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Volumn 3, Issue 1, 2012, Pages

Fibroblast growth factor receptor 3 effects on proliferation and telomerase activity in sheep growth plate chondrocytes

Author keywords

Chondrocytes; Fibroblast growth factor receptor 3; Growth plate; Sheep; Telomerase; Thyroid hormone

Indexed keywords


EID: 84894451616     PISSN: 16749782     EISSN: 20491891     Source Type: Journal    
DOI: 10.1186/2049-1891-3-39     Document Type: Article
Times cited : (16)

References (46)
  • 2
    • 0024756977 scopus 로고
    • Endocrine and histologic correlates of the dynamics of the metacarpal growth plate in growing rams
    • Oberbauer AM, Currie WB, Krook L, Thonney ML. Endocrine and histologic correlates of the dynamics of the metacarpal growth plate in growing rams. J Anim Sci 1989, 67:3124-3135.
    • (1989) J Anim Sci , vol.67 , pp. 3124-3135
    • Oberbauer, A.M.1    Currie, W.B.2    Krook, L.3    Thonney, M.L.4
  • 3
    • 0029928791 scopus 로고    scopus 로고
    • Skeletal overgrowth and deafness in mice lacking fibroblast growth factor receptor 3
    • 10.1038/ng0496-390, 8630492
    • Colvin JS, Bohne BA, Harding GW, McEwen DG, Ornitz DM. Skeletal overgrowth and deafness in mice lacking fibroblast growth factor receptor 3. Nat Genet 1996, 12:390-397. 10.1038/ng0496-390, 8630492.
    • (1996) Nat Genet , vol.12 , pp. 390-397
    • Colvin, J.S.1    Bohne, B.A.2    Harding, G.W.3    McEwen, D.G.4    Ornitz, D.M.5
  • 4
    • 0029917507 scopus 로고    scopus 로고
    • Fibroblast growth factor receptor 3 is a negative regulator of bone growth
    • 10.1016/S0092-8674(00)81069-7, 8601314
    • Deng C, Wynshaw-Boris A, Zhou F, Kuo A, Leder P. Fibroblast growth factor receptor 3 is a negative regulator of bone growth. Cell 1996, 84:911-921. 10.1016/S0092-8674(00)81069-7, 8601314.
    • (1996) Cell , vol.84 , pp. 911-921
    • Deng, C.1    Wynshaw-Boris, A.2    Zhou, F.3    Kuo, A.4    Leder, P.5
  • 5
    • 0027964261 scopus 로고
    • Mutations in the transmembrane domain of FGFR3 cause the most common genetic form of dwarfism, achondroplasia
    • 10.1016/0092-8674(94)90302-6, 7913883
    • Shiang R, Thompson LM, Zhu YZ, Church DM, Fielder TJ, Bocian M, Winokur ST, Wasmuth JJ. Mutations in the transmembrane domain of FGFR3 cause the most common genetic form of dwarfism, achondroplasia. Cell 1994, 78:335-342. 10.1016/0092-8674(94)90302-6, 7913883.
    • (1994) Cell , vol.78 , pp. 335-342
    • Shiang, R.1    Thompson, L.M.2    Zhu, Y.Z.3    Church, D.M.4    Fielder, T.J.5    Bocian, M.6    Winokur, S.T.7    Wasmuth, J.J.8
  • 6
    • 33644884975 scopus 로고    scopus 로고
    • A single-base change in the tyrosine kinase II domain of ovine FGFR3 causes hereditary chondrodysplasia in sheep
    • 10.1111/j.1365-2052.2005.01398.x, 16441300
    • Beever JE, Smit MA, Meyers SN, Hadfield TS, Bottema C, Albretsen J, Cockett NE. A single-base change in the tyrosine kinase II domain of ovine FGFR3 causes hereditary chondrodysplasia in sheep. Anim Genet 2006, 37:66-71. 10.1111/j.1365-2052.2005.01398.x, 16441300.
    • (2006) Anim Genet , vol.37 , pp. 66-71
    • Beever, J.E.1    Smit, M.A.2    Meyers, S.N.3    Hadfield, T.S.4    Bottema, C.5    Albretsen, J.6    Cockett, N.E.7
  • 7
    • 33750580864 scopus 로고    scopus 로고
    • Enhanced skeletal growth of sheep heterozygous for an inactivated fibroblast growth factor receptor 3
    • 10.2527/jas.2006-255, 17032787
    • Smith LB, Dally MR, Sainz RD, Rodrigue KL, Oberbauer AM. Enhanced skeletal growth of sheep heterozygous for an inactivated fibroblast growth factor receptor 3. J Anim Sci 2006, 84:2942-2949. 10.2527/jas.2006-255, 17032787.
