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Volumn 11, Issue 1-2, 2010, Pages 1-13

Circulating tumor cells in colorectal cancer: Past, present, and future challenges

Author keywords

[No Author keywords available]

Indexed keywords

BEVACIZUMAB; CAPECITABINE; CETUXIMAB; EPIDERMAL GROWTH FACTOR RECEPTOR ANTIBODY; FLUOROPYRIMIDINE; FLUOROURACIL; FOLINIC ACID; IRINOTECAN; OXALIPLATIN; PANITUMUMAB; RECEPTOR ANTIBODY; SOMATOMEDIN C RECEPTOR ANTIBODY; UNCLASSIFIED DRUG;

EID: 75949111131     PISSN: 15272729     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11864-010-0115-3     Document Type: Review
Times cited : (92)

References (48)
  • 1
    • 41349099104 scopus 로고    scopus 로고
    • Cancer statistics, 2008
    • 10.3322/CA.2007.0010 18287387
    • A Jemal, et al. 2008 Cancer statistics, 2008 CA Cancer J Clin 58 2 71 96 10.3322/CA.2007.0010 18287387
    • (2008) CA Cancer J Clin , vol.58 , Issue.2 , pp. 71-96
    • Jemal, A.1
  • 2
    • 49049105525 scopus 로고    scopus 로고
    • Safety and efficacy of oxaliplatin and fluoropyrimidine regimens with or without bevacizumab as first-line treatment of metastatic colorectal cancer: Results of the TREE Study
    • 10.1200/JCO.2007.15.4138 18640933
    • HS Hochster, et al. 2008 Safety and efficacy of oxaliplatin and fluoropyrimidine regimens with or without bevacizumab as first-line treatment of metastatic colorectal cancer: results of the TREE Study J Clin Oncol 26 21 3523 3529 10.1200/JCO.2007.15.4138 18640933
    • (2008) J Clin Oncol , vol.26 , Issue.21 , pp. 3523-3529
    • Hochster, H.S.1
  • 3
    • 57449096129 scopus 로고    scopus 로고
    • Five-year data and prognostic factor analysis of oxaliplatin and irinotecan combinations for advanced colorectal cancer: N9741
    • 10.1200/JCO.2008.17.7147 19001325
    • HK Sanoff, et al. 2008 Five-year data and prognostic factor analysis of oxaliplatin and irinotecan combinations for advanced colorectal cancer: N9741 J Clin Oncol 26 35 5721 5727 10.1200/JCO.2008.17.7147 19001325
    • (2008) J Clin Oncol , vol.26 , Issue.35 , pp. 5721-5727
    • Sanoff, H.K.1
  • 4
    • 1342290189 scopus 로고    scopus 로고
    • FOLFIRI followed by FOLFOX6 or the reverse sequence in advanced colorectal cancer: A randomized GERCOR study
    • 10.1200/JCO.2004.05.113 14657227
    • C Tournigand, et al. 2004 FOLFIRI followed by FOLFOX6 or the reverse sequence in advanced colorectal cancer: a randomized GERCOR study J Clin Oncol 22 2 229 237 10.1200/JCO.2004.05.113 14657227
    • (2004) J Clin Oncol , vol.22 , Issue.2 , pp. 229-237
    • Tournigand, C.1
  • 5
    • 63849088630 scopus 로고    scopus 로고
    • Cetuximab and chemotherapy as initial treatment for metastatic colorectal cancer
    • 10.1056/NEJMoa0805019 19339720
    • E Van Cutsem, et al. 2009 Cetuximab and chemotherapy as initial treatment for metastatic colorectal cancer N Engl J Med 360 14 1408 1417 10.1056/NEJMoa0805019 19339720
    • (2009) N Engl J Med , vol.360 , Issue.14 , pp. 1408-1417
    • Van Cutsem, E.1
  • 6
    • 42649145667 scopus 로고    scopus 로고
    • Wild-type KRAS is required for panitumumab efficacy in patients with metastatic colorectal cancer
    • 10.1200/JCO.2007.14.7116 18316791
    • RG Amado, et al. 2008 Wild-type KRAS is required for panitumumab efficacy in patients with metastatic colorectal cancer J Clin Oncol 26 10 1626 1634 10.1200/JCO.2007.14.7116 18316791
    • (2008) J Clin Oncol , vol.26 , Issue.10 , pp. 1626-1634
    • Amado, R.G.1
  • 7
    • 51649120733 scopus 로고    scopus 로고
    • KRAS status and efficacy in the first-line treatment of patients with metastatic colorectal cancer (mCRC) treated with FOLFIRI with or without cetuximab: The CRYSTAL experience
    • 26(May 20 abstr 2
    • Van Cutsem E, et al.: KRAS status and efficacy in the first-line treatment of patients with metastatic colorectal cancer (mCRC) treated with FOLFIRI with or without cetuximab: the CRYSTAL experience. J Clin Oncol, 2008, 26(May 20 suppl; abstr 2)
    • (2008) J Clin Oncol , Issue.SUPPL.
