Vitamin D status and community-acquired pneumonia: Results from the third national health and nutrition examination survey

PLoS ONE

Volumn 8, Issue 11, 2013, Pages

  Quraishi, Sadeq A ^a,b   Bittner, Edward A ^a,b   Christopher, Kenneth B ^a,c   Camargo Jr , Carlos A ^a,b,d  

^a HARVARD MEDICAL SCHOOL   (United States)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

^c BRIGHAM AND WOMEN S HOSPITAL   (United States)

^d HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

25-HYDROXYVITAMIN D; VITAMIN D;

ADULT; AGE; AGED; ANALOGS AND DERIVATIVES; ASTHMA; BLOOD; CARDIOVASCULAR DISEASES; COMMUNITY-ACQUIRED INFECTIONS; COMPLICATION; DIABETES MELLITUS; DRINKING BEHAVIOR; FEMALE; HUMAN; MALE; MIDDLE AGED; NUTRITION; PNEUMONIA, BACTERIAL; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE; RENAL INSUFFICIENCY, CHRONIC; SEX DIFFERENCE; SOCIAL CLASS; STATISTICAL MODEL; STATISTICS AND NUMERICAL DATA; UNITED STATES; VITAMIN D DEFICIENCY;

ADULT; AGE FACTORS; AGED; ALCOHOL DRINKING; ASTHMA; CARDIOVASCULAR DISEASES; COMMUNITY-ACQUIRED INFECTIONS; DIABETES MELLITUS; FEMALE; HUMANS; LOGISTIC MODELS; MALE; MIDDLE AGED; NUTRITION SURVEYS; PNEUMONIA, BACTERIAL; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE; RENAL INSUFFICIENCY, CHRONIC; SEX FACTORS; SOCIAL CLASS; UNITED STATES; VITAMIN D; VITAMIN D DEFICIENCY;

EID: 84894099420     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0081120     Document Type: Article

References (50)

