Cytokine profile in cervical mucosa of Japanese patients with cervical intraepithelial neoplasia

International Journal of Clinical Oncology

Volumn 20, Issue 1, 2015, Pages 126-133

  Iwata, Takashi ^a   Fujii, Takuma ^a,b   Morii, Kenji ^c   Saito, Miyuki ^a   Sugiyama, Juri ^a   Nishio, Hiroshi ^a   Morisada, Tohru ^a   Tanaka, Kyoko ^a   Yaguchi, Tomonori ^c   Kawakami, Yutaka ^c   Aoki, Daisuke ^a  

^a KEIO UNIVERSITY   (Japan)

^b FUJITA HEALTH UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c KEIO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Cigarette smoking; CIN; Cytokine; Cytology; HPV

Indexed keywords

INTERLEUKIN 1BETA; INTERLEUKIN 8; MACROPHAGE INFLAMMATORY PROTEIN 1BETA;

ADULT; ASIAN CONTINENTAL ANCESTRY GROUP; DISEASE COURSE; FEMALE; HUMAN; IMMUNOLOGY; MUCOSA; PAPILLOMAVIRUS INFECTION; PATHOLOGY; SMOKING; SQUAMOUS INTRAEPITHELIAL LESION OF THE CERVIX; UTERINE CERVIX CARCINOMA IN SITU; UTERINE CERVIX TUMOR;

ADULT; ASIAN CONTINENTAL ANCESTRY GROUP; CERVICAL INTRAEPITHELIAL NEOPLASIA; CHEMOKINE CCL4; DISEASE PROGRESSION; FEMALE; HUMANS; INTERLEUKIN-1BETA; INTERLEUKIN-8; MUCOUS MEMBRANE; PAPILLOMAVIRUS INFECTIONS; SMOKING; SQUAMOUS INTRAEPITHELIAL LESIONS OF THE CERVIX; UTERINE CERVICAL NEOPLASMS;

EID: 84894359336     PISSN: 13419625     EISSN: 14377772     Source Type: Journal    
DOI: 10.1007/s10147-014-0680-8     Document Type: Article

References (40)

