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Volumn 21, Issue 2, 2014, Pages 102-113

Optimal approach for high-risk acute promyelocytic leukemia

Author keywords

Acute promyelocytic leukemia; All trans retinoic acid; Arsenic trioxide; Early death; Relapse; Risk stratification; Risk adapted therapy

Indexed keywords

ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; CONSOLIDATION CHEMOTHERAPY; HUMANS; INDUCTION CHEMOTHERAPY; LEUKEMIA, PROMYELOCYTIC, ACUTE; MAINTENANCE CHEMOTHERAPY; NEOPLASM RECURRENCE, LOCAL; RISK FACTORS; TREATMENT FAILURE; TREATMENT OUTCOME;

EID: 84894067674     PISSN: 10656251     EISSN: 15317048     Source Type: Journal    
DOI: 10.1097/MOH.0000000000000025     Document Type: Review
Times cited : (10)

References (100)
  • 1
    • 77955914238 scopus 로고    scopus 로고
    • Refinement of cytogenetic classification in acute myeloid leukemia: Determination of prognostic significance of rare recurring chromosomal abnormalities among 5876 younger adult patients treated in the United Kingdom Medical Research Council trials
    • Grimwade D, Hills RK, Moorman AV, et al. Refinement of cytogenetic classification in acute myeloid leukemia: determination of prognostic significance of rare recurring chromosomal abnormalities among 5876 younger adult patients treated in the United Kingdom Medical Research Council trials. Blood 2010; 116:354-365.
    • (2010) Blood , vol.116 , pp. 354-365
    • Grimwade, D.1    Hills, R.K.2    Moorman, A.V.3
  • 2
    • 85027932070 scopus 로고    scopus 로고
    • Continuing high early death rate in acute promyelocytic leukemia: A population-based report from the Swedish Adult Acute Leukemia Registry
    • Lehmann S, Ravn A, Carlsson L, et al. Continuing high early death rate in acute promyelocytic leukemia: a population-based report from the Swedish Adult Acute Leukemia Registry. Leukemia 2011; 25:1128-1134.
    • (2011) Leukemia , vol.25 , pp. 1128-1134
    • Lehmann, S.1    Ravn, A.2    Carlsson, L.3
  • 3
    • 0021345113 scopus 로고
    • Evidence for a 15;17 translocation in every patient with acute promyelocytic leukemia
    • Larson RA, Kondo K, Vardiman JW, et al. Evidence for a 15;17 translocation in every patient with acute promyelocytic leukemia. Am J Med 1984; 76:827-841.
    • (1984) Am J Med , vol.76 , pp. 827-841
    • Larson, R.A.1    Kondo, K.2    Vardiman, J.W.3
  • 4
    • 0025043959 scopus 로고
    • The t(15;17) translocation of acute promyelocytic leukaemia fuses the retinoic acid receptor alpha gene to a novel transcribed locus
    • de The H, Chomienne C, Lanotte M, et al. The t(15;17) translocation of acute promyelocytic leukaemia fuses the retinoic acid receptor alpha gene to a novel transcribed locus. Nature 1990; 347:558-561.
    • (1990) Nature , vol.347 , pp. 558-561
    • De The, H.1    Chomienne, C.2    Lanotte, M.3
  • 5
    • 0025780876 scopus 로고
    • Chromosomal translocation t(15;17) in human acute promyelocytic leukemia fuses RAR alpha with a novel putative transcription factor, PML
    • Kakizuka A, Miller WH Jr, Umesono K, et al. Chromosomal translocation t(15;17) in human acute promyelocytic leukemia fuses RAR alpha with a novel putative transcription factor, PML. Cell 1991; 66:663-674.
    • (1991) Cell , vol.66 , pp. 663-674
    • Kakizuka, A.1    Miller Jr., W.H.2    Umesono, K.3
  • 6
    • 34347384854 scopus 로고    scopus 로고
    • Treatment of acute promyelocytic leukaemia with all-trans retinoic acid and arsenic trioxide: A paradigm of synergistic molecular targeting therapy
    • Zhou G-B, Zhang J, Wang Z-Y, et al. Treatment of acute promyelocytic leukaemia with all-trans retinoic acid and arsenic trioxide: a paradigm of synergistic molecular targeting therapy. Philos Trans R Soc Lond B Biol Sci 2007; 362:959-971.