1. Mandell LA, Wunderink RG, Anzueto A, Bartlett JG, Campbell GD et al. (2007) Infectious Diseases Society of America/American Thoracic Society consensus guidelines on the management of communityacquired pneumonia in adults. Clin Infect Dis 44 Suppl 2: S27-S72. doi:10.1086/511159. PubMed: 17278083. (Pubitemid 46290553)
2. Niederman M (2009) In the clinic. Community-acquired pneumonia. Ann Intern Med 151:ITC4-14
3. File TM Jr, Marrie TJ (2010) Burden of community-acquired pneumonia in North American adults. Postgrad Med 122: 130-141. doi:10.3810/pgm.2010.03.2130. PubMed: 20203464.
4. Watkins RR, Lemonovich TL (2011) Diagnosis and management of community-acquired pneumonia in adults. Am Fam Physician 83: 1299-1306. PubMed: 21661712.
5. Feikin DR, Schuchat A, Kolczak M, Barrett NL, Harrison LH et al. (2000) Mortality from invasive pneumococcal pneumonia in the era of antibiotic resistance,1995-1997. Am J Public Health 90: 223-229. doi:10.2105/AJPH.90.2.223. PubMed: 10667183. (Pubitemid 30062674)
6. Centers for Disease Control and Prevention Fast Stats. Deaths and mortality. Available: http://www.cdc.gov/nchs/fastats/pneumonia.htm. Accessed 8 May. p. 8 (2013).
7. Ramirez JA, Anzueto AR (2011) Changing needs of community-acquired pneumonia. J Antimicrob Chemother 66: S3-S9. doi:10.1093/jac/dkr119. PubMed: 21482567.
8. Wunderink RG, Waterer GW (2004) Community-acquired pneumonia: pathophysiology and host factors with focus on possible new approaches to management of lower respiratory tract infections. Infect Dis Clin North Am 18: 743-759. doi:10.1016/j.idc.2004.07.004. PubMed: 15555822. (Pubitemid 39536006)
9. Leow L, Simpson T, Cursons R, Karalus N, Hancox RJ (2011) Vitamin D, innate immunity and outcomes in community acquired pneumonia. Respirology 16: 611-616. doi:10.1111/j.1440-1843.2011.01924.x. PubMed: 21244571.
10. Remmelts HH, van de Garde EM, Meijvis SC, Peelen EL, Damoiseaux JG et al. (2012) Addition of vitamin D status to prognostic scores improves the prediction of outcome in community-acquired pneumonia. Clin Infect Dis 55: 1488-1494. doi:10.1093/cid/cis751. PubMed: 22942205.
11. Aregbesola A, Voutilainen S, Nurmi T, Virtanen JK, Ronkainen K et al. (2013) Serum 25-hydroxyvitamin D3 and the risk of pneumonia in an ageing general population. J Epidemiol Community Health 67: 533-536. doi:10.1136/jech-2012- 202027. PubMed: 23596250.
12. Hughes DA, Norton R (2009) Vitamin D and respiratory health. Clin Exp Immunol 158: 20-25. doi:10.1111/j.1365-2249.2009.04001.x. PubMed: 19737226.
13. Herr C, Greulich T, Koczulla RA, Meyer S, Zakharkina T et al. (2011) The role of vitamin D in pulmonary disease: COPD, asthma, infection, and cancer. Respir Res 12: 31. doi:10.1186/1465-9921-12-31. PubMed: 21418564.
14. Finklea JD, Grossmann RE, Tangpricha V (2011) Vitamin D and chronic lung disease: a review of molecular mechanisms and clinical studies. Adv Nutr 2: 244-253. doi:10.3945/an.111.000398. PubMed: 22332056.
15. Holick MF, Binkley NC, Bischoff-Ferrari HA, Gordon CM, Hanley DA et al. (2011) Evaluation, treatment, and prevention of vitamin D deficiency: an Endocrine Society clinical practice guideline. J Clin Endocrinol Metab 96: 1911-1930. doi:10.1210/jc.2011-0385. PubMed: 21646368.
16. Cleveland WS (1979) Robust locally weighted regression and smoothing scatterplots. J Am Stat Assoc 74: 829-836. doi:10.1080/01621459.1979.10481038.
17. Cleveland WS, Devlin SJ (1988) Locally weighted regression: an approach to regression analysis by local fitting. J Am Stat Assoc 83: 596-610. doi:10.1080/01621459.1988.10478639.
18. Adams JS, Hewison M (2008) Unexpected actions of vitamin D: new perspectives on the regulation of innate and adaptive immunity. Nat Clin Pract Endocrinol Metab 4: 80-90. doi:10.1038/ncpendmet0716. PubMed: 18212810. (Pubitemid 351156900)
19. Fabri M, Stenger S, Shin DM, Yuk JM, Liu PT et al. (2011) Vitamin D is required for IFN-gamma-mediated antimicrobial activity of human macrophages. Sci Transl Med 3:104ra102. PubMed: 21998409.
