Reply to Is progesterone a neutral or protective factor for breast cancer?

Nature Reviews Cancer

Volumn 14, Issue 2, 2014, Pages 146-

  Brisken, Cathrin ^a  

^a EPFL   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMALS; BREAST NEOPLASMS; FEMALE; HUMANS; PROGESTERONE;

EID: 84894555847     PISSN: 1474175X     EISSN: 14741768     Source Type: Journal    
DOI: 10.1038/nrc3518-c2     Document Type: Letter

References (8)

1. Brisken, C. Progesterone signalling in breast cancer: a neglected hormone coming into the limelight. Nature Rev. Cancer 13, 385-396 (2013).
2. Muti, P. Is progesterone a neutral or protective factor for breast cancer? Nature Rev. Cancer http://dx.doi.org/10.1038/nrc3518-c1 (2014).
3. Schernhammer, E. S. et al. Endogenous sex steroids in premenopausal women and risk of breast cancer: the ORDET cohort. Breast Cancer Res. 15, R46 (2013).
4. Foidart, J. M. et al. Estradiol and progesterone regulate the proliferation of human breast epithelial cells. Fertil. Steril. 69, 963-969 (1998).
5. Alkhalaf, M., El-Mowafy, A. & Karam, S. Growth inhibition of MCF-7 human breast cancer cells by progesterone is associated with cell differentiation and phosphorylation of Akt protein. Eur. J. Cancer Prev. 11, 481-488 (2002).
6. Alkhalaf, M. & El-Mowafy, A. M. Overexpression of wild-type p53 gene renders MCF-7 breast cancer cells more sensitive to the antiproliferative effect of progesterone. J. Endocrinol. 179, 55-62 (2003).
7. Lin, V. C., Eng, A. S., Hen, N. E., Ng, E. H. & Chowdhury, S. H. Effect of progesterone on the invasive properties and tumor growth of progesterone receptor-transfected breast cancer cells MDA-MB-231. Clin. Cancer Res. 7, 2880-2886 (2001).
8. MacMahon, B. et al. Age at first birth and breast cancer risk. Bull. World Health Organ. 43, 209-221 (1970).