Clinical utility of a circulating tumor cell assay in Merkel cell carcinoma

Journal of the American Academy of Dermatology

Volumn 70, Issue 3, 2014, Pages 449-455

  Blom, Astrid ^a   Bhatia, Shailender ^a   Pietromonaco, Stephanie ^a   Koehler, Karen ^a   Iyer, Jayasri G ^a   Nagase, Kotaro ^a   Paulson, Kelly ^a   Sabath, Daniel E ^a   Nghiem, Paul ^a  

^a UNIVERSITY OF WASHINGTON   (United States)

Author keywords

biomarker; circulating tumor cells; dot like cytokeratin; Merkel cell carcinoma; neuroendocrine carcinoma of the skin; prognosis

Indexed keywords

BIOMARKER; CIRCULATING TUMOR CELLS; DOT-LIKE CYTOKERATIN; MERKEL CELL CARCINOMA; NEUROENDOCRINE CARCINOMA OF THE SKIN; PROGNOSIS;

ADULT; AGED; AGED, 80 AND OVER; ANALYSIS OF VARIANCE; BIOLOGICAL MARKERS; CARCINOMA, MERKEL CELL; DISEASE-FREE SURVIVAL; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; KAPLAN-MEIER ESTIMATE; KERATINS; LONGITUDINAL STUDIES; MALE; MIDDLE AGED; NEOPLASM INVASIVENESS; NEOPLASM RECURRENCE, LOCAL; NEOPLASM STAGING; NEOPLASTIC CELLS, CIRCULATING; PROGNOSIS; RISK ASSESSMENT; SKIN NEOPLASMS; STATISTICS, NONPARAMETRIC; SURVIVAL ANALYSIS;

EID: 84894089939     PISSN: 01909622     EISSN: 10976787     Source Type: Journal    
DOI: 10.1016/j.jaad.2013.10.051     Document Type: Article

References (27)

