-
1
-
-
77956976681
-
Macrophage plasticity and interaction with lymphocyte subsets: cancer as a paradigm
-
Biswas, S. K. and Mantovani, A., Macrophage plasticity and interaction with lymphocyte subsets: cancer as a paradigm. Nat. Immunol. 2010. 11: 889-896.
-
(2010)
Nat. Immunol.
, vol.11
, pp. 889-896
-
-
Biswas, S.K.1
Mantovani, A.2
-
2
-
-
61349100687
-
Myeloid-derived suppressor cells as regulators of the immune system
-
Gabrilovich, D. I. and Nagaraj, S., Myeloid-derived suppressor cells as regulators of the immune system. Nat. Rev. Immunol. 2009. 9: 162-174.
-
(2009)
Nat. Rev. Immunol.
, vol.9
, pp. 162-174
-
-
Gabrilovich, D.I.1
Nagaraj, S.2
-
3
-
-
70350545729
-
Myeloid-derived suppressor cells in inflammation: uncovering cell subsets with enhanced immunosuppressive functions
-
Bronte, V., Myeloid-derived suppressor cells in inflammation: uncovering cell subsets with enhanced immunosuppressive functions. Eur. J. Immunol. 2009. 39: 2670-2672.
-
(2009)
Eur. J. Immunol.
, vol.39
, pp. 2670-2672
-
-
Bronte, V.1
-
4
-
-
34548805636
-
Cross-talk between myeloid-derived suppressor cells and macrophages subverts tumor immunity toward a type 2 response
-
Sinha, P., Clements, V. K., Bunt, S. K., Albelda, S. M. and Ostrand-Rosenberg, S., Cross-talk between myeloid-derived suppressor cells and macrophages subverts tumor immunity toward a type 2 response. J. Immunol. 2007. 179: 977-983.
-
(2007)
J. Immunol.
, vol.179
, pp. 977-983
-
-
Sinha, P.1
Clements, V.K.2
Bunt, S.K.3
Albelda, S.M.4
Ostrand-Rosenberg, S.5
-
5
-
-
34248172324
-
Altered macrophage differentiation and immune dysfunction in tumor development
-
Sica, A. and Bronte, V., Altered macrophage differentiation and immune dysfunction in tumor development. J. Clin. Invest. 2007. 117: 1155-1166.
-
(2007)
J. Clin. Invest.
, vol.117
, pp. 1155-1166
-
-
Sica, A.1
Bronte, V.2
-
6
-
-
78649605467
-
Cannabinoid receptor activation leads to massive mobilization of myeloid-derived suppressor cells with potent immunosuppressive properties
-
Hegde, V. L., Nagarkatti, M. and Nagarkatti, P. S., Cannabinoid receptor activation leads to massive mobilization of myeloid-derived suppressor cells with potent immunosuppressive properties. Eur. J. Immunol. 2010. 40: 3358-3371.
-
(2010)
Eur. J. Immunol.
, vol.40
, pp. 3358-3371
-
-
Hegde, V.L.1
Nagarkatti, M.2
Nagarkatti, P.S.3
-
7
-
-
78649610261
-
IL-1beta regulates a novel myeloid-derived suppressor cell subset that impairs NK cell development and function
-
Elkabets, M., Ribeiro, V. S. G., Dinarello, C. A., Ostrand-Rosemberg, S., Di Santo, J. P., Apte, R. N. and Vosshenrich, C. A. J., IL-1beta regulates a novel myeloid-derived suppressor cell subset that impairs NK cell development and function. Eur. J. Immunol. 2010. 40: 3347-3357.
-
(2010)
Eur. J. Immunol.
, vol.40
, pp. 3347-3357
-
-
Elkabets, M.1
Ribeiro, V.S.G.2
Dinarello, C.A.3
Ostrand-Rosemberg, S.4
Di Santo, J.P.5
Apte, R.N.6
Vosshenrich, C.A.J.7
-
8
-
-
77953914366
-
Tumor-induced tolerance and immune suppression depend on the C/EBPbeta transcription factor
-
Marigo, I., Bosio, E., Solito, S., Mesa, C., Fernandez, A., Dolcetti, L., Ugel, S. et al., Tumor-induced tolerance and immune suppression depend on the C/EBPbeta transcription factor. Immunity 2010. 32: 790-802.