    • Van Cutsem, E.1
  • 8
    • 70449714461 scopus 로고    scopus 로고
    • FOLFOXIRI (irinotecan, oxaliplatin, and infusional 5FU/LV) in combination with bevacizumab (BV) in the first-line treatment of metastatic colorectal cancer (mCRC): A phase II study by the G.O.N.O. group
    • 26(May 20 suppl; abstr 4031)
    • Falcone A, et al.: FOLFOXIRI (irinotecan, oxaliplatin, and infusional 5FU/LV) in combination with bevacizumab (BV) in the first-line treatment of metastatic colorectal cancer (mCRC): a phase II study by the G.O.N.O. group. J Clin Oncol, 2008, 26(May 20 suppl; abstr 4031)
    • (2008) J Clin Oncol
    • Falcone, A.1
  • 10
    • 0029738486 scopus 로고    scopus 로고
    • Molecular and immunological detection of circulating tumor cells and micrometastases from solid tumors
    • 8787692
    • TJ Pelkey HF Frierson Jr DE Bruns 1996 Molecular and immunological detection of circulating tumor cells and micrometastases from solid tumors Clin Chem 42 9 1369 1381 8787692
    • (1996) Clin Chem , vol.42 , Issue.9 , pp. 1369-1381
    • Pelkey, T.J.1    Frierson, Jr.H.F.2    Bruns, D.E.3
  • 11
    • 0032516046 scopus 로고    scopus 로고
    • Detection and characterization of carcinoma cells in the blood
    • 10.1073/pnas.95.8.4589 9539782
    • E Racila, et al. 1998 Detection and characterization of carcinoma cells in the blood Proc Natl Acad Sci USA 95 8 4589 4594 10.1073/pnas.95.8.4589 9539782
    • (1998) Proc Natl Acad Sci USA , vol.95 , Issue.8 , pp. 4589-4594
    • Racila, E.1
  • 12
    • 64749109611 scopus 로고    scopus 로고
    • Circulating cell death products predict clinical outcome of colorectal cancer patients
    • 10.1186/1471-2407-9-88 19302716
    • PJ Koelink, et al. 2009 Circulating cell death products predict clinical outcome of colorectal cancer patients BMC Cancer 9 88 10.1186/1471-2407-9-88 19302716
    • (2009) BMC Cancer , vol.9 , pp. 88
    • Koelink, P.J.1
  • 13
    • 33846444679 scopus 로고    scopus 로고
    • Role of circulating tumour cells in predicting recurrence after excision of primary colorectal carcinoma
    • 10.1002/bjs.5526 17058316
    • TG Allen-Mersh, et al. 2007 Role of circulating tumour cells in predicting recurrence after excision of primary colorectal carcinoma Br J Surg 94 1 96 105 10.1002/bjs.5526 17058316
    • (2007) Br J Surg , vol.94 , Issue.1 , pp. 96-105
    • Allen-Mersh, T.G.1
  • 14
    • 0031951878 scopus 로고    scopus 로고
    • Expression of prostate-specific antigen and prostate-specific membrane antigen transcripts in blood cells: Implications for the detection of hematogenous prostate cells and standardization
    • 9510850
    • JL Gala, et al. 1998 Expression of prostate-specific antigen and prostate-specific membrane antigen transcripts in blood cells: implications for the detection of hematogenous prostate cells and standardization Clin Chem 44 3 472 481 9510850
    • (1998) Clin Chem , vol.44 , Issue.3 , pp. 472-481
    • Gala, J.L.1
  • 15
    • 0029038764 scopus 로고
    • Prostate-specific antigen messenger RNA is expressed in non-prostate cells: Implications for detection of micrometastases
    • 7540108
    • MR Smith S Biggar M Hussain 1995 Prostate-specific antigen messenger RNA is expressed in non-prostate cells: implications for detection of micrometastases Cancer Res 55 12 2640 2644 7540108
