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Volumn 43, Issue 4, 2014, Pages 447-457

Comparative effectiveness and survival of infliximab, adalimumab, and etanercept for rheumatoid arthritis patients in the Hellenic Registry of Biologics: Low rates of remission and 5-year drug survival

Author keywords

Arthritis; Biological therapies; Efficacy; Glucocorticoids; Infections; Registry; Safety

Indexed keywords

ARTHRITIS; BIOLOGICAL THERAPIES; EFFICACY; GLUCOCORTICOIDS; INFECTIONS; REGISTRY; SAFETY;

EID: 84894903634     PISSN: 00490172     EISSN: 1532866X     Source Type: Journal    
DOI: 10.1016/j.semarthrit.2013.07.011     Document Type: Article
Times cited : (79)

References (45)
  • 1
    • 33845882484 scopus 로고    scopus 로고
    • Biologic therapies in rheumatology: lessons learned, future directions
    • Strand V., Kimberly R., Isaacs J.D. Biologic therapies in rheumatology: lessons learned, future directions. Nat Rev Drug Discov 2007, 6(1):75-92.
    • (2007) Nat Rev Drug Discov , vol.6 , Issue.1 , pp. 75-92
    • Strand, V.1    Kimberly, R.2    Isaacs, J.D.3
  • 2
    • 38749141455 scopus 로고    scopus 로고
    • Systematic review: comparative effectiveness and harms of disease-modifying medications for rheumatoid arthritis
    • Donahue K.E., Gartlehner G., Jonas D.E., Lux L.J., Thieda P., Jonas B.L., et al. Systematic review: comparative effectiveness and harms of disease-modifying medications for rheumatoid arthritis. Ann Intern Med 2008, 148(2):124-134.
    • (2008) Ann Intern Med , vol.148 , Issue.2 , pp. 124-134
    • Donahue, K.E.1    Gartlehner, G.2    Jonas, D.E.3    Lux, L.J.4    Thieda, P.5    Jonas, B.L.6
  • 3
    • 72949116165 scopus 로고    scopus 로고
    • A network meta-analysis of randomized controlled trials of biologics for rheumatoid arthritis: a Cochrane overview
    • Singh J.A., Christensen R., Wells G.A., Suarez-Almazor M.E., Buchbinder R., Lopez-Olivo M.A., et al. A network meta-analysis of randomized controlled trials of biologics for rheumatoid arthritis: a Cochrane overview. Can Med Assoc J 2009, 181(11):787-796.
    • (2009) Can Med Assoc J , vol.181 , Issue.11 , pp. 787-796
    • Singh, J.A.1    Christensen, R.2    Wells, G.A.3    Suarez-Almazor, M.E.4    Buchbinder, R.5    Lopez-Olivo, M.A.6
  • 5
    • 58649083487 scopus 로고    scopus 로고
    • From randomized controlled trials to observational studies
    • Silverman S.L. From randomized controlled trials to observational studies. Am J Med 2009, 122(2):114-120.
    • (2009) Am J Med , vol.122 , Issue.2 , pp. 114-120
    • Silverman, S.L.1
  • 6
    • 50249107555 scopus 로고    scopus 로고
    • The effectiveness and medication costs of three anti-tumour necrosis factor alpha agents in the treatment of rheumatoid arthritis from prospective clinical practice data
    • Kievit W., Adang E.M., Fransen J., Kuper H.H., van de Laar M.A., Jansen T.L., et al. The effectiveness and medication costs of three anti-tumour necrosis factor alpha agents in the treatment of rheumatoid arthritis from prospective clinical practice data. Ann Rheum Dis 2008, 67(9):1229-1234.
