Treatment of clinical aspiration: A reappraisal

American Journal of Health-System Pharmacy

Volumn 70, Issue 15, 2013, Pages 1291-1300

  Waybright, Ryan A ^a   Coolidge, William ^b   Johnson, Thomas J ^c  

^a Avera McKennan Hospital and University Health Center   (United States)

^b AMHUHC   (United States)

^c Hospital Pharmacy   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTIC AGENT; ANTIINFECTIVE AGENT;

ANTIBIOTIC THERAPY; BACTERIOLOGY; BACTERIUM CULTURE; BACTERIUM ISOLATION; HUMAN; MEDICAL LITERATURE; NONHUMAN; PNEUMONIA; PULMONARY ASPIRATION; REVIEW; ANIMAL; BACTERIA; BACTERIAL INFECTIONS; CLINICAL TRIAL (TOPIC); ISOLATION AND PURIFICATION; PATHOPHYSIOLOGY; PNEUMONIA, ASPIRATION; RISK FACTOR; UNNECESSARY PROCEDURE;

ANIMALS; ANTI-BACTERIAL AGENTS; BACTERIA; BACTERIAL INFECTIONS; CLINICAL TRIALS AS TOPIC; HUMANS; PNEUMONIA, ASPIRATION; RISK FACTORS; UNNECESSARY PROCEDURES;

EID: 84894353089     PISSN: 10792082     EISSN: 15352900     Source Type: Journal    
DOI: 10.2146/ajhp120319     Document Type: Review

References (60)