-
(2010)
Immunity
, vol.32
, pp. 790-802
-
-
Marigo, I.1
Bosio, E.2
Solito, S.3
Mesa, C.4
Fernandez, A.5
Dolcetti, L.6
Ugel, S.7
-
9
-
-
68949112132
-
Modulating the expression of IFN regulatory factor 8 alters the protumorigenic behavior of CD11b+Gr-1+ myeloid cells
-
Stewart, T. J., Liewehr, D. J., Steinberg, S. M., Greeneltch, K. M. and Abrams, S. I., Modulating the expression of IFN regulatory factor 8 alters the protumorigenic behavior of CD11b+Gr-1+ myeloid cells. J. Immunol. 2009. 183: 117-128.
-
(2009)
J. Immunol.
, vol.183
, pp. 117-128
-
-
Stewart, T.J.1
Liewehr, D.J.2
Steinberg, S.M.3
Greeneltch, K.M.4
Abrams, S.I.5
-
10
-
-
55849107422
-
Stat3 mediates myeloid cell-dependent tumor angiogenesis in mice
-
Kujawski, M., Kortylewski, M., Lee, H., Herrmann, A., Kay, H. and Yu, H., Stat3 mediates myeloid cell-dependent tumor angiogenesis in mice. J. Clin. Invest. 2008. 118: 3367-3377.
-
(2008)
J. Clin. Invest.
, vol.118
, pp. 3367-3377
-
-
Kujawski, M.1
Kortylewski, M.2
Lee, H.3
Herrmann, A.4
Kay, H.5
Yu, H.6
-
11
-
-
0034671610
-
Immortalized myeloid suppressor cells trigger apoptosis in antigen-activated T lymphocytes
-
Apolloni, E., Bronte, V., Mazzoni, A., Serafini, P., Cabrelle, A., Segal, D. M., Young, H. A. and Zanovello, P., Immortalized myeloid suppressor cells trigger apoptosis in antigen-activated T lymphocytes. J. Immunol. 2000. 165: 6723-6730.
-
(2000)
J. Immunol.
, vol.165
, pp. 6723-6730
-
-
Apolloni, E.1
Bronte, V.2
Mazzoni, A.3
Serafini, P.4
Cabrelle, A.5
Segal, D.M.6
Young, H.A.7
Zanovello, P.8
-
12
-
-
0032400862
-
Vascular endothelial growth factor inhibits the development of dendritic cells and dramatically affects the differentiation of multiple hematopoietic lineages in vivo
-
Gabrilovich, D., Ishida, T., Oyama, T., Ran, S., Kravtsov, V., Nadaf, S. and Carbone, D. P., Vascular endothelial growth factor inhibits the development of dendritic cells and dramatically affects the differentiation of multiple hematopoietic lineages in vivo. Blood 1998. 92: 4150-4166.
-
(1998)
Blood
, vol.92
, pp. 4150-4166
-
-
Gabrilovich, D.1
Ishida, T.2
Oyama, T.3
Ran, S.4
Kravtsov, V.5
Nadaf, S.6
Carbone, D.P.7
-
13
-
-
33846891555
-
Arginase, prostaglandins, and myeloid-derived suppressor cells in renal cell carcinoma
-
Ochoa, A. C., Zea, A. H., Hernandez, C. and Rodriguez, P. C., Arginase, prostaglandins, and myeloid-derived suppressor cells in renal cell carcinoma. Clin. Cancer Res. 2007. 13: 721s-726s.
-
(2007)
Clin. Cancer Res.
, vol.13
-
-
Ochoa, A.C.1
Zea, A.H.2
Hernandez, C.3
Rodriguez, P.C.4
-
14
-
-
34249300128
-
Prostaglandin E2 promotes tumor progression by inducing myeloid-derived suppressor cells
-
Sinha, P., Clements, V. K., Fulton, A. M. and Ostrand-Rosenberg, S., Prostaglandin E2 promotes tumor progression by inducing myeloid-derived suppressor cells. Cancer Res. 2007. 67: 4507-4513.
-
(2007)
Cancer Res.
