메뉴 건너뛰기




Volumn 71, Issue 11, 2012, Pages 1820-1826

Drug retention rates and relevant risk factors for drug discontinuation due to adverse events in rheumatoid arthritis patients receiving anticytokine therapy with different target molecules

(28)  Sakai, Ryoko a   Tanaka, Michi a   Nanki, Toshihiro a   Watanabe, Kaori a   Yamazaki, Hayato a   Koike, Ryuji a,b   Nagasawa, Hayato c   Amano, Koichi c   Saito, Kazuyoshi d   Tanaka, Yoshiya d   Ito, Satoshi e   Sumida, Takayuki e   Ihata, Atsushi f   Ishigatsubo, Yoshiaki f   Atsumi, Tatsuya g   Koike, Takao g   Nakajima, Atsuo h   Tamura, Naoto i   Fujii, Takao j   Dobashi, Hiroaki k   more..


Author keywords

[No Author keywords available]

Indexed keywords

C REACTIVE PROTEIN; CORTICOSTEROID; CYCLOSPORIN A; DISEASE MODIFYING ANTIRHEUMATIC DRUG; ETANERCEPT; IMMUNOSUPPRESSIVE AGENT; INFLIXIMAB; LEFLUNOMIDE; METHOTREXATE; MIZORIBINE; PREDNISOLONE; TACROLIMUS; TOCILIZUMAB;

EID: 84867405325     PISSN: 00034967     EISSN: 14682060     Source Type: Journal    
DOI: 10.1136/annrheumdis-2011-200838     Document Type: Article
Times cited : (49)

References (50)
  • 2
    • 77953718691 scopus 로고    scopus 로고
    • Current evidence for a strategic approach to the management of rheumatoid arthritis with disease-modifying antirheumatic drugs: A systematic literature review informing the EULAR recommendations for the management of rheumatoid arthritis
    • Knevel R, Schoels M, Huizinga TW, et al. Current evidence for a strategic approach to the management of rheumatoid arthritis with disease-modifying antirheumatic drugs: a systematic literature review informing the EULAR recommendations for the management of rheumatoid arthritis. Ann Rheum Dis 2010;69:987-94.
    • (2010) Ann Rheum Dis , vol.69 , pp. 987-994
    • Knevel, R.1    Schoels, M.2    Huizinga, T.W.3
  • 3
    • 37449017748 scopus 로고    scopus 로고
    • Update on the Japanese guidelines for the use of infliximab and etanercept in rheumatoid arthritis
    • Koike R, Takeuchi T, Eguchi K, et al. Update on the Japanese guidelines for the use of infliximab and etanercept in rheumatoid arthritis. Mod Rheumatol 2007;17:451-8.
    • (2007) Mod Rheumatol , vol.17 , pp. 451-458
    • Koike, R.1    Takeuchi, T.2    Eguchi, K.3
  • 4
    • 68549105886 scopus 로고    scopus 로고
    • Japan College of Rheumatology 2009 guidelines for the use of tocilizumab, a humanized anti-interleukin-6 receptor monoclonal antibody, in rheumatoid arthritis
    • Koike R, Harigai M, Atsumi T, et al. Japan College of Rheumatology 2009 guidelines for the use of tocilizumab, a humanized anti-interleukin-6 receptor monoclonal antibody, in rheumatoid arthritis. Mod Rheumatol 2009;19:351-7.
    • (2009) Mod Rheumatol , vol.19 , pp. 351-357
    • Koike, R.1    Harigai, M.2    Atsumi, T.3
  • 5
    • 67449102437 scopus 로고    scopus 로고
    • Postmarketing surveillance of the safety and effectiveness of etanercept in Japan
    • Koike T, Harigai M, Inokuma S, et al. Postmarketing surveillance of the safety and effectiveness of etanercept in Japan. J Rheumatol 2009;36:898-906.
