Bone strength and structural deficits in children and adolescents with a distal forearm fracture resulting from mild trauma

Journal of Bone and Mineral Research

Volumn 29, Issue 3, 2014, Pages 590-599

  Farr, Joshua N ^a   Amin, Shreyasee ^a   Melton, L Joseph ^a   Kirmani, Salman ^a   McCready, Louise K ^a   Atkinson, Elizabeth J ^a   Müller, Ralph ^b   Khosla, Sundeep ^a  

^a MAYO CLINIC   (United States)

^b ETH ZURICH   (Switzerland)

Author keywords

bone structure; children; forearm fracture; HRpQCT; trauma levels

Indexed keywords

BONE STRUCTURE; CHILDREN; FOREARM FRACTURE; HRPQCT; TRAUMA LEVELS;

ADOLESCENT; ARM INJURIES; BONE AND BONES; CASE-CONTROL STUDIES; CHILD; CROSS-SECTIONAL STUDIES; FEMALE; FRACTURES, BONE; HUMANS; MALE;

EID: 84894500480     PISSN: 08840431     EISSN: 15234681     Source Type: Journal    
DOI: 10.1002/jbmr.2071     Document Type: Article

References (45)

1. Landin LA., Fracture patterns in children. Analysis of 8,682 fractures with special reference to incidence, etiology and secular changes in a Swedish urban population 1950-1979. Acta Orthop Scand. 1983; 202 (Suppl): 1-109.
2. Kramhoft M, Bodtker S., Epidemiology of distal forearm fractures in Danish children. Acta Orthop Scand. 1988; 59: 557-9.
3. Bailey DA, Wedge JH, McCulloch RG, Martin AD, Bernhardson SC., Epidemiology of fractures of the distal end of the radius in children as associated with growth. J Bone Joint Surg. 1989; 71-A:; 1: 1225-31.
4. Cooper C, Dennison EM, Leufkens HG, Bishop N, van Staa TP., Epidemiology of childhood fractures in Britain: a study using the general practice research database. J Bone Miner Res. 2004; 19 (12): 1976-81.
5. Khosla S, Melton LJ III, Dekutoski MB, Achenbach SJ, Oberg AL, Riggs BL., Incidence of childhood distal forearm fractures over 30 years: a population-based study. JAMA. 2003; 290 (11): 1479-85.
6. Heaney RP, Abrams S, Dawson-Hughes B, et al. Peak bone mass. Osteoporos Int. 2000; 11 (12): 985-1009.
7. Goulding A., Risk factors for fractures in normally active children and adolescents. In:, Daily RM, Petit MA, editors. Optimizing bone mass and strength: the role of physical activity and nutrition during growth. Basel, Switzerland: Karger; p; 102-20. 2007.
8. Clark EM, Tobias JH, Ness AR., Association between bone density and fractures in children: a systematic review and meta-analysis. Pediatrics. 2006; 117: 291-7.
9. Beccard R, Land C, Semler O, et al. Do bone mineral density, bone geometry and the functional muscle-bone unit explain bone fractures in healthy children and adolescents?. Horm Res Paediatr. 2010; 74 (5): 312-8.
10. Parfitt AM., The two faces of growth: benefits and risks to bone integrity. Osteoporos Int. 1994; 4 (6): 382-98.
11. Clark EM, Ness AR, Tobias JH., Bone fragility contributes to the risk of fracture in children, even after moderate and severe trauma. J Bone Miner Res. 2008; 23 (2): 173-9.
12. Bachrach LK., Dual energy X-ray absorptiometry (DEXA) measurements of bone density and body composition: promise and pitfalls. J Pediatr Endocrinol Metab. 2000; 13: (Suppl 2): 983-8.
13. Melton LJ III., History of the Rochester Epidemiology Project. Mayo Clin Proc. 1996; 71 (3): 266-74.
14. Dymond IW., The treatment of isolated fractures of the distal ulna. J Bone Joint Surg Br. 1984; 66 (3): 408-10.
15. Szabo RM, Skinner M., Isolated ulnar shaft fractures. Retrospective study of 46 cases. Acta Orthop Scand. 1990; 61 (4): 350-2.
16. Tanner JM, Healy MJR, Goldstein H, Cameron N., Assessment of skeletal maturity and prediction of adult height (TW3 method). Philadelphia: Saunders; 2001.
17. Rockett HRH, Breitenbach M, Frazier AL, et al. Validation of a youth/adolescent food frequency questionnaire. Prev Med. 1997; 26 (6): 808-16.
18. Rifas-Shiman SL, Gillman MW, Field AE, et al. Comparing physical activity questionnaires for youth: seasonal vs annual format. Am J Prev Med. 2001; 20 (4): 282-5.
19. Kirmani S, Christen D, van Lenthe GH, et al. Bone structure at the distal radius during adolescent growth. J Bone Miner Res. 2009; 24 (6): 1033-42.
20. Pistoia W, van Rietbergen B, Lochmuller EM, Lill CA, Eckstein F, Ruegsegger P., Estimation of distal radius failure load with micro-finite element analysis models based on three-dimensional peripheral quantitative computed tomography images. Bone. 2002; 30 (6): 842-8.
21. Khosla S, Riggs BL, Atkinson EJ, et al. Effects of sex and age on bone microstructure at the ultradistal radius: a population-based noninvasive in vivo assessment. J Bone Miner Res. 2006; 21 (1): 124-31.