1. Rebuck JA, Rasmussen JR, Olsen KM. Clinical aspiration-related practice patterns in the intensive care unit: a physician survey. Crit Care Med. 2001; 29: 2239-44.
2. Kane-Gill SL, Olsen KM, Rebuck JA et al. Multicenter treatment and outcome evaluation of aspiration syndromes in critically ill patients. Ann Pharmacother. 2007; 41:549-55.
3. Fauci AS, Braunwald E, Kasper DL et al. Harrison's principles of internal medicine. 17th ed. New York: McGraw-Hill Medical; 2008.
4. Janda M, Scheeren TW, Nöldge-Schomburg GF. Management of pulmonary aspiration. Best Pract Res Clin Anaesthesiol. 2006; 20:409-27.
5. Knight PR, Davidson BA, Russo TA et al. Progressive, severe lung injury secondary to the interaction of insults in gastric aspiration. Exp Lung Res. 2004; 30:535-57.
6. Marik PE. Aspiration pneumonitis and aspiration pneumonia. N Engl J Med. 2001; 344:665-71.
7. Olsson GL, Hallen B, Hambraeus-Jonzon K. Aspiration during anaesthesia: a computer-aided study of 185,358 anaesthetics. Acta Anaesthesiol Scand. 1986; 30:84-92.
8. Warner MA, Waner ME, Weber JG. Clinical significance of pulmonary aspiration during the perioperative period. Anaesthesiology. 1993; 78:56-62.
9. Raghavendran K, Nemzek J, Napolitano LM et al. Aspiration-induced lung injury. Crit Care Med. 2011; 39:818-26.
10. Metheny NA, Clouse RE, Chang YH et al. Tracheobronchial aspiration of gastric contents in critically ill tube-fed patients: frequency, outcomes, and risk factors. Crit Care Med. 2006; 34:1007-15.
11. Finegold SM. Aspiration pneumonia. Rev Infect Dis. 1991; 13(suppl 9):S737-42.
12. Shariatzadeh MR, Huang JQ, Marrie TJ. Differences in the features of aspiration pneumonia according to site of acquisition: community or continuing care facility. J Am Geriatr Soc. 2006; 54:296-302.
13. Kikuchi R, Watabe N, Konno T et al. High incidence of silent aspiration in elderly patients with community-acquired pneumonia. Am J Respir Crit Care Med. 1994; 150:251-3.
14. Leroy O, Vandenbussche C, Coffinier C et al. Community-acquired aspiration pneumonia in intensive care units: epidemiological and prognosis data. Am J Respir Crit Care Med. 1997; 156:1922-9.
15. Huxley EJ, Viroslav J, Gray WR et al. Pharyngeal aspiration in normal adults and patients with depressed consciousness. Am J Med. 1978; 64:564-8.
16. Gleeson K, Eggli DF, Maxwell SL. Quantitative aspiration during sleep in normal subjects. Chest. 1997; 111:1266-72.
17. Bartlett JG, Gorbach SL. The triple threat of aspiration pneumonia. Chest. 1975; 68:560-6.
18. Adnet F, Baud F. Relation between Glasgow Coma Scale and aspiration pneumonia. Lancet. 1996; 348:123-4. Letter.
19. Robbins J, Gensler G, Hind J et al. Comparison of 2 interventions for liquid aspiration on pneumonia incidence: a randomized trial. Ann Intern Med. 2008; 148:509-18.
20. Esparza J, Boivin MA, Hartshorne MF et al. Equal aspiration rates in gastrically and transpylorically fed critically ill patients. Intensive Care Med. 2001; 27: 660-4.
21. Loeb MB, Becker M, Eady A et al. Interventions to prevent aspiration pneumonia in older adults: a systematic review. J Am Geriatr Soc. 2003; 51:1018-22.
22. El-Solh A, Pietrantoni C, Bhat A et al. Microbiology of severe aspiration pneumonia in institutionalized elderly. Am J Respir Crit Care Med. 2003; 167:1650-4.
23. Okuda K, Kimizuka R, Abe S et al. Involvement of periodontopathic anaerobes in aspiration pneumonia. J Periodontol. 2005; 76:2154-60.
24. Mendelson C. The aspiration of stomach contents into the lungs during obstetrical anesthesia. Am J Obstet Gynecol. 1946; 52:191-205.
25. Mitsushima H, Oishi K, Nagao T et al. Acid aspiration induces bacterial pneumonia by enhanced bacterial adherence in mice. Microb Pathog. 2002; 33:203-10.
26. Van Westerloo DJ, Knapp S, van't Veer C et al. Aspiration pneumonitis primes the host for an exaggerated inflammatory response during pneumonia. Crit Care Med. 2005; 33:1770-8.
27. Jaoude PA, Knight PR, Ohtake P et al. Biomarkers in the diagnosis of aspiration syndromes. Expert Rev Mol Diagn. 10:309-19.
28. Adnet F, Borron SW, Vicaut E et al. Value of C-reactive protein in the detection of bacterial contamination at the time of presentation in drug-induced aspiration pneumonia. Chest. 1997; 112:466-71.
29. Mylotte JM, Goodnough S, Naughton BJ et al. Pneumonia versus aspiration pneumonitis in nursing home residents: diagnosis and management. J Am Geriatr Soc. 2003; 51:17-23.
30. Kinsey GC, Murray MJ, Swensen SJ et al. Glucose content of tracheal aspirates: implications for the detection of tube feeding aspiration. Crit Care Med. 1994; 22:1557-62.
31. Yealy DM, Fine MJ. Measurement of serum procalcitonin: a step closer to tailored care for respiratory infections? JAMA. 2009; 302:1115-6.
32. Bouadma L, Luyt CE, Tubach F et al. Use of procalcitonin to reduce patients' exposure to antibiotics in intensive care units (PRORATA trial): a multicentre randomised controlled trial. Lancet. 2010; 375:463-74.
