Sustained clinical remission in rheumatoid arthritis: Prevalence and prognostic factors in an inception cohort of patients treated with conventional DMARDS

Rheumatology

Volumn 51, Issue 1, 2012, Pages 169-175

  Jayakumar, Keeranur ^a   Norton, Sam ^b   Dixey, Josh ^c   James, David ^d   Gough, Andrew ^e   Williams, Peter ^f   Prouse, Peter ^g   Young, Adam ^a   Davies, Paul ^h   Hill, Lynn ^h   Devlin, Jo ^h   Emery, Paul ^h   Waterhouse, Lynn ^h   Tate, Helen ^h   Boys, Cathy ^h   White, Dora ^h   Dart, Helen ^h   Stafford, Sue ^h   Winfield, John ^h   Seymour, Annie ^h   Mayes, Cathy ^h   Hunt, Marie ^h   more..

^a St Albans City Hospital   (United Kingdom)

^b UNIVERSITY OF HERTFORDSHIRE   (United Kingdom)

^c NEW CROSS HOSPITAL   (United Kingdom)

^d DIANA PRINCESS OF WALES HOSPITAL   (United Kingdom)

^e HARROGATE DISTRICT HOSPITAL   (United Kingdom)

^f MEDWAY MARITIME HOSPITAL   (United Kingdom)

^g ROYAL BERKSHIRE HOSPITAL   (United Kingdom)

^h NONE

Author keywords

Clinical remission; Functional outcome; HAQ; Prognosis; Rheumatoid arthritis; X rays

Indexed keywords

DISEASE MODIFYING ANTIRHEUMATIC DRUG; STEROID;

ADULT; AGED; ARTICLE; CLINICAL ASSESSMENT; FEMALE; FOLLOW UP; HUMAN; JOINT RADIOGRAPHY; MAJOR CLINICAL STUDY; MALE; MORTALITY; MULTICENTER STUDY; ORTHOPEDIC SURGERY; PRIORITY JOURNAL; PROGNOSIS; REMISSION; RHEUMATOID ARTHRITIS; TREATMENT OUTCOME; X RAY;

ADULT; AGED; ANTIRHEUMATIC AGENTS; ARTHRITIS, RHEUMATOID; DISEASE PROGRESSION; DRUG THERAPY, COMBINATION; EPIDEMIOLOGIC METHODS; FEMALE; GLUCOCORTICOIDS; HUMANS; MALE; MIDDLE AGED; PAIN; PROGNOSIS; REMISSION INDUCTION; SEX FACTORS; TIME FACTORS; TREATMENT OUTCOME;

EID: 84855166600     PISSN: 14620324     EISSN: 14620332     Source Type: Journal    
DOI: 10.1093/rheumatology/ker250     Document Type: Article

References (33)