    • (2006) J Anim Sci , vol.84 , pp. 2942-2949
    • Smith, L.B.1    Dally, M.R.2    Sainz, R.D.3    Rodrigue, K.L.4    Oberbauer, A.M.5
  • 9
    • 0034772675 scopus 로고    scopus 로고
    • Differential regulation of endochondral bone growth and joint development by FGFR1 and FGFR3 tyrosine kinase domains
    • Wang Q, Green RP, Zhao G, Ornitz DM. Differential regulation of endochondral bone growth and joint development by FGFR1 and FGFR3 tyrosine kinase domains. Development 2001, 128:3867-3876.
    • (2001) Development , vol.128 , pp. 3867-3876
    • Wang, Q.1    Green, R.P.2    Zhao, G.3    Ornitz, D.M.4
  • 11
    • 83455244821 scopus 로고    scopus 로고
    • The skeleton: a multi-functional complex organ. The growth plate chondrocyte and endochondral ossification
    • 10.1530/JOE-11-0048, 21642379
    • Mackie EJ, Tatarczuch L, Mirams M. The skeleton: a multi-functional complex organ. The growth plate chondrocyte and endochondral ossification. J Endocrinol 2011, 211:109-121. 10.1530/JOE-11-0048, 21642379.
    • (2011) J Endocrinol , vol.211 , pp. 109-121
    • Mackie, E.J.1    Tatarczuch, L.2    Mirams, M.3
  • 13
    • 0027457447 scopus 로고
    • Determination of proliferative characteristics of growth plate chondrocytes by labeling with bromodeoxyuridine
    • 10.1007/BF00308319, 8443686
    • Farnum C, Wilsman N. Determination of proliferative characteristics of growth plate chondrocytes by labeling with bromodeoxyuridine. Calcif Tissue Int 1993, 52:110-119. 10.1007/BF00308319, 8443686.
    • (1993) Calcif Tissue Int , vol.52 , pp. 110-119
    • Farnum, C.1    Wilsman, N.2
  • 14
    • 0025731583 scopus 로고
    • Structure and function of telomeres
    • 10.1038/350569a0, 1708110
    • Blackburn EH. Structure and function of telomeres. Nature 1991, 350:569-573. 10.1038/350569a0, 1708110.
    • (1991) Nature , vol.350 , pp. 569-573
    • Blackburn, E.H.1
  • 15
    • 33745847778 scopus 로고    scopus 로고
    • Telomeres and telomerase biology in vertebrates: progress towards a non-human model for replicative senescence and ageing
    • 10.1007/s10522-005-4901-4, 16518699
    • Davis T, Kipling D. Telomeres and telomerase biology in vertebrates: progress towards a non-human model for replicative senescence and ageing. Biogerontology 2005, 6:371-385. 10.1007/s10522-005-4901-4, 16518699.
    • (2005) Biogerontology , vol.6 , pp. 371-385
    • Davis, T.1    Kipling, D.2
  • 16
    • 33745644489 scopus 로고    scopus 로고
    • Telomerase gene expression in the chicken: telomerase RNA (TR) and reverse transcriptase (TERT) transcript profiles are tissue-specific and correlate with telomerase activity
    • OHare T, Delany M. Telomerase gene expression in the chicken: telomerase RNA (TR) and reverse transcriptase (TERT) transcript profiles are tissue-specific and correlate with telomerase activity. Age 2005, 27:257-266.
    • (2005) Age , vol.27 , pp. 257-266
    • OHare, T.1    Delany, M.2
  • 17
    • 38949156672 scopus 로고    scopus 로고
    • TERT promotes epithelial proliferation through transcriptional control of a Myc- and Wnt-related developmental program
    • 10.1371/journal.pgen.0040010, 2211538, 18208333
    • Choi J, Southworth LK, Sarin KY, Venteicher AS, Ma W, Chang W, Cheung P, Jun S, Artandi MK, Shah N, et al. TERT promotes epithelial proliferation through transcriptional control of a Myc- and Wnt-related developmental program. PLoS Genet 2008, 4:e10. 10.1371/journal.pgen.0040010, 2211538, 18208333.