, vol.67
, pp. 4507-4513
-
-
Sinha, P.1
Clements, V.K.2
Fulton, A.M.3
Ostrand-Rosenberg, S.4
-
15
-
-
29144504335
-
CD11b+/Gr-1+ immature myeloid cells mediate suppression of T cells in mice bearing tumors of IL-1beta-secreting cells
-
Song, X., Krelin, Y., Dvorkin, T., Bjorkdahl, O., Segal, S., Dinarello, C. A., Voronov, E., and Apte, R. N., CD11b+/Gr-1+ immature myeloid cells mediate suppression of T cells in mice bearing tumors of IL-1beta-secreting cells. J. Immunol. 2005. 175: 8200-8208.
-
(2005)
J. Immunol.
, vol.175
, pp. 8200-8208
-
-
Song, X.1
Krelin, Y.2
Dvorkin, T.3
Bjorkdahl, O.4
Segal, S.5
Dinarello, C.A.6
Voronov, E.7
Apte, R.N.8
-
16
-
-
35448954376
-
Reduced inflammation in the tumor microenvironment delays the accumulation of myeloid-derived suppressor cells and limits tumor progression
-
Bunt, S. K., Yang, L., Sinha, P., Clements, V. K., Leips, J. and Ostrand-Rosenberg, S., Reduced inflammation in the tumor microenvironment delays the accumulation of myeloid-derived suppressor cells and limits tumor progression. Cancer Res. 2007. 67: 10019-10026.
-
(2007)
Cancer Res.
, vol.67
, pp. 10019-10026
-
-
Bunt, S.K.1
Yang, L.2
Sinha, P.3
Clements, V.K.4
Leips, J.5
Ostrand-Rosenberg, S.6
-
17
-
-
53049107597
-
Overexpression of interleukin-1beta in the murine pancreas results in chronic pancreatitis
-
Marrache, F., Tu, S. P., Bhagat, G., Pendyala, S., Osterreicher, C. H., Gordon, S., Ramanathan, V. et al., Overexpression of interleukin-1beta in the murine pancreas results in chronic pancreatitis. Gastroenterology 2008. 135: 1277-1287.
-
(2008)
Gastroenterology
, vol.135
, pp. 1277-1287
-
-
Marrache, F.1
Tu, S.P.2
Bhagat, G.3
Pendyala, S.4
Osterreicher, C.H.5
Gordon, S.6
Ramanathan, V.7
-
18
-
-
54549089856
-
Overexpression of interleukin-1beta induces gastric inflammation and cancer and mobilizes myeloid-derived suppressor cells in mice
-
Tu, S., Bhagat, G., Cui, G., Takaishi, S., Kurt-Jones, E. A., Rickman, B., Betz, K. S. et al., Overexpression of interleukin-1beta induces gastric inflammation and cancer and mobilizes myeloid-derived suppressor cells in mice. Cancer Cell 2008. 14: 408-419.
-
(2008)
Cancer Cell
, vol.14
, pp. 408-419
-
-
Tu, S.1
Bhagat, G.2
Cui, G.3
Takaishi, S.4
Kurt-Jones, E.A.5
Rickman, B.6
Betz, K.S.7
-
19
-
-
65449143259
-
Fas signal promotes lung cancer growth by recruiting myeloid-derived suppressor cells via cancer cell-derived PGE2
-
Zhang, Y., Liu, Q., Zhang, M., Yu, Y., Liu, X. and Cao, X., Fas signal promotes lung cancer growth by recruiting myeloid-derived suppressor cells via cancer cell-derived PGE2. J. Immunol. 2009. 182: 3801-3808.
-
(2009)
J. Immunol.
, vol.182
, pp. 3801-3808
-
-
Zhang, Y.1
Liu, Q.2
Zhang, M.3
Yu, Y.4
Liu, X.5
Cao, X.6
-
20
-
-
47949096781
-
Cancer-related inflammation
-
Mantovani, A., Allavena, P., Sica, A. and Balkwill, F., Cancer-related inflammation. Nature 2008. 454: 436-444.
-
(2008)
Nature
, vol.454
, pp. 436-444
-
-
Mantovani, A.1
Allavena, P.2
Sica, A.3
Balkwill, F.4
-
21
-
-
68949181883
-
TIR8/SIGIRR: an IL-1R/TLR family member with regulatory functions in inflammation and T cell polarization
-
Garlanda, C., Anders, H. J. and Mantovani, A., TIR8/SIGIRR: an IL-1R/TLR family member with regulatory functions in inflammation and T cell polarization. Trends Immunol. 2009. 30: 439-446.