    • (2009) J Rheumatol , vol.36 , pp. 898-906
    • Koike, T.1    Harigai, M.2    Inokuma, S.3
  • 6
    • 41849132452 scopus 로고    scopus 로고
    • Retrospective clinical study on the notable efficacy and related factors of infliximab therapy in a rheumatoid arthritis management group in Japan: One-year clinical outcomes (RECONFIRM-2)
    • Tanaka Y, Takeuchi T, Inoue E, et al. Retrospective clinical study on the notable efficacy and related factors of infliximab therapy in a rheumatoid arthritis management group in Japan: one-year clinical outcomes (RECONFIRM-2). Mod Rheumatol 2008;18:146-52.
    • (2008) Mod Rheumatol , vol.18 , pp. 146-152
    • Tanaka, Y.1    Takeuchi, T.2    Inoue, E.3
  • 7
    • 79960128977 scopus 로고    scopus 로고
    • Efficacy and tolerability of tocilizumab in rheumatoid arthritis patients seen in daily clinical practice in Japan: Results from a retrospective study (REACTION study)
    • Yamanaka H, Tanaka Y, Inoue E, et al. Efficacy and tolerability of tocilizumab in rheumatoid arthritis patients seen in daily clinical practice in Japan: results from a retrospective study (REACTION study). Mod Rheumatol 2011;21:122-33.
    • (2011) Mod Rheumatol , vol.21 , pp. 122-133
    • Yamanaka, H.1    Tanaka, Y.2    Inoue, E.3
  • 9
    • 77953696525 scopus 로고    scopus 로고
    • EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatic drugs
    • Smolen JS, Landewé R, Breedveld FC, et al. EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatic drugs. Ann Rheum Dis 2010;69:964-75.
    • (2010) Ann Rheum Dis , vol.69 , pp. 964-975
    • Smolen, J.S.1    Landewé, R.2    Breedveld, F.C.3
  • 10
    • 77954973766 scopus 로고    scopus 로고
    • Discontinuation of infliximab after attaining low disease activity in patients with rheumatoid arthritis: RRR (remission induction by Remicade in RA) study
    • Tanaka Y, Takeuchi T, Mimori T, et al. Discontinuation of infliximab after attaining low disease activity in patients with rheumatoid arthritis: RRR (remission induction by Remicade in RA) study. Ann Rheum Dis 2010;69:1286-91.
    • (2010) Ann Rheum Dis , vol.69 , pp. 1286-1291
    • Tanaka, Y.1    Takeuchi, T.2    Mimori, T.3
  • 11
    • 78751703180 scopus 로고    scopus 로고
    • Discontinuing treatment in patients with rheumatoid arthritis in sustained clinical remission: Exploratory analyses from the BeSt study
    • Klarenbeek NB, van der Kooij SM, Güler-Yüksel M, et al. Discontinuing treatment in patients with rheumatoid arthritis in sustained clinical remission: exploratory analyses from the BeSt study. Ann Rheum Dis 2011;70:315-9.
    • (2011) Ann Rheum Dis , vol.70 , pp. 315-319
    • Klarenbeek, N.B.1    Van Der Kooij, S.M.2    Güler-Yüksel, M.3
  • 12
    • 84870322518 scopus 로고    scopus 로고
    • Discontinuation of adalimumab treatment in rheumatoid arthritis patients after achieving low disease activity
    • Published Online First: 20 January doi:10.1007/s10165-011-0586-5
    • Harigai M, Takeuchi T, Tanaka Y, et al. Discontinuation of adalimumab treatment in rheumatoid arthritis patients after achieving low disease activity. Mod Rheumatol Published Online First: 20 January 2012. doi:10.1007/s10165-011- 0586-5.
