GNAS sequencing identifies IPMN-specific mutations in a subgroup of diminutive pancreatic cysts referred to as "Incipient IPMNs"

American Journal of Surgical Pathology

Volumn 38, Issue 3, 2014, Pages 360-363

  Matthaei, Hanno ^a,c   Wu, Jian ^a   Dal Molin, Marco ^a   Shi, Chanjuan ^b   Perner, Sven ^c   Kristiansen, Glen ^c   Lingohr, Philipp ^c   Kalff, Jörg C ^c   Wolfgang, Christopher L ^a   Kinzler, Kenneth W ^a   Vogelstein, Bert ^a   Maitra, Anirban ^a   Hruban, Ralph H ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

^c UNIVERSITY OF BONN   (Germany)

Author keywords

GNAS mutation; incipient IPMN; intraductal papillary mucinous neoplasm; pancreatic cyst

Indexed keywords

GNAS PROTEIN, HUMAN; STIMULATORY GUANINE NUCLEOTIDE BINDING PROTEIN; TUMOR MARKER;

ADULT; AGED; ARTICLE; CANCER GRADING; CLASSIFICATION; DIFFERENTIAL DIAGNOSIS; FEMALE; GENETIC PREDISPOSITION; GENETIC SCREENING; GENETICS; HUMAN; MALE; METHODOLOGY; MIDDLE AGED; MULTICENTER STUDY; MUTATION; NEOPLASM; NUCLEOTIDE SEQUENCE; PANCREAS CARCINOMA; PANCREAS CYST; PANCREAS TUMOR; PAPILLARY CARCINOMA; PATHOLOGY; PHENOTYPE; PREDICTIVE VALUE; SWITZERLAND; TUMOR VOLUME; UNITED STATES;

ADULT; AGED; CARCINOMA, PANCREATIC DUCTAL; CARCINOMA, PAPILLARY; DIAGNOSIS, DIFFERENTIAL; DNA MUTATIONAL ANALYSIS; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GENETIC TESTING; GTP-BINDING PROTEIN ALPHA SUBUNITS, GS; HUMANS; MALE; MIDDLE AGED; MUTATION; NEOPLASM GRADING; NEOPLASMS, CYSTIC, MUCINOUS, AND SEROUS; PANCREATIC CYST; PANCREATIC NEOPLASMS; PHENOTYPE; PREDICTIVE VALUE OF TESTS; SWITZERLAND; TUMOR BURDEN; TUMOR MARKERS, BIOLOGICAL; UNITED STATES;

EID: 84894438827     PISSN: 01475185     EISSN: 15320979     Source Type: Journal    
DOI: 10.1097/PAS.0000000000000117     Document Type: Article

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