Effectiveness of local vancomycin powder to decrease surgical site infections: A meta-analysis

Spine Journal

Volumn 14, Issue 3, 2014, Pages 397-407

  Chiang, Hsiu Yin ^a   Herwaldt, Loreen A ^a,b   Blevins, Amy E ^b   Cho, Edward ^a   Schweizer, Marin L ^a,b,c  

^a UNIVERSITY OF IOWA   (United States)

^b UNIVERSITY OF IOWA   (United States)

^c VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

Meta analysis; Prophylaxis; Spinal operation; Staphylococcus aureus; Surgical site infections; Vancomycin powder

Indexed keywords

ANTIINFECTIVE AGENT; POWDER; VANCOMYCIN;

HUMAN; INCIDENCE; META ANALYSIS; MICROBIOLOGY; OUTCOME ASSESSMENT; POWDER; STAPHYLOCOCCAL INFECTIONS; STAPHYLOCOCCUS AUREUS; SURGICAL WOUND INFECTION; TREATMENT OUTCOME;

ANTI-INFECTIVE AGENTS; HUMANS; INCIDENCE; OUTCOME ASSESSMENT (HEALTH CARE); POWDERS; STAPHYLOCOCCAL INFECTIONS; STAPHYLOCOCCUS AUREUS; SURGICAL WOUND INFECTION; TREATMENT OUTCOME; VANCOMYCIN;

EID: 84894460161     PISSN: 15299430     EISSN: 18781632     Source Type: Journal    
DOI: 10.1016/j.spinee.2013.10.012     Document Type: Article

References (30)