    • (2012) Mod Rheumatol
    • Harigai, M.1    Takeuchi, T.2    Tanaka, Y.3
  • 13
    • 77951875709 scopus 로고    scopus 로고
    • Seven-year follow-up of infliximab therapy in rheumatoid arthritis patients with severe long-standing refractory disease: Attrition rate and evolution of disease activity
    • Vander Cruyssen B, Durez P, Westhovens R, et al. Seven-year follow-up of infliximab therapy in rheumatoid arthritis patients with severe long-standing refractory disease: attrition rate and evolution of disease activity. Arthritis Res Ther 2010;12:R77.
    • (2010) Arthritis Res Ther , vol.12
    • Vander Cruyssen, B.1    Durez, P.2    Westhovens, R.3
  • 14
    • 66249124273 scopus 로고    scopus 로고
    • Comparison of drug retention rates and causes of drug discontinuation between anti-tumor necrosis factor agents in rheumatoid arthritis
    • Du Pan SM, Dehler S, Ciurea A, et al. Comparison of drug retention rates and causes of drug discontinuation between anti-tumor necrosis factor agents in rheumatoid arthritis. Arthritis Rheum 2009;61:560-8.
    • (2009) Arthritis Rheum , vol.61 , pp. 560-568
    • Du Pan, S.M.1    Dehler, S.2    Ciurea, A.3
  • 15
    • 70349402169 scopus 로고    scopus 로고
    • Long-term safety and efficacy of tocilizumab, an anti-IL-6 receptor monoclonal antibody, in monotherapy, in patients with rheumatoid arthritis (the STREAM study): Evidence of safety and efficacy in a 5-year extension study
    • Nishimoto N, Miyasaka N, Yamamoto K, et al. Long-term safety and efficacy of tocilizumab, an anti-IL-6 receptor monoclonal antibody, in monotherapy, in patients with rheumatoid arthritis (the STREAM study): evidence of safety and efficacy in a 5-year extension study. Ann Rheum Dis 2009;68:1580-4.
    • (2009) Ann Rheum Dis , vol.68 , pp. 1580-1584
    • Nishimoto, N.1    Miyasaka, N.2    Yamamoto, K.3
  • 16
    • 70049109275 scopus 로고    scopus 로고
    • TNF-alpha antagonist survival rate in a cohort of rheumatoid arthritis patients observed under conditions of standard clinical practice
    • Marchesoni A, Zaccara E, Gorla R, et al. TNF-alpha antagonist survival rate in a cohort of rheumatoid arthritis patients observed under conditions of standard clinical practice. Ann NY Acad Sci 2009;1173:837-46.
    • (2009) Ann NY Acad Sci , vol.1173 , pp. 837-846
    • Marchesoni, A.1    Zaccara, E.2    Gorla, R.3
  • 17
    • 74849094402 scopus 로고    scopus 로고
    • Direct comparison of treatment responses, remission rates, and drug adherence in patients with rheumatoid arthritis treated with adalimumab, etanercept, or infliximab: Results from eight years of surveillance of clinical practice in the nationwide Danish DANBIO registry
    • Hetland ML, Christensen IJ, Tarp U, et al. Direct comparison of treatment responses, remission rates, and drug adherence in patients with rheumatoid arthritis treated with adalimumab, etanercept, or infliximab: results from eight years of surveillance of clinical practice in the nationwide Danish DANBIO registry. Arthritis Rheum 2010;62:22-32.
    • (2010) Arthritis Rheum , vol.62 , pp. 22-32
    • Hetland, M.L.1    Christensen, I.J.2    Tarp, U.3
  • 18
    • 36749002002 scopus 로고    scopus 로고
    • Impact of concomitant DMARD therapy on adherence to treatment with etanercept and infliximab in rheumatoid arthritis. Results from a six-year observational study in southern Sweden
    • Kristensen LE, Saxne T, Nilsson JA, et al. Impact of concomitant DMARD therapy on adherence to treatment with etanercept and infliximab in rheumatoid arthritis. Results from a six-year observational study in southern Sweden. Arthritis Res Ther 2006;8:R174.