    • (1995) Cancer Res , vol.55 , Issue.12 , pp. 2640-2644
    • Smith, M.R.1    Biggar, S.2    Hussain, M.3
  • 16
    • 0342547344 scopus 로고    scopus 로고
    • Minimal illegitimate levels of cytokeratin K19 expression in mononucleated blood cells detected by a reverse transcription PCR method (RT-PCR)
    • 10.1016/S0009-8981(97)00054-5 9247732
    • JA Lopez-Guerrero, et al. 1997 Minimal illegitimate levels of cytokeratin K19 expression in mononucleated blood cells detected by a reverse transcription PCR method (RT-PCR) Clin Chim Acta 263 1 105 116 10.1016/S0009-8981(97)00054-5 9247732
    • (1997) Clin Chim Acta , vol.263 , Issue.1 , pp. 105-116
    • Lopez-Guerrero, J.A.1
  • 17
    • 1142310557 scopus 로고    scopus 로고
    • Molecular detection of circulating cancer cells. Role in diagnosis, prognosis and follow-up of colon cancer patients
    • 10.1159/000075355 14752222
    • B Molnar, et al. 2003 Molecular detection of circulating cancer cells. Role in diagnosis, prognosis and follow-up of colon cancer patients Dig Dis 21 4 320 325 10.1159/000075355 14752222
    • (2003) Dig Dis , vol.21 , Issue.4 , pp. 320-325
    • Molnar, B.1
  • 18
    • 0035678088 scopus 로고    scopus 로고
    • Circulating tumor cell clusters in the peripheral blood of colorectal cancer patients
    • 11751505
    • B Molnar, et al. 2001 Circulating tumor cell clusters in the peripheral blood of colorectal cancer patients Clin Cancer Res 7 12 4080 4085 11751505
    • (2001) Clin Cancer Res , vol.7 , Issue.12 , pp. 4080-4085
    • Molnar, B.1
  • 19
    • 0036091226 scopus 로고    scopus 로고
    • Detection of circulating cytokeratin-positive cells in the blood of breast cancer patients using immunomagnetic enrichment and digital microscopy
    • 12006523
    • TE Witzig, et al. 2002 Detection of circulating cytokeratin-positive cells in the blood of breast cancer patients using immunomagnetic enrichment and digital microscopy Clin Cancer Res 8 5 1085 1091 12006523
    • (2002) Clin Cancer Res , vol.8 , Issue.5 , pp. 1085-1091
    • Witzig, T.E.1
  • 20
    • 6044259206 scopus 로고    scopus 로고
    • Tumor cells circulate in the peripheral blood of all major carcinomas but not in healthy subjects or patients with nonmalignant diseases
    • 10.1158/1078-0432.CCR-04-0378 15501967
    • WJ Allard, et al. 2004 Tumor cells circulate in the peripheral blood of all major carcinomas but not in healthy subjects or patients with nonmalignant diseases Clin Cancer Res 10 20 6897 6904 10.1158/1078-0432.CCR-04-0378 15501967
    • (2004) Clin Cancer Res , vol.10 , Issue.20 , pp. 6897-6904
    • Allard, W.J.1
  • 21
    • 33749031540 scopus 로고    scopus 로고
    • Isolation and characterization of circulating tumor cells in patients with metastatic colorectal cancer
    • 10.3816/CCC.2006.n.029 16945168
    • SJ Cohen, et al. 2006 Isolation and characterization of circulating tumor cells in patients with metastatic colorectal cancer Clin Colorectal Cancer 6 2 125 132 10.3816/CCC.2006.n.029 16945168
    • (2006) Clin Colorectal Cancer , vol.6 , Issue.2 , pp. 125-132
    • Cohen, S.J.1
  • 22
    • 49249130844 scopus 로고    scopus 로고