    • (2008) PLoS Genet , vol.4
    • Choi, J.1    Southworth, L.K.2    Sarin, K.Y.3    Venteicher, A.S.4    Ma, W.5    Chang, W.6    Cheung, P.7    Jun, S.8    Artandi, M.K.9    Shah, N.10
  • 18
    • 1542306071 scopus 로고    scopus 로고
    • Telomerase as a growth-promoting factor
    • 10.4161/cc.2.6.515, 14504469
    • Gorbunova V, Seluanov A. Telomerase as a growth-promoting factor. Cell Cycle 2003, 2:534-537. 10.4161/cc.2.6.515, 14504469.
    • (2003) Cell Cycle , vol.2 , pp. 534-537
    • Gorbunova, V.1    Seluanov, A.2
  • 19
    • 0038056347 scopus 로고    scopus 로고
    • Telomerase modulates expression of growth-controlling genes and enhances cell proliferation
    • 10.1038/ncb985, 12717449
    • Smith LL, Coller HA, Roberts JM. Telomerase modulates expression of growth-controlling genes and enhances cell proliferation. Nat Cell Biol 2003, 5:474-479. 10.1038/ncb985, 12717449.
    • (2003) Nat Cell Biol , vol.5 , pp. 474-479
    • Smith, L.L.1    Coller, H.A.2    Roberts, J.M.3
  • 20
    • 75649116087 scopus 로고    scopus 로고
    • Comparing effects of mTR and mTERT deletion on gene expression and DNA damage response: a critical examination of telomere length maintenance-independent roles of telomerase
    • 10.1093/nar/gkp855, 2800220, 19850716
    • Vidal-Cardenas SL, Greider CW. Comparing effects of mTR and mTERT deletion on gene expression and DNA damage response: a critical examination of telomere length maintenance-independent roles of telomerase. Nucleic Acids Res 2010, 38:60-71. 10.1093/nar/gkp855, 2800220, 19850716.
    • (2010) Nucleic Acids Res , vol.38 , pp. 60-71
    • Vidal-Cardenas, S.L.1    Greider, C.W.2
  • 21
    • 67449093864 scopus 로고    scopus 로고
    • NFX1-123 increases hTERT expression and telomerase activity posttranscriptionally in human papillomavirus type 16 E6 keratinocytes
    • 10.1128/JVI.02556-08, 2698580, 19369336
    • Katzenellenbogen RA, Vliet-Gregg P, Xu M, Galloway DA. NFX1-123 increases hTERT expression and telomerase activity posttranscriptionally in human papillomavirus type 16 E6 keratinocytes. J Virol 2009, 83:6446-6456. 10.1128/JVI.02556-08, 2698580, 19369336.
    • (2009) J Virol , vol.83 , pp. 6446-6456
    • Katzenellenbogen, R.A.1    Vliet-Gregg, P.2    Xu, M.3    Galloway, D.A.4
  • 22
    • 0036684533 scopus 로고    scopus 로고
    • Events in the immortalizing process of primary human mammary epithelial cells by the catalytic subunit of human telomerase
    • 1222721, 11978176
    • Kim H, Farris J, Christman SA, Kong B-W, Foster LK, OGrady SM, Foster DN. Events in the immortalizing process of primary human mammary epithelial cells by the catalytic subunit of human telomerase. Biochem J 2002, 365:765-772. 1222721, 11978176.
    • (2002) Biochem J , vol.365 , pp. 765-772
    • Kim, H.1    Farris, J.2    Christman, S.A.3    Kong, B.-W.4    Foster, L.K.5    OGrady, S.M.6    Foster, D.N.7
  • 24
    • 1942453312 scopus 로고    scopus 로고
    • Telomere length, telomerase activity, and expression of human telomerase reverse transcriptase mRNA in growth plate of epiphyseal articular cartilage in femoral head during normal human development and in thanatophoric dysplasia
    • 10.1016/j.humpath.2003.08.022, 15116319
    • Morita M, Nakanishi K, Kawai T, Fujikawa K. Telomere length, telomerase activity, and expression of human telomerase reverse transcriptase mRNA in growth plate of epiphyseal articular cartilage in femoral head during normal human development and in thanatophoric dysplasia. Hum Pathol 2004, 35:403-411. 10.1016/j.humpath.2003.08.022, 15116319.