1. R.M. Klevens, J.R. Edwards, and C.L. Richards Jr. et al. Estimating health care-associated infections and deaths in U.S. hospitals, 2002 Public Health Rep 122 2007 160 166
2. L.A. Herwaldt, J.J. Cullen, and D. Scholz et al. A prospective study of outcomes, healthcare resource utilization, and costs associated with postoperative nosocomial infections Infect Control Hosp Epidemiol 27 2006 1291 1298
3. G. de Lissovoy, K. Fraeman, and V. Hutchins et al. Surgical site infection: incidence and impact on hospital utilization and treatment costs Am J Infect Control 37 2009 387 397
4. J.R. Edwards, K.D. Peterson, and Y. Mu et al. National Healthcare Safety Network (NHSN) report: data summary for 2006 through 2008, issued December 2009 Am J Infect Control 37 2009 783 805
5. A.I. Hidron, J.R. Edwards, and J. Patel et al. NHSN annual update: antimicrobial-resistant pathogens associated with healthcare-associated infections: annual summary of data reported to the National Healthcare Safety Network at the Centers for Disease Control and Prevention, 2006-2007 Infect Control Hosp Epidemiol 29 2008 996 1011
6. D.J. Anderson, D.J. Sexton, and Z.A. Kanafani et al. Severe surgical site infection in community hospitals: epidemiology, key procedures, and the changing prevalence of methicillin-resistant Staphylococcus aureus Infect Control Hosp Epidemiol 28 2007 1047 1053
7. K. Gupta, J. Strymish, and Y. Abi-Haidar et al. Preoperative nasal methicillin-resistant Staphylococcus aureus status, surgical prophylaxis, and risk-adjusted postoperative outcomes in veterans Infect Control Hosp Epidemiol 32 2011 791 796
8. G. Sakoulas, P.A. Moise-Broder, and J. Schentag et al. Relationship of MIC and bactericidal activity to efficacy of vancomycin for treatment of methicillin-resistant Staphylococcus aureus bacteremia J Clin Microbiol 42 2004 2398 2402
9. G.L. French Bactericidal agents in the treatment of MRSA infections - the potential role of daptomycin J Antimicrob Chemother 58 2006 1107 1117
10. P.C. Appelbaum The emergence of vancomycin-intermediate and vancomycin-resistant Staphylococcus aureus Clin Microbiol Infect 12 1 Suppl 2006 16 23
11. F.A. Sweet, M. Roh, and C. Sliva Intrawound application of vancomycin for prophylaxis in instrumented thoracolumbar fusions: efficacy, drug levels, and patient outcomes Spine 36 2011 2084 2088
12. H.L. Lazar, T. Barlam, and H. Cabral The effect of topical vancomycin applied to sternotomy incisions on postoperative serum vancomycin levels J Card Surg 26 2011 461 465
13. D. Moher, A. Liberati, and J. Tetzlaff et al. Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement Int J Surg 8 2010 336 341
14. D.F. Stroup, J.A. Berlin, and S.C. Morton et al. Meta-analysis of observational studies in epidemiology: a proposal for reporting. Meta-analysis of Observational Studies in Epidemiology (MOOSE) group JAMA 283 2000 2008 2012
15. Review Manager (RevMan) [Computer program]. Version 5.2. Copenhagen: The Nordic Cochrane Centre, The Cochrane Collaboration, 2012.
16. J. Kennelly Methodological approach to assessing the evidence A. Handler, J. Kennelly, N. Peacock, Reducing racial/ethnic disparities in reproductive and perinatal outcomes: the evidence from population-based interventions 2010 Springer New York, NY 7 20
17. S.H. Downs, and N. Black The feasibility of creating a checklist for the assessment of the methodological quality both of randomised and non-randomised studies of health care interventions J Epidemiol Community Health 52 1998 377 384
18. T.J. Vander Salm, O.N. Okike, and M.K. Pasque et al. Reduction of sternal infection by application of topical vancomycin J Thorac Cardiovasc Surg 98 1989 618 622
19. K.R. O'Neill, J.G. Smith, and A.M. Abtahi et al. Reduced surgical site infections in patients undergoing posterior spinal stabilization of traumatic injuries using vancomycin powder Spine J 11 2011 641 646
20. Rahman RK, Lenke LG, Bridwell KH, et al. Intrawound vancomycin powder lowers the acute deep wound infection rate in adult spinal deformity patients. Paper presented at: Scoliosis Research Society 46th Annual Meeting & Course; September 14-17, 2011; Louisville, KY.
21. A. Heller The effect of intrawound vancomycin powder on surgical site infections in posterior instrumented spinal arthrodeses [1519071] 2012 University of Kansas Lawrence, KS
22. S. Mohammed, G.T. Pisimisis, and S.P. Daram et al. Impact of intraoperative administration of local vancomycin on inguinal wound complications J Vasc Surg 57 2013 1079 1083
23. R.G. Strom, D. Pacione, S.P. Kalhorn, and A.K. Frempong-Boadu Decreased risk of wound infection after posterior cervical fusion with routine local application of vancomycin powder Spine 38 2013 991 994
24. J.M. Pahys, J.R. Pahys, and S.K. Cho et al. Methods to decrease postoperative infections following posterior cervical spine surgery J Bone Joint Surg Am 95 2013 549 554
25. R.G. Strom, D. Pacione, S.P. Kalhorn, and A.K. Frempong-Boadu Lumbar laminectomy and fusion with routine local application of vancomycin powder: decreased infection rate in instrumented and non-instrumented cases Clin Neurol Neurosurg 115 2013 1766 1769
26. C. Caroom, J.M. Tullar, and E.G. Benton Jr. et al. Intrawound vancomycin powder reduces surgical site infections in posterior cervical fusion Spine 38 2013 1183 1187
27. Division of Healthcare Quality Promotion, National Center for Preparedness, Detection and Control of Infectious Diseases The National Healthcare Safety Network (NHSN) manual: patient safety component protocol: 9-1-9-14 2009 Division of Healthcare Quality Promotion, National Center for Preparedness, Detection and Control of Infectious Diseases Atlanta, GA Available at: http://www.cdc.gov/nhsn/PDFs/pscManual/pscManual-current.pdf Accessed June 11, 2013
28. R.W. Molinari, O.A. Khera, and W.J. Molinari 3rd Prophylactic intraoperative powdered vancomycin and postoperative deep spinal wound infection: 1,512 consecutive surgical cases over a 6-year period Eur Spine J 21 2012 S476 S482
29. W.W. Kanj, J.M. Flynn, and D.A. Spiegel et al. Vancomycin prophylaxis of surgical site infection in clean orthopedic surgery Orthopedics 36 2013 138 146
30. Pahys J, Pahys JR, Cho SK, et al. Methods to decrease post-operative infections following posterior cervical spine surgery. Paper presented at: American Academy of Orthopaedic Surgeons 2011 Annual Meeting; February 16-19, 2011; San Diego, CA.