    • (2008) Ann Rheum Dis , vol.67 , Issue.9 , pp. 1229-1234
    • Kievit, W.1    Adang, E.M.2    Fransen, J.3    Kuper, H.H.4    van de Laar, M.A.5    Jansen, T.L.6
  • 7
    • 74849094402 scopus 로고    scopus 로고
    • Direct comparison of treatment responses, remission rates, and drug adherence in patients with rheumatoid arthritis treated with adalimumab, etanercept, or infliximab: results from eight years of surveillance of clinical practice in the nationwide Danish DANBIO registry
    • Hetland M.L., Christensen I.J., Tarp U., Dreyer L., Hansen A., Hansen I.T., et al. Direct comparison of treatment responses, remission rates, and drug adherence in patients with rheumatoid arthritis treated with adalimumab, etanercept, or infliximab: results from eight years of surveillance of clinical practice in the nationwide Danish DANBIO registry. Arthritis Rheum 2010, 62(1):22-32.
    • (2010) Arthritis Rheum , vol.62 , Issue.1 , pp. 22-32
    • Hetland, M.L.1    Christensen, I.J.2    Tarp, U.3    Dreyer, L.4    Hansen, A.5    Hansen, I.T.6
  • 8
    • 84867809188 scopus 로고    scopus 로고
    • Comparative effectiveness and predictors of response to tumour necrosis factor inhibitor therapies in rheumatoid arthritis
    • Canhao H., Rodrigues A.M., Mourao A.F., Martins F., Santos M.J., Canas-Silva J., et al. Comparative effectiveness and predictors of response to tumour necrosis factor inhibitor therapies in rheumatoid arthritis. Rheumatology (Oxford) 2012, 51(11):2020-2026.
    • (2012) Rheumatology (Oxford) , vol.51 , Issue.11 , pp. 2020-2026
    • Canhao, H.1    Rodrigues, A.M.2    Mourao, A.F.3    Martins, F.4    Santos, M.J.5    Canas-Silva, J.6
  • 9
    • 84862563304 scopus 로고    scopus 로고
    • A comparative effectiveness study of adalimumab, etanercept and infliximab in biologically naive and switched rheumatoid arthritis patients: results from the US CORRONA registry
    • Greenberg J.D., Reed G., Decktor D., Harrold L., Furst D., Gibofsky A., et al. A comparative effectiveness study of adalimumab, etanercept and infliximab in biologically naive and switched rheumatoid arthritis patients: results from the US CORRONA registry. Ann Rheum Dis 2012, 71(7):1134-1142.
    • (2012) Ann Rheum Dis , vol.71 , Issue.7 , pp. 1134-1142
    • Greenberg, J.D.1    Reed, G.2    Decktor, D.3    Harrold, L.4    Furst, D.5    Gibofsky, A.6
  • 10
    • 79952452325 scopus 로고    scopus 로고
    • TNF-alpha antagonist use and risk of hospitalization for infection in a national cohort of veterans with rheumatoid arthritis
    • Lane M.A., McDonald J.R., Zeringue A.L., Caplan L., Curtis J.R., Ranganathan P., et al. TNF-alpha antagonist use and risk of hospitalization for infection in a national cohort of veterans with rheumatoid arthritis. Medicine (Baltimore) 2011, 90(2):139-145.
    • (2011) Medicine (Baltimore) , vol.90 , Issue.2 , pp. 139-145
    • Lane, M.A.1    McDonald, J.R.2    Zeringue, A.L.3    Caplan, L.4    Curtis, J.R.5    Ranganathan, P.6
  • 11
    • 83055173186 scopus 로고    scopus 로고
    • Initiation of tumor necrosis factor-alpha antagonists and the risk of hospitalization for infection in patients with autoimmune diseases
    • Grijalva C.G., Chen L., Delzell E., Baddley J.W., Beukelman T., Winthrop K.L., et al. Initiation of tumor necrosis factor-alpha antagonists and the risk of hospitalization for infection in patients with autoimmune diseases. J Am Med Assoc 2011, 306(21):2331-2339.