    • (2004) Hum Pathol , vol.35 , pp. 403-411
    • Morita, M.1    Nakanishi, K.2    Kawai, T.3    Fujikawa, K.4
  • 25
    • 0029176674 scopus 로고
    • Fractionation of growth plate chondrocytes: differential expression of IGF-I and growth hormone and IGF-I receptor mRNA in purified populations
    • 10.3109/03008209509010809, 15609625
    • Oberbauer AM, Peng R. Fractionation of growth plate chondrocytes: differential expression of IGF-I and growth hormone and IGF-I receptor mRNA in purified populations. Connect Tissue Res 1995, 31:179-187. 10.3109/03008209509010809, 15609625.
    • (1995) Connect Tissue Res , vol.31 , pp. 179-187
    • Oberbauer, A.M.1    Peng, R.2
  • 26
    • 40949142856 scopus 로고    scopus 로고
    • Spatiotemporal localization of VEGF-A isoforms in the mouse postnatal growth plate
    • Evans KD, Oberbauer AM. Spatiotemporal localization of VEGF-A isoforms in the mouse postnatal growth plate. Anat Rec 2008, 291:6-13.
    • (2008) Anat Rec , vol.291 , pp. 6-13
    • Evans, K.D.1    Oberbauer, A.M.2
  • 27
    • 0032824874 scopus 로고    scopus 로고
    • Expression of the components of the insulin-like growth factor axis across the growth-plate
    • 10.1016/S0303-7207(99)00144-6, 10612424
    • Olney RC, Mougey EB. Expression of the components of the insulin-like growth factor axis across the growth-plate. Mol Cell Endocrinol 1999, 156:63-71. 10.1016/S0303-7207(99)00144-6, 10612424.
    • (1999) Mol Cell Endocrinol , vol.156 , pp. 63-71
    • Olney, R.C.1    Mougey, E.B.2
  • 29
    • 0029189923 scopus 로고
    • Growth hormone and IGF-I stimulate cell function in distinct zones of the rat epiphyseal growth plate
    • 10.3109/03008209509010810, 15609626
    • Oberbauer AM, Peng R. Growth hormone and IGF-I stimulate cell function in distinct zones of the rat epiphyseal growth plate. Connect Tissue Res 1995, 31:189-195. 10.3109/03008209509010810, 15609626.
    • (1995) Connect Tissue Res , vol.31 , pp. 189-195
    • Oberbauer, A.M.1    Peng, R.2
  • 30
    • 11144345697 scopus 로고    scopus 로고
    • Repair of articular cartilage defects treated by microfracture and a three-dimensional collagen matrix
    • 10.1016/j.biomaterials.2004.09.034, 15621252
    • Dorotka R, Windberger U, Macfelda K, Bindreiter U, Toma C, Nehrer S. Repair of articular cartilage defects treated by microfracture and a three-dimensional collagen matrix. Biomaterials 2005, 26:3617-3629. 10.1016/j.biomaterials.2004.09.034, 15621252.
    • (2005) Biomaterials , vol.26 , pp. 3617-3629
    • Dorotka, R.1    Windberger, U.2    Macfelda, K.3    Bindreiter, U.4    Toma, C.5    Nehrer, S.6
  • 31
    • 33846566729 scopus 로고    scopus 로고
    • Fibroblast growth factor expression in the postnatal growth plate
    • 10.1016/j.bone.2006.10.013, 17169623
    • Lazarus JE, Hegde A, Andrade AC, Nilsson O, Baron J. Fibroblast growth factor expression in the postnatal growth plate. Bone 2007, 40:577-586. 10.1016/j.bone.2006.10.013, 17169623.
    • (2007) Bone , vol.40 , pp. 577-586
    • Lazarus, J.E.1    Hegde, A.2    Andrade, A.C.3    Nilsson, O.4    Baron, J.5
  • 33
  • 34
    • 2442624561 scopus 로고    scopus 로고
    • Establishment of a real-time RT-PCR for the determination of absolute amounts of IGF-I and IGF-II gene expression in liver and extrahepatic sites of the tilapia
    • 10.1016/j.ygcen.2004.03.006, 15158131
    • Caelers A, Berishvili G, Meli ML, Eppler E, Reinecke M. Establishment of a real-time RT-PCR for the determination of absolute amounts of IGF-I and IGF-II gene expression in liver and extrahepatic sites of the tilapia. Gen Comp Endocrinol 2004, 137:196-204. 10.1016/j.ygcen.2004.03.006, 15158131.