    • (2006) Arthritis Res Ther , vol.8
    • Kristensen, L.E.1    Saxne, T.2    Nilsson, J.A.3
  • 19
    • 79551658174 scopus 로고    scopus 로고
    • Treatment response, drug survival, and predictors thereof in 764 patients with psoriatic arthritis treated with anti-tumor necrosis factor a therapy: Results from the nationwide Danish DANBIO registry
    • Glintborg B, Østergaard M, Dreyer L, et al. Treatment response, drug survival, and predictors thereof in 764 patients with psoriatic arthritis treated with anti-tumor necrosis factor a therapy: results from the nationwide Danish DANBIO registry. Arthritis Rheum 2011;63:382-90.
    • (2011) Arthritis Rheum , vol.63 , pp. 382-390
    • Glintborg, B.1    Østergaard, M.2    Dreyer, L.3
  • 20
    • 79952359578 scopus 로고    scopus 로고
    • Impact of concomitant use of DMARDs on the persistence with anti-TNF therapies in patients with rheumatoid arthritis: Results from the British Society for Rheumatology Biologics Register
    • Soliman MM, Ashcroft DM, Watson KD, et al. Impact of concomitant use of DMARDs on the persistence with anti-TNF therapies in patients with rheumatoid arthritis: results from the British Society for Rheumatology Biologics Register. Ann Rheum Dis 2011;70:583-9.
    • (2011) Ann Rheum Dis , vol.70 , pp. 583-589
    • Soliman, M.M.1    Ashcroft, D.M.2    Watson, K.D.3
  • 22
    • 33846090262 scopus 로고    scopus 로고
    • Retention rates of tumor necrosis factor blockers in daily practice in 770 rheumatic patients
    • Duclos M, Gossec L, Ruyssen-Witrand A, et al. Retention rates of tumor necrosis factor blockers in daily practice in 770 rheumatic patients. J Rheumatol 2006;33:2433-8.
    • (2006) J Rheumatol , vol.33 , pp. 2433-2438
    • Duclos, M.1    Gossec, L.2    Ruyssen-Witrand, A.3
  • 23
    • 83255188765 scopus 로고    scopus 로고
    • Postmarketing surveillance of safety and effectiveness of etanercept in Japanese patients with rheumatoid arthritis
    • Koike T, Harigai M, Inokuma S, et al. Postmarketing surveillance of safety and effectiveness of etanercept in Japanese patients with rheumatoid arthritis. Mod Rheumatol 2011;21:343-51.
    • (2011) Mod Rheumatol , vol.21 , pp. 343-351
    • Koike, T.1    Harigai, M.2    Inokuma, S.3
  • 24
    • 79951689117 scopus 로고    scopus 로고
    • Long-term effectiveness and safety of TNF-blocking agents in daily clinical practice: Results from the Dutch Rheumatoid Arthritis Monitoring register
    • Kievit W, Fransen J, Adang EM, et al. Long-term effectiveness and safety of TNF-blocking agents in daily clinical practice: results from the Dutch Rheumatoid Arthritis Monitoring register. Rheumatology (Oxford) 2011;50:196-203.
    • (2011) Rheumatology (Oxford) , vol.50 , pp. 196-203
    • Kievit, W.1    Fransen, J.2    Adang, E.M.3
  • 25
    • 79957630321 scopus 로고    scopus 로고
    • Efficacy of abatacept and tocilizumab in patients with rheumatoid arthritis treated in clinical practice: Results from the nationwide Danish DANBIO registry
    • Leffers HC, Ostergaard M, Glintborg B, et al. Efficacy of abatacept and tocilizumab in patients with rheumatoid arthritis treated in clinical practice: results from the nationwide Danish DANBIO registry. Ann Rheum Dis 2011;70:1216-22.
