MicroRNA-29a upregulates MMP2 in oral squamous cell carcinoma to promote cancer invasion and anti-apoptosis

Biomedicine and Pharmacotherapy

Volumn 68, Issue 1, 2014, Pages 13-19

  Lu, Le ^a   Xue, Xiaofeng ^b   Lan, Jing ^b   Gao, Yang ^b   Xiong, Zhenghui ^a   Zhang, Haiping ^a   Jiang, Wei ^a   Song, Weijian ^a   Zhi, Qiaoming ^b  

^a Suzhou Stomatological Hospital   (China)

^b THE FIRST AFFILIATED HOSPITAL OF SOOCHOW UNIVERSITY   (China)

Author keywords

Anti apoptosis; Invasion; MiR 29a; MMP2; OSCC

Indexed keywords

ANTI-APOPTOSIS; INVASION; MIR-29A; MMP2; OSCC;

3' UNTRANSLATED REGIONS; APOPTOSIS; CARCINOMA, SQUAMOUS CELL; CELL LINE, TUMOR; DISEASE PROGRESSION; GENE EXPRESSION REGULATION, NEOPLASTIC; GENE KNOCKDOWN TECHNIQUES; HUMANS; MATRIX METALLOPROTEINASE 2; MICRORNAS; MOUTH NEOPLASMS; NEOPLASM INVASIVENESS; TRANSFECTION; UP-REGULATION;

EID: 84895067735     PISSN: 07533322     EISSN: 19506007     Source Type: Journal    
DOI: 10.1016/j.biopha.2013.10.005     Document Type: Article

References (31)