33. Schuetz P, Christ-Crain M, Thomann R et al. Effect of procalcitonin-based guidelines vs standard guidelines on antibiotic use in lower respiratory tract infections: the ProHOSP randomized controlled trial. JAMA. 2009; 302:1059-66.
34. El-Solh AA, Vora H, Knight PR et al. Diagnostic use of serum procalcitonin levels in pulmonary aspiration syndromes. Crit Care Med. 2011; 39:1251-6.
35. Bartlett JG. Anaerobic bacterial infections of the lung and pleural space. Clin Infect Dis. 1993; 16(suppl 4):S248-55.
36. Theerthakarai R, El-Halees W, Ismail M et al. Nonvalue of the initial microbiological studies in the management of non-severe community-acquired pneumonia. Chest. 2001; 119:181-4.
37. Lorber B, Swenson RM. Bacteriology of aspiration pneumonia: a prospective study of community- and hospital-acquired cases. Ann Intern Med. 1974; 81:329-31.
38. Bartlett JG, Gorbach SL. Treatment of aspiration pneumonia and primary lung abscess. Penicillin G vs clindamycin. JAMA. 1975; 234:935-7.
39. Mier L, Dreyfuss D, Darchy B et al. Is penicillin G an adequate initial treatment for aspiration pneumonia? A prospective evaluation using a protected specimen brush and quantitative cultures. Intensive Care Med. 1993; 19:279-84.
40. Marik PE, Careau P. The role of anaerobes in patients with ventilator-associated pneumonia and aspiration pneumonia: a prospective study. Chest. 1999; 115:178-83.
41. Kadowaki M, Demura Y, Mizuno S et al. Reappraisal of clindamycin IV monotherapy for treatment of mild-to-moderate aspiration pneumonia in elderly patients. Chest. 2005; 127:1276-82.
42. Ott SR, Allewelt M, Lorenz J et al. Moxifloxacin vs ampicillin/sulbactam in aspiration pneumonia and primary lung abscess. Infection. 2008; 36:23-30.
43. Tokuyasu H, Harada T, Watanabe E et al. Effectiveness of meropenem for the treatment of aspiration pneumonia in elderly patients. Intern Med. 2009; 48:129-35.
44. Ito I, Kadowaki S, Tanabe N et al. Tazobactam/piperacillin for moderate-to-severe pneumonia in patients with risk for aspiration: comparison with imipenem/cilastatin. Pulm Pharmacol Ther. 2010; 23:403-10.
45. Talaie H, Jabari HR, Shadnia S et al. Cefepime/clindamycin vs. ceftriaxone/clindamycin for the empiric treatment of poisoned patients with aspiration pneumonia. Acta Biomed. 2008; 79:117-22.
46. Gonzalez-C CL, Calia FM. Bacteriologic flora of aspiration-induced pulmonary infections. Arch Intern Med. 1975; 135:711-4.
47. Smith DT. Fuso-spirochaetal diseases of the lungs. Tubercle. 1928; 9:420-37.
48. Smith DT. Experimental aspiratory abscess. Arch Surg. 1927; 14:231-9.
49. Moser KM, Maurer J, Jassy L et al. Sensitivity, specificity, and risk of diagnostic procedures in a canine model of Streptococcus pneumoniae pneumonia. Am Rev Respir Dis. 1982; 125:436-42.
50. Irwin RS, Demers RR, Prater MR et al. Evaluation of methylene blue and squamous epithelial cells as oropharyngeal markers: a means of identifying oropharyngeal contamination during transtracheal aspiration. J Infect Dis. 1980; 141:165-71.
51. Mandell LA, Wunderink RG, Anzueto A et al. Infectious Diseases Society of America/American Thoracic Society consensus guidelines on the management of community acquired pneumonia in adults. Clin Infect Dis. 2007; 44(suppl 2):S27-72.
52. American Thoracic Society, Infectious Diseases Society of America. Guidelines for the management of adults with hospital-acquired, ventilator-associated, and healthcare-associated pneumonia. Am J Respir Crit Care Med. 2005; 171:388-416.
53. Gilbert DN, Moellering RC Jr, Eliopoulos GM et al. The Sanford guide to antimicrobial therapy, 41st ed. Sperryville, VA: Antimicrobial Therapy; 2011.
54. Wang JL, Chen KY, Fang CT et al. Changing bacteriology of adult community-acquired lung abscess in Taiwan: Klebsiella pneumoniae versus anaerobes. Clin Infect Dis. 2005; 40:915-22.
55. Bartlett JG. The role of anaerobic bacteria in lung abscess. Clin Infect Dis. 2005; 40:923-5.
56. Polenakovik H, Burdette SD, Polenakovik S. Moxifloxacin is efficacious for treatment of community-acquired lung abscesses in adults. Clin Infect Dis. 2005; 41:764-5.
57. Wolfe JE, Bone RC, Ruth WE et al. Effects of corticosteroids in the treatment of patients with gastric aspiration. Am J Med. 1977; 63:719-22.
58. Sukumaran M, Granada MJ, Berger HW et al. Evaluation of corticosteroid treatment in aspiration of gastric contents: a controlled clinical trial. Mt Sinai J Med. 1980; 47:335-40.
59. Centers for Disease Control and Prevention. Get smart: know when antibiotics work. www.cdc.gov/getsmart/campaign-materials/online-materials.html (accessed 2012 Jan 15).
60. Infectious Diseases Society of America. Antibiotic development: the 10 x '20 Initiative. www.idsociety.org/10x20 (accessed 2012 Jan 15).