1. B.D. Lemos, B.E. Storer, J.G. Iyer, J.L. Phillips, C.K. Bichakjian, and L.C. Fang et al. Pathologic nodal evaluation improves prognostic accuracy in Merkel cell carcinoma: analysis of 5823 cases as the basis of the first consensus staging system J Am Acad Dermatol 63 2010 751 761
2. J.A. Santamaria-Barria, G.M. Boland, B.Y. Yeap, V. Nardi, D. Dias-Santagata, and J.C. Cusack Jr. Merkel cell carcinoma: 30-year experience from a single institution Ann Surg Oncol 20 2013 1365 1373
3. J. Albores-Saavedra, K. Batich, F. Chable-Montero, N. Sagy, A.M. Schwartz, and D.E. Henson Merkel cell carcinoma demographics, morphology, and survival based on 3870 cases: a population-based study J Cutan Pathol 37 2010 20 27
4. M. Heath, N. Jaimes, B. Lemos, A. Mostaghimi, L.C. Wang, and P.F. Penas et al. Clinical characteristics of Merkel cell carcinoma at diagnosis in 195 patients: the AEIOU features J Am Acad Dermatol 58 2008 375 381 (Pubitemid 351226308)
5. H. Feng, M. Shuda, Y. Chang, and P.S. Moore Clonal integration of a polyomavirus in human Merkel cell carcinoma Science 319 2008 1096 1100 (Pubitemid 351300792)
6. K.G. Paulson, J.J. Carter, L.G. Johnson, K.W. Cahill, J.G. Iyer, and D. Schrama et al. Antibodies to Merkel cell polyomavirus T antigen oncoproteins reflect tumor burden in Merkel cell carcinoma patients Cancer Res 70 2010 8388 8397
7. E.B. Hawryluk, K.N. O'Regan, N. Sheehy, Y. Guo, A. Dorosario, and C.G. Sakellis et al. Positron emission tomography/computed tomography imaging in Merkel cell carcinoma: a study of 270 scans in 97 patients at the Dana-Farber/Brigham and Women's Cancer Center J Am Acad Dermatol 68 2013 592 599
8. D. Olmos, H.T. Arkenau, J.E. Ang, I. Ledaki, G. Attard, and C.P. Carden et al. Circulating tumor cell (CTC) counts as intermediate end points in castration-resistant prostate cancer (CRPC): a single-centre experience Ann Oncol 20 2009 27 33
9. B.P. Negin, and S.J. Cohen Circulating tumor cells in colorectal cancer: past, present, and future challenges Curr Treat Options Oncol 11 2010 1 13
10. M.C. Liu, P.G. Shields, R.D. Warren, P. Cohen, M. Wilkinson, and Y.L. Ottaviano et al. Circulating tumor cells: a useful predictor of treatment efficacy in metastatic breast cancer J Clin Oncol 27 2009 5153 5159
11. A. Poveda, S.B. Kaye, R. McCormack, S. Wang, T. Parekh, and D. Ricci et al. Circulating tumor cells predict progression free survival and overall survival in patients with relapsed/recurrent advanced ovarian cancer Gynecol Oncol 122 2011 567 572
12. T. Kurihara, T. Itoi, A. Sofuni, F. Itokawa, T. Tsuchiya, and S. Tsuji et al. Detection of circulating tumor cells in patients with pancreatic cancer: a preliminary result J Hepatobiliary Pancreat Surg 15 2008 189 195 (Pubitemid 351516978)
13. M.S. Khan, T. Tsigani, M. Rashid, J.S. Rabouhans, D. Yu, and T.V. Luong et al. Circulating tumor cells and EpCAM expression in neuroendocrine tumors Clin Cancer Res 17 2011 337 345
14. M.Z. Qiu, Z.H. Li, Z.W. Zhou, Y.H. Li, Z.Q. Wang, and F.H. Wang et al. Detection of carcinoembryonic antigen messenger RNA in blood using quantitative real-time reverse transcriptase-polymerase chain reaction to predict recurrence of gastric adenocarcinoma J Transl Med 8 2010 107
15. K. Pachmann, O. Camara, A. Kohlhase, C. Rabenstein, T. Kroll, and I.B. Runnebaum et al. Assessing the efficacy of targeted therapy using circulating epithelial tumor cells (CETC): the example of SERM therapy monitoring as a unique tool to individualize therapy J Cancer Res Clin Oncol 137 2011 821 828
16. C.S. Tam, P. Turner, C. McLean, S. Whitehead, and M. Cole-Sinclair 'Leukemic' presentation of metastatic Merkel cell carcinoma Br J Haematol 129 2005 446 (Pubitemid 40646907)
17. I. Nemoto, K.C. Sato-Matsumura, Y. Fujita, K. Natsuga, H. Ujiie, and Y. Tomita et al. Leukemic dissemination of Merkel cell carcinoma in a patient with systemic lupus erythematosus Clin Exp Dermatol 33 2008 270 272 (Pubitemid 351550622)
18. K. Koyanagi, S.J. O'Day, P. Boasberg, M.B. Atkins, H.J. Wang, and R. Gonzalez et al. Serial monitoring of circulating tumor cells predicts outcome of induction biochemotherapy plus maintenance biotherapy for metastatic melanoma Clin Cancer Res 16 2010 2402 2408
19. M. Cristofanilli, G.T. Budd, M.J. Ellis, A. Stopeck, J. Matera, and M.C. Miller et al. Circulating tumor cells, disease progression, and survival in metastatic breast cancer N Engl J Med 351 2004 781 791 (Pubitemid 39095313)
20. S.G. Gupta, L.C. Wang, P.F. Penas, M. Gellenthin, S.J. Lee, and P. Nghiem Sentinel lymph node biopsy for evaluation and treatment of patients with Merkel cell carcinoma: the Dana-Farber experience and meta-analysis of the literature Arch Dermatol 142 2006 685 690
21. C. Alix-Panabieres, S. Riethdorf, and K. Pantel Circulating tumor cells and bone marrow micrometastasis Clin Cancer Res 14 2008 5013 5021
22. M. Mego, U. De Giorgi, L. Hsu, N.T. Ueno, V. Valero, and S. Jackson et al. Circulating tumor cells in metastatic inflammatory breast cancer Ann Oncol 20 2009 1824 1828
23. O.B. Goodman Jr., L.M. Fink, J.T. Symanowski, B. Wong, B. Grobaski, and D. Pomerantz et al. Circulating tumor cells in patients with castration-resistant prostate cancer baseline values and correlation with prognostic factors Cancer Epidemiol Biomarkers Prev 18 2009 1904 1913
24. F. Nole, E. Munzone, L. Zorzino, I. Minchella, M. Salvatici, and E. Botteri et al. Variation of circulating tumor cell levels during treatment of metastatic breast cancer: prognostic and therapeutic implications Ann Oncol 19 2008 891 897 (Pubitemid 351627303)
25. K. Hiraiwa, H. Takeuchi, H. Hasegawa, Y. Saikawa, K. Suda, and T. Ando et al. Clinical significance of circulating tumor cells in blood from patients with gastrointestinal cancers Ann Surg Oncol 15 2008 3092 3100
26. H.C. Laude, B. Jonchere, E. Maubec, A. Carlotti, E. Marinho, and B. Couturaud et al. Distinct Merkel cell polyomavirus molecular features in tumor and non tumor specimens from patients with Merkel cell carcinoma PLoS Pathog 6 2010 e1001076
27. T.A. Yap, D. Olmos, A.T. Brunetto, N. Tunariu, J. Barriuso, and R. Riisnaes et al. Phase I trial of a selective c-MET inhibitor ARQ 197 incorporating proof of mechanism pharmacodynamic studies J Clin Oncol 29 2011 1271 1279