    • (2011) Ann Rheum Dis , vol.70 , pp. 1216-1222
    • Leffers, H.C.1    Ostergaard, M.2    Glintborg, B.3
  • 27
    • 84862563304 scopus 로고    scopus 로고
    • A comparative effectiveness study of adalimumab, etanercept and infliximab in biologically naive and switched rheumatoid arthritis patients: Results from the US CORRONA registry
    • Published Online First: 30 January doi:10.1136/annrheymdis-2011-150573
    • Greenberg JD, Reed G, Decktor D, et al. A comparative effectiveness study of adalimumab, etanercept and infliximab in biologically naive and switched rheumatoid arthritis patients: results from the US CORRONA registry. Ann Rheum Dis Published Online First: 30 January 2012. doi:10.1136/annrheymdis-2011- 150573.
    • (2012) Ann Rheum Dis
    • Greenberg, J.D.1    Reed, G.2    Decktor, D.3
  • 28
    • 83255162444 scopus 로고    scopus 로고
    • The REAL database reveals no significant risk of serious infection during treatment with a methotrexate dose of more than 8 mg/week in patients with rheumatoid arthritis
    • Sakai R, Komano Y, Tanaka M, et al. The REAL database reveals no significant risk of serious infection during treatment with a methotrexate dose of more than 8 mg/week in patients with rheumatoid arthritis. Mod Rheumatol 2011;21:444-8.
    • (2011) Mod Rheumatol , vol.21 , pp. 444-448
    • Sakai, R.1    Komano, Y.2    Tanaka, M.3
  • 29
    • 79959994678 scopus 로고    scopus 로고
    • Incidence and risk factors for serious infection in patients with rheumatoid arthritis treated with tumor necrosis factor inhibitors: A report from the Registry of Japanese Rheumatoid Arthritis Patients for Longterm Safety
    • Komano Y, Tanaka M, Nanki T, et al. Incidence and risk factors for serious infection in patients with rheumatoid arthritis treated with tumor necrosis factor inhibitors: a report from the Registry of Japanese Rheumatoid Arthritis Patients for Longterm Safety. J Rheumatol 2011;38:1258-64.
    • (2011) J Rheumatol , vol.38 , pp. 1258-1264
    • Komano, Y.1    Tanaka, M.2    Nanki, T.3
  • 30
    • 72649098710 scopus 로고
    • Therapeutic criteria in rheumatoid arthritis
    • Steinbrocker O, Traeger CH, Batterman RC. Therapeutic criteria in rheumatoid arthritis. JAMA 1949;140:659-62.
    • (1949) JAMA , vol.140 , pp. 659-662
    • Steinbrocker, O.1    Traeger, C.H.2    Batterman, R.C.3
  • 31
    • 0348019017 scopus 로고    scopus 로고
    • The Stanford Health Assessment Questionnaire: Dimensions and practical applications
    • Bruce B, Fries JF. The Stanford Health Assessment Questionnaire: dimensions and practical applications. Health Qual Life Outcomes 2003;1:20.
    • (2003) Health Qual Life Outcomes , vol.1 , pp. 20
    • Bruce, B.1    Fries, J.F.2
  • 32
    • 35548966748 scopus 로고    scopus 로고
    • Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) statement: Guidelines for reporting observational studies
    • von Elm E, Altman DG, Egger M, et al. Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) statement: guidelines for reporting observational studies. BMJ 2007;335:806-8.
    • (2007) BMJ , vol.335 , pp. 806-808
    • Von Elm, E.1    Altman, D.G.2    Egger, M.3
  • 33
    • 67449088331 scopus 로고    scopus 로고
    • Changing patterns of tumor necrosis factor inhibitor use in 9074 patients with rheumatoid arthritis
    • Yazici Y, Krasnokutsky S, Barnes JP, et al. Changing patterns of tumor necrosis factor inhibitor use in 9074 patients with rheumatoid arthritis. J Rheumatol 2009;36:907-13.