-
(2009)
Trends Immunol.
, vol.30
, pp. 439-446
-
-
Garlanda, C.1
Anders, H.J.2
Mantovani, A.3
-
22
-
-
62649139025
-
Immunological and inflammatory functions of the interleukin-1 family
-
Dinarello, C. A., Immunological and inflammatory functions of the interleukin-1 family. Annu. Rev. Immunol. 2009. 27: 519-550.
-
(2009)
Annu. Rev. Immunol.
, vol.27
, pp. 519-550
-
-
Dinarello, C.A.1
-
23
-
-
77949900433
-
Targeting distinct tumor-infiltrating myeloid cells by inhibiting CSF-1 receptor: combating tumor evasion of antiangiogenic therapy
-
Priceman, S. J., Sung, J. L., Shaposhnik, Z., Burton, J. B., Torres-Collado, A. X., Moughon, D. L., Johnson, M. et al., Targeting distinct tumor-infiltrating myeloid cells by inhibiting CSF-1 receptor: combating tumor evasion of antiangiogenic therapy. Blood 2010. 115: 1461-1471.
-
(2010)
Blood
, vol.115
, pp. 1461-1471
-
-
Priceman, S.J.1
Sung, J.L.2
Shaposhnik, Z.3
Burton, J.B.4
Torres-Collado, A.X.5
Moughon, D.L.6
Johnson, M.7
-
24
-
-
43249130187
-
Identification of discrete tumor-induced myeloid-derived suppressor cell subpopulations with distinct T cell-suppressive activity
-
Movahedi, K., Guilliams, M., Van den Bossche, J., Van den Bergh, R., Gysemans, C., Beschin, A., De Baetselier, P. and Van Ginderachter, J. A., Identification of discrete tumor-induced myeloid-derived suppressor cell subpopulations with distinct T cell-suppressive activity. Blood 2008. 111: 4233-4244.
-
(2008)
Blood
, vol.111
, pp. 4233-4244
-
-
Movahedi, K.1
Guilliams, M.2
Van den Bossche, J.3
Van den Bergh, R.4
Gysemans, C.5
Beschin, A.6
De Baetselier, P.7
Van Ginderachter, J.A.8
-
25
-
-
60549088732
-
Arginase I-producing myeloid-derived suppressor cells in renal cell carcinoma are a subpopulation of activated granulocytes
-
Rodriguez, P. C., Ernstoff, M. S., Hernandez, C., Atkins, M., Zabaleta, J., Sierra, R. and Ochoa, A. C., Arginase I-producing myeloid-derived suppressor cells in renal cell carcinoma are a subpopulation of activated granulocytes. Cancer Res. 2009. 69: 1553-1560.
-
(2009)
Cancer Res.
, vol.69
, pp. 1553-1560
-
-
Rodriguez, P.C.1
Ernstoff, M.S.2
Hernandez, C.3
Atkins, M.4
Zabaleta, J.5
Sierra, R.6
Ochoa, A.C.7
-
26
-
-
78049413094
-
Neutrophils influence the level of antigen presentation during the immune response to protein antigens in adjuvants
-
Yang, C.-W., Strong, B. S. I., Miller, M. J. and Unanue, E. R., Neutrophils influence the level of antigen presentation during the immune response to protein antigens in adjuvants. J. Immunol. 2010. 185: 2927-2934.
-
(2010)
J. Immunol.
, vol.185
, pp. 2927-2934
-
-
Yang, C.1
Strong, B.S.I.2
Miller, M.J.3
Unanue, E.R.4
-
27
-
-
70449475343
-
Never underestimate the power of a neutrophil
-
Cassatella, M. A., Locati, M. and Mantovani, A., Never underestimate the power of a neutrophil. Immunity 2009. 31: 698-700.
-
(2009)
Immunity
, vol.31
, pp. 698-700
-
-
Cassatella, M.A.1
Locati, M.2
Mantovani, A.3
-
28
-
-
69249222379
-
Polarization of tumor-associated neutrophil (TAN) phenotype by TGF-beta: "N1" versus "N2" TAN - a new paradigm?