    • (2011) J Am Med Assoc , vol.306 , Issue.21 , pp. 2331-2339
    • Grijalva, C.G.1    Chen, L.2    Delzell, E.3    Baddley, J.W.4    Beukelman, T.5    Winthrop, K.L.6
  • 12
    • 84877598742 scopus 로고    scopus 로고
    • Difference in the risk of serious infections in patients with rheumatoid arthritis treated with adalimumab, infliximab and etanercept: results from the Dutch Rheumatoid Arthritis Monitoring (DREAM) registry
    • van Dartel S.A., Fransen J., Kievit W., Flendrie M., den Broeder A.A., Visser H., et al. Difference in the risk of serious infections in patients with rheumatoid arthritis treated with adalimumab, infliximab and etanercept: results from the Dutch Rheumatoid Arthritis Monitoring (DREAM) registry. Ann Rheum Dis. 2012.
    • (2012) Ann Rheum Dis.
    • van Dartel, S.A.1    Fransen, J.2    Kievit, W.3    Flendrie, M.4    den Broeder, A.A.5    Visser, H.6
  • 13
    • 79959978514 scopus 로고    scopus 로고
    • Persistence with anti-tumor necrosis factor therapies in patients with rheumatoid arthritis: observations from the RADIUS registry
    • Markenson J.A., Gibofsky A., Palmer W.R., Keystone E.C., Schiff M.H., Feng J., et al. Persistence with anti-tumor necrosis factor therapies in patients with rheumatoid arthritis: observations from the RADIUS registry. J Rheumatol 2011, 38(7):1273-1281.
    • (2011) J Rheumatol , vol.38 , Issue.7 , pp. 1273-1281
    • Markenson, J.A.1    Gibofsky, A.2    Palmer, W.R.3    Keystone, E.C.4    Schiff, M.H.5    Feng, J.6
  • 14
    • 83055181868 scopus 로고    scopus 로고
    • Age at treatment predicts reason for discontinuation of TNF antagonists: data from the BIOBADASER 2.0 registry
    • Busquets N., Tomero E., Descalzo M.A., Ponce A., Ortiz-Santamaria V., Suris X., et al. Age at treatment predicts reason for discontinuation of TNF antagonists: data from the BIOBADASER 2.0 registry. Rheumatology (Oxford) 2011, 50(11):1999-2004.
    • (2011) Rheumatology (Oxford) , vol.50 , Issue.11 , pp. 1999-2004
    • Busquets, N.1    Tomero, E.2    Descalzo, M.A.3    Ponce, A.4    Ortiz-Santamaria, V.5    Suris, X.6
  • 15
    • 84870253476 scopus 로고    scopus 로고
    • Long-term anti-TNF therapy and the risk of serious infections in a cohort of patients with rheumatoid arthritis: comparison of adalimumab, etanercept and infliximab in the GISEA registry
    • Atzeni F., Sarzi-Puttini P., Botsios C., Carletto A., Cipriani P., Favalli E.G., et al. Long-term anti-TNF therapy and the risk of serious infections in a cohort of patients with rheumatoid arthritis: comparison of adalimumab, etanercept and infliximab in the GISEA registry. Autoimmun Rev 2012, 12(2):225-229.
    • (2012) Autoimmun Rev , vol.12 , Issue.2 , pp. 225-229
    • Atzeni, F.1    Sarzi-Puttini, P.2    Botsios, C.3    Carletto, A.4    Cipriani, P.5    Favalli, E.G.6
  • 16
    • 84861811932 scopus 로고    scopus 로고
    • Longterm retention of tumor necrosis factor-alpha inhibitor therapy in a large italian cohort of patients with rheumatoid arthritis from the GISEA registry: an appraisal of predictors
    • Iannone F., Gremese E., Atzeni F., Biasi D., Botsios C., Cipriani P., et al. Longterm retention of tumor necrosis factor-alpha inhibitor therapy in a large italian cohort of patients with rheumatoid arthritis from the GISEA registry: an appraisal of predictors. J Rheumatol 2012, 39(6):1179-1184.