20. Kankova M, Luini W, Pedrazzoni M, Riganti F, Sironi M et al. (1991) Impairment of cytokine production in mice fed a vitamin D3-deficient diet. Immunology 73: 466-471. PubMed: 1655638.
21. Liu PT, Stenger S, Tang DH, Modlin RL (2007) Cutting edge: vitamin D-mediated human antimicrobial activity against Mycobacterium tuberculosis is dependent on the induction of cathelicidin. J Immunol 179: 2060-2063. PubMed: 17675463.
22. Liu PT, Stenger S, Li H, Wenzel L, Tan BH et al. (2006) Toll-like receptor triggering of a vitamin D-mediated human antimicrobial response. Science 311: 1770-1773. doi:10.1126/science.1123933. PubMed: 16497887.
23. Holick MF (2007) Vitamin D deficiency. N Engl J Med 357: 266-281. doi:10.1056/NEJMra070553. PubMed: 17634462.
24. Bhalla AK, Amento EP, Krane SM (1986) Differential effects of 1,25-dihydroxyvitamin D3 on human lymphocytes and monocyte/macrophages: inhibition of interleukin-2 and augmentation of interleukin-1 production. Cell Immunol 98: 311-322. doi:10.1016/0008-8749(86)90291-1. PubMed: 3489547. (Pubitemid 16112035)
25. Pinheiro da Silva F, Machado MC (2012) Antimicrobial peptides: clinical relevance and therapeutic implications. Peptides 36: 308-314. doi:10.1016/j.peptides.2012.05.014. PubMed: 22659161.
26. Dürr UH, Sudheendra US, Ramamoorthy A (2006) LL-37, the only human member of the cathelicidin family of antimicrobial peptides. Biochim Biophys Acta 1758: 1408-1425. doi:10.1016/j.bbamem.2006.03.030. PubMed: 16716248. (Pubitemid 44436081)
27. Tollin M, Bergman P, Svenberg T, Jörnvall H, Gudmundsson GH et al. (2003) Antimicrobial peptides in the first line defence of human colon mucosa. Peptides 24: 523-530. doi:10.1016/S0196-9781(03)00114-1. PubMed: 12860195. (Pubitemid 36829340)
28. Ginde AA, Mansbach JM, Camargo CA Jr. (2009) Association between serum 25-hydroxyvitamin D level and upper respiratory tract infection in the Third National Health and Nutrition Examination Survey. Arch Intern Med 169: 384-390. doi:10.1001/archinternmed.2008.560. PubMed: 19237723.
29. Berry DJ, Hesketh K, Power C, Hyppönen E (2011) Vitamin D status has a linear association with seasonal infections and lung function in British adults. Br J Nutr 106: 1433-1440. doi:10.1017/S0007114511001991. PubMed: 21736791.
30. McNally JD, Leis K, Matheson LA, Karuananyake C, Sankaran K et al. (2009) Vitamin D deficiency in young children with severe acute lower respiratory infection. Pediatr Pulmonol 44: 981-988. doi:10.1002/ppul.21089. PubMed: 19746437.
31. Belderbos ME, Houben ML, Wilbrink B, Lentjes E, Bloemen EM et al. (2011) Cord blood vitamin D deficiency is associated with respiratory syncytial virus bronchiolitis. Pediatrics 127: e1513-1520. PubMed: 21555499.
32. Mulligan JK, Bleier BS, O'Connell B, Mulligan RM, Wagner C et al. (2011) Vitamin D3 correlates inversely with systemic dendritic cell numbers and bone erosion in chronic rhinosinusitis with nasal polyps and allergic fungal rhinosinusitis. Clin Exp Immunol 164: 312-320. doi:10.1111/j.1365-2249.2011. 04325.x. PubMed: 21401575.
33. Mulligan JK, White DR, Wang EW, Sansoni SR, Moses H et al. (2012) Vitamin D3 deficiency increases sinus mucosa dendritic cells in pediatric chronic rhinosinusitis with nasal polyps. Otolaryngol Head Neck Surg 147: 773-781. doi:10.1177/0194599812448852. PubMed: 22627120.
34. Quraishi SA, Bittner EA, Blum L, Hutter MM, Camargo CA Jr. (In press) Preoperative 25-hydroxyvitamin D level is associated with risk of hospital-acquired infections following Roux-en-Y gastric bypass surgery. JAMA. Surgery.
35. Quraishi SA, Litonjua AA, Moromizato T, Gibbons FK, Camargo CA Jr et al. (2013) Association between pre-hospital vitamin D deficiency and hospital-acquired bloodstream infections. Am J Clin Nutr 98: 952-959. doi:10.3945/ajcn.113.058909. PubMed: 23945717.