1. Fex E, Jonsson K, Johnson U, Eberhardt K. Development of radiographic damage during the first 5-6 yr of rheumatoid arthritis. A prospective follow-up study of a Swedish cohort. Br J Rheumatol 1996;35:1106-15.
2. Capell HA, Murphy EA, Hunter JA. Rheumatoid arthritis: workload and outcome over 10 years. Q J Med 1991;79: 461-76.
3. Young A, Dixey J, Cox N et al. How does functional disability in early rheumatoid arthritis (RA) affect patients and their lives? Results of 5 years of follow-up in 732 patients from the early RA study (ERAS). Rheumatology 2000;39: 603-11.
4. James D, Young A, Kulinskaya E et al. Orthopaedic intervention in early rheumatoid arthritis: occurrence and predictive factors in an inception cohort of 1064 patients followed for 5 years. Rheumatology 2004;43:369-76.
5. Wolfe F, Mitchell DM, Sibley JT et al. The mortality of rheumatoid arthritis. Arthritis Rheum 1994;37:481-94.
6. Mottonen T, Hannonen P, Korpela M et al. Delay to institution of therapy and induction of remission using single-drug or combination-disease modifying antirheumatic drug therapy in early rheumatoid arthritis. Arthritis Rheum 2002;46:894-8.
7. Shaver TS, Anderson JD, Weidensaul DN et al. The problem of rheumatoid arthritis disease activity and remission in clinical practice. J Rheumatol 2008;35: 1015-22.
8. van der Helm-van Mil AH, Breedveld FC, Huizinga TW. Aspects of early arthritis. Definition of disease states in early arthritis: remission versus minimal disease activity. Arthritis Res Ther 2006;8:216.
9. van der Heijde D, van't Hof MA, van Riel PL et al. Judging disease activity in clinical practice in rheumatoid arthritis: first step in the development of a disease activity score. Ann Rheum Dis 1990;49:916-20.
10. van der Woude D, Young A, Jayakumar K et al. Prevalence and predictive factors for sustained disease-modifying antirheumatic drug-free remission in rheumatoid arthritis: results from two large early arthritis cohorts. Arthritis Rheum 2009;60:2262-71.
11. ERAS Study Group. Socioeconomic deprivation and rheumatoid disease: what lessons for the health service? Ann Rheum Dis 2000;59:794-9.
12. Mattey DL, Thomson W, Ollier WER et al. Association of DRB1 shared epitope genotypes with early mortality in rheumatoid arthritis: results of eighteen years of follow up from the early rheumatoid arthritis study. Arthritis Rheum 2007;56:1408-16.
13. Young A, Dixey J, Kulinskaya E et al. Which patients stop working because of rheumatoid arthritis? Results of five years' follow up in 732 patients from the early RA study (ERAS). Ann Rheum Dis 2002;61:335-40.
14. Dixey J, Solymossy C, Young A, Early RA. Study. Is it possible to predict radiological damage in early rheumatoid arthritis (RA)? A report on occurrence, progression, and prognostic factors for radiological erosions over first 3 years in 866 patients from the Early RA Study (ERAS). J Rheumatol 2004;31(Suppl. 69):48-54.
15. Young A, Koduri G, Batley M et al. Mortality in rheumatoid arthritis. Increased in the early course of disease, in ischaemic heart disease and in pulmonary fibrosis. Rheumatology 2007;46:350-7.
16. Prevoo MLL, van Gestel AM, van Thof MA, van Rijswijk MH, van de Putte LBA, van Riel PLCM. Remission in a prospective study of patients with rheumatoid arthritis. American Rheumatism Association preliminary remission criteria in relation to the Disease Activity Score. Br J Rheumatol 1996;35:1101-5.
17. Fransen J, Creemers MCW, van Riel PLCM. Remission in rheumatoid arthritis: agreement of the disease activity score (DAS28) with the ARA preliminary remission criteria. Rheumatology 2004;43:1252-5.
18. van Gestel AM, Prevoo MLL, van't Hof MA, van Rijswijk MH, van de Putte LBA, van Riel PLCM. Development and validation of the European League Against Rheumatism response criteria for rheumatoid arthritis: comparison with the preliminary American College of Rheumatology and the World Health Organization/International League Against Rheumatism criteria. Arthritis Rheum 1996;39:34-40.
19. Solymossy C, Dixey J, Utley M et al. Larsen scoring of digitized X-ray images. Rheumatology 1999;38:1127-9.
20. Arnett FC, Edworthy SM, Bloch DA et al. The American Rheumatism Association1987 revised criteria for the classification of rheumatoid arthritis. Arthritis Rheum 1988; 31:315-24.
21. Prevoo MLL, van't Hof MA, Kuper HH, van Leeuwen MA, van de Putte LBA, van Riel PLCM. Modified disease activity scores that include twenty-eight-joint counts. Development and validation in a prospective longitudinal study of patients with rheumatoid arthritis. Arthritis Rheum 1995;38:44-8.
22. Mottonen T, Paimela L, Ahonen J, Helve T, Hannon P, Leirisalo-Repo M. Outcome in patients with early rheumatoid arthritis treated according to the 'sawtooth' strategy. Arthritis Rheum 1996;39:996-1005.
23. Eberhardt K, Fex E. Clinical course and remission rate in patients with early rheumatoid arthritis: relationship to outcome after 5 years. Br J Rheumatol 1998;37:1324-9.
24. Makinen H, Kautiainen H, Hannonen P, Sokka T. Frequency of remissions in early rheumatoid arthritis defined by 3 sets of criteria. A 5-year follow up study. J Rheumatol 2005;32:796-800.
25. Gossec L, Dougados M, Goupille P et al. Prognostic factors for remission in early rheumatoid arthritis: a multiparameter prospective study. Ann Rheum Dis 2004; 63:675-80.
26. Pinals RS, Masi AT, Larsen RA. Preliminary criteria for clinical remission in RA. Arthritis Rheum 1981;24:1308-15.
27. Forslind K, Hafstrom I, Ahlmen M, Svensson B. for the BARFOT Study Group. Sex: a major predictor of remission in early rheumatoid arthritis? Ann Rheum Dis 2007;66: 46-52.
28. Makinen H, Hannonen P, Sokka T. Sex: a major predictor of remission as measured by 28-joint Disease Activity Score (DAS28) in early rheumatoid arthritis? Ann Rheum Dis 2008;67:1052-3.
29. Lard LR, Visser H, Speyer I et al. Early versus delayed treatment in patients with recent-onset rheumatoid arthritis: comparison of two cohorts who received different treatment strategies. Am J Med 2001;111:446-51.
30. Kiely P, Williams R, Walsh D, Young A. Contemporary patterns of care and disease activity outcome in early rheumatoid arthritis: the ERAN cohort. Rheumatology 2009;48:57-60.
31. Molenaar ETH, Voskuyl AE, Dijkmans BAC. Functional disability in relation to radiological damage and disease activity in patients with rheumatoid arthritis in remission. J Rheumatol 2002;29:267-70.
32. Molenaar ETH, Voskuyl AE, Dinant HJ, Bezemer PD, Boers M, Dijkmans BAC. Progression of radiologic damage in patients with rheumatoid arthritis in clinical remission. Arthritis Rheum 2004;50:36-42.
33. Aletaha D, Funovits J, Breedveld FC, Sharp J, Segurado O, Smolen JS. Rheumatoid arthritis joint progression in sustained remission is determined by disease activity levels preceding the period of radiographic assessment. Arthritis Rheum 2009;60: 1242-9.