    • (2012) J Rheumatol , vol.39 , Issue.6 , pp. 1179-1184
    • Iannone, F.1    Gremese, E.2    Atzeni, F.3    Biasi, D.4    Botsios, C.5    Cipriani, P.6
  • 17
    • 0029113092 scopus 로고
    • Rheumatoid arthritis in Greece: clinical, serological and genetic considerations
    • Drosos A.A., Moutsopoulos H.M. Rheumatoid arthritis in Greece: clinical, serological and genetic considerations. Clin Exp Rheumatol 1995, 13(Suppl. 12):S7-S12.
    • (1995) Clin Exp Rheumatol , vol.13 , Issue.SUPPL. 12
    • Drosos, A.A.1    Moutsopoulos, H.M.2
  • 18
    • 85019248298 scopus 로고    scopus 로고
    • Update of the recommendations for the use of biological agents in rheumatoid arthritis and spondyloarthropathies [article in greek]
    • Sidiropoulos P., Flouri I. Update of the recommendations for the use of biological agents in rheumatoid arthritis and spondyloarthropathies [article in greek]. Hellenic Rheumatol 2008, 19(4):291-310.
    • (2008) Hellenic Rheumatol , vol.19 , Issue.4 , pp. 291-310
    • Sidiropoulos, P.1    Flouri, I.2
  • 19
    • 0036720662 scopus 로고    scopus 로고
    • Etanercept, infliximab, and leflunomide in established rheumatoid arthritis: clinical experience using a structured follow up programme in southern Sweden
    • Geborek P., Crnkic M., Petersson I.F., Saxne T. Etanercept, infliximab, and leflunomide in established rheumatoid arthritis: clinical experience using a structured follow up programme in southern Sweden. Ann Rheum Dis 2002, 61(9):793-798.
    • (2002) Ann Rheum Dis , vol.61 , Issue.9 , pp. 793-798
    • Geborek, P.1    Crnkic, M.2    Petersson, I.F.3    Saxne, T.4
  • 20
    • 84859853303 scopus 로고    scopus 로고
    • Rheumatoid arthritis disease activity measures: American College of Rheumatology recommendations for use in clinical practice
    • Anderson J., Caplan L., Yazdany J., Robbins M.L., Neogi T., Michaud K., et al. Rheumatoid arthritis disease activity measures: American College of Rheumatology recommendations for use in clinical practice. Arthritis Care Res (Hoboken) 2012, 64(5):640-647.
    • (2012) Arthritis Care Res (Hoboken) , vol.64 , Issue.5 , pp. 640-647
    • Anderson, J.1    Caplan, L.2    Yazdany, J.3    Robbins, M.L.4    Neogi, T.5    Michaud, K.6
  • 21
    • 0035011581 scopus 로고    scopus 로고
    • Standardizing assessment of adverse effects in rheumatology clinical trials. Status of OMERACT Toxicity Working Group March 2000: towards a common understanding of comparative toxicity/safety profiles for antirheumatic therapies
    • Woodworth T., Furst D., Strand V., Kempeni J., Fenner H., Lau C., et al. Standardizing assessment of adverse effects in rheumatology clinical trials. Status of OMERACT Toxicity Working Group March 2000: towards a common understanding of comparative toxicity/safety profiles for antirheumatic therapies. J Rheumatol 2001, 28(5):1163-1172.
    • (2001) J Rheumatol , vol.28 , Issue.5 , pp. 1163-1172
    • Woodworth, T.1    Furst, D.2    Strand, V.3    Kempeni, J.4    Fenner, H.5    Lau, C.6
  • 22
    • 77953696525 scopus 로고    scopus 로고
    • EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatic drugs
    • Smolen J.S., Landewe R., Breedveld F.C., Dougados M., Emery P., Gaujoux-Viala C., et al. EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatic drugs. Ann Rheum Dis 2010, 69(6):964-975.
