메뉴 건너뛰기




Volumn 78, Issue 3, 2014, Pages 679-684

Pharmacodynamic comparison of pitavastatin versus atorvastatin on platelet reactivity in patients with coronary artery disease treated with dual antiplatelet therapy: The PORTO trial

Author keywords

Clopidogrel; Coronary artery disease; Percutaneous coronary intervention; Platelet reactivity

Indexed keywords

ACETYLSALICYLIC ACID PLUS CLOPIDOGREL; AMINOTRANSFERASE; ANGIOTENSIN RECEPTOR ANTAGONIST; ANTICOAGULANT AGENT; ANTITHROMBOCYTIC AGENT; ATORVASTATIN; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; HEPARIN; PITAVASTATIN; ACETYLSALICYLIC ACID; CLOPIDOGREL; CYP3A4 PROTEIN, HUMAN; CYTOCHROME P450 3A; HEPTANOIC ACID DERIVATIVE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; PYRROLE DERIVATIVE; QUINOLINE DERIVATIVE; TICLOPIDINE;

EID: 84894466932     PISSN: 13469843     EISSN: 13474820     Source Type: Journal    
DOI: 10.1253/circj.CJ-13-1216     Document Type: Article
Times cited : (15)

References (34)
  • 1
    • 84865488153 scopus 로고    scopus 로고
    • Predictors of high on-treatment platelet reactivity early after clopidogrel loading in ST-elevation myocardial infarction
    • Alexopoulos D, Xanthopoulou I, Tsigkas G, Damelou A, Theodoropoulos KC, Kassimis G, et al. Predictors of high on-treatment platelet reactivity early after clopidogrel loading in ST-elevation myocardial infarction. Circ J 2012; 76: 2183-2187
    • (2012) Circ J , vol.76 , pp. 2183-2187
    • Alexopoulos, D.1    Xanthopoulou, I.2    Tsigkas, G.3    Damelou, A.4    Theodoropoulos, K.C.5    Kassimis, G.6
  • 2
    • 84857588954 scopus 로고    scopus 로고
    • Impact of platelet reactivity to adenosine diphosphate before implantation of drug-eluting stents on subsequent adverse cardiac events in patients with stable angina
    • Motoda C, Ueda H, Hayashi Y, Toyofuku M, Okimoto T, Otsuka M, et al. Impact of platelet reactivity to adenosine diphosphate before implantation of drug-eluting stents on subsequent adverse cardiac events in patients with stable angina. Circ J 2012; 76: 641-649
    • (2012) Circ J , vol.76 , pp. 641-649
    • Motoda, C.1    Ueda, H.2    Hayashi, Y.3    Toyofuku, M.4    Okimoto, T.5    Otsuka, M.6
  • 3
    • 34447332809 scopus 로고    scopus 로고
    • Clopidogrel-statin interaction: Myth or reality?
    • Angiolillo DJ, Alfonso F. Clopidogrel-statin interaction: Myth or reality? J Am Coll Cardiol 2007; 50: 296-298
    • (2007) J Am Coll Cardiol , vol.50 , pp. 296-298
    • Angiolillo, D.J.1    Alfonso, F.2
  • 5
    • 84861594738 scopus 로고    scopus 로고
    • CREDO-Kyoto PCI/CABG registry cohort-2 investigators. Intensity of statin therapy, achieved low-density lipoprotein cholesterol levels and cardiovascular outcomes in Japanese patients after coronary revascularization: Perspectives from the CREDO-Kyoto registry cohort-2
    • Natsuaki M, Furukawa Y, Morimoto T, Nakagawa Y, Ono K, Kaburagi S, et al; CREDO-Kyoto PCI/CABG registry cohort-2 investigators. Intensity of statin therapy, achieved low-density lipoprotein cholesterol levels and cardiovascular outcomes in Japanese patients after coronary revascularization: Perspectives from the CREDO-Kyoto registry cohort-2. Circ J 2012; 76: 1369-1379
    • (2012) Circ J , vol.76 , pp. 1369-1379
    • Natsuaki, M.1    Furukawa, Y.2    Morimoto, T.3    Nakagawa, Y.4    Ono, K.5    Kaburagi, S.6
  • 6
    • 84870495078 scopus 로고    scopus 로고
    • JAPAN-ACS Investigators. Clustering of metabolic syndrome components attenuates coronary plaque regression during intensive statin therapy in patients with acute coronary syndrome: The JAPANACS subanalysis study