-
Fridlender, Z. G., Sun, J., Kim, S., Kapoor, V., Cheng, G., Ling, L., Worthen, G. S. and Alberlda, S. M., Polarization of tumor-associated neutrophil (TAN) phenotype by TGF-beta: "N1" versus "N2" TAN - a new paradigm? Cancer Cell 2009 16: 183-194.
-
(2009)
Cancer Cell
, vol.16
, pp. 183-194
-
-
Fridlender, Z.G.1
Sun, J.2
Kim, S.3
Kapoor, V.4
Cheng, G.5
Ling, L.6
Worthen, G.S.7
Alberlda, S.M.8
-
29
-
-
77955038532
-
Different tumor microenvironments contain functionally distinct subsets of macrophages derived from Ly6C(high) monocytes
-
Movahedi, K., Laoui, D., Gysemans, C., Baeten, M., Stange, G., Van den Bossche, J., Mack, M. et al., Different tumor microenvironments contain functionally distinct subsets of macrophages derived from Ly6C(high) monocytes. Cancer Res. 2010. 70: 5728-5739.
-
(2010)
Cancer Res.
, vol.70
, pp. 5728-5739
-
-
Movahedi, K.1
Laoui, D.2
Gysemans, C.3
Baeten, M.4
Stange, G.5
Van den Bossche, J.6
Mack, M.7
-
30
-
-
59849126377
-
Cancer-expanded myeloid-derived suppressor cells induce anergy of NK cells through membrane-bound TGF-beta 1
-
Li, H., Han, Y., Guo, Q., Zhang, M. and Cao, X., Cancer-expanded myeloid-derived suppressor cells induce anergy of NK cells through membrane-bound TGF-beta 1. J. Immunol. 2009. 182: 240-249.
-
(2009)
J. Immunol.
, vol.182
, pp. 240-249
-
-
Li, H.1
Han, Y.2
Guo, Q.3
Zhang, M.4
Cao, X.5
-
31
-
-
70350536358
-
Myeloid-derived suppressor cell activation by combined LPS and IFN-gamma treatment impairs DC development
-
Greifenberg, V., Ribechini, E., Rossner, S. and Lutz, M. B., Myeloid-derived suppressor cell activation by combined LPS and IFN-gamma treatment impairs DC development. Eur. J. Immunol. 2009. 39: 2865-2876.
-
(2009)
Eur. J. Immunol.
, vol.39
, pp. 2865-2876
-
-
Greifenberg, V.1
Ribechini, E.2
Rossner, S.3
Lutz, M.B.4
-
32
-
-
58949086448
-
Mononuclear myeloid-derived "suppressor" cells express RAE-1 and activate natural killer cells
-
Nausch, N., Galani, I. E., Schlecker, E. and Cerwenka, A., Mononuclear myeloid-derived "suppressor" cells express RAE-1 and activate natural killer cells. Blood 2008. 112: 4080-4089.
-
(2008)
Blood
, vol.112
, pp. 4080-4089
-
-
Nausch, N.1
Galani, I.E.2
Schlecker, E.3
Cerwenka, A.4
-
33
-
-
78649566580
-
Human natural killer cells and unpolarized or polarized macrophages: molecular interactions and differences in functional outcome
-
In press.
-
Bellora, F., Castriconi, R., Dondero, A., Reggiardo, G., Moretta, L., Mantovani, A., Moretta, A. and Bottino, C., Human natural killer cells and unpolarized or polarized macrophages: molecular interactions and differences in functional outcome. Proc. Natl. Sci. USA 2010. In press.
-
(2010)
Proc. Natl. Sci. USA
-
-
Bellora, F.1
Castriconi, R.2
Dondero, A.3
Reggiardo, G.4
Moretta, L.5
Mantovani, A.6
Moretta, A.7
Bottino, C.8
-
34
-
-
77956680680
-
A novel chemoimmunomodulating property of docetaxel: suppression of myeloid-derived suppressor cells in tumor bearers
-
Kodumudi, K. N., Woan, K., Gilvary, D. L., Sahakian, E., Wei, S. and Djeu, J. Y., A novel chemoimmunomodulating property of docetaxel: suppression of myeloid-derived suppressor cells in tumor bearers. Clin. Cancer Res. 2010. 16: 4583-4594.
