Monocyte subset accumulation in the human heart following acute myocardial infarction and the role of the spleen as monocyte reservoir

European Heart Journal

Volumn 35, Issue 6, 2014, Pages 376-385

  Van Der Laan, Anja M ^a   Ter Horst, Ellis N ^a,b,c   Delewi, Ronak ^a   Begieneman, Mark P V ^b   Krijnen, Paul A J ^b   Hirsch, Alexander ^a   Lavaei, Mehrdad ^b   Nahrendorf, Matthias ^d   Horrevoets, Anton J ^b   Niessen, Hans W M ^b   Piek, Jan J ^a  

^a UNIVERSITY OF AMSTERDAM   (Netherlands)

^b VU UNIVERSITY MEDICAL CENTER   (Netherlands)

^c ROYAL NETHERLANDS ACADEMY OF ARTS AND SCIENCES   (Netherlands)

^d MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

Acute myocardial infarction; Bone marrow; Inflammation; Monocytes; Spleen

Indexed keywords

ACUTE MYOCARDIAL INFARCTION; BONE MARROW; INFLAMMATION; MONOCYTES; SPLEEN;

AGED; ANTIGENS, CD; BONE MARROW CELLS; CASE-CONTROL STUDIES; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; MONOCYTES; MYOCARDIAL INFARCTION; MYOCARDIUM; SPLEEN;

EID: 84894288342     PISSN: 0195668X     EISSN: 15229645     Source Type: Journal    
DOI: 10.1093/eurheartj/eht331     Document Type: Article

References (29)