    • (2010) Ann Rheum Dis , vol.69 , Issue.6 , pp. 964-975
    • Smolen, J.S.1    Landewe, R.2    Breedveld, F.C.3    Dougados, M.4    Emery, P.5    Gaujoux-Viala, C.6
  • 23
    • 0028815803 scopus 로고
    • Modified disease activity scores that include twenty-eight-joint counts. Development and validation in a prospective longitudinal study of patients with rheumatoid arthritis
    • Prevoo M.L., van't Hof M.A., Kuper H.H., van Leeuwen M.A., van de Putte L.B., van Riel P.L. Modified disease activity scores that include twenty-eight-joint counts. Development and validation in a prospective longitudinal study of patients with rheumatoid arthritis. Arthritis Rheum 1995, 38(1):44-48.
    • (1995) Arthritis Rheum , vol.38 , Issue.1 , pp. 44-48
    • Prevoo, M.L.1    van't Hof, M.A.2    Kuper, H.H.3    van Leeuwen, M.A.4    van de Putte, L.B.5    van Riel, P.L.6
  • 24
    • 34547400142 scopus 로고    scopus 로고
    • The Simplified Disease Activity Index (SDAI) and Clinical Disease Activity Index (CDAI) to monitor patients in standard clinical care
    • Aletaha D., Smolen J.S. The Simplified Disease Activity Index (SDAI) and Clinical Disease Activity Index (CDAI) to monitor patients in standard clinical care. Best Pract Res Clin Rheumatol 2007, 21(4):663-675.
    • (2007) Best Pract Res Clin Rheumatol , vol.21 , Issue.4 , pp. 663-675
    • Aletaha, D.1    Smolen, J.S.2
  • 25
    • 79953752083 scopus 로고    scopus 로고
    • American College of Rheumatology/European League Against Rheumatism provisional definition of remission in rheumatoid arthritis for clinical trials
    • Felson D.T., Smolen J.S., Wells G., Zhang B., van Tuyl L.H., Funovits J., et al. American College of Rheumatology/European League Against Rheumatism provisional definition of remission in rheumatoid arthritis for clinical trials. Arthritis Rheum 2011, 63(3):573-586.
    • (2011) Arthritis Rheum , vol.63 , Issue.3 , pp. 573-586
    • Felson, D.T.1    Smolen, J.S.2    Wells, G.3    Zhang, B.4    van Tuyl, L.H.5    Funovits, J.6
  • 26
    • 0030068817 scopus 로고    scopus 로고
    • Development and validation of the European League Against Rheumatism response criteria for rheumatoid arthritis. Comparison with the preliminary American College of Rheumatology and the World Health Organization/International League Against Rheumatism Criteria
    • van Gestel A.M., Prevoo M.L., van't Hof M.A., van Rijswijk M.H., van de Putte L.B., van Riel P.L. Development and validation of the European League Against Rheumatism response criteria for rheumatoid arthritis. Comparison with the preliminary American College of Rheumatology and the World Health Organization/International League Against Rheumatism Criteria. Arthritis Rheum 1996, 39(1):34-40.
    • (1996) Arthritis Rheum , vol.39 , Issue.1 , pp. 34-40
    • van Gestel, A.M.1    Prevoo, M.L.2    van't Hof, M.A.3    van Rijswijk, M.H.4    van de Putte, L.B.5    van Riel, P.L.6
  • 27
    • 84862560815 scopus 로고    scopus 로고
    • Definition of treatment response in rheumatoid arthritis based on the simplified and the clinical disease activity index
    • Aletaha D., Martinez-Avila J., Kvien T.K., Smolen J.S. Definition of treatment response in rheumatoid arthritis based on the simplified and the clinical disease activity index. Ann Rheum Dis 2012, 71(7):1190-1196.