    • Relationship of circulating tumor cells to tumor response, progression-free survival, and overall survival in patients with metastatic colorectal cancer
    • 10.1200/JCO.2007.15.8923 18591556
    • SJ Cohen, et al. 2008 Relationship of circulating tumor cells to tumor response, progression-free survival, and overall survival in patients with metastatic colorectal cancer J Clin Oncol 26 19 3213 3221 10.1200/JCO.2007.15. 8923 18591556
    • (2008) J Clin Oncol , vol.26 , Issue.19 , pp. 3213-3221
    • Cohen, S.J.1
  • 23
    • 77956229570 scopus 로고    scopus 로고
    • Circulating tumor cells (CTC) in newly diagnosed breast or colorectal cancers
    • 18S: June 20 Suppl: abstr 14512
    • Groot M, et al.: Circulating tumor cells (CTC) in newly diagnosed breast or colorectal cancers. J Clin Oncol 2007, 25(18S: June 20 Suppl: abstr 14512)
    • (2007) J Clin Oncol , vol.25
    • Groot, M.1
  • 24
    • 55149111852 scopus 로고    scopus 로고
    • Clinical significance of circulating tumor cells in blood from patients with gastrointestinal cancers
    • 10.1245/s10434-008-0122-9 18766405
    • K Hiraiwa, et al. 2008 Clinical significance of circulating tumor cells in blood from patients with gastrointestinal cancers Ann Surg Oncol 15 11 3092 3100 10.1245/s10434-008-0122-9 18766405
    • (2008) Ann Surg Oncol , vol.15 , Issue.11 , pp. 3092-3100
    • Hiraiwa, K.1
  • 25
    • 43049137717 scopus 로고    scopus 로고
    • Circulating tumor cells in colorectal cancer: Correlation with clinical and pathological variables
    • 10.1093/annonc/mdm583 18212090
    • J Sastre, et al. 2008 Circulating tumor cells in colorectal cancer: correlation with clinical and pathological variables Ann Oncol 19 5 935 938 10.1093/annonc/mdm583 18212090
    • (2008) Ann Oncol , vol.19 , Issue.5 , pp. 935-938
    • Sastre, J.1
  • 26
    • 4143094988 scopus 로고    scopus 로고
    • Circulating tumor cells, disease progression, and survival in metastatic breast cancer
    • 10.1056/NEJMoa040766 15317891
    • M Cristofanilli, et al. 2004 Circulating tumor cells, disease progression, and survival in metastatic breast cancer N Engl J Med 351 8 781 791 10.1056/NEJMoa040766 15317891
    • (2004) N Engl J Med , vol.351 , Issue.8 , pp. 781-791
    • Cristofanilli, M.1
  • 27
    • 0034867029 scopus 로고    scopus 로고
    • Changes in circulating carcinoma cells in patients with metastatic prostate cancer correlate with disease status
    • 10.1016/S0090-4295(01)01191-8 11549486
    • JG Moreno, et al. 2001 Changes in circulating carcinoma cells in patients with metastatic prostate cancer correlate with disease status Urology 58 3 386 392 10.1016/S0090-4295(01)01191-8 11549486
    • (2001) Urology , vol.58 , Issue.3 , pp. 386-392
    • Moreno, J.G.1
  • 28
    • 3242714769 scopus 로고    scopus 로고
    • A rare-cell detector for cancer
    • 10.1073/pnas.0404036101 15249663
    • RT Krivacic, et al. 2004 A rare-cell detector for cancer Proc Natl Acad Sci USA 101 29 10501 10504 10.1073/pnas.0404036101 15249663
    • (2004) Proc Natl Acad Sci USA , vol.101 , Issue.29 , pp. 10501-10504
    • Krivacic, R.T.1
  • 29
    • 37549002543 scopus 로고    scopus 로고
    • Isolation of rare circulating tumour cells in cancer patients by microchip technology
    • 10.1038/nature06385 18097410
