메뉴 건너뛰기




Volumn 10, Issue 2, 2014, Pages 243-256

Autophagy activation reduces renal tubular injury induced by urinary proteins

Author keywords

Apoptosis; Autophagic activation; Autophagic pathway; Tubular epithelial cells; Urinary proteins

Indexed keywords

BECLIN 1; CHLOROQUINE; NEUTROPHIL GELATINASE ASSOCIATED LIPOCALIN; PROTEIN P62; RAPAMYCIN; REACTIVE OXYGEN METABOLITE; SMALL INTERFERING RNA;

EID: 84894426170     PISSN: 15548627     EISSN: 15548635     Source Type: Journal    
DOI: 10.4161/auto.27004     Document Type: Article
Times cited : (82)

References (44)
  • 1
    • 36249025723 scopus 로고    scopus 로고
    • Autophagy: Process and function
    • PMID:18006683
    • Mizushima N. Autophagy: process and function. Genes Dev 2007; 21:2861-73; PMID:18006683; http://dx.doi.org/10.1101/gad.1599207
    • (2007) Genes Dev , vol.21 , pp. 2861-2873
    • Mizushima, N.1
  • 3
    • 34250826506 scopus 로고    scopus 로고
    • Autophagy in a mouse model of distal myopathy with rimmed vacuoles or hereditary inclusion body myopathy
    • PMID:17471014
    • Malicdan MC, Noguchi S, Nishino I. Autophagy in a mouse model of distal myopathy with rimmed vacuoles or hereditary inclusion body myopathy. Autophagy 2007; 3:396-8; PMID:17471014
    • (2007) Autophagy , vol.3 , pp. 396-398
    • Malicdan, M.C.1    Noguchi, S.2    Nishino, I.3
  • 6
    • 72549093841 scopus 로고    scopus 로고
    • Cardiomyocyte autophagy: Remodeling, repairing, and reconstructing the heart
    • PMID:19895751
    • Cao DJ, Gillette TG, Hill JA. Cardiomyocyte autophagy: remodeling, repairing, and reconstructing the heart. Curr Hypertens Rep 2009; 11:406-11; PMID:19895751; http://dx.doi.org/10.1007/s11906-009-0070-1
    • (2009) Curr Hypertens Rep , vol.11 , pp. 406-411
    • Cao, D.J.1    Gillette, T.G.2    Hill, J.A.3
  • 8
    • 44949102384 scopus 로고    scopus 로고
    • Autophagy is associated with apoptosis in cisplatin injury to renal tubular epithelial cells
    • PMID:18256309
    • Yang C, Kaushal V, Shah SV, Kaushal GP. Autophagy is associated with apoptosis in cisplatin injury to renal tubular epithelial cells. Am J Physiol Renal Physiol 2008; 294:F777-87; PMID:18256309; http://dx.doi.org/10.1152/ ajprenal.00590.2007
    • (2008) Am J Physiol Renal Physiol , vol.294
    • Yang, C.1    Kaushal, V.2    Shah, S.V.3    Kaushal, G.P.4
  • 9
    • 48249093820 scopus 로고    scopus 로고
    • Autophagy delays apoptosis in renal tubular epithelial cells in cisplatin cytotoxicity
    • PMID:18497570
    • Kaushal GP, Kaushal V, Herzog C, Yang C. Autophagy delays apoptosis in renal tubular epithelial cells in cisplatin cytotoxicity. Autophagy 2008; 4:710-2; PMID:18497570
    • (2008) Autophagy , vol.4 , pp. 710-712
    • Kaushal, G.P.1    Kaushal, V.2    Herzog, C.3    Yang, C.4
  • 10
    • 49749120592 scopus 로고    scopus 로고
    • Autophagy is cytoprotective during cisplatin injury of renal proximal tubular cells
    • PMID:18509315
    • Periyasamy-Thandavan S, Jiang M, Wei Q, Smith R, Yin XM, Dong Z. Autophagy is cytoprotective during cisplatin injury of renal proximal tubular cells. Kidney Int 2008; 74:631-40; PMID:18509315; http://dx.doi.org/10.1038/ki. 2008.214
    • (2008) Kidney Int , vol.74 , pp. 631-640
    • Periyasamy-Thandavan, S.1    Jiang, M.2    Wei, Q.3    Smith, R.4    Yin, X.M.5    Dong, Z.6
  • 11
    • 0032987767 scopus 로고    scopus 로고
    • Proteinuria induces tubular cell turnover: A potential mechanism for tubular atrophy
    • PMID:10027925
