Preliminary evaluation of different biomaterials for defect healing in an experimental osteoporotic rat model with dynamic PET-CT (dPET-CT) using F-18-Sodium Fluoride (NaF)

Injury

Volumn 45, Issue 3, 2014, Pages 501-505

  Cheng, Caixia ^a   Alt, Volker ^b   Pan, Leyun ^a   Thormann, Ulrich ^b   Schnettler, Reinhard ^b   Strauss, Ludwig G ^a   Schumacher, Matthias ^c   Gelinsky, Michael ^c   Dimitrakopoulou Strauss, Antonia ^a  

^a GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^b UNIVERSITY HOSPITAL GIESSEN   (Germany)

^c UNIVERSITY HOSPITAL CARL GUSTAV CARUS   (Germany)

Author keywords

18F Sodium Fluoride (NaF); Biomaterials; Bone defect; Osteoporosis; PET CT

Indexed keywords

BIOMATERIAL; BONE CEMENT; CALCIUM; CALCIUM PHOSPHATE; FLUORINE; SODIUM FLUORIDE;

ANIMAL; COMPUTER ASSISTED TOMOGRAPHY; DEFICIENCY; DIAGNOSTIC USE; FEMALE; FEMUR FRACTURE; MALE; OSTEOPOROSIS; OVARIECTOMY; PATHOLOGY; POSITRON EMISSION TOMOGRAPHY; RAT; REPRODUCIBILITY; SPRAGUE DAWLEY RAT;

ANIMALS; BIOCOMPATIBLE MATERIALS; BONE CEMENTS; CALCIUM; CALCIUM PHOSPHATES; FEMALE; FEMORAL FRACTURES; FLUORINE RADIOISOTOPES; MALE; OSTEOPOROSIS; OVARIECTOMY; POSITRON-EMISSION TOMOGRAPHY; RATS; RATS, SPRAGUE-DAWLEY; REPRODUCIBILITY OF RESULTS; SODIUM FLUORIDE; TOMOGRAPHY, X-RAY COMPUTED;

EID: 84895068774     PISSN: 00201383     EISSN: 18790267     Source Type: Journal    
DOI: 10.1016/j.injury.2013.11.023     Document Type: Article

References (37)