22. MacNeil JA, Boyd SK., Accuracy of high-resolution peripheral quantitative computed tomography for measurement of bone quality. Med Eng Phys. 2007; 29 (10): 1096-105.
23. Laib A, Ruegsegger P., Calibration of trabecular bone structure measurements of in vivo three-dimensional peripheral quantitative computed tomography with 28-microm-resolution microcomputed tomography. Bone. 1999; 24 (1): 35-9.
24. Laib A, Hildebrand T, Hauselmann HJ, Ruegsegger P., Ridge number density: a new parameter for in vivo bone structure analysis. Bone. 1997; 21 (6): 541-6.
25. Laib A, Hauselmann HJ, Ruegsegger P., In vivo high resolution 3D-QCT of the human forearm. Technol Health Care. 1998; 6 (5-6): 329-37.
26. Buie HR, Campbell GM, Klinck RJ, MacNeil JA, Boyd SK., Automatic segmentation of cortical and trabecular compartments based on a dual threshold technique for in vivo micro-CT bone analysis. Bone. 2007; 41 (4): 505-15.
27. Burghardt AJ, Buie HR, Laib A, Majumdar S, Boyd SK., Reproducibility of direct quantitative measures of cortical bone microarchitecture of the distal radius and tibia by HR-pQCT. Bone. 2010; 47 (3): 519-28.
28. Farr JN, Charkoudian N, Barnes JN, et al. Relationship of sympathetic activity to bone microstructure, turnover, and plasma osteopontin levels in women. J Clin Endocrinol Metab. 2012; 97 (11): 4219-27.
29. van Rietbergen B, Weinans H, Huiskes R, Odgaard A., A new method to determine trabecular bone elastic properties and loading using micromechanical finite-element models. J Biomech. 1995; 28 (1): 69-81.
30. van Rietbergen B, Odgaard A, Kabel J, Huiskes R., Direct mechanics assessment of elastic symmetries and properties of trabecular bone architecture. J Biomech. 1996; 29 (12): 1653-7.
31. Chiu J, Robinovitch SN., Prediction of upper extremity impact forces during falls on the outstretched hand. J Biomech. 1998; 31 (12): 1169-76.
32. Melton LJ 3rd., Riggs BL, van Lenthe GH, et al. Contribution of in vivo structural measurements and load/strength ratios to the determination of forearm fracture risk in postmenopausal women. J Bone Miner Res. 2007; 22 (9): 1442-8.
33. Gordon CM, Bachrach LK, Carpenter TO, et al. Dual energy X-ray absorptiometry interpretation and reporting in children and adolescents: the 2007 ISCD Pediatric Official Positions. J Clin Densitom. 2008; 11 (1): 43-58.
34. Melton LJ, Khosla S, Riggs BL., Epidemiology of sarcopenia. Mayo Clin Proc. 2000; 75: S10-S3.
35. Wang Q, Wang XF, Iuliano-Burns S, Ghasem-Zadeh A, Zebaze R, Seeman E., Rapid growth produces transient cortical weakness: a risk factor for metaphyseal fractures during puberty. J Bone Miner Res. 2010; 25 (7): 1521-6.
36. Augat P, Gordon CL, Lang TF, Iida H, Genant HK., Accuracy of cortical and trabecular bone measurements with peripheral quantitative computed tomography (pQCT). Phys Med Biol. 1998; 43: 2873-83.
37. Chevalley T, Bonjour JP, van Rietbergen B, Ferrari S, Rizzoli R., Fractures during childhood and adolescence in healthy boys: relation with bone mass, microstructure, and strength. J Clin Endocrinol Metab. 2011; 96 (10): 3134-42.
38. Goulding A, Grant AM, Williams SM., Bone and body composition of children and adolescents with repeated forearm fractures. J Bone Miner Res. 2005; 20 (12): 2090-6.
39. Dimitri P, Wales JK, Bishop N., Fat and bone in children: differential effects of obesity on bone size and mass according to fracture history. J Bone Miner Res. 2010; 25 (3): 527-36.
40. Dimitri P, Bishop N, Walsh JS, Eastell R., Obesity is a risk factor for fracture in children but is protective against fracture in adults: a paradox. Bone. 2012; 50 (2): 457-66.
41. Amin S, Melton LJ, Achenbach SJ, et al. A distal forearm fracture in childhood increases the risk for fracture during adulthood in men, but not in women. J Bone Miner Res. 2013; 28 (8): 1751-9.
42. Ferrari S, Rizzoli R, Slosman D, Bonjour JP., Familial resemblance for bone mineral mass is expressed before puberty. J Clin Endocrinol Metab. 1998; 83 (2): 358-61.
43. Loro ML, Sayre J, Roe TF, Goran MI, Kaufman FR, Gilsanz V., Early identification of children predisposed to low peak bone mass and osteoporosis later in life. J Clin Endocrinol Metab. 2000; 85 (10): 3908-18.
44. Wang Q, Cheng S, Alen M, Seeman E., Bone's structural diversity in adult females is established before puberty. J Clin Endocrinol Metab. 2009; 94 (5): 1555-61.
45. Rauch F, Plotkin H, DiMeglio L, et al. Fracture prediction and the definition of osteoporosis in children and adolescents: the ISCD 2007 Pediatric Official Positions. J Clin Densitom. 2008; 11 (1): 22-8.