    • Takashima H, Ozaki Y, Morimoto T, Kimura T, Hiro T, Miyauchi K, et al; JAPAN-ACS Investigators. Clustering of metabolic syndrome components attenuates coronary plaque regression during intensive statin therapy in patients with acute coronary syndrome: The JAPANACS subanalysis study. Circ J 2012; 76: 2840-2847
    • (2012) Circ J , vol.76 , pp. 2840-2847
    • Takashima, H.1    Ozaki, Y.2    Morimoto, T.3    Kimura, T.4    Hiro, T.5    Miyauchi, K.6
  • 7
    • 84869114800 scopus 로고    scopus 로고
    • Atorvastatin accelerates both neointimal coverage and re-endothelialization after sirolimus-eluting stent implantation in a porcine model: New findings from optical coherence tomography and pathology
    • Wang TJ, Yang YJ, Xu B, Zhang Q, Jin C, Tang Y, et al. Atorvastatin accelerates both neointimal coverage and re-endothelialization after sirolimus-eluting stent implantation in a porcine model: New findings from optical coherence tomography and pathology. Circ J 2012; 76: 2561-2571
    • (2012) Circ J , vol.76 , pp. 2561-2571
    • Wang, T.J.1    Yang, Y.J.2    Xu, B.3    Zhang, Q.4    Jin, C.5    Tang, Y.6
  • 8
    • 84870487971 scopus 로고    scopus 로고
    • Effects of pitavastatin on cardiac structure and function and on prevention of atrial fibrillation in elderly hypertensive patients: A prospective study of 2-years' follow-up
    • Warita S, Kawasaki M, Tanaka R, Ono K, Kojima T, Hirose T, et al. Effects of pitavastatin on cardiac structure and function and on prevention of atrial fibrillation in elderly hypertensive patients: A prospective study of 2-years' follow-up. Circ J 2012; 76: 2755-2762
    • (2012) Circ J , vol.76 , pp. 2755-2762
    • Warita, S.1    Kawasaki, M.2    Tanaka, R.3    Ono, K.4    Kojima, T.5    Hirose, T.6
  • 9
    • 84869118379 scopus 로고    scopus 로고
    • Virtual histology findings and effects of varying doses of atorvastatin on coronary plaque volume and composition in statin-naive patients: The VENUS study
    • Lee SW, Hau WK, Kong SL, Chan KK, Chan PH, Lam SC, et al. Virtual histology findings and effects of varying doses of atorvastatin on coronary plaque volume and composition in statin-naive patients: The VENUS study. Circ J 2012; 76: 2662-2672
    • (2012) Circ J , vol.76 , pp. 2662-2672
    • Lee, S.W.1    Hau, W.K.2    Kong, S.L.3    Chan, K.K.4    Chan, P.H.5    Lam, S.C.6
  • 10
    • 0034911702 scopus 로고    scopus 로고
    • ADP receptors of platelets and their inhibition
    • Gachet C. ADP receptors of platelets and their inhibition. Thromb Haemost 2001; 86: 222-232
    • (2001) Thromb Haemost , vol.86 , pp. 222-232
    • Gachet, C.1
  • 11
    • 13444251203 scopus 로고    scopus 로고
    • Chemical, pharmacokinetic and pharmacodynamic properties of statins: An update
    • Schachter M. Chemical, pharmacokinetic and pharmacodynamic properties of statins: An update. Fundam Clin Pharmacol 2005; 19: 117-125
    • (2005) Fundam Clin Pharmacol , vol.19 , pp. 117-125
    • Schachter, M.1
  • 12
    • 0035204867 scopus 로고    scopus 로고
    • Pitavastatin (NK-104), a new HMG-CoA reductase inhibitor
    • Isley W. Pitavastatin (NK-104), a new HMG-CoA reductase inhibitor. Drugs Today 2001; 37: 587-594
    • (2001) Drugs Today , vol.37 , pp. 587-594
    • Isley, W.1
  • 13
    • 0036406733 scopus 로고    scopus 로고
    • Metabolic fate of pitavastatin (NK-104), a new inhibitor of 3-hydroxy-3-methyl-glutaryl coenzyme A reductase: Effects on drug-metabolizing systems in rats and humans