1. Ertl G, Frantz S. Healing after myocardial infarction. Cardiovasc Res 2005;66:22-32.
2. Frantz S, Bauersachs J, Ertl G. Post-infarct remodelling: contribution of wound healing and inflammation. Cardiovasc Res 2009;81:474-481.
3. Frangogiannis NG. The mechanistic basis of infarct healing. Antioxid Redox Signal 2006;8:1907-1939.
4. Frangogiannis NG. The immune system and cardiac repair. Pharmacol Res 2008;58: 88-111.
5. Lambert JM, Lopez EF, Lindsey ML. Macrophage roles following myocardial infarction. Int J Cardiol 2008;130:147-158.
6. Nahrendorf M, Pittet MJ, Swirski FK. Monocytes: protagonists of infarct inflammation and repair after myocardial infarction. Circulation 2010;121:2437-2445.
7. van der Laan AM, Hirsch A, Robbers LF, Nijveldt R, Lommerse I, Delewi R, van der Vleuten PA, Biemond BJ, Zwaginga JJ, van der Giessen WJ, Zijlstra F, van RossumAC, Voermans C, van der Schoot CE, Piek JJ. A proinflammatory monocyte response is associated with myocardial injury and impaired functional outcome in patients with ST-segment elevation myocardial infarction monocytes and myocardial infarction. Am Heart J 2012;163:57-65.
8. Ziegler-Heitbrock L, Ancuta P, Crowe S, Dalod M, Grau V, Hart DN, Leenen PJ, Liu YJ, MacPherson G, Randolph GJ, Scherberich J, Schmitz J, Shortman K, Sozzani S, Strobl H, Zembala M, Austyn JM, Lutz MB. Nomenclature of monocytes and dendritic cells in blood. Blood 2010;116:e74-e80.
9. Leuschner F, Rauch PJ, Ueno T, Gorbatov R, Marinelli B, LeeWW, Dutta P,Wei Y, Robbins C, Iwamoto Y, Sena B, Chudnovskiy A, Panizzi P, Keliher E, Higgins JM, Libby P, Moskowitz MA, Pittet MJ, Swirski FK,Weissleder R, Nahrendorf M. Rapid monocyte kinetics in acute myocardial infarction are sustained by extramedullary monocytopoiesis. J Exp Med 2012;209:123-137.
10. Swirski FK, Nahrendorf M, Etzrodt M, Wildgruber M, Cortez-Retamozo V, Panizzi P, Figueiredo JL, Kohler RH, Chudnovskiy A, Waterman P, Aikawa E, Mempel TR, Libby P,Weissleder R, Pittet MJ. Identification of splenic reservoir monocytes and their deployment to inflammatory sites. Science 2009;325:612-616.
11. Maekawa Y, Anzai T, Yoshikawa T, Asakura Y, Takahashi T, Ishikawa S, Mitamura H, Ogawa S. Prognostic significance of peripheral monocytosis after reperfused acute myocardial infarction: a possible role for left ventricular remodeling. J AmColl Cardiol 2002;39:241-246.
12. Mariani M, Fetiveau R, Rossetti E, Poli A, Poletti F, Vandoni P, D'Urbano M, Cafiero F, Mariani G, Klersy C, De SS. Significance of total and differential leucocyte count in patients with acute myocardial infarction treated with primary coronary angioplasty. Eur Heart J 2006;27:2511-2515.
13. Tsujioka H, Imanishi T, Ikejima H, Kuroi A, Takarada S, Tanimoto T, Kitabata H, Okochi K, Arita Y, Ishibashi K, Komukai K, Kataiwa H, Nakamura N, Hirata K, Tanaka A, Akasaka T. Impact of heterogeneity of human peripheral blood monocyte subsets on myocardial salvage in patients with primary acute myocardial infarction. J Am Coll Cardiol 2009;54:130-138.
14. Geissmann F, Manz MG, Jung S, Sieweke MH, Merad M, Ley K. Development of monocytes, macrophages, and dendritic cells. Science 2010;327:656-661.
15. Nahrendorf M, Swirski FK, Aikawa E, Stangenberg L, Wurdinger T, Figueiredo JL, Libby P, Weissleder R, Pittet MJ. The healing myocardium sequentially mobilizes two monocyte subsets with divergent and complementary functions. J Exp Med 2007;204:3037-3047.
16. Chow LH, Ye Y, Linder J, McManus BM. Phenotypic analysis of infiltrating cells in human myocarditis. An immunohistochemical study in paraffin-embedded tissue. Arch Pathol Lab Med 1989;113:1357-1362.
17. Cortez-Retamozo V, Etzrodt M, Newton A, Rauch PJ, Chudnovskiy A, Berger C, Ryan RJ, Iwamoto Y, Marinelli B, Gorbatov R, Forghani R, Novobrantseva TI, Koteliansky V, Figueiredo JL, Chen JW, Anderson DG, Nahrendorf M, Swirski FK, Weissleder R, Pittet MJ. Origins of tumor-associated macrophages and neutrophils. Proc Natl Acad Sci USA 2012;109:2491-2496.
18. Delano MJ, Thayer T, Gabrilovich S, Kelly-Scumpia KM, Winfield RD, Scumpia PO, Cuenca AG, Warner E, Wallet SM, Wallet MA, O'Malley KA, Ramphal R, Clare-Salzer M, Efron PA, Mathews CE, Moldawer LL. Sepsis induces early alterations in innate immunity that impact mortality to secondary infection. J Immunol 2011;186:195-202.
19. Orde MM, Puranik R, Morrow PL, Duflou J. Myocardial pathology in pulmonary thromboembolism. Heart 2011;97:1695-1699.
20. Fishbein MC, Maclean D, Maroko PR. The histopathologic evolution of myocardial infarction. Chest 1978;73:843-849.
21. Krijnen PA, Ciurana C, Cramer T, Hazes T, Meijer CJ, Visser CA, Niessen HW, Hack CE. Igm colocalises with complement and C reactive protein in infarcted human myocardium. J Clin Pathol 2005;58:382-388.
22. White PD, Mallory GK, Salcedo-Salgar J. The speed of healing of myocardial infarcts. Trans Am Clin Climatol Assoc 1936;52:97-104.
23. Hadi AM, Mouchaers KT, Schalij I, GrunbergK, Meijer GA, Vonk-Noordegraaf A, van der Laarse WJ, Belien JA. Rapid quantification of myocardial fibrosis: a new macrobased automated analysis. Anal Cell Pathol 2010;33:257-269.
24. Vermeulen EG, Niessen HW, Bogels M, Stehouwer CD, Rauwerda JA, van Hinsbergh VW. Decreased smooth muscle cell/extracellular matrix ratio of media of femoral artery in patients with atherosclerosis and hyperhomocysteinemia. Arterioscler Thromb Vasc Biol 2001;21:573-577.
25. Krijnen PA, Meischl C, Nijmeijer R, Visser CA, Hack CE, NiessenHW. Inhibition of sPLA2-IIA, C-reactive protein or complement: new therapy for patients with acute myocardial infarction? Cardiovasc Hematol Disord Drug Targets 2006;6:113-123.
26. Zawada AM, Rogacev KS, Rotter B, Winter P, Marell RR, Fliser D, Heine GH. Super-SAGE evidence for CD14++CD16+ monocytes as a third monocyte subset. Blood 2011;118:e50-e61.
27. Geissmann F, Jung S, Littman DR. Blood monocytes consist of two principal subsets with distinct migratory properties. Immunity 2003;19:71-82.
28. Haeusler KG, SchmidtWU,Foehring F, Meisel C,Guenther C, BruneckerP, Kunze C, Helms T, Dirnagl U, Volk HD, Villringer A. Immune responses after acute ischemic stroke or myocardial infarction. Int J Cardiol 2012;155:372-377.
29. Dutta P, Courties G, Wei Y, Leuschner F, Gorbatov R, Robbins CS, Iwamoto Y, Thompson B, Carlson AL, Heidt T, Majmudar MD, Lasitschka F, Etzrodt M, Waterman P, Waring MT, Chicoine AT, van der Laan AM, Niessen HW, Piek JJ, Rubin BB, Butany J, Stone JR, Katus HA, Murphy SA, Morrow DA, Sabatine MS, Vinegoni C, Moskowitz MA, Pittet MJ, Libby P, Lin CP, Swirski FK, Weissleder R, Nahrendorf M. Myocardial infarction accelerates atherosclerosis. Nature 2012; 487:325-329.