Msx2 plays a critical role in lens epithelium cell cycle control

International Journal of Ophthalmology

Volumn 6, Issue 3, 2013, Pages 276-279

  Zhao, Jiang Yue ^a   Zhuang, Feng Feng ^b   Wang, Hong Yan ^c   Wu, Di ^a   Zhang, Jin Song ^a  

^a CHINA MEDICAL UNIVERSITY   (China)

^b UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^c Maternity and Child Healthcare Hospital of Liaoning Province   (China)

Author keywords

Cell cycle; Lens epithelium cell; Msx2

Indexed keywords

EID: 84894546878     PISSN: 22223959     EISSN: 22274898     Source Type: Journal    
DOI: 10.3980/j.issn.2222-3959.2013.03.04     Document Type: Article

References (23)

1. White TW, Gao Y, Li L., Sellitto C, Srinivas M. Optimal lens epithelial cell proliferation is dependent on the connexin isoform providing gap junctional coupling. Invest Ophthalmol Vis Sci. 2007; 48(12): 5630-5637.
2. Menko AS. Lens epithelial cell differentiation. Exp Eye Res. 2002; 75(5): 485-490.
3. Piatigorsky J. Lens differentiation in vertebrates: a review of cellular and molecular features. Differentiation. 1981; 19(3): 134-153.
4. Donner AL, Lachke SA, Maas RL. Lens induction in vertebrates: variations on a conserved theme of signaling events. Semin Cell Dev Biol. 2006; 17(6): 676-685.
5. Cvekl A, Duncan MK. Genetic and epigenetic mechanisms of gene regulation during lens development. Prog Retin Eye Res. 2007; 26(6): 555-597.
6. Wawersik S, Purcell P, Rauchman M., Dudley AT, Robertson EJ, Maas R. BMP7 acts in murine lens placode development. Dev Biol. 1999; 207(1): 176-188.
7. Belecky-Adams T.L., Adler R, Beebe DC. Bone morphogenetic protein signaling and the initiation of lens fiber cell differentiation. Development. 2002; 129(16): 3795-3802.
8. Grogg MW, Call MK, Okamoto M, Vergara M.N., Del Rio-Tsonis K, Tsonis PA. BMP inhibition-driven regulation of six-3 underlies induction of newt lens regeneration. Nature. 2005; 438(7069): 858-862.
9. Haynes T, Gutierrez C, Aycinena J.C., Tsonis PA, Del Rio-Tsonis K. BMP signaling mediates stem/progenitor cell-induced retina regeneration. Proc Natl Acad Sci USA. 2007; 104(51): 20380-20385.
10. Zhao J, Kawai K, Wang H., Wu D, Wang M, Yue Z., Zhang J, Liu YH. Loss of Msx2 function down-regulates the FoxE3 expression and results in anterior segment dysgenesis resembling peters anomaly. Am J Pathol. 2012; 180(6): 2230-2239.
11. Liu YH, Kundu R, Wu L., Luo W, Ignelzi MA, Jr, Snead ML, Maxson RE., Jr Premature suture closure and ectopic cranial bone in mice expressing Msx2 transgenes in the developing skull. Proc Natl Acad Sci USA. 1995; 92(13): 6137-6141.
12. Liu YH, Tang Z, Kundu R.K., Wu L., Luo W, Zhu D, Sangiorgi F., Snead ML, Maxson RE. Msx2 gene dosage influences the number of proliferative osteogenic cells in growth centers of the developing murine skull: a possible mechanism for MSX2-mediated craniosynostosis in humans. Dev Biol. 1999; 205(2): 260-274.
13. Satokata I, Ma L, Ohshima H., Bei M, Woo I, Nishizawa K., Maeda T, Takano Y, Uchiyama M., Heaney S, Peters H, Tang Z., Maxson R, Maas R. Msx2 deficiency in mice causes pleiotropic defects in bone growth and ectodermal organ formation. Nat Genet. 2000; 24(4): 391-395.
14. Ma L, Liu J, Wu T., Plikus M, Jiang TX, Bi Q, Liu Y.H., Muller-Rover S, Peters H, Sundberg J.P., Maxson R., Maas RL, Chuong CM. 'Cyclic alopecia' in Msx2 mutants: defects in hair cycling and hair shaft differentiation. Development. 2003; 130(2): 379-389.
15. Chen YH, Ishii M, Sun J., Sucov HM, Maxson RE., Jr Msx1 and Msx2 regulate survival of secondary heart field precursors and post-migratory proliferation of cardiac neural crest in the outflow tract. Dev Biol. 2007; 308(2): 421-437.
16. Ramos C, Robert B. msh/Msx gene family in neural development. Trends Genet. 2005; 21(11): 624-632.
17. Cheng SL, Shao JS, Cai J, Sierra O.L., Towler DA. Msx2 exerts bone anabolism via canonical Wnt signaling. J Biol Chem. 2008; 283(29): 20505-20522.
18. Zhuang F, Liu YH. Usefulness of the luciferase reporter system to test the efficacy of siRNA. Methods Mol Biol. 2006; 342: 181-187.
19. Satokata I, Ma L, Ohshima H., Bei M, Woo I, Nishizawa K., Maeda T, Takano Y, Uchiyama M., Heaney S, Peters H, Tang Z., Maxson R, Maas R. Msx2 deficiency in mice causes pleiotropic defects in bone growth and ectodermal organ formation. Nat Genet. 2000; 24(4): 391-395.
20. Wigle JT, Chowdhury K, Gruss P., Oliver G. Prox1 function is crucial for mice lens-fibre elongation. Nat Genet. 1999; 21(3): 318-322.
21. Dyer MA, Livesey FJ, Cepko C.L., Oliver G. Prox1 function controls progenitor cell proliferation and horizontal cell genesis in the mammalian retina. Nat Genet. 2003; 34(1): 53-58.
22. Misra K, Gui H, Matise MP. Prox1 regulates a transitory state for interneuron neurogenesis in the spinal cord. Dev Dyn. 2008; 237(2): 393-402.
23. Pistocchi A, Gaudenzi G, Carra S., Bresciani E, Del Giacco L, Cotelli F. Crucial role of zebrafish prox1 in hypothalamic catecholaminergic neurons development. BMC Dev Biol. 2008; 8: 27.