    • Fujino H, Yamada I, Shimada S, Nagao T, Yoneda M. Metabolic fate of pitavastatin (NK-104), a new inhibitor of 3-hydroxy-3-methyl-glutaryl coenzyme A reductase: Effects on drug-metabolizing systems in rats and humans. Arzneimittelforschung 2002; 52: 745-753
    • (2002) Arzneimittelforschung , vol.52 , pp. 745-753
    • Fujino, H.1    Yamada, I.2    Shimada, S.3    Nagao, T.4    Yoneda, M.5
  • 14
    • 11244283910 scopus 로고    scopus 로고
    • Metabolic properties of the acid and lactone forms of HMG-CoA reductase inhibitors
    • Fujino H, Saito S, Tsunemari Y, Kojima J, Sakaeda T. Metabolic properties of the acid and lactone forms of HMG-CoA reductase inhibitors. Xenobiotica 2004; 34: 961-971
    • (2004) Xenobiotica , vol.34 , pp. 961-971
    • Fujino, H.1    Saito, S.2    Tsunemari, Y.3    Kojima, J.4    Sakaeda, T.5
  • 15
    • 4644364576 scopus 로고    scopus 로고
    • Contribution of OATP2 (OATP1B1) and OATP8 (OATP1B3) to the hepatic uptake of pitavastatin in humans
    • Hirano M, Maeda K, Shitara Y, Sugiyama Y. Contribution of OATP2 (OATP1B1) and OATP8 (OATP1B3) to the hepatic uptake of pitavastatin in humans. J Pharmacol Exp Ther 2004; 311: 139-146
    • (2004) J Pharmacol Exp Ther , vol.311 , pp. 139-146
    • Hirano, M.1    Maeda, K.2    Shitara, Y.3    Sugiyama, Y.4
  • 17
    • 33745877645 scopus 로고    scopus 로고
    • Validation of VerifyNow-P2Y12 cartridge for monitoring platelet inhibition with clopidogrel
    • Malinin A, Pokov A, Swaim L, Kotob M, Serebruany V. Validation of VerifyNow-P2Y12 cartridge for monitoring platelet inhibition with clopidogrel. Methods Find Exp Clin Pharmacol 2006; 28: 315-322
    • (2006) Methods Find Exp Clin Pharmacol , vol.28 , pp. 315-322
    • Malinin, A.1    Pokov, A.2    Swaim, L.3    Kotob, M.4    Serebruany, V.5
  • 18
    • 84861857758 scopus 로고    scopus 로고
    • A randomized trial of prasugrel versus clopidogrel in patients with high platelet reactivity on clopidogrel after elective percutaneous coronary intervention with implantation of drug-eluting stents: Results of the TRIGGER-PCI (Testing Platelet Reactivity In Patients Undergoing Elective Stent Placement on Clopidogrel to Guide Alternative Therapy With Prasugrel) study
    • Trenk D, Stone GW, Gawaz M, Kastrati A, Angiolillo DJ, Müller U, et al. A randomized trial of prasugrel versus clopidogrel in patients with high platelet reactivity on clopidogrel after elective percutaneous coronary intervention with implantation of drug-eluting stents: Results of the TRIGGER-PCI (Testing Platelet Reactivity In Patients Undergoing Elective Stent Placement on Clopidogrel to Guide Alternative Therapy With Prasugrel) study. J Am Coll Cardiol 2012; 59: 2159-2164
    • (2012) J Am Coll Cardiol , vol.59 , pp. 2159-2164
    • Trenk, D.1    Stone, G.W.2    Gawaz, M.3    Kastrati, A.4    Angiolillo, D.J.5    Müller, U.6
  • 19
    • 79952598836 scopus 로고    scopus 로고
    • GRAVITAS Investigators. Standard- vs high-dose clopidogrel based on platelet function testing after percutaneous coronary intervention: The GRAVITAS randomized trial
    • Price MJ, Berger PB, Teirstein PS, Tanguay JF, Angiolillo DJ, Spriggs D, et al; GRAVITAS Investigators. Standard- vs high-dose clopidogrel based on platelet function testing after percutaneous coronary intervention: The GRAVITAS randomized trial. JAMA 2011; 305: 1097-1105
    • (2011) JAMA , vol.305 , pp. 1097-1105
    • Price, M.J.1    Berger, P.B.2    Teirstein, P.S.3    Tanguay, J.F.4    Angiolillo, D.J.5    Spriggs, D.6
  • 20
    • 0028839815 scopus 로고
    • Estimating sample sizes for binary, ordered categorical, and continuous outcomes in two group comparisons