1. zur Hausen H (1989) Papillomaviruses in anogenital cancer as a model to understand the role of viruses in human cancers. Cancer Res 49:4677–4681
2. Rodriguez AC, Schiffman M, Herrero R et al (2008) Rapid clearance of human papillomavirus and implications for clinical focus on persistent infections. J Natl Cancer Inst 100:513–517
3. Ostor AG (1993) Natural history of cervical intraepithelial neoplasia: a critical review. Int J Gynecol Pathol 12:186–192
4. Melnikow J, Nuovo J, Willan AR et al (1998) Natural history of cervical squamous intraepithelial lesions: a meta-analysis. Obstet Gynecol 92:727–735
5. Holowaty P, Miller AB, Rohan T (1999) Natural history of dysplasia of the uterine cervix. J Natl Cancer Inst 91:252–258
6. Guzman-Olea E, Bermudez-Morales VH, Peralta-Zaragoza O et al (2012) Molecular mechanism and potential targets for blocking HPV-induced lesion development. J Oncol. doi:10.1155/2012/278312
7. Herman L, Hubert P, Herfs M et al (2010) The L1 major capsid protein of HPV16 differentially modulates APC trafficking according to the vaccination or natural infection context. Eur J Immunol 40:3075–3084
8. Nees M, Geoghegan JM, Hyman T et al (2001) Papillomavirus type 16 oncogenes downregulate expression of interferon-responsive genes and upregulate proliferation-associated and NF-kappaB-responsive genes in cervical keratinocytes. J Virol 75:4283–4296
9. Peralta-Zaragoza O, Bermudez-Morales V, Gutierrez-Xicotencatl L et al (2006) E6 and E7 oncoproteins from human papillomavirus type 16 induce activation of human transforming growth factor beta1 promoter throughout Sp1 recognition sequence. Viral Immunol 19:468–480
10. Bermudez-Morales VH, Peralta-Zaragoza O, Alcocer-Gonzalez JM et al (2011) IL-10 expression is regulated by HPV E2 protein in cervical cancer cells. Mol Med Rep 4:369–375
11. Collins S, Rollason TP, Young LS et al (2010) Cigarette smoking is an independent risk factor for cervical intraepithelial neoplasia in young women: a longitudinal study. Eur J Cancer 46:405–411
12. Gadducci A, Barsotti C, Cosio S et al (2011) Smoking habit, immune suppression, oral contraceptive use, and hormone replacement therapy use and cervical carcinogenesis: a review of the literature. Gynecol Endocrinol 27:597–604
13. McCann MF, Irwin DE, Walton LA et al (1992) Nicotine and cotinine in the cervical mucus of smokers, passive smokers, and nonsmokers. Cancer Epidemiol Biomarkers Prev 1:125–129
14. Hellberg D, Nilsson S, Haley NJ et al (1988) Smoking and cervical intraepithelial neoplasia: nicotine and cotinine in serum and cervical mucus in smokers and nonsmokers. Am J Obstet Gynecol 158:910–913
15. Appleby P, Beral V, Berrington de Gonzalez A et al (2006) Carcinoma of the cervix and tobacco smoking: collaborative reanalysis of individual data on 13,541 women with carcinoma of the cervix and 23,017 women without carcinoma of the cervix from 23 epidemiological studies. Int J Cancer 118:1481–1495
16. Castle PE, Wacholder S, Lorincz AT et al (2002) A prospective study of high-grade cervical neoplasia risk among human papillomavirus-infected women. J Natl Cancer Inst 94:1406–1414
17. Katanoda K, Marugame T, Saika K et al (2008) Population attributable fraction of mortality associated with tobacco smoking in Japan: a pooled analysis of three large-scale cohort studies. J Epidemiol 18:251–264
18. Samir R, Asplund A, Tot T et al (2010) Tissue tumor marker expression in smokers, including serum cotinine concentrations, in women with cervical intraepithelial neoplasia or normal squamous cervical epithelium. Am J Obstet Gynecol 202(579):e1–e7
19. Lieberman JA, Moscicki AB, Sumerel JL et al (2008) Determination of cytokine protein levels in cervical mucus samples from young women by a multiplex immunoassay method and assessment of correlates. Clin Vac Immunol 15:49–54
20. Satoh T, Matsumoto K, Fujii T et al (2013) Rapid genotyping of carcinogenic human papillomavirus by loop-mediated isothermal amplification using a new automated DNA test (Clinichip HPV). J Virol Methods 188:83–93
21. Sharma A, Rajappa M, Saxena A et al (2007) Cytokine profile in Indian women with cervical intraepithelial neoplasia and cancer cervix. Int J Gynecol Cancer 17:879–885
22. Kobayashi A, Weinberg V, Darragh T et al (2008) Evolving immunosuppressive microenvironment during human cervical carcinogenesis. Mucosal Immunol 1:412–420
23. Giannini SL, Al-Saleh W, Piron H et al (1998) Cytokine expression in squamous intraepithelial lesions of the uterine cervix: implications for the generation of local immunosuppression. Clin Exp Immunol 113:183–189
24. Iancu IV, Botezatu A, Goia-Rusanu CD et al (2010) TGF-beta signalling pathway factors in HPV-induced cervical lesions. Roum Arch Microbiol Immunol 69:113–118
25. Passmore JA, Milner M, Denny L et al (2006) Comparison of cervical and blood T-cell responses to human papillomavirus-16 in women with human papillomavirus-associated cervical intraepithelial neoplasia. Immunology 119:507–514
26. Sheu BC, Lin RH, Lien HC et al (2001) Predominant Th2/Tc2 polarity of tumor infiltrating lymphocytes in human cervical cancer. J Immunol 167:2972–2978
27. Scott ME, Shvetsov YB, Thompson PJ et al (2013) Cervical cytokines and clearance of incident human papillomavirus infection: Hawaii HPV cohort study. Int J Cancer 133:1187–1196
28. Balkwill F, Mantovani A (2001) Inflammation and cancer: back to Virchow? Lancet 357:539–545
29. Lowe DB, Storkus WJ (2011) Chronic inflammation and immunologic-based constraints in malignant disease. Immunotherapy 3:1265–1274
30. Coussens LM, Werb Z (2002) Inflammation and cancer. Nature 420:860–867
31. Øvestad IT, Gudlaugsson E, Skaland I et al (2010) Local immune response in the microenvironment of CIN2-3 with and without spontaneous regression. Mod Pathol 23:1231–1240
32. Bystry RS, Aluvihare V, Welch KA et al (2001) B cells and professional APCs recruit regulatory T cells via CCL4. Nat Immunol 2:1126–1132
33. 8+ T cells. Science 270:1811–1815
34. Larrubia JR, Benito-Martinez S, Calvino M et al (2008) Role of chemokines and their receptors in viral persistence and liver damage during chronic hepatitis C virus infection. World J Gastroenterol 14:7149–7159
35. Meuronen A, Majuri ML, Alenius H et al (2008) Decreased cytokine and chemokine mRNA expression in bronchoalveolar lavage in asymptomatic smoking subjects. Respiration 75:450–458
36. Koshiol J, Schroeder J, Jamieson DJ et al (2006) Smoking and time to clearance of human papillomavirus infection in HIV-seropositive and HIV-seronegative women. Am J Epidemiol 164:176–183
37. Giuliano AR, Sedjo RL, Roe DJ et al (2002) Clearance of oncogenic human papillomavirus (HPV) infection: effect of smoking (United States). Cancer Causes Control 13:839–846
38. Gritz ER, Dresler C, Sarna L (2005) Smoking, the missing drug interaction in clinical trials: ignoring the obvious. Cancer Epidemiol Biomarkers Prev 14:2287–2293
39. Zeidel A, Beilin B, Yardeni I et al (2002) Immune response in asymptomatic smokers. Acta Anaesthesiol Scand 46:959–964
40. Johnson JD, Houchens DP, Kluwe WM et al (1990) Effects of mainstream and environmental tobacco smoke on the immune system in animals and humans: a review. Crit Rev Toxicol 20:369–395