    • (2009) J Rheumatol , vol.36 , pp. 907-913
    • Yazici, Y.1    Krasnokutsky, S.2    Barnes, J.P.3
  • 34
    • 34848916744 scopus 로고    scopus 로고
    • Assessment of adherence to and persistence on disease-modifying antirheumatic drugs (DMARDs) in patients with rheumatoid arthritis
    • Grijalva CG, Chung CP, Arbogast PG, et al. Assessment of adherence to and persistence on disease-modifying antirheumatic drugs (DMARDs) in patients with rheumatoid arthritis. Med Care 2007;45(10 Suppl 2):S66-76.
    • (2007) Med Care , vol.45 , Issue.10 SUPPL. 2
    • Grijalva, C.G.1    Chung, C.P.2    Arbogast, P.G.3
  • 35
    • 70450202574 scopus 로고    scopus 로고
    • The reason for discontinuation of the first tumor necrosis factor (TNF) blocking agent does not influence the effect of a second TNF blocking agent in patients with rheumatoid arthritis
    • Blom M, Kievit W, Fransen J, et al. The reason for discontinuation of the first tumor necrosis factor (TNF) blocking agent does not influence the effect of a second TNF blocking agent in patients with rheumatoid arthritis. J Rheumatol 2009;36:2171-7.
    • (2009) J Rheumatol , vol.36 , pp. 2171-2177
    • Blom, M.1    Kievit, W.2    Fransen, J.3
  • 36
    • 19944431840 scopus 로고    scopus 로고
    • Very early treatment with infliximab in addition to methotrexate in early, poor-prognosis rheumatoid arthritis reduces magnetic resonance imaging evidence of synovitis and damage, with sustained benefit after infliximab withdrawal: Results from a twelve-month randomized, double-blind, placebo-controlled trial
    • DOI 10.1002/art.20712
    • Quinn MA, Conaghan PG, O'Connor PJ, et al. Very early treatment with infliximab in addition to methotrexate in early, poor-prognosis rheumatoid arthritis reduces magnetic resonance imaging evidence of synovitis and damage, with sustained benefit after infliximab withdrawal: results from a twelve-month randomized, double-blind, placebo-controlled trial. Arthritis Rheum 2005;52:27-35. (Pubitemid 40129229)
    • (2005) Arthritis and Rheumatism , vol.52 , Issue.1 , pp. 27-35
    • Quinn, M.A.1    Conaghan, P.G.2    O'Connor, P.J.3    Karim, Z.4    Greenstein, A.5    Brown, A.6    Brown, C.7    Fraser, A.8    Jarret, S.9    Emery, P.10
  • 38
    • 42949168291 scopus 로고    scopus 로고
    • Clinical and radiographic outcomes of four different treatment strategies in patients with early rheumatoid arthritis (the BeSt study): A randomized, controlled trial
    • Goekoop-Ruiterman YP, de Vries-Bouwstra JK, Allaart CF, et al. Clinical and radiographic outcomes of four different treatment strategies in patients with early rheumatoid arthritis (the BeSt study): a randomized, controlled trial. Arthritis Rheum 2008;58(2 Suppl):S126-35.
    • (2008) Arthritis Rheum , vol.58 , Issue.2 SUPPL.
    • Goekoop-Ruiterman, Y.P.1    De Vries-Bouwstra, J.K.2    Allaart, C.F.3
  • 40
    • 67449133540 scopus 로고    scopus 로고
    • Drug-free remission, functioning and radiographic damage after 4 years of response-driven treatment in patients with recent-onset rheumatoid arthritis
    • van der Kooij SM, Goekoop-Ruiterman YP, de Vries-Bouwstra JK, et al. Drug-free remission, functioning and radiographic damage after 4 years of response-driven treatment in patients with recent-onset rheumatoid arthritis. Ann Rheum Dis 2009;68:914-21.