    • S Nagrath, et al. 2007 Isolation of rare circulating tumour cells in cancer patients by microchip technology Nature 450 7173 1235 1239 10.1038/nature06385 18097410
    • (2007) Nature , vol.450 , Issue.7173 , pp. 1235-1239
    • Nagrath, S.1
  • 30
    • 47949114668 scopus 로고    scopus 로고
    • Detection of mutations in EGFR in circulating lung-cancer cells
    • 10.1056/NEJMoa0800668 18596266
    • S Maheswaran, et al. 2008 Detection of mutations in EGFR in circulating lung-cancer cells N Engl J Med 359 4 366 377 10.1056/NEJMoa0800668 18596266
    • (2008) N Engl J Med , vol.359 , Issue.4 , pp. 366-377
    • Maheswaran, S.1
  • 31
    • 67650354361 scopus 로고    scopus 로고
    • Prognostic significance of circulating tumor cells in patients with metastatic colorectal cancer
    • Cohen SJ, et al.: Prognostic significance of circulating tumor cells in patients with metastatic colorectal cancer. Ann Oncol 2009, 20(7):1223-1229.
    • (2009) Ann Oncol , vol.20 , Issue.7 , pp. 1223-1229
    • Cohen, S.J.1
  • 32
    • 59749091477 scopus 로고    scopus 로고
    • Chemotherapy, bevacizumab, and cetuximab in metastatic colorectal cancer
    • 10.1056/NEJMoa0808268 19196673
    • J Tol, et al. 2009 Chemotherapy, bevacizumab, and cetuximab in metastatic colorectal cancer N Engl J Med 360 6 563 572 10.1056/NEJMoa0808268 19196673
    • (2009) N Engl J Med , vol.360 , Issue.6 , pp. 563-572
    • Tol, J.1
  • 33
    • 75449113324 scopus 로고    scopus 로고
    • Circulating tumor cells (CTC) in advanced colorectal cancer (ACC) patients undergoing 1st line treatment with chemotherapy, bevacizumab and cetuximab as an important and early predictor of survival
    • viii 166
    • Koopman M, et al.: Circulating tumor cells (CTC) in advanced colorectal cancer (ACC) patients undergoing 1st line treatment with chemotherapy, bevacizumab and cetuximab as an important and early predictor of survival. Ann Oncol 2008, 19(suppl 8: viii 166)
    • (2008) Ann Oncol , vol.19 , Issue.SUPPL. 8
    • Koopman, M.1
  • 34
    • 61349185243 scopus 로고    scopus 로고
    • Clinical significance of cytokeratin 20-positive circulating tumor cells detected by a refined immunomagnetic enrichment assay in colorectal cancer patients
    • 10.1158/1078-0432.CCR-08-1515 19188172
    • SC Wong, et al. 2009 Clinical significance of cytokeratin 20-positive circulating tumor cells detected by a refined immunomagnetic enrichment assay in colorectal cancer patients Clin Cancer Res 15 3 1005 1012 10.1158/1078-0432. CCR-08-1515 19188172
    • (2009) Clin Cancer Res , vol.15 , Issue.3 , pp. 1005-1012
    • Wong, S.C.1
  • 35
    • 77956224946 scopus 로고    scopus 로고
    • Use of circulating tumor cells and circulating endothelial cells as surrogate markers for FOLFOX4 with or without bevacizumab in mCRC
    • abstr 345
    • Matsusaka S, et al.: Use of circulating tumor cells and circulating endothelial cells as surrogate markers for FOLFOX4 with or without bevacizumab in mCRC. ASCO Gastrointestinal Cancers Symp, 2009 (abstr 345)
    • (2009) ASCO Gastrointestinal Cancers Symp
    • Matsusaka, S.1
  • 36
    • 2542561964 scopus 로고    scopus 로고
    • Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer
    • 10.1056/NEJMoa032691 15175435