-
(2010)
Clin. Cancer Res.
, vol.16
, pp. 4583-4594
-
-
Kodumudi, K.N.1
Woan, K.2
Gilvary, D.L.3
Sahakian, E.4
Wei, S.5
Djeu, J.Y.6
-
35
-
-
25144466458
-
Gemcitabine selectively eliminates splenic Gr-1+/CD11b+ myeloid suppressor cells in tumor-bearing animals and enhances antitumor immune activity
-
Suzuki, E., Kapoor, V., Jassar, A. S., Kaiser, L. R. and Albelda, S. M., Gemcitabine selectively eliminates splenic Gr-1+/CD11b+ myeloid suppressor cells in tumor-bearing animals and enhances antitumor immune activity. Clin. Cancer Res. 2005. 11: 6713-6721.
-
(2005)
Clin. Cancer Res.
, vol.11
, pp. 6713-6721
-
-
Suzuki, E.1
Kapoor, V.2
Jassar, A.S.3
Kaiser, L.R.4
Albelda, S.M.5
-
36
-
-
67349133537
-
Gemcitabine directly inhibits myeloid derived suppressor cells in BALB/c mice bearing 4T1 mammary carcinoma and augments expansion of T cells from tumor-bearing mice
-
Le, H. K., Graham, L., Cha, E., Morales, J. K., Manjili, M. H. and Bear, H. D., Gemcitabine directly inhibits myeloid derived suppressor cells in BALB/c mice bearing 4T1 mammary carcinoma and augments expansion of T cells from tumor-bearing mice. Int. Immunopharmacol. 2009. 9: 900-909.
-
(2009)
Int. Immunopharmacol.
, vol.9
, pp. 900-909
-
-
Le, H.K.1
Graham, L.2
Cha, E.3
Morales, J.K.4
Manjili, M.H.5
Bear, H.D.6
-
37
-
-
63549105681
-
Sunitinib mediates reversal of myeloid-derived suppressor cell accumulation in renal cell carcinoma patients
-
Ko, J. S., Zea, A. H., Rini, B. I., Ireland, J. L., Elson, P., Cohen, P., Golshayan, A. et al., Sunitinib mediates reversal of myeloid-derived suppressor cell accumulation in renal cell carcinoma patients. Clin. Cancer Res. 2009. 15: 2148-2157.
-
(2009)
Clin. Cancer Res.
, vol.15
, pp. 2148-2157
-
-
Ko, J.S.1
Zea, A.H.2
Rini, B.I.3
Ireland, J.L.4
Elson, P.5
Cohen, P.6
Golshayan, A.7
-
38
-
-
77951754469
-
Direct and differential suppression of myeloid-derived suppressor cell subsets by sunitinib is compartmentally constrained
-
Ko, J. S., Rayman, P., Ireland, J., Swaidani, S., Li, G., Bunting, K. D., Rini, B. et al., Direct and differential suppression of myeloid-derived suppressor cell subsets by sunitinib is compartmentally constrained. Cancer Res. 2010. 70: 3526-3536.
-
(2010)
Cancer Res.
, vol.70
, pp. 3526-3536
-
-
Ko, J.S.1
Rayman, P.2
Ireland, J.3
Swaidani, S.4
Li, G.5
Bunting, K.D.6
Rini, B.7
-
39
-
-
0018776553
-
Role of host defense mechanisms in the antitumor activity of adriamycin and daunomycin in mice
-
Mantovani, A., Polentarutti, N., Luini, W., Peri, G. and Spreafico, F., Role of host defense mechanisms in the antitumor activity of adriamycin and daunomycin in mice. J. Natl. Cancer Inst. 1979. 63: 61-66.
-
(1979)
J. Natl. Cancer Inst.
, vol.63
, pp. 61-66
-
-
Mantovani, A.1
Polentarutti, N.2
Luini, W.3
Peri, G.4
Spreafico, F.5
-
40
-
-
59749084216
-
From phagocyte diversity and activation to probiotics: back to Metchnikoff
-
Mantovani, A., From phagocyte diversity and activation to probiotics: back to Metchnikoff. Eur. J. Immunol. 2008. 38: 3269-3273.
-
(2008)
Eur. J. Immunol.
, vol.38
, pp. 3269-3273
-
-
Mantovani, A.1
|