    • (2009) Ann Rheum Dis , vol.68 , pp. 914-921
    • Van Der Kooij, S.M.1    Goekoop-Ruiterman, Y.P.2    De Vries-Bouwstra, J.K.3
  • 41
    • 84867400144 scopus 로고    scopus 로고
    • Drug Free REmission after Cessation of Tocilizumab (Actemra) Monotherapy (DREAM Study)
    • Nishimoto N. Drug Free REmission After Cessation Of Tocilizumab (Actemra) Monotherapy (DREAM Study). Arthritis Rheum 2010;62:S750.
    • (2010) Arthritis Rheum , vol.62
    • Nishimoto, N.1
  • 43
    • 33644931095 scopus 로고    scopus 로고
    • Development of antiinfliximab antibodies and relationship to clinical response in patients with rheumatoid arthritis
    • Wolbink GJ, Vis M, Lems W, et al. Development of antiinfliximab antibodies and relationship to clinical response in patients with rheumatoid arthritis. Arthritis Rheum 2006;54:711-15.
    • (2006) Arthritis Rheum , vol.54 , pp. 711-715
    • Wolbink, G.J.1    Vis, M.2    Lems, W.3
  • 45
    • 77952746394 scopus 로고    scopus 로고
    • Pharmacology of TNF blockade in rheumatoid arthritis and other chronic inflammatory diseases
    • Taylor PC. Pharmacology of TNF blockade in rheumatoid arthritis and other chronic inflammatory diseases. Curr Opin Pharmacol 2010;10:308-15.
    • (2010) Curr Opin Pharmacol , vol.10 , pp. 308-315
    • Taylor, P.C.1
  • 47
    • 78349285989 scopus 로고    scopus 로고
    • Clinical evaluation of tocilizumab for patients with active rheumatoid arthritis refractory to anti-TNF biologics: Tocilizumab in combination with methotrexate
    • Nakashima Y, Kondo M, Harada H, et al. Clinical evaluation of tocilizumab for patients with active rheumatoid arthritis refractory to anti-TNF biologics: tocilizumab in combination with methotrexate. Mod Rheumatol 2010;20:343-52.
    • (2010) Mod Rheumatol , vol.20 , pp. 343-352
    • Nakashima, Y.1    Kondo, M.2    Harada, H.3
  • 48
    • 79953319576 scopus 로고    scopus 로고
    • Effectiveness and safety of the interleukin 6-receptor antagonist tocilizumab after 4 and 24 weeks in patients with active rheumatoid arthritis: The first phase IIIb real-life study (TAMARA)
    • Burmester GR, Feist E, Kellner H, et al. Effectiveness and safety of the interleukin 6-receptor antagonist tocilizumab after 4 and 24 weeks in patients with active rheumatoid arthritis: the first phase IIIb real-life study (TAMARA). Ann Rheum Dis 2011;70:755-9.
    • (2011) Ann Rheum Dis , vol.70 , pp. 755-759
    • Burmester, G.R.1    Feist, E.2    Kellner, H.3
  • 49
    • 58749090375 scopus 로고    scopus 로고
    • Serious infections during anti-TNFalpha treatment in rheumatoid arthritis patients
    • Favalli EG, Desiati F, Atzeni F, et al. Serious infections during anti-TNFalpha treatment in rheumatoid arthritis patients. Autoimmun Rev 2009;8:266-73.
    • (2009) Autoimmun Rev , vol.8 , pp. 266-273
    • Favalli, E.G.1    Desiati, F.2    Atzeni, F.3
  • 50
    • 79953314434 scopus 로고    scopus 로고
    • High disease activity is associated with an increased risk of infection in patients with rheumatoid arthritis
    • Au K, Reed G, Curtis JR, et al. High disease activity is associated with an increased risk of infection in patients with rheumatoid arthritis. Ann Rheum Dis 2011;70:785-91.
    • (2011) Ann Rheum Dis , vol.70 , pp. 785-791
    • Au, K.1    Reed, G.2    Curtis, J.R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.