Effectiveness of meropenem for the treatment of aspiration pneumonia in elderly patients

Internal Medicine

Volumn 48, Issue 3, 2009, Pages 129-135

  Tokuyasu, Hirokazu ^a   Harada, Tomoya ^a   Watanabe, Etsuko ^a   Okazaki, Ryouta ^a   Touge, Hirokazu ^a   Kawasaki, Yuji ^a   Shimizu, Eiji ^b  

^a MATSUE RED CROSS HOSPITAL   (Japan)

^b TOTTORI UNIVERSITY   (Japan)

Author keywords

Anaerobic bacteria; Aspiration pneumonia; Elderly; Fiberoptic bronchoscopy; Meropenem

Indexed keywords

MEROPENEM;

AEROBIC BACTERIUM; AGED; ALKALINE PHOSPHATASE BLOOD LEVEL; ANAEROBIC BACTERIUM; ARTICLE; ASPIRATION PNEUMONIA; BACTERIUM DETECTION; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DIARRHEA; DISEASE SEVERITY; DRUG EFFICACY; DRUG SAFETY; DRUG TOLERABILITY; ELDERLY CARE; ENTEROBACTERIACEAE; EOSINOPHILIA; FEMALE; FIBEROPTIC BRONCHOSCOPY; GRAM NEGATIVE BACTERIUM; HUMAN; JAPAN; LIVER DYSFUNCTION; MAJOR CLINICAL STUDY; MALE; MORTALITY; PRACTICE GUIDELINE; SIDE EFFECT;

AGED; AGED, 80 AND OVER; ANTI-BACTERIAL AGENTS; BACTERIA, AEROBIC; BACTERIA, ANAEROBIC; FEMALE; HUMANS; MALE; PNEUMONIA, ASPIRATION; PNEUMONIA, BACTERIAL; PROSPECTIVE STUDIES; SPUTUM; THIENAMYCINS;

EID: 61749090546     PISSN: 09182918     EISSN: 13497235     Source Type: Journal    
DOI: 10.2169/internalmedicine.48.1308     Document Type: Article

References (29)

1. Janssens JP, Krause KH. Pneumonia in the very old. Lancet Infect Dis 4: 112-124, 2004.
2. Horner J, Massey EW, Riski JE, Lathrop DL, Chase KN. Aspiration following stroke: clinical correlates and outcome. Neurology 38: 1359-1362, 1982.
3. Chouinard J. Dysphagia in Altzheimer disease: a review. J Nutr Aging 4: 214-217, 2000.
4. Johanson WG, Pierce AK, Sanford JP, Thomas GD. Nosocominal respiratory infections with gram-negative bacilli: the significance of colonization of the respiratory tract. Ann Intern Med 77: 701-706, 1972.
5. Bartlett JG, Gorbach SL, Finegold SM. The bacteriology of aspiration pneumonia. Am J Med 56: 202-207, 1974.
6. Lowe MN, Lamb HM. Meropenem: an update review of its use in the management of intra-abdominal infections. Drugs 60: 619-646, 2000.
7. The Committee of the Japanese Respiratory Society. Guidelines for management of hospital-acquired pneumonia: the basic concept of management for hospital-acquired pneumonia in adults. Kyorinsya, Tokyo, Japan, 2002: 27-34 (in Japanese).
8. American Thoracic Society. Hospital-acquired pneumonia in adults: diagnosis, assessment of severity, initial antimicrobial therapy, and preventative strategies. Am J Respir Crit Care Med 153: 1711-1725, 1995.
9. The Infectious Diseases of America. Practice guidelines of the management of community-acquired pneumonia in adults. Clin Infect Dis 31: 347-382, 2000.
10. Fine MJ, Auble TE, Yealy DM, et al. A prediction rule to identify low-risk patients with community-acquired pneumonia. N Engl J Med 336: 243-250, 1997.
11. El Solh AA, Akinnusi ME, Pineda LA, Mankowski CR. Diagnostic yield of quantitative endotracheal aspirates in patients with severe nursing home-acquired pneumonia. Crit Care 11: R57, 2007.
12. Saito A, Miki F, Oizumi K, et al. Clinical evaluation methods for new antimicrobial agents to treat respiratory infections: report of the Committee for the Respiratory System, Japan Society of Chemotherapy. J Infect Chemother 5: 110-123, 1999.
13. Bartlett J, Gorbach SL, Finegold SM. The bacteriology of aspiration pneumonia. Am J Med 56: 202-207, 1974.
14. Lode H. Microbiological and clinical aspects of aspiration pneumonia. J Antimicrob Chemother 21: 83-90, 1988.
15. El-Solh AA, Pietrantoni C, Bhat A, et al. Microbiology of severe aspiration pneumonia in institutionalized elderly. Am J Respir Crit Care Med 167: 1650-1654, 2003.
16. Bartlett JG. Anaerobic bacterial infections of the lung and pleural space. Clin Infect Dis 16: S248-S255, 1993.
17. Shinzato T, Saito A. The Streptococcus milleri group as a cause of pulmonary infections. Clin Infect Dis 21: S238-S243, 1995.
18. Finegold SM. Respiratory tract and other thoracic infection. In: Anaerobic Bacteria in Human Disease. Finegold SM, Ed. Academic Press, New York, 1977: 223-256.
19. Farley MM. Group B streptococcal infection in older patients. Spectrum of disease and management strategies. Drugs Aging 6: 293-300, 1995.
20. Hoffmann S. The throat carrier rate of group A and other beta hemolytic streptococci among patients in general practice. Acta Pathol Microbiol Immunol Scand [B] 93: 347-351, 1985.
21. Verghese A, Berk SL, Boelen LJ, Smith JK. Group B Streptococcal pneumonia in the elderly. Arch Intern Med 142: 1642-1645, 1982.
22. Trivalle C, Martin E, Martel P, Jacque B, Menard JF, Lemeland JF. Group B streptococcal bacteraemia in the elderly. J Med Microbiol 47: 649-652, 1998.
23. Higuchi JH, Coalson JJ, Johanson WG Jr. Bacteriologic diagnosis of nosocomial pneumonia in primates. Usefulness of the protected specimen brush. Am Rev Respir Dis 125: 53-57, 1982.
24. Kalinske RW, Parker RH, Brandt D, Hoeprich PD. Diagnostic usefulness and safety of transtracheal aspiration. N Engl J Med 276: 604-608, 1976.
25. Kirkpatrick MB, Bass JB. Quantitative bacterial cultures of bronchoalveolar lavage fluids and protected brush catheter specimens from normal subjects. Am Rev Respir Dis 139: 546-548, 1989.
26. Wimberly NW, Bass JB, Boyd BW, et al. Use of a bronchoscopic protected catheter brush for the diagnosis of pulmonary infections. Chest 81: 556-562, 1982.
27. Pollock HM, Hawkins EL, Bonner JR, et al. Diagnosis of bacterial pulmonary infections quantitative protected catheter cultures obtained during bronchoscopy. J Clin Microbiol 17: 255-259, 1983.
28. Baselski VS, El-Torky M, Coalson J, Griffin JP. The standardization of criteria for processing and interpreting laboratory specimens inpatients with suspected ventilator-associated pneumonia. Chest 102 (suppl): S571-S579, 1992.
29. Kadowaki M, Demura Y, Mizuno S, et al. Reappraisal of clindamycin IV monotherapy for treatment of mild-to-modearate aspiration pneumonia in elderly patients. Chest 127: 1276-1282, 2005.