Site-specific analysis of N-linked oligosaccharides of recombinant lysosomal arylsulfatase A produced in different cell lines

Glycobiology

Volumn 20, Issue 2, 2009, Pages 248-259

  Schröder, Stephan ^a   Matthes, Frank ^a   Hyden, Pia ^b   Andersson, Claes ^b   Fogh, Jens ^b   Müller Loennies, Sven ^c   Braulke, Thomas ^d   Gieselmann, Volkmar ^a   Matzner, Ulrich ^a  

^a UNIVERSITY OF BONN   (Germany)

^b Zymenex A/S   (Sweden)

^c RESEARCH CENTER BORSTEL   (Germany)

^d UNIVERSITY OF HAMBURG   (Germany)

Author keywords

Arylsulfatase A; Enzyme replacement therapy; Mannose 6 phosphate; Metachromatic leukodystrophy

Indexed keywords

MANNOSE; MANNOSE 6 PHOSPHATE; OLIGOSACCHARIDE; RECOMBINANT ENZYME; RECOMBINANT LYSOSOMAL ARYLSULFATASE A; UNCLASSIFIED DRUG; CEREBROSIDE SULFATASE; RECOMBINANT PROTEIN;

ANIMAL CELL; ARTICLE; BIOREACTOR; CANCER CELL CULTURE; CELL STRAIN BHK; CONTROLLED STUDY; DRUG SYNTHESIS; ENZYME ANALYSIS; ENZYME REPLACEMENT; ENZYME STRUCTURE; FIBROSARCOMA; FUCOSYLATION; GLYCOSYLATION; HUMAN; HUMAN CELL; METACHROMATIC LEUKODYSTROPHY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; ANIMAL; BIOSYNTHESIS; CELL CULTURE; CHEMISTRY; CHO CELL; CRICETULUS; ENZYMOLOGY; HAMSTER; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; ISOLATION AND PURIFICATION; LYSOSOME; MASS SPECTROMETRY; METABOLISM;

ANIMALS; CELLS, CULTURED; CEREBROSIDE-SULFATASE; CHO CELLS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CRICETINAE; CRICETULUS; HUMANS; LYSOSOMES; OLIGOSACCHARIDES; RECOMBINANT PROTEINS; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION;

EID: 77649219919     PISSN: 09596658     EISSN: 14602423     Source Type: Journal    
DOI: 10.1093/glycob/cwp171     Document Type: Article

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