    • (2004) Gen Comp Endocrinol , vol.137 , pp. 196-204
    • Caelers, A.1    Berishvili, G.2    Meli, M.L.3    Eppler, E.4    Reinecke, M.5
  • 35
    • 16644376117 scopus 로고    scopus 로고
    • Fluorimetric DNA assay of cell number
    • Otto WR. Fluorimetric DNA assay of cell number. Methods Mol Biol 2005, 289:251-262.
    • (2005) Methods Mol Biol , vol.289 , pp. 251-262
    • Otto, W.R.1
  • 36
    • 39049192615 scopus 로고    scopus 로고
    • SiRNA mediated knockdown of fibroblast growth factor receptors 1 or 3 inhibits FGF-induced anchorage-independent clonogenicity but does not affect MAPK activation
    • Estes NR, Thottassery JV, Kern FG. siRNA mediated knockdown of fibroblast growth factor receptors 1 or 3 inhibits FGF-induced anchorage-independent clonogenicity but does not affect MAPK activation. Oncol Rep 2006, 15:1407-1416.
    • (2006) Oncol Rep , vol.15 , pp. 1407-1416
    • Estes, N.R.1    Thottassery, J.V.2    Kern, F.G.3
  • 37
    • 51049096401 scopus 로고    scopus 로고
    • Identification and functional characterization of the human glutathione S-transferase P1 gene as a novel transcriptional target of the p53 tumor suppressor gene
    • 10.1158/1541-7786.MCR-07-2105, 2570202, 18505928
    • Lo HW, Stephenson L, Cao X, Milas M, Pollock R, Ali-Osman F. Identification and functional characterization of the human glutathione S-transferase P1 gene as a novel transcriptional target of the p53 tumor suppressor gene. Mol Cancer Res 2008, 6:843-850. 10.1158/1541-7786.MCR-07-2105, 2570202, 18505928.
    • (2008) Mol Cancer Res , vol.6 , pp. 843-850
    • Lo, H.W.1    Stephenson, L.2    Cao, X.3    Milas, M.4    Pollock, R.5    Ali-Osman, F.6
  • 38
    • 0026630526 scopus 로고
    • Effects of tri-iodothyronine and insulin-like growth factor-I (IGF-I) on alkaline phosphatase activity, [3H]thymidine incorporation and IGF-I receptor mRNA in cultured rat epiphyseal chondrocytes
    • 10.1677/joe.0.1350115, 1431676
    • Ohlsson C, Nilsson A, Lindahl A. Effects of tri-iodothyronine and insulin-like growth factor-I (IGF-I) on alkaline phosphatase activity, [3H]thymidine incorporation and IGF-I receptor mRNA in cultured rat epiphyseal chondrocytes. J Endocrinol 1992, 135:115-123. 10.1677/joe.0.1350115, 1431676.
    • (1992) J Endocrinol , vol.135 , pp. 115-123
    • Ohlsson, C.1    Nilsson, A.2    Lindahl, A.3
  • 39
    • 0034522252 scopus 로고    scopus 로고
    • Expression of cyclin-dependent kinase inhibitors in epiphyseal chondrocytes induced to terminally differentiate with thyroid hormone
    • 10.1210/en.141.12.4552, 11108267
    • Ballock RT, Zhou X, Mink LM, Chen DH, Mita BC, Stewart MC. Expression of cyclin-dependent kinase inhibitors in epiphyseal chondrocytes induced to terminally differentiate with thyroid hormone. Endocrinology 2000, 141:4552-4557. 10.1210/en.141.12.4552, 11108267.
    • (2000) Endocrinology , vol.141 , pp. 4552-4557
    • Ballock, R.T.1    Zhou, X.2    Mink, L.M.3    Chen, D.H.4    Mita, B.C.5    Stewart, M.C.6
  • 40
    • 0033697747 scopus 로고    scopus 로고
    • Thyroid hormones regulate hypertrophic chondrocyte differentiation and expression of parathyroid hormone-related peptide and its receptor during endochondral bone formation
    • 10.1359/jbmr.2000.15.12.2431, 11127207
    • Stevens DA, Hasserjian RP, Robson H, Siebler T, Shalet SM, Williams GR. Thyroid hormones regulate hypertrophic chondrocyte differentiation and expression of parathyroid hormone-related peptide and its receptor during endochondral bone formation. J Bone Miner Res 2000, 15:2431-2442. 10.1359/jbmr.2000.15.12.2431, 11127207.