    • (2012) Ann Rheum Dis , vol.71 , Issue.7 , pp. 1190-1196
    • Aletaha, D.1    Martinez-Avila, J.2    Kvien, T.K.3    Smolen, J.S.4
  • 28
    • 0029044362 scopus 로고
    • American College of Rheumatology. Preliminary definition of improvement in rheumatoid arthritis
    • Felson D.T., Anderson J.J., Boers M., Bombardier C., Furst D., Goldsmith C., et al. American College of Rheumatology. Preliminary definition of improvement in rheumatoid arthritis. Arthritis Rheum 1995, 38(6):727-735.
    • (1995) Arthritis Rheum , vol.38 , Issue.6 , pp. 727-735
    • Felson, D.T.1    Anderson, J.J.2    Boers, M.3    Bombardier, C.4    Furst, D.5    Goldsmith, C.6
  • 29
    • 32444443730 scopus 로고    scopus 로고
    • The LUNDEX, a new index of drug efficacy in clinical practice: results of a five-year observational study of treatment with infliximab and etanercept among rheumatoid arthritis patients in southern Sweden
    • Kristensen L.E., Saxne T., Geborek P. The LUNDEX, a new index of drug efficacy in clinical practice: results of a five-year observational study of treatment with infliximab and etanercept among rheumatoid arthritis patients in southern Sweden. Arthritis Rheum 2006, 54(2):600-606.
    • (2006) Arthritis Rheum , vol.54 , Issue.2 , pp. 600-606
    • Kristensen, L.E.1    Saxne, T.2    Geborek, P.3
  • 31
    • 33751416149 scopus 로고    scopus 로고
    • Predictors of response to anti-TNF-alpha therapy among patients with rheumatoid arthritis: results from the British Society for Rheumatology Biologics Register
    • Hyrich K.L., Watson K.D., Silman A.J., Symmons D.P. Predictors of response to anti-TNF-alpha therapy among patients with rheumatoid arthritis: results from the British Society for Rheumatology Biologics Register. Rheumatology (Oxford) 2006, 45(12):1558-1565.
    • (2006) Rheumatology (Oxford) , vol.45 , Issue.12 , pp. 1558-1565
    • Hyrich, K.L.1    Watson, K.D.2    Silman, A.J.3    Symmons, D.P.4
  • 32
    • 43049169008 scopus 로고    scopus 로고
    • Predictors of response to anti-TNF therapy according to ACR and EULAR criteria in patients with established RA: results from the South Swedish Arthritis Treatment Group Register
    • Kristensen L.E., Kapetanovic M.C., Gulfe A., Soderlin M., Saxne T., Geborek P. Predictors of response to anti-TNF therapy according to ACR and EULAR criteria in patients with established RA: results from the South Swedish Arthritis Treatment Group Register. Rheumatology (Oxford) 2008, 47(4):495-499.
    • (2008) Rheumatology (Oxford) , vol.47 , Issue.4 , pp. 495-499
    • Kristensen, L.E.1    Kapetanovic, M.C.2    Gulfe, A.3    Soderlin, M.4    Saxne, T.5    Geborek, P.6
  • 33
    • 66249124273 scopus 로고    scopus 로고
    • Comparison of drug retention rates and causes of drug discontinuation between anti-tumor necrosis factor agents in rheumatoid arthritis
    • Du Pan S.M., Dehler S., Ciurea A., Ziswiler H.R., Gabay C., Finckh A. Comparison of drug retention rates and causes of drug discontinuation between anti-tumor necrosis factor agents in rheumatoid arthritis. Arthritis Rheum 2009, 61(5):560-568.
    • (2009) Arthritis Rheum , vol.61 , Issue.5 , pp. 560-568
    • Du Pan, S.M.1    Dehler, S.2    Ciurea, A.3    Ziswiler, H.R.4    Gabay, C.5    Finckh, A.6
  • 34
    • 36749002002 scopus 로고    scopus 로고
    • Impact of concomitant DMARD therapy on adherence to treatment with etanercept and infliximab in rheumatoid arthritis. Results from a six-year observational study in southern Sweden
    • Kristensen L.E., Saxne T., Nilsson J.A., Geborek P. Impact of concomitant DMARD therapy on adherence to treatment with etanercept and infliximab in rheumatoid arthritis. Results from a six-year observational study in southern Sweden. Arthritis Res Ther 2006, 8(6):R174.