    • Thomas ME, Brunskill NJ, Harris KP, Bailey E, Pringle JH, Furness PN, Walls J. Proteinuria induces tubular cell turnover: A potential mechanism for tubular atrophy. Kidney Int 1999; 55:890-8; PMID:10027925; http://dx.doi.org/10. 1046/j.1523-1755.1999.055003890.x
    • (1999) Kidney Int , vol.55 , pp. 890-898
    • Thomas, M.E.1    Brunskill, N.J.2    Harris, K.P.3    Bailey, E.4    Pringle, J.H.5    Furness, P.N.6    Walls, J.7
  • 12
    • 1142275261 scopus 로고    scopus 로고
    • Mechanisms of tubulointerstitial injury in the kidney: Final common pathways to end-stage renal failure
    • PMID:14964574
    • Nangaku M. Mechanisms of tubulointerstitial injury in the kidney: final common pathways to end-stage renal failure. Intern Med 2004; 43:9-17; PMID:14964574; http://dx.doi.org/10.2169/internalmedicine.43.9
    • (2004) Intern Med , vol.43 , pp. 9-17
    • Nangaku, M.1
  • 13
    • 0036235016 scopus 로고    scopus 로고
    • Protein overload-induced NF-kappaB activation in proximal tubular cells requires H(2)O(2) through a PKC-dependent pathway
    • PMID:11961005
    • Morigi M, Macconi D, Zoja C, Donadelli R, Buelli S, Zanchi C, Ghilardi M, Remuzzi G. Protein overload-induced NF-kappaB activation in proximal tubular cells requires H(2)O(2) through a PKC-dependent pathway. J Am Soc Nephrol 2002; 13:1179-89; PMID:11961005
    • (2002) J Am Soc Nephrol , vol.13 , pp. 1179-1189
    • Morigi, M.1    Macconi, D.2    Zoja, C.3    Donadelli, R.4    Buelli, S.5    Zanchi, C.6    Ghilardi, M.7    Remuzzi, G.8
  • 14
    • 34047212211 scopus 로고    scopus 로고
    • Mitochondria are the major targets in albumin-induced apoptosis in proximal tubule cells
    • PMID:17360944
    • Erkan E, Devarajan P, Schwartz GJ. Mitochondria are the major targets in albumin-induced apoptosis in proximal tubule cells. J Am Soc Nephrol 2007; 18:1199-208; PMID:17360944; http://dx.doi.org/10.1681/ASN.2006040407
    • (2007) J Am Soc Nephrol , vol.18 , pp. 1199-1208
    • Erkan, E.1    Devarajan, P.2    Schwartz, G.J.3
  • 16
    • 34247186472 scopus 로고    scopus 로고
    • Reactive oxygen species are essential for autophagy and specifically regulate the activity of Atg4
    • PMID:17347651
    • Scherz-Shouval R, Shvets E, Fass E, Shorer H, Gil L, Elazar Z. Reactive oxygen species are essential for autophagy and specifically regulate the activity of Atg4. EMBO J 2007; 26:1749-60; PMID:17347651; http://dx.doi.org/10. 1038/sj.emboj.7601623
    • (2007) EMBO J , vol.26 , pp. 1749-1760
    • Scherz-Shouval, R.1    Shvets, E.2    Fass, E.3    Shorer, H.4    Gil, L.5    Elazar, Z.6
  • 17
    • 33749579383 scopus 로고    scopus 로고
    • Endoplasmic reticulum stress triggers autophagy
    • PMID:16901900
    • Yorimitsu T, Nair U, Yang Z, Klionsky DJ. Endoplasmic reticulum stress triggers autophagy. J Biol Chem 2006; 281:30299-304; PMID:16901900; http://dx.doi.org/10.1074/jbc.M607007200
    • (2006) J Biol Chem , vol.281 , pp. 30299-30304
    • Yorimitsu, T.1    Nair, U.2    Yang, Z.3    Klionsky, D.J.4
  • 18
    • 34548077575 scopus 로고    scopus 로고
    • Dissection of the autophagosome maturation process by a novel reporter protein, tandem fluorescent-tagged LC3
    • PMID:17534139
    • Kimura S, Noda T, Yoshimori T. Dissection of the autophagosome maturation process by a novel reporter protein, tandem fluorescent-tagged LC3. Autophagy 2007; 3:452-60; PMID:17534139
    • (2007) Autophagy , vol.3 , pp. 452-460
    • Kimura, S.1    Noda, T.2    Yoshimori, T.3
  • 20
    • 84862273857 scopus 로고    scopus 로고
