Comparison of five peptide vectors for improved brain delivery of the lysosomal enzyme arylsulfatase A

Journal of Neuroscience

Volumn 34, Issue 9, 2014, Pages 3122-3129

  Böckenhoff, Annika ^a   Cramer, Sandra ^b   Wölte, Philipp ^b   Knieling, Simeon ^a   Wohlenberg, Claudia ^a   Gieselmann, Volkmar ^a   Galla, Hans Joachim ^b   Matzner, Ulrich ^a  

^a UNIVERSITY OF BONN   (Germany)

^b UNIVERSITY OF MÜNSTER   (Germany)

Author keywords

Arylsulfatase A; Blood brain barrier; Enzyme replacement therapy; Lysosomal storage disease; Metachromatic leukodystrophy; Peptide vectors

Indexed keywords

ANGIOPOIETIN 2; APOLIPOPROTEIN B; APOLIPOPROTEIN E; APOLIPOPROTEIN E2; CEREBROSIDE SULFATASE; HYBRID PROTEIN; LOW DENSITY LIPOPROTEIN RECEPTOR RELATED PROTEIN; SOMATOMEDIN B RECEPTOR; TRANSACTIVATOR PROTEIN;

ANIMAL CELL; ARTICLE; BLOOD BRAIN BARRIER; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; ENDOCYTOSIS; ENZYME REPLACEMENT; EXPRESSION VECTOR; FEMALE; INTERNALIZATION; LYSOSOME STORAGE DISEASE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN LOCALIZATION; WESTERN BLOTTING;

ARYLSULFATASE A; BLOOD-BRAIN BARRIER; ENZYME REPLACEMENT THERAPY; LYSOSOMAL STORAGE DISEASE; METACHROMATIC LEUKODYSTROPHY; PEPTIDE VECTORS;

ANIMALS; APOLIPOPROTEINS E; BLOOD-BRAIN BARRIER; BRAIN; CELLS, CULTURED; CEREBROSIDE-SULFATASE; CRICETULUS; CULTURE MEDIA, CONDITIONED; DISEASE MODELS, ANIMAL; ENDOTHELIAL CELLS; FEMALE; GENETIC VECTORS; HUMANS; LEUKODYSTROPHY, METACHROMATIC; MALE; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; PEPTIDES; RECEPTOR, IGF TYPE 2; RECOMBINANT FUSION PROTEINS;

EID: 84894433216     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.4785-13.2014     Document Type: Article

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