    • Campbell MJ, Julious SA, Altman DG. Estimating sample sizes for binary, ordered categorical, and continuous outcomes in two group comparisons. BMJ 1995; 311: 1145-1148
    • (1995) BMJ , vol.311 , pp. 1145-1148
    • Campbell, M.J.1    Julious, S.A.2    Altman, D.G.3
  • 21
    • 0037422534 scopus 로고    scopus 로고
    • Atorvastatin reduces the ability of clopidogrel to inhibit platelet aggregation: A new drug-drug interaction
    • Lau WC, Waskell LA, Watkins PB, Neer CJ, Horowitz K, Hopp AS, et al. Atorvastatin reduces the ability of clopidogrel to inhibit platelet aggregation: A new drug-drug interaction. Circulation 2003; 107: 32-37
    • (2003) Circulation , vol.107 , pp. 32-37
    • Lau, W.C.1    Waskell, L.A.2    Watkins, P.B.3    Neer, C.J.4    Horowitz, K.5    Hopp, A.S.6
  • 22
    • 84995268247 scopus 로고    scopus 로고
    • CASTOR investigators. Influence of statin treatment on platelet inhibition by clopidogrel: A randomized comparison of rosuvastatin, atorvastatin and simvastatin co-treatment
    • Malmström RE, Ostergren J, Jørgensen L, Hjemdahl P; CASTOR investigators. Influence of statin treatment on platelet inhibition by clopidogrel: A randomized comparison of rosuvastatin, atorvastatin and simvastatin co-treatment. Eur J Clin Invest 2005; 35: 476-481
    • (2005) Eur J Clin Invest , vol.35 , pp. 476-481
    • Malmström, R.E.1    Ostergren, J.2    Jørgensen, L.3    Hjemdahl, P.4
  • 23
    • 84894426131 scopus 로고    scopus 로고
    • The antiplatelet effect of clopidogrel is not attenuated by statin treatment in stable patients with ischemic heart disease
    • Vinholt P, Poulsen TS, Korsholm L, Kristensen SR, Hallas J, Damkier P, et al. The antiplatelet effect of clopidogrel is not attenuated by statin treatment in stable patients with ischemic heart disease. J Intern Med 2009; 266: 457-466
    • (2009) J Intern Med , vol.266 , pp. 457-466
    • Vinholt, P.1    Poulsen, T.S.2    Korsholm, L.3    Kristensen, S.R.4    Hallas, J.5    Damkier, P.6
  • 24
    • 6344226832 scopus 로고    scopus 로고
    • Absence of interaction between atorvastatin or other statins and clopidogrel: Results from the interaction study
    • Serebruany VL, Midei MG, Malinin AI, Oshrine BR, Lowry DR, Sane DC, et al. Absence of interaction between atorvastatin or other statins and clopidogrel: Results from the interaction study. Arch Intern Med 2004; 164: 2051-2057
    • (2004) Arch Intern Med , vol.164 , pp. 2051-2057
    • Serebruany, V.L.1    Midei, M.G.2    Malinin, A.I.3    Oshrine, B.R.4    Lowry, D.R.5    Sane, D.C.6
  • 25
    • 1642410985 scopus 로고    scopus 로고
    • Atorvastatin does not affect the antiplatelet potency of clopidogrel when it is administered concomitantly for 5 weeks in patients with acute coronary syndromes
    • Mitsios JV, Papathanasiou AI, Rodis FI, Elisaf M, Goudevenos JA, Tselepis AD. Atorvastatin does not affect the antiplatelet potency of clopidogrel when it is administered concomitantly for 5 weeks in patients with acute coronary syndromes. Circulation 2004; 109: 1335-1338
    • (2004) Circulation , vol.109 , pp. 1335-1338
    • Mitsios, J.V.1    Papathanasiou, A.I.2    Rodis, F.I.3    Elisaf, M.4    Goudevenos, J.A.5    Tselepis, A.D.6
  • 26
    • 84866072438 scopus 로고    scopus 로고
    • Accelerated platelet inhibition by switching from atorvastatin to a non- CYP3A4-metabolized statin in patients with high platelet reactivity (ACCEL-STATIN) study
    • Park Y, Jeong YH, Tantry US, Ahn JH, Kwon TJ, Park JR, et al. Accelerated platelet inhibition by switching from atorvastatin to a non- CYP3A4-metabolized statin in patients with high platelet reactivity (ACCEL-STATIN) study. Eur Heart J 2012; 33: 2151-2162