    • Monitoring autophagic flux by an improved tandem fluorescent-tagged LC3 (mTagRFP-mWasabi-LC3) reveals that high-dose rapamycin impairs autophagic flux in cancer cells
    • PMID:22647982
    • Zhou C, Zhong W, Zhou J, Sheng F, Fang Z, Wei Y, Chen Y, Deng X, Xia B, Lin J. Monitoring autophagic flux by an improved tandem fluorescent-tagged LC3 (mTagRFP-mWasabi-LC3) reveals that high-dose rapamycin impairs autophagic flux in cancer cells. Autophagy 2012; 8:1215-26; PMID:22647982; http://dx.doi.org/10. 4161/auto.20284
    • (2012) Autophagy , vol.8 , pp. 1215-1226
    • Zhou, C.1    Zhong, W.2    Zhou, J.3    Sheng, F.4    Fang, Z.5    Wei, Y.6    Chen, Y.7    Deng, X.8    Xia, B.9    Lin, J.10
  • 23
    • 77951248828 scopus 로고    scopus 로고
    • Autophagy: Links with the proteasome
    • PMID:19962293
    • Lamark T, Johansen T. Autophagy: links with the proteasome. Curr Opin Cell Biol 2010; 22:192-8; PMID:19962293; http://dx.doi.org/10.1016/j.ceb.2009. 11.002
    • (2010) Curr Opin Cell Biol , vol.22 , pp. 192-198
    • Lamark, T.1    Johansen, T.2
  • 24
    • 75749122303 scopus 로고    scopus 로고
    • Methods in mammalian autophagy research
    • PMID:20144757
    • Mizushima N, Yoshimori T, Levine B. Methods in mammalian autophagy research. Cell 2010; 140:313-26; PMID:20144757; http://dx.doi.org/10.1016/j. cell.2010.01.028
    • (2010) Cell , vol.140 , pp. 313-326
    • Mizushima, N.1    Yoshimori, T.2    Levine, B.3
  • 25
    • 0035032723 scopus 로고    scopus 로고
    • Beclinphosphatidylinositol 3-kinase complex functions at the trans - Golgi network
    • PMID:11306555
    • Kihara A, Kabeya Y, Ohsumi Y, Yoshimori T. Beclinphosphatidylinositol 3-kinase complex functions at the trans - Golgi network. EMBO Rep 2001; 2:330-5; PMID:11306555; http://dx.doi.org/10.1093/embo-reports/kve061
    • (2001) EMBO Rep , vol.2 , pp. 330-335
    • Kihara, A.1    Kabeya, Y.2    Ohsumi, Y.3    Yoshimori, T.4
  • 26
    • 0000906170 scopus 로고    scopus 로고
    • Induction of autophagy and inhibition of tumorigenesis by beclin 1
    • PMID:10604474
    • Liang XH, Jackson S, Seaman M, Brown K, Kempkes B, Hibshoosh H, Levine B. Induction of autophagy and inhibition of tumorigenesis by beclin 1. Nature 1999; 402:672-6; PMID:10604474; http://dx.doi.org/10.1038/45257
    • (1999) Nature , vol.402 , pp. 672-676
    • Liang, X.H.1    Jackson, S.2    Seaman, M.3    Brown, K.4    Kempkes, B.5    Hibshoosh, H.6    Levine, B.7
  • 27
    • 79961122410 scopus 로고    scopus 로고
    • Regulation of autophagy by lysosomal positioning
    • PMID:21521941
    • Korolchuk VI, Rubinsztein DC. Regulation of autophagy by lysosomal positioning. Autophagy 2011; 7:927-8; PMID:21521941; http://dx.doi.org/10.4161/ auto.7.8.15862
    • (2011) Autophagy , vol.7 , pp. 927-928
    • Korolchuk, V.I.1    Rubinsztein, D.C.2
  • 28
    • 84856044276 scopus 로고    scopus 로고
    • Aristolochic acid I induced autophagy extenuates cell apoptosis via ERK 1/2 pathway in renal tubular epithelial cells
    • PMID:22276178
    • Zeng Y, Yang X, Wang J, Fan J, Kong Q, Yu X. Aristolochic acid I induced autophagy extenuates cell apoptosis via ERK 1/2 pathway in renal tubular epithelial cells. PLoS One 2012; 7:e30312; PMID:22276178; http://dx.doi.org/10. 1371/journal.pone.0030312
    • (2012) PLoS One , vol.7
    • Zeng, Y.1    Yang, X.2    Wang, J.3    Fan, J.4    Kong, Q.5    Yu, X.6
  • 31
    • 56349138968 scopus 로고    scopus 로고
    • DAP-kinase is a mediator of endoplasmic reticulum stress-induced caspase activation and autophagic cell death