1. R. Agarwal, K. Williams, C.A. Umscheid, and W.C. Welch Osteoinductive bone graft substitutes for lumbar fusion: a systematic review J Neurosurg Spine 11 2009 729 740
2. C.J. Damien, and J.R. Parsons Bone graft and bone graft substitute: a review of current technology and applications J Appl Biomater 2 1991 187 208
3. Ar Gazdag, J.M. Lane, D. Glaser, and R.A. Forser Alternatives to autogenous bone graft: efficacy and indications J Am Acad Orthop Surg 3 1995 1 8
4. E. Nkenke, and F. Stelzle Clinical outcomes of sinus floor augmentation for implant placement using autogenous bone or bone substitutes: a systematic review Clin Oral Implants Res 4 20 Suppl. 2009 124 133
5. C. Capuccini, P. Torricelli, E. Boanini, M. Gazzano, R. Giardino, and A. Bigi Interaction of Sr-doped hydroxyapatite nanocrystals with osteoclast and osteoblast-like cells J Biomed Mater Res A 89 2009 594 600
6. M. Schumacher, A. Henß, M. Rohnke, and M. Gelinsky A novel and easy to prepare strontium(II) modified calcium phosphate bone cement with enhanced mechanical properties Acta Biomater 9 2013 7536 7544
7. J. Sorensen, G. Ullmark, B. Langstrom, and O. Nilsson Rapid bone and blood flow formation in impacted morselized allografts: positron emission tomography (PET) studies on allografts in 5 femoral component revision of total hip arthroplasty Acta Orthop Scand 74 2003 633 643
8. N. Narita, K. Kato, H. Nakagaki, N. Ohno, Y. Kameyama, and J.A. Weatherell Distribution of fluoride concentration in the rat's bone Calcif Tissue Int 46 1990 200 204
9. 18F-fluoride on osteoblasts Eur J Nucl Med Mol Imaging 33 2006 491 494
10. 18F-fluoride position emission tomography J Bone Miner Res 17 2002 854 859
11. 18F-fluoride Mol Imaging Biol 15 2012 336 344
12. C. Heiss, P. Govindarajan, G. Schlewitz, N. Hemdan, N. Schliefke, and V. Alt et al. Induction of osteoporosis with its influence on osteoporotic determinants and their interrelationships in rats by DEXA Med Sci Monit 18 2012 BR199 BR200
13. V. Alt, U. Thormann, S. Ray, D. Zahner, L. Dürselen, and K. Lips et al. A new metaphyseal bone defect model in osteoporotic rats to study biomaterials for the enhancement of bone healing in osteoporotic fractures Acta Biomater 9 2013 7035 7042
14. L.G. Strauss, and P.S. Conti The applications of PET in clinical oncology J Nucl Med 32 1991 623 648
15. K. Mikolajczyk, M. Szabatin, P. Rudnicki, M. Grodzki, and C. Burger A JAVA environment for medical image data analysis: initial application for brain PET quantitation Med Inform 23 1998 207 214
16. C. Burger, and A. Buck Requirements and implementations of a flexible kinetic modelling tool J Nucl Med 38 1997 181 1823
17. L.G. Strauss, L. Pan, D. Koczan, S. Klippel, K. Mikolajczyk, and C. Burger et al. Fusion of positron emission tomography (PET) and gene array data: a new approach for the correlative analysis of molecular biological and clinical data IEEE Trans Med Imaging 26 2007 804 812
18. A. Dimitrakopoulou-Strauss, L.G. Strauss, C. Burger, K. Mikolajczyk, T. Lehnert, and L. Bernd et al. On the fractal nature of dynamic positron emission tomography (PET) studies World J Nucl Med 2 2003 306 313
19. J.D. Currey Bones: Structure and Mechanics 2002 Princeton University Press
20. C. Combes, R. Bareille, and C. Rey Calcium carbonate-calcium phosphate mixed cement compositions for bone reconstruction J Biomed Mater Res A 79 2006 318 328
21. S. Tadier, N. Le Bolay, S. Girod Fullana, S. Cazalbou, C. Charvillat, and M. Labarrere et al. Co-grinding significance for calcium carbonate-calcium phosphate mixed cement. Part II: Effect on cement properties J Biomed Mater Res B 99B 2011 302 312
22. S. Tadier, R. Bareille, R. Siadous, O. Marsan, C. Charvillat, and S. Cazalbou et al. Strontium-loaded mineral bone cements as sustained release systems: compositions, release properties, and effects on human osteoprogenitor cells J Biomed Mater Res Part B 100B 2012 378 390
23. W. Hsu, B.T. Feeley, L. Krenek, B. Stout, A.F. Chatziioannou, and J.R. Lieberman et al. The use of 18F-fluoride and 18F-FDG pet scans to assess fracture healing in a rat femur model Eur J Nucl Med Mol Imaging 34 2007 1291 1301
24. G. Ullmark, J. Soerensen, and O. Nilsson Bone healing of severe acetabular defects after revision arthroplasty Acta Orthop 80 2009 170 183
25. M.J. Peltola, P. Vallittu, V. Vuorinen, A.A.J. Aho, A. Puntala, and K.M.J. Aitasalo Novel composite implant in craniofacial bone reconstruction Eur Arch Otorhinolaryngol 269 2012 623 628
26. J.K. Koort, T.J. Maekinen, E. Suokas, M. Veiranto, J. Jalava, and J. Knuuti et al. Efficacy of ciprofloxacin-releasing bioabsorbable osteoconductive bone defect filler for treatment of experimental osteomyelitis due to Staphylococcus aureus Antimicrob Agents Chemother 49 2005 1502 1508
27. I. Khairoun, M.G. Boltong, F.C. Driessens, and J.A. Planell Effect of calcium carbonate on the compliance of an apatitic calcium phosphate bone cement Biomater 18 1997 1535 1539
28. M. Schumacher, A. Lode, A. Helth, and M. Gelinsky A novel strontium(II)-modified calcium phosphate bone cement stimulates hMSC proliferation and osteogenic differentiation in vitro Acta Biomater 2013 10.1016/j.actbio.2013.07.027
29. U. Thormann, S. Ray, U. Sommer, T. Elkhassawna, T. Rehling, and M. Hundgeburth et al. Bone formation induced by strontium modified calcium phosphate cement in critical-size metaphyseal fracture defects in ovariectomized rats Biomaterials 2013 10.1016/j.biomaterials.2013.07.036
30. J. Kokesch-Himmelreich, M. Schumacher, M. Rohnke, M. Gelinsky, and J. Janek ToF-SIMS analysis of osteoblast-like cells and their mineralized extracellular matrix on strontium enriched bone cements Bionterphases 8 2013 17
31. M. Piert, T.T. Zittel, G.A. Becker, M. Jahn, A. Stahlschmidt, and G. Maier et al. Assessment of porcine bone metabolism by dynamic 18F-fluoride ion PET: correlation with bone histomorphometry J Nucl Med 42 2001 1091 1100
32. C. Messa, W.G. Goodman, C.K. Hoh, Y. Choi, A.R. Nissenson, and I.B. Salusky et al. Bone metabolic activity measured with positron emission tomography and 18F fluoride ion in renal osteodystrophy: correlation with bone histomorphometry J Clin Endocrinol Metab 77 1993 949 955
33. P.J. Marie, P. Ammann, G. Boivin, and C. Rey Mechanisms of action and therapeutic potential of strontium in bone Calcif Tissue Int 69 2001 121 129
34. E. Bonnelye, A. Chabadel, F. Saltel, and P. Jurdic Dual effect of strontium ranelate: stimulation of osteoblast differentiation and inhibition of osteoclast formation and resorption in vitro Bone 42 2008 129 138
35. C. Li, O. Paris, S. Siegel, P. Roschger, E.P. Paschalis, and K. Klaushofer et al. Strontium is incorporated into mineral crystals only in newly formed bone during strontium ranelate treatment J Bone Miner Res 25 2010 968 975
36. P.J. Marie Strontium ranelate: a physiological approach for optimizing bone formation and resorption Bone 38 2006 S10 S14
37. A. Dimitrakopoulou-Strauss, L.G. Strauss, and C. Burger Quantitative PET studies in pretreated melanoma patients: a comparison of 6-(18F)fluoro-l-dopa with 18F-FDG and (15)O-water using compartment and noncompartment analysis J Nucl Med 42 2001 248 256