36. Bergman P, Lindh AU, Björkhem-Bergman L, Lindh JD (2013) Vitamin D and respiratory tract infections: A systematic review and metaanalysis of randomized controlled trials. PLOS ONE 8: e65835. doi:10.1371/journal.pone. 0065835. PubMed: 23840373.
37. Mao S, Huang S (2013) Vitamin D supplementation and risk of respiratory tract infections: A meta-analysis of randomized controlled trials. Scand J Infect Dis 45: 696-702. doi:10.3109/00365548.2013.803293. PubMed: 23815596.
38. Laaksi I, Ruohola JP, Mattila V, Auvinen A, Ylikomi T et al. (2010) Vitamin D supplementation for the prevention of acute respiratory tract infection: a randomized, double-blinded trial among young Finnish men. J Infect Dis 202: 809-814. doi:10.1086/654881. PubMed: 20632889.
39. Murdoch DR, Slow S, Chambers ST, Jennings LC, Stewart AW et al. (2012) Effect of vitamin D3 supplementation on upper respiratory tract infections in healthy adults: the VIDARIS randomized controlled trial. JAMA 308: 1333-1339. doi:10.1001/jama.2012.12505. PubMed: 23032549.
40. Li-Ng M, Aloia JF, Pollack S, Cunha BA, Mikhail M et al. (2009) A randomized controlled trial of vitamin D3 supplementation for the prevention of symptomatic upper respiratory tract infections. Epidemiol Infect 137: 1396-1404. doi:10.1017/S0950268809002404. PubMed: 19296870.
41. Camargo CA Jr, Ganmaa D, Frazier AL, Kirchberg FF, Stuart JJ et al. (2012) Randomized trial of vitamin D supplementation and risk of acute respiratory infection in Mongolia. Pediatrics 130: e561-e567. doi:10.1542/peds.2011-3029. PubMed: 22908115.
42. Manaseki-Holland S, Maroof Z, Bruce J, Mughal MZ, Masher MI et al. (2012) Effect on the incidence of pneumonia of vitamin D supplementation by quarterly bolus dose to infants in Kabul: a randomised controlled superiority trial. Lancet 379: 1419-1427. doi:10.1016/S0140-6736(11)61650-4. PubMed: 22494826.
43. Choudhary N, Gupta P (2012) Vitamin D supplementation for severe pneumonia - a randomized controlled trial. Indian Pediatr 49: 449-454. doi:10.1007/s13312-012-0073-x. PubMed: 21992858.
44. Martineau AR, Timms PM, Bothamley GH, Hanifa Y, Islam K et al. (2011) High-dose vitamin D(3) during intensive-phase antimicrobial treatment of pulmonary tuberculosis: a double-blind randomised controlled trial. Lancet 377: 242-250. doi:10.1016/S0140-6736(10)61889-2. PubMed: 21215445.
45. Wejse C, Gomes VF, Rabna P, Gustafson P, Aaby P et al. (2009) Vitamin D as supplementary treatment for tuberculosis: a double-blind, randomized, placebo-controlled trial. Am J Respir Crit Care Med 179: 843-850. doi:10.1164/rccm.200804-567OC. PubMed: 19179490.
46. Salahuddin N, Ali F, Hasan Z, Rao N, Aqeel M et al. (2013) Vitamin D accelerates clinical recovery from tuberculosis: results of the SUCCINCT Study [Supplementary Cholecalciferol in recovery from tuberculosis]. A randomized, placebo-controlled, clinical trial of vitamin D supplementation in patients with pulmonary tuberculosis. BMC Infect Dis 13: 22. doi:10.1186/1471-2334-13-22. PubMed: 23331510.
47. Platz EA, Leitzmann MF, Hollis BW, Willett WC, Giovannucci E (2004) Plasma 1,25-dihydroxy- and 25-hydroxyvitamin D and subsequent risk of prostate cancer. Cancer Causes Control 15: 255-265. doi:10.1023/B:CACO.0000024245.24880. 8a. PubMed: 15090720. (Pubitemid 38988034)
48. Quraishi SA, Camargo CA Jr. (2012) Vitamin D in acute stress and critical illness. Curr Opin Clin Nutr Metab Care 15: 625-634. doi:10.1097/MCO. 0b013e328358fc2b. PubMed: 23075939.
49. Watt JP, Moïsi JC, Donaldson RL, Reid R, Ferro S et al. (2010) Measuring the incidence of adult community-acquired pneumonia in a Native American community. Epidemiol Infect 138: 1146-1154. doi:10.1017/ S0950268809991464. PubMed: 20056013.
50. Burton DC, Flannery B, Bennett NM, Farley MM, Gershman K et al. (2010) Socioeconomic and racial/ethnic disparities in the incidence of bacteremic pneumonia among US adults. Am J Public Health 100: 1904-1911. doi:10.2105/AJPH.2009.181313. PubMed: 20724687.