    • PMID:18806755
    • Gozuacik D, Bialik S, Raveh T, Mitou G, Shohat G, Sabanay H, Mizushima N, Yoshimori T, Kimchi A. DAP-kinase is a mediator of endoplasmic reticulum stress-induced caspase activation and autophagic cell death. Cell Death Differ 2008; 15:1875-86; PMID:18806755; http://dx.doi.org/10.1038/cdd.2008.121
    • (2008) Cell Death Differ , vol.15 , pp. 1875-1886
    • Gozuacik, D.1    Bialik, S.2    Raveh, T.3    Mitou, G.4    Shohat, G.5    Sabanay, H.6    Mizushima, N.7    Yoshimori, T.8    Kimchi, A.9
  • 32
    • 68049104247 scopus 로고    scopus 로고
    • Autophagy: Molecular machinery, regulation, and implications for renal pathophysiology
    • PMID:19279132
    • Periyasamy-Thandavan S, Jiang M, Schoenlein P, Dong Z. Autophagy: molecular machinery, regulation, and implications for renal pathophysiology. Am J Physiol Renal Physiol 2009; 297:F244-56; PMID:19279132; http://dx.doi.org/10. 1152/ajprenal.00033.2009
    • (2009) Am J Physiol Renal Physiol , vol.297
    • Periyasamy-Thandavan, S.1    Jiang, M.2    Schoenlein, P.3    Dong, Z.4
  • 33
    • 0037200266 scopus 로고    scopus 로고
    • Tubular apoptosis in the pathophysiology of renal disease
    • PMID:12602110
    • Hauser P, Oberbauer R. Tubular apoptosis in the pathophysiology of renal disease. Wien Klin Wochenschr 2002; 114:671-7; PMID:12602110
    • (2002) Wien Klin Wochenschr , vol.114 , pp. 671-677
    • Hauser, P.1    Oberbauer, R.2
  • 34
    • 0037371608 scopus 로고    scopus 로고
    • Mechanisms of renal cell repair and regeneration after acute renal failure
    • PMID:12604664
    • Nony PA, Schnellmann RG. Mechanisms of renal cell repair and regeneration after acute renal failure. J Pharmacol Exp Ther 2003; 304:905-12; PMID:12604664; http://dx.doi.org/10.1124/jpet.102.035022
    • (2003) J Pharmacol Exp Ther , vol.304 , pp. 905-912
    • Nony, P.A.1    Schnellmann, R.G.2
  • 35
    • 84879461350 scopus 로고    scopus 로고
    • Molecular markers of kidney injury
    • PMID:21723753
    • Lane BR. Molecular markers of kidney injury. Urol Oncol 2013; 31:682-5; PMID:21723753; http://dx.doi.org/10.1016/j.urolonc.2011.05.007
    • (2013) Urol Oncol , vol.31 , pp. 682-685
    • Lane, B.R.1
  • 36
    • 33750736645 scopus 로고    scopus 로고
    • How does proteinuria cause progressive renal damage?
    • PMID:17035611
    • Abbate M, Zoja C, Remuzzi G. How does proteinuria cause progressive renal damage? J Am Soc Nephrol 2006; 17:2974-84; PMID:17035611; http://dx.doi.org/10. 1681/ASN.2006040377
    • (2006) J Am Soc Nephrol , vol.17 , pp. 2974-2984
    • Abbate, M.1    Zoja, C.2    Remuzzi, G.3
  • 37
    • 1642350993 scopus 로고    scopus 로고
    • Cellular responses to protein overload: Key event in renal disease progression
    • PMID:15090857
    • Zoja C, Benigni A, Remuzzi G. Cellular responses to protein overload: key event in renal disease progression. Curr Opin Nephrol Hypertens 2004; 13:31-7; PMID:15090857; http://dx.doi.org/10.1097/00041552-200401000-00005
    • (2004) Curr Opin Nephrol Hypertens , vol.13 , pp. 31-37
    • Zoja, C.1    Benigni, A.2    Remuzzi, G.3
  • 38
    • 27744489524 scopus 로고    scopus 로고
    • Rapamycin ameliorates proteinuria-associated tubulointerstitial inflammation and fibrosis in experimental membranous nephropathy
    • PMID:15917339
    • Bonegio RG, Fuhro R, Wang Z, Valeri CR, Andry C, Salant DJ, Lieberthal W. Rapamycin ameliorates proteinuria-associated tubulointerstitial inflammation and fibrosis in experimental membranous nephropathy. J Am Soc Nephrol 2005; 16:2063-72; PMID:15917339; http://dx.doi.org/10.1681/ASN.2004030180
