Growth factors engineered for super-affinity to the extracellular matrix enhance tissue healing

Science

Volumn 343, Issue 6173, 2014, Pages 885-888

  Martino, Mikaël M ^a,b   Briquez, Priscilla S ^a   Güç, Esra ^a   Tortelli, Federico ^a   Kilarski, Witold W ^a   Metzger, Stephanie ^a   Rice, Jeffrey J ^a,c   Kuhn, Gisela A ^d   Mul̈ler, Ralph ^d   Swartz, Melody A ^a   Hubbell, Jeffrey A ^a  

^a EPFL   (Switzerland)

^b OSAKA UNIVERSITY   (Japan)

^c Tennessee Technological University   (United States)

^d ETH ZURICH   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

ALKALINE PHOSPHATASE; BONE MORPHOGENETIC PROTEIN 2; COLLAGEN TYPE 1; FIBRINOGEN; FIBRONECTIN; GROWTH FACTOR; NEUROPILIN 1; OSTEOPONTIN; PLACENTA GROWTH FACTOR 2; PLACENTAL GROWTH FACTOR; PLATELET DERIVED GROWTH FACTOR BB; TENASCIN; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG; VASCULOTROPIN A; VASCULOTROPIN RECEPTOR 2; VITRONECTIN;

BONE; CHEMICAL BINDING; COMPARATIVE STUDY; CYTOLOGY; GROWTH REGULATOR; MEDICINE; SIGNAL;

ANGIOGENESIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BINDING AFFINITY; BIOENGINEERING; BLOOD VESSEL PERMEABILITY; BONE DEFECT; BONE REGENERATION; BONE REMODELING; CHRONIC WOUND; CONTROLLED STUDY; EXTRACELLULAR MATRIX; GRANULOCYTE; IN VIVO STUDY; MESENCHYMAL STEM CELL; MICRO-COMPUTED TOMOGRAPHY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN PHOSPHORYLATION; SMOOTH MUSCLE FIBER; TISSUE REGENERATION; TISSUE REPAIR; WOUND HEALING; WOUND HEALING IMPAIRMENT;

EID: 84894256030     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.1247663     Document Type: Article

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