    • H Hurwitz, et al. 2004 Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer N Engl J Med 350 23 2335 2342 10.1056/NEJMoa032691 15175435
    • (2004) N Engl J Med , vol.350 , Issue.23 , pp. 2335-2342
    • Hurwitz, H.1
  • 37
    • 34249000361 scopus 로고    scopus 로고
    • Phase III trial of infusional fluorouracil, leucovorin, oxaliplatin, and irinotecan (FOLFOXIRI) compared with infusional fluorouracil, leucovorin, and irinotecan (FOLFIRI) as first-line treatment for metastatic colorectal cancer: The Gruppo Oncologico Nord Ovest
    • 10.1200/JCO.2006.09.0928 17470860
    • A Falcone, et al. 2007 Phase III trial of infusional fluorouracil, leucovorin, oxaliplatin, and irinotecan (FOLFOXIRI) compared with infusional fluorouracil, leucovorin, and irinotecan (FOLFIRI) as first-line treatment for metastatic colorectal cancer: the Gruppo Oncologico Nord Ovest J Clin Oncol 25 13 1670 1676 10.1200/JCO.2006.09.0928 17470860
    • (2007) J Clin Oncol , vol.25 , Issue.13 , pp. 1670-1676
    • Falcone, A.1
  • 38
    • 0033504042 scopus 로고    scopus 로고
    • Clinical score for predicting recurrence after hepatic resection for metastatic colorectal cancer: Analysis of 1001 consecutive cases
    • 10.1097/00000658-199909000-00004 10493478 discussion 318-321
    • Y Fong, et al. 1999 Clinical score for predicting recurrence after hepatic resection for metastatic colorectal cancer: analysis of 1001 consecutive cases Ann Surg 230 3 309 318 10.1097/00000658-199909000-00004 10493478 discussion 318-321
    • (1999) Ann Surg , vol.230 , Issue.3 , pp. 309-318
    • Fong, Y.1
  • 39
    • 77956226728 scopus 로고    scopus 로고
    • http://www.nccn.org/professionals/physician-gls/PDF/colon.pdf. Accessed March 11, 2009
  • 40
    • 40749149728 scopus 로고    scopus 로고
    • Perioperative chemotherapy with FOLFOX4 and surgery versus surgery alone for resectable liver metastases from colorectal cancer (EORTC Intergroup trial 40983): A randomised controlled trial
    • 10.1016/S0140-6736(08)60455-9 18358928
    • B Nordlinger, et al. 2008 Perioperative chemotherapy with FOLFOX4 and surgery versus surgery alone for resectable liver metastases from colorectal cancer (EORTC Intergroup trial 40983): a randomised controlled trial Lancet 371 9617 1007 1016 10.1016/S0140-6736(08)60455-9 18358928
    • (2008) Lancet , vol.371 , Issue.9617 , pp. 1007-1016
    • Nordlinger, B.1
  • 41
    • 2542615200 scopus 로고    scopus 로고
    • Oxaliplatin, fluorouracil, and leucovorin as adjuvant treatment for colon cancer
    • 10.1056/NEJMoa032709 15175436
    • T Andre, et al. 2004 Oxaliplatin, fluorouracil, and leucovorin as adjuvant treatment for colon cancer N Engl J Med 350 23 2343 2351 10.1056/NEJMoa032709 15175436
    • (2004) N Engl J Med , vol.350 , Issue.23 , pp. 2343-2351
    • Andre, T.1
  • 42
    • 69549147378 scopus 로고    scopus 로고
    • A phase III trial comparing mFOLFOX6 to mFOLFOX6 plus bevacizumab in stage II or III carcinoma of the colon: Results of NSABP Protocol C-08
    • abstr LBA4
    • Wolmark N, et al.: A phase III trial comparing mFOLFOX6 to mFOLFOX6 plus bevacizumab in stage II or III carcinoma of the colon: results of NSABP Protocol C-08. J Clin Oncol 2009, 27(18 suppl; abstr LBA4)
    • (2009) J Clin Oncol , vol.27 , Issue.18 SUPPL.
