Promotion of enzyme flexibility by dephosphorylation and coupling to the catalytic mechanism of a phosphohexomutase

Journal of Biological Chemistry

Volumn 289, Issue 8, 2014, Pages 4674-4682

  Lee, Yingying ^a   Villar, Maria T ^b   Artigues, Antonio ^b   Beamer, Lesa J ^a,c  

^a UNIVERSITY OF MISSOURI   (United States)

^b UNIVERSITY OF KANSAS SCHOOL OF MEDICINE   (United States)

^c University of Missouri   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CATALYSIS;

CATALYTIC MECHANISMS; CONFORMATIONAL CHANGE; DEPHOSPHORYLATIONS; ENZYME FUNCTIONS; INCREASED FLEXIBILITY; PHOSPHO-TRANSFER; PHOSPHORYL TRANSFER;

ENZYMES;

DEUTERIUM; GLUCOSE 6 PHOSPHATE ISOMERASE; HYDROGEN; PHOSPHOGLUCOMUTASE; PHOSPHOMANNOMUTASE;

ARTICLE; CONTROLLED STUDY; DEPHOSPHORYLATION; DEUTERIUM HYDROGEN EXCHANGE; ENZYME CONFORMATION; ENZYME MECHANISM; ENZYME PHOSPHORYLATION; ENZYME STRUCTURE; LIGAND BINDING; MASS SPECTROMETRY; NONHUMAN; PRIORITY JOURNAL; PSEUDOMONAS AERUGINOSA; X RAY CRYSTALLOGRAPHY;

CARBOHYDRATE BIOSYNTHESIS; ENZYME CATALYSIS; HYDROGEN-DEUTERIUM EXCHANGE; PHOSPHORYLATION; PROTEIN DYNAMICS; PSEUDOMONAS AERUGINOSA; SMALL ANGLE X-RAY SCATTERING;

BIOCATALYSIS; CATALYTIC DOMAIN; CRYSTALLOGRAPHY, X-RAY; DEUTERIUM EXCHANGE MEASUREMENT; LIGANDS; MASS SPECTROMETRY; MODELS, MOLECULAR; PHOSPHOGLUCOMUTASE; PHOSPHORYLATION; PHOSPHOTRANSFERASES (PHOSPHOMUTASES); PLIABILITY; PROTEIN STRUCTURE, TERTIARY; PSEUDOMONAS AERUGINOSA; SCATTERING, SMALL ANGLE; SOLUTIONS; TIME FACTORS;

EID: 84894494466     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M113.532226     Document Type: Article

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