    • (2012) Eur Heart J , vol.33 , pp. 2151-2162
    • Park, Y.1    Jeong, Y.H.2    Tantry, U.S.3    Ahn, J.H.4    Kwon, T.J.5    Park, J.R.6
  • 27
    • 15344341734 scopus 로고    scopus 로고
    • Differential interaction of 3-hydroxy-3-methylglutaryl-coa reductase inhibitors with ABCB1, ABCC2, and OATP1B1
    • Chen C, Mireles RJ, Campbell SD, Lin J, Mills JB, Xu JJ, et al. Differential interaction of 3-hydroxy-3-methylglutaryl-coa reductase inhibitors with ABCB1, ABCC2, and OATP1B1. Drug Metab Dispos 2005; 33: 537-546
    • (2005) Drug Metab Dispos , vol.33 , pp. 537-546
    • Chen, C.1    Mireles, R.J.2    Campbell, S.D.3    Lin, J.4    Mills, J.B.5    Xu, J.J.6
  • 28
    • 33644913688 scopus 로고    scopus 로고
    • Effects of acid and lactone forms of eight HMG-CoA reductase inhibitors on CYP-mediated metabolism and MDR1-mediated transport
    • Sakaeda T, Fujino H, Komoto C, Kakumoto M, Jin JS, Iwaki K, et al. Effects of acid and lactone forms of eight HMG-CoA reductase inhibitors on CYP-mediated metabolism and MDR1-mediated transport. Pharm Res 2006; 23: 506-512
    • (2006) Pharm Res , vol.23 , pp. 506-512
    • Sakaeda, T.1    Fujino, H.2    Komoto, C.3    Kakumoto, M.4    Jin, J.S.5    Iwaki, K.6
  • 29
    • 33845420011 scopus 로고    scopus 로고
    • Drug interactions with lipidlowering drugs: Mechanisms and clinical relevance
    • Neuvonen PJ, Niemi M, Backman JT. Drug interactions with lipidlowering drugs: Mechanisms and clinical relevance. Clin Pharmacol Ther 2006; 80: 565-581
    • (2006) Clin Pharmacol Ther , vol.80 , pp. 565-581
    • Neuvonen, P.J.1    Niemi, M.2    Backman, J.T.3
  • 30
    • 77953819724 scopus 로고    scopus 로고
    • Pitavastatin: A distinctive lipid lowering drug
    • Ose L. Pitavastatin: A distinctive lipid lowering drug. Clin Lipidol 2010; 5: 309-323
    • (2010) Clin Lipidol , vol.5 , pp. 309-323
    • Ose, L.1
  • 31
    • 78650553915 scopus 로고    scopus 로고
    • Pitavastatin: Pharmacological profile from early phase studies
    • Catapano AL. Pitavastatin: Pharmacological profile from early phase studies. Atheroscler Suppl 2010; 11: 3-7
    • (2010) Atheroscler Suppl , vol.11 , pp. 3-7
    • Catapano, A.L.1
  • 33
    • 84878249363 scopus 로고    scopus 로고
    • Relationship between CYP2C19 loss-offunction polymorphism and platelet reactivities with clopidogrel treatment in Japanese patients undergoing coronary stent implantation
    • Nakata T, Miyahara M, Nakatani K, Wada H, Tanigawa T, Komada F, et al; McLordd Group. Relationship between CYP2C19 loss-offunction polymorphism and platelet reactivities with clopidogrel treatment in Japanese patients undergoing coronary stent implantation. Circ J 2013; 77: 1436-1444
    • (2013) Circ J , vol.77 , pp. 1436-1444
    • Nakata, T.1    Miyahara, M.2    Nakatani, K.3    Wada, H.4    Tanigawa, T.5    Komada, F.6
  • 34
    • 79958110089 scopus 로고    scopus 로고
    • Prospective evaluation of on-clopidogrel platelet reactivity over time in patients treated with percutaneous coronary intervention: Relationship gene polymorphisms clinical outcomes
    • Campo G, Parrinello G, Ferraresi P, Lunghi B, Tebaldi M, Miccoli M, et al. Prospective evaluation of on-clopidogrel platelet reactivity over time in patients treated with percutaneous coronary intervention: Relationship gene polymorphisms clinical outcomes. J Am Coll Cardiol 2011; 57: 2474-2483.
    • (2011) J Am Coll Cardiol , vol.57 , pp. 2474-2483
    • Campo, G.1    Parrinello, G.2    Ferraresi, P.3    Lunghi, B.4    Tebaldi, M.5    Miccoli, M.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.