    • (2000) J Bone Miner Res , vol.15 , pp. 2431-2442
    • Stevens, D.A.1    Hasserjian, R.P.2    Robson, H.3    Siebler, T.4    Shalet, S.M.5    Williams, G.R.6
  • 41
    • 0033752854 scopus 로고    scopus 로고
    • Thyroid hormone acts directly on growth plate chondrocytes to promote hypertrophic differentiation and inhibit clonal expansion and cell proliferation
    • 10.1210/en.141.10.3887, 11014246
    • Robson H, Siebler T, Stevens DA, Shalet SM, Williams GR. Thyroid hormone acts directly on growth plate chondrocytes to promote hypertrophic differentiation and inhibit clonal expansion and cell proliferation. Endocrinology 2000, 141:3887-3897. 10.1210/en.141.10.3887, 11014246.
    • (2000) Endocrinology , vol.141 , pp. 3887-3897
    • Robson, H.1    Siebler, T.2    Stevens, D.A.3    Shalet, S.M.4    Williams, G.R.5
  • 42
    • 0036712072 scopus 로고    scopus 로고
    • Human telomerase and its regulation
    • 10.1128/MMBR.66.3.407-425.2002, 120798, 12208997
    • Cong Y-S, Wright WE, Shay JW. Human telomerase and its regulation. Microbiol Mol Biol Rev 2002, 66:407-425. 10.1128/MMBR.66.3.407-425.2002, 120798, 12208997.
    • (2002) Microbiol Mol Biol Rev , vol.66 , pp. 407-425
    • Cong, Y.-S.1    Wright, W.E.2    Shay, J.W.3
  • 44
    • 36749064910 scopus 로고    scopus 로고
    • Telomere stability and telomerase in mesenchymal stem cells
    • 10.1016/j.biochi.2007.09.005, 18029083
    • Serakinci N, Graakjaer J, Kolvraa S. Telomere stability and telomerase in mesenchymal stem cells. Biochimie 2008, 90:33-40. 10.1016/j.biochi.2007.09.005, 18029083.
    • (2008) Biochimie , vol.90 , pp. 33-40
    • Serakinci, N.1    Graakjaer, J.2    Kolvraa, S.3
  • 45
    • 0032557555 scopus 로고    scopus 로고
    • Fibroblast growth factor receptor 3 mutations promote apoptosis but do not alter chondrocyte proliferation in thanatophoric dysplasia
    • 10.1074/jbc.273.21.13007, 9582336
    • Legeai-Mallet L, Benoist-Lasselin C, Delezoide A-L, Munnich A, Bonaventure J. Fibroblast growth factor receptor 3 mutations promote apoptosis but do not alter chondrocyte proliferation in thanatophoric dysplasia. J Biol Chem 1998, 273:13007-13014. 10.1074/jbc.273.21.13007, 9582336.
    • (1998) J Biol Chem , vol.273 , pp. 13007-13014
    • Legeai-Mallet, L.1    Benoist-Lasselin, C.2    Delezoide, A.-L.3    Munnich, A.4    Bonaventure, J.5
  • 46
    • 77953914542 scopus 로고    scopus 로고
    • The effect of telomerase template antagonist GRN163L on bone-marrow-derived Rat mesenchymal stem cells is reversible and associated with altered expression of cyclin d1, cdk4 and cdk6
    • Online First epub.
    • Tokcaer-Keskin Z, Dikmen ZG, Ayaloglu-Butun F, Gultekin S, Gryaznov SM, Akcali KC. The effect of telomerase template antagonist GRN163L on bone-marrow-derived Rat mesenchymal stem cells is reversible and associated with altered expression of cyclin d1, cdk4 and cdk6. Stem Cell Rev 2010, Online First epub.
    • (2010) Stem Cell Rev
    • Tokcaer-Keskin, Z.1    Dikmen, Z.G.2    Ayaloglu-Butun, F.3    Gultekin, S.4    Gryaznov, S.M.5    Akcali, K.C.6


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