyd K, Scadding G, et al. The 'unified airway': the RCPCH care pathway for children with asthma and/or rhinitis. Arch Dis Child 2011, 96(suppl 2):i10-i14.
51. Castro-Rodríguez JA, Holberg CJ, Wright AL, Martinez FD A clinical index to define risk of asthma in young children with recurrent wheezing. Am J Respir Crit Care Med 2000, 162:1403-1406.
52. Leonardi NA, Spycher BD, Strippoli M-PF, Frey U, Silverman M, Kuehni CE Validation of the Asthma Predictive Index and comparison with simpler clinical prediction rules. J Allergy Clin Immunol 2011, 127:1466. 72.e6.
53. Rachelefsky G, Farrar JR A control model to evaluate pharmacotherapy for allergic rhinitis in children. JAMA Pediatr 2013, 167:380-386.