    • Wolmark, N.1
  • 43
    • 77749251731 scopus 로고    scopus 로고
    • A quantitative multigene RT-PCR assay for prediction of recurrence in stage II colon cancer: Selection of the genes in four large studies and results of the independent, prospectively designed QUASAR validation study
    • abstr 4000
    • Kerr D, et al.: A quantitative multigene RT-PCR assay for prediction of recurrence in stage II colon cancer: selection of the genes in four large studies and results of the independent, prospectively designed QUASAR validation study. J Clin Oncol 2009, 27(15 suppl; abstr 4000)
    • (2009) J Clin Oncol , vol.27 , Issue.15 SUPPL.
    • Kerr, D.1
  • 44
    • 34250783291 scopus 로고    scopus 로고
    • Potential applications for circulating tumor cells expressing the insulin-like growth factor-I receptor
    • 10.1158/1078-0432.CCR-07-0268 17575225
    • JS de Bono, et al. 2007 Potential applications for circulating tumor cells expressing the insulin-like growth factor-I receptor Clin Cancer Res 13 12 3611 3616 10.1158/1078-0432.CCR-07-0268 17575225
    • (2007) Clin Cancer Res , vol.13 , Issue.12 , pp. 3611-3616
    • De Bono, J.S.1
  • 45
    • 27744508000 scopus 로고    scopus 로고
    • Detection of cytokeratin 20 mRNA in the peripheral blood of patients with colorectal cancer by immunomagnetic bead enrichment and real-time reverse transcriptase-polymerase chain reaction
    • 10.1111/j.1440-1746.2005.03894.x 16048578
    • J Guo, et al. 2005 Detection of cytokeratin 20 mRNA in the peripheral blood of patients with colorectal cancer by immunomagnetic bead enrichment and real-time reverse transcriptase-polymerase chain reaction J Gastroenterol Hepatol 20 8 1279 1284 10.1111/j.1440-1746.2005.03894.x 16048578
    • (2005) J Gastroenterol Hepatol , vol.20 , Issue.8 , pp. 1279-1284
    • Guo, J.1
  • 46
    • 77956231826 scopus 로고    scopus 로고
    • EGFR staining of circulating tumor cells (CTCs) from patients with metastatic colorectal cancer
    • abstr 373
    • Lim HJ, et al.: EGFR staining of circulating tumor cells (CTCs) from patients with metastatic colorectal cancer. ASCO Gastrointestinal Cancers Symp 2009 (abstr 373)
    • (2009) ASCO Gastrointestinal Cancers Symp
    • Lim, H.J.1
  • 47
    • 34147103678 scopus 로고    scopus 로고
    • Open-label phase III trial of panitumumab plus best supportive care compared with best supportive care alone in patients with chemotherapy- refractory metastatic colorectal cancer
    • 10.1200/JCO.2006.08.1620 17470858
    • E Van Cutsem, et al. 2007 Open-label phase III trial of panitumumab plus best supportive care compared with best supportive care alone in patients with chemotherapy-refractory metastatic colorectal cancer J Clin Oncol 25 13 1658 1664 10.1200/JCO.2006.08.1620 17470858
    • (2007) J Clin Oncol , vol.25 , Issue.13 , pp. 1658-1664
    • Van Cutsem, E.1
  • 48
    • 77956230239 scopus 로고    scopus 로고
    • Modulation and prognostic value of epidermal growth factor receptor (EGFR) expression in circulating tumor cells (CTCs) during chemotherapy (CT) in patients with metastatic colorectal cancer
    • May 20 suppl; abstr 15038
    • Hendlisz A, et al.: Modulation and prognostic value of epidermal growth factor receptor (EGFR) expression in circulating tumor cells (CTCs) during chemotherapy (CT) in patients with metastatic colorectal cancer. J Clin Oncol 2008, 26(May 20 suppl; abstr 15038)
    • (2008) J Clin Oncol , vol.26
    • Hendlisz, A.1


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