    • (2006) Arthritis Res Ther , vol.8 , Issue.6
    • Kristensen, L.E.1    Saxne, T.2    Nilsson, J.A.3    Geborek, P.4
  • 35
    • 65649093727 scopus 로고    scopus 로고
    • Six and 12 weeks treatment response predicts continuation of tumor necrosis factor blockade in rheumatoid arthritis: an observational cohort study from southern Sweden
    • Gulfe A., Kristensen L.E., Geborek P. Six and 12 weeks treatment response predicts continuation of tumor necrosis factor blockade in rheumatoid arthritis: an observational cohort study from southern Sweden. J Rheumatol 2009, 36(3):517-521.
    • (2009) J Rheumatol , vol.36 , Issue.3 , pp. 517-521
    • Gulfe, A.1    Kristensen, L.E.2    Geborek, P.3
  • 37
    • 84859517687 scopus 로고    scopus 로고
    • Remission and radiographic outcome in rheumatoid arthritis: application of the 2011 ACR/EULAR remission criteria in an observational cohort
    • Lillegraven S., Prince F.H., Shadick N.A., Bykerk V.P., Lu B., Frits M.L., et al. Remission and radiographic outcome in rheumatoid arthritis: application of the 2011 ACR/EULAR remission criteria in an observational cohort. Ann Rheum Dis. 2012, 71(5):681-686.
    • (2012) Ann Rheum Dis. , vol.71 , Issue.5 , pp. 681-686
    • Lillegraven, S.1    Prince, F.H.2    Shadick, N.A.3    Bykerk, V.P.4    Lu, B.5    Frits, M.L.6
  • 38
    • 84855166600 scopus 로고    scopus 로고
    • Sustained clinical remission in rheumatoid arthritis: prevalence and prognostic factors in an inception cohort of patients treated with conventional DMARDS
    • Jayakumar K., Norton S., Dixey J., James D., Gough A., Williams P., et al. Sustained clinical remission in rheumatoid arthritis: prevalence and prognostic factors in an inception cohort of patients treated with conventional DMARDS. Rheumatology (Oxford) 2012, 51(1):169-175.
    • (2012) Rheumatology (Oxford) , vol.51 , Issue.1 , pp. 169-175
    • Jayakumar, K.1    Norton, S.2    Dixey, J.3    James, D.4    Gough, A.5    Williams, P.6
  • 39
    • 84867405325 scopus 로고    scopus 로고
    • Drug retention rates and relevant risk factors for drug discontinuation due to adverse events in rheumatoid arthritis patients receiving anticytokine therapy with different target molecules
    • Sakai R., Tanaka M., Nanki T., Watanabe K., Yamazaki H., Koike R., et al. Drug retention rates and relevant risk factors for drug discontinuation due to adverse events in rheumatoid arthritis patients receiving anticytokine therapy with different target molecules. Ann Rheum Dis. 2012, 71(11):1820-1826.
    • (2012) Ann Rheum Dis. , vol.71 , Issue.11 , pp. 1820-1826
    • Sakai, R.1    Tanaka, M.2    Nanki, T.3    Watanabe, K.4    Yamazaki, H.5    Koike, R.6
  • 40
    • 48549099538 scopus 로고    scopus 로고
    • Treatment persistence with adalimumab, etanercept, or infliximab in combination with methotrexate and the effects on health care costs in patients with rheumatoid arthritis
    • Tang B., Rahman M., Waters H.C., Callegari P. Treatment persistence with adalimumab, etanercept, or infliximab in combination with methotrexate and the effects on health care costs in patients with rheumatoid arthritis. Clin Ther 2008, 30(7):1375-1384.