    • (2005) J Am Soc Nephrol , vol.16 , pp. 2063-2072
    • Bonegio, R.G.1    Fuhro, R.2    Wang, Z.3    Valeri, C.R.4    Andry, C.5    Salant, D.J.6    Lieberthal, W.7
  • 39
    • 79951674629 scopus 로고    scopus 로고
    • mTOR and rapamycin in the kidney: Signaling and therapeutic implications beyond immunosuppression
    • PMID:21085109
    • Huber TB, Walz G, Kuehn EW. mTOR and rapamycin in the kidney: signaling and therapeutic implications beyond immunosuppression. Kidney Int 2011; 79:502-11; PMID:21085109; http://dx.doi.org/10.1038/ki.2010.457
    • (2011) Kidney Int , vol.79 , pp. 502-511
    • Huber, T.B.1    Walz, G.2    Kuehn, E.W.3
  • 40
    • 84862833325 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transdifferentiation of renal tubular epithelial cells induced by urinary proteins requires the activation of PKC-α and βI isozymes
    • PMID:21323641
    • Tang R, Yang C, Tao JL, You YK, An N, Li SM, Wu HL, Liu HF. Epithelial-mesenchymal transdifferentiation of renal tubular epithelial cells induced by urinary proteins requires the activation of PKC-α and βI isozymes. Cell Biol Int 2011; 35:953-9; PMID:21323641; http://dx.doi.org/10. 1042/CBI20100668
    • (2011) Cell Biol Int , vol.35 , pp. 953-959
    • Tang, R.1    Yang, C.2    Tao, J.L.3    You, Y.K.4    An, N.5    Li, S.M.6    Wu, H.L.7    Liu, H.F.8
  • 41
    • 33845186387 scopus 로고    scopus 로고
    • Preparation and suppressive effect of astragalus polysaccharide in glomerulonephritis rats
    • PMID:17161813
    • Li S, Zhang Y, Zhao J. Preparation and suppressive effect of astragalus polysaccharide in glomerulonephritis rats. Int Immunopharmacol 2007; 7:23-8; PMID:17161813; http://dx.doi.org/10.1016/j.intimp.2006.08.016
    • (2007) Int Immunopharmacol , vol.7 , pp. 23-28
    • Li, S.1    Zhang, Y.2    Zhao, J.3
  • 42
    • 84862944057 scopus 로고    scopus 로고
    • Dipeptidyl peptidase IV inhibitor attenuates kidney injury in streptozotocin-induced diabetic rats
    • PMID:22025647
    • Liu WJ, Xie SH, Liu YN, Kim W, Jin HY, Park SK, Shao YM, Park TS. Dipeptidyl peptidase IV inhibitor attenuates kidney injury in streptozotocin-induced diabetic rats. J Pharmacol Exp Ther 2012; 340:248-55; PMID:22025647; http://dx.doi.org/10.1124/jpet.111.186866
    • (2012) J Pharmacol Exp Ther , vol.340 , pp. 248-255
    • Liu, W.J.1    Xie, S.H.2    Liu, Y.N.3    Kim, W.4    Jin, H.Y.5    Park, S.K.6    Shao, Y.M.7    Park, T.S.8
  • 43
    • 26844531363 scopus 로고    scopus 로고
    • Maturation of autophagic vacuoles in Mammalian cells
    • PMID:16874026
    • Eskelinen EL. Maturation of autophagic vacuoles in Mammalian cells. Autophagy 2005; 1:1-10; PMID:16874026; http://dx.doi.org/10.4161/auto.1.1.1270
    • (2005) Autophagy , vol.1 , pp. 1-10
    • Eskelinen, E.L.1
  • 44
    • 84872033874 scopus 로고    scopus 로고
    • Murraya koenigii leaf extract inhibits proteasome activity and induces cell death in breast cancer cells
    • PMID:23302496
    • Noolu B, Ajumeera R, Chauhan A, Nagalla B, Manchala R, Ismail A. Murraya koenigii leaf extract inhibits proteasome activity and induces cell death in breast cancer cells. BMC Complement Altern Med 2013; 13:7; PMID:23302496; http://dx.doi.org/10.1186/1472-6882-13-7
    • (2013) BMC Complement Altern Med , vol.13 , pp. 7
    • Noolu, B.1    Ajumeera, R.2    Chauhan, A.3    Nagalla, B.4    Manchala, R.5    Ismail, A.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.