1. Sharma P., Saxena S., Aggarwal P. Trends in the epidemiology of oral squamous cell carcinoma in Western UP: an institutional study. Indian J Dent Res 2010, 21:316-319.
2. Carvalho A.L., Singh B., Spiro R.H., Kowalski L.P., Shah J.P. Cancer of the oral cavity: a comparison between institutions in a developing and a developed nation. Head Neck 2004, 26:31-38.
3. Grimm M., Alexander D., Munz A., Hoffmann J., Reinert S. Increased LDH5 expression is associated with lymph node metastasis and outcome in oral squamous cell carcinoma. Clin Exp Metastasis 2013, 30:529-540.
4. Olasz L., Orsi E., Marko T., Szalma J. Induction chemotherapy response and recurrence rates in correlation with N0 or N+ stage in oral squamous cell cancer (OSCC). Cancer Metastasis Rev 2010, 29:607-611.
5. Yan K.H., Lee L.M., Yan S.H., et al. Tomatidine inhibits invasion of human lung adenocarcinoma cell A549 by reducing matrix metalloproteinases expression. Chem Biol Interact 2013, 203:580-587.
6. Yang C.C., Zhu L.F., Xu X.H., Ning T.Y., Ye J.H., Liu L.K. Membrane type 1 matrix metalloproteinase induces an epithelial to mesenchymal transition and cancer stem cell-like properties in SCC9 cells. BMC Cancer 2013, 13:171.
7. Yen C.Y., Chen C.H., Chang C.H., et al. Matrix metalloproteinases (MMP) 1 and MMP10 but not MMP12 are potential oral cancer markers. Biomarkers 2009, 14:244-249.
8. Kainuma K., Katsuno S., Hashimoto S., et al. Differences in the expression of genes between normal tissue and squamous cell carcinomas of head and neck using cancer-related gene cDNA microarray. Acta Otolaryngol 2006, 126:967-974.
9. Ye H., Yu T., Temam S., et al. Transcriptomic dissection of tongue squamous cell carcinoma. BMC Genomics 2008, 9:69.
10. Tamamura R., Nagatsuka H., Siar C.H., et al. Comparative analysis of basal lamina type IV collagen alpha chains, matrix metalloproteinases-2 and -9 expressions in oral dysplasia and invasive carcinoma. Acta Histochem 2013, 115:113-119.
11. Baker E.A., Leaper D.J., Hayter J.P., Dickenson A.J. The matrix metalloproteinase system in oral squamous cell carcinoma. Br J Oral Maxillofac Surg 2006, 44:482-486.
12. Lee R.C., Ambros V. An extensive class of small RNAs in Caenorhabditis elegans. Science 2001, 294:862-864.
13. Lagos-Quintana M., Rauhut R., Lendeckel W., Tuschl T. Identification of novel genes coding for small expressed RNAs. Science 2001, 294:853-858.
14. Bartel D.P. MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 2004, 116:281-297.
15. Jackson R.J., Standart N. How do microRNAs regulate gene expression?. Sci STKE 2007, re1.
16. Bueno M.J., Perez de Castro I., Malumbres M. Control of cell proliferation pathways by microRNAs. Cell Cycle 2008, 7:3143-3148.
17. Rather M.I., Nagashri M.N., Swamy S.S., Gopinath K.S., Kumar A. Oncogenic microRNA-155 down-regulates tumor suppressor CDC73 and promotes oral squamous cell carcinoma cell proliferation: implications for cancer therapeutics. J Biol Chem 2013, 288:608-618.
18. Shiiba M., Shinozuka K., Saito K., et al. MicroRNA-125b regulates proliferation and radioresistance of oral squamous cell carcinoma. Br J Cancer 2013, 108:1817-1821.
19. Endo H., Muramatsu T., Furuta M., et al. Potential of tumor-suppressive miR-596 targeting LGALS3BP as a therapeutic agent in oral cancer. Carcinogenesis 2013, 34:560-569.
20. Uesugi A., Kozaki K., Tsuruta T., et al. The tumor suppressive microRNA miR-218 targets the mTOR component Rictor and inhibits AKT phosphorylation in oral cancer. Cancer Res 2011, 71:5765-5778.
21. Rautava J., Luukkaa M., Heikinheimo K., Alin J., Grenman R., Happonen R.P. Squamous cell carcinomas arising from different types of oral epithelia differ in their tumor and patient characteristics and survival. Oral Oncol 2007, 43:911-919.
22. Mehrotra R., Singh M.K., Pandya S., Singh M. The use of an oral brush biopsy without computer-assisted analysis in the evaluation of oral lesions: a study of 94 patients. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2008, 106:246-253.
23. Peng C.H., Liao C.T., Peng S.C., et al. A novel molecular signature identified by systems genetics approach predicts prognosis in oral squamous cell carcinoma. PLoS One 2011, 6:e23452.
24. Chen R., Yang K., Zhao N.B., et al. Abnormal expression of PER1 circadian-clock gene in oral squamous cell carcinoma. Onco Targets Ther 2012, 5:403-407.
25. Lohavanichbutr P., Houck J., Doody D.R., et al. Gene expression in uninvolved oral mucosa of OSCC patients facilitates identification of markers predictive of OSCC outcomes. PLoS One 2012, 7:e46575.
26. Hsu D.S., Chang S.Y., Liu C.J., et al. Identification of increased NBS1 expression as a prognostic marker of squamous cell carcinoma of the oral cavity. Cancer Sci 2010, 101:1029-1037.
27. Kunej T., Godnic I., Ferdin J., Horvat S., Dovc P., Calin G.A. Epigenetic regulation of microRNAs in cancer: an integrated review of literature. Mutat Res 2011, 717:77-84.
28. Jiang Y.W., Chen L.A. microRNAs as tumor inhibitors, oncogenes, biomarkers for drug efficacy and outcome predictors in lung cancer (review). Mol Med Rep 2012, 5:890-894.
29. Perrotti D., Eiring A.M. The new role of microRNAs in cancer. Future Oncol 2010, 6:1203-1206.
30. Maclellan S.A., Lawson J., Baik J., Guillaud M., Poh C.F., Garnis C. Differential expression of miRNAs in the serum of patients with high-risk oral lesions. Cancer Med 2012, 1:268-274.
31. Wang Y., Zhang X., Li H., Yu J., Ren X. The role of miRNA-29 family in cancer. Eur J Cell Biol 2013, 92:123-128.