    • (2008) Clin Ther , vol.30 , Issue.7 , pp. 1375-1384
    • Tang, B.1    Rahman, M.2    Waters, H.C.3    Callegari, P.4
  • 41
    • 79959994678 scopus 로고    scopus 로고
    • Incidence and risk factors for serious infection in patients with rheumatoid arthritis treated with tumor necrosis factor inhibitors: a report from the Registry of Japanese Rheumatoid Arthritis Patients for Longterm Safety
    • Komano Y., Tanaka M., Nanki T., Koike R., Sakai R., Kameda H., et al. Incidence and risk factors for serious infection in patients with rheumatoid arthritis treated with tumor necrosis factor inhibitors: a report from the Registry of Japanese Rheumatoid Arthritis Patients for Longterm Safety. J Rheumatol 2011, 38(7):1258-1264.
    • (2011) J Rheumatol , vol.38 , Issue.7 , pp. 1258-1264
    • Komano, Y.1    Tanaka, M.2    Nanki, T.3    Koike, R.4    Sakai, R.5    Kameda, H.6
  • 42
    • 84864422138 scopus 로고    scopus 로고
    • Time-dependent increased risk for serious infection from continuous use of tumor necrosis factor antagonists over three years in patients with rheumatoid arthritis
    • Sakai R., Komano Y., Tanaka M., Nanki T., Koike R., Nagasawa H., et al. Time-dependent increased risk for serious infection from continuous use of tumor necrosis factor antagonists over three years in patients with rheumatoid arthritis. Arthritis Care Res (Hoboken) 2012, 64(8):1125-1134.
    • (2012) Arthritis Care Res (Hoboken) , vol.64 , Issue.8 , pp. 1125-1134
    • Sakai, R.1    Komano, Y.2    Tanaka, M.3    Nanki, T.4    Koike, R.5    Nagasawa, H.6
  • 43
    • 79959790816 scopus 로고    scopus 로고
    • The comparative risk of serious infections among rheumatoid arthritis patients starting or switching biological agents
    • Curtis J.R., Xie F., Chen L., Baddley J.W., Beukelman T., Saag K.G., et al. The comparative risk of serious infections among rheumatoid arthritis patients starting or switching biological agents. Ann Rheum Dis 2011, 70(8):1401-1406.
    • (2011) Ann Rheum Dis , vol.70 , Issue.8 , pp. 1401-1406
    • Curtis, J.R.1    Xie, F.2    Chen, L.3    Baddley, J.W.4    Beukelman, T.5    Saag, K.G.6
  • 44
    • 79951712039 scopus 로고    scopus 로고
    • Anti-TNF therapy is associated with an increased risk of serious infections in patients with rheumatoid arthritis especially in the first 6 months of treatment: updated results from the British Society for Rheumatology Biologics Register with special emphasis on risks in the elderly
    • Galloway J.B., Hyrich K.L., Mercer L.K., Dixon W.G., Fu B., Ustianowski A.P., et al. Anti-TNF therapy is associated with an increased risk of serious infections in patients with rheumatoid arthritis especially in the first 6 months of treatment: updated results from the British Society for Rheumatology Biologics Register with special emphasis on risks in the elderly. Rheumatology (Oxford) 2011, 50(1):124-131.
    • (2011) Rheumatology (Oxford) , vol.50 , Issue.1 , pp. 124-131
    • Galloway, J.B.1    Hyrich, K.L.2    Mercer, L.K.3    Dixon, W.G.4    Fu, B.5    Ustianowski, A.P.6
  • 45
    • 41549117102 scopus 로고    scopus 로고
    • Observational research, randomised trials, and two views of medical science
    • Vandenbroucke J.P. Observational research, randomised trials, and two views of medical science. PLoS Med 2008, 5(3):e67.
    • (2008) PLoS Med , vol.5 , Issue.3
    • Vandenbroucke, J.P.1


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