    • (2007) Philos Trans R Soc Lond B Biol Sci , vol.362 , pp. 959-971
    • Zhou, G.-B.1    Zhang, J.2    Wang, Z.-Y.3
  • 7
    • 61949441174 scopus 로고    scopus 로고
    • Management of acute promyelocytic leukemia: Recommendations from an expert panel on behalf of the European LeukemiaNet
    • Sanz MA, Grimwade D, Tallman MS, et al. Management of acute promyelocytic leukemia: recommendations from an expert panel on behalf of the European LeukemiaNet. Blood 2009; 113:1875-1891.
    • (2009) Blood , vol.113 , pp. 1875-1891
    • Sanz, M.A.1    Grimwade, D.2    Tallman, M.S.3
  • 8
    • 0027258363 scopus 로고
    • Rearrangements of the retinoic acid receptor alpha and promyelocytic leukemia zinc finger genes resulting from t(11;17)(q23;q21) in a patient with acute promyelocytic leukemia
    • Chen SJ, Zelent A, Tong JH, et al. Rearrangements of the retinoic acid receptor alpha and promyelocytic leukemia zinc finger genes resulting from t(11;17)(q23;q21) in a patient with acute promyelocytic leukemia. J Clin Investig 1993; 91:2260-2267.
    • (1993) J Clin Investig , vol.91 , pp. 2260-2267
    • Chen, S.J.1    Zelent, A.2    Tong, J.H.3
  • 9
    • 0030022316 scopus 로고    scopus 로고
    • The t(5;17) variant of acute promyelocytic leukemia expresses a nucleophosmin-retinoic acid receptor fusion
    • Redner RL, Rush EA, Faas S, et al. The t(5;17) variant of acute promyelocytic leukemia expresses a nucleophosmin-retinoic acid receptor fusion. Blood 1996; 87:882-886.
    • (1996) Blood , vol.87 , pp. 882-886
    • Redner, R.L.1    Rush, E.A.2    Faas, S.3
  • 10
    • 0030771192 scopus 로고    scopus 로고
    • Fusion of retinoic acid receptor alpha to NuMA, the nuclear mitotic apparatus protein, by a variant translocation in acute promyelocytic leukaemia
    • Wells RA, Catzavelos C, Kamel-Reid S. Fusion of retinoic acid receptor alpha to NuMA, the nuclear mitotic apparatus protein, by a variant translocation in acute promyelocytic leukaemia. Nat Genet 1997; 17:109-113.
    • (1997) Nat Genet , vol.17 , pp. 109-113
    • Wells, R.A.1    Catzavelos, C.2    Kamel-Reid, S.3
  • 11
    • 0032867588 scopus 로고    scopus 로고
    • The signal transducer and activator of transcription STAT5b gene is a new partner of retinoic acid receptor alpha in acute promyelocytic-like leukaemia
    • Arnould C, Philippe C, Bourdon V, et al. The signal transducer and activator of transcription STAT5b gene is a new partner of retinoic acid receptor alpha in acute promyelocytic-like leukaemia. HumMol Genet 1999; 8:1741-1749.
    • (1999) HumMol Genet , vol.8 , pp. 1741-1749
    • Arnould, C.1    Philippe, C.2    Bourdon, V.3
  • 12
    • 37049011235 scopus 로고    scopus 로고
    • The PRKAR1A gene is fused to RARA in a new variant acute promyelocytic leukemia
    • Catalano A, Dawson MA, Somana K, et al. The PRKAR1A gene is fused to RARA in a new variant acute promyelocytic leukemia. Blood 2007; 110:4073-4076.
    • (2007) Blood , vol.110 , pp. 4073-4076
    • Catalano, A.1    Dawson, M.A.2    Somana, K.3
  • 13
    • 50849123755 scopus 로고    scopus 로고
    • The seventh pathogenic fusion gene FIP1L1-RARA was isolated from a t(4;17)-positive acute promyelocytic leukemia
    • Kondo T, Mori A, Darmanin S, et al. The seventh pathogenic fusion gene FIP1L1-RARA was isolated from a t(4;17)-positive acute promyelocytic leukemia. Haematologica 2008; 93:1414-1416.
    • (2008) Haematologica , vol.93 , pp. 1414-1416
    • Kondo, T.1    Mori, A.2    Darmanin, S.3
  • 14
    • 78549267880 scopus 로고    scopus 로고
    • BCOR as a novel fusion partner of retinoic acid receptor alpha in a t(X;17)(p11;q12) variant of acute promyelocytic leukemia
    • Yamamoto Y, Tsuzuki S, Tsuzuki M, et al. BCOR as a novel fusion partner of retinoic acid receptor alpha in a t(X;17)(p11;q12) variant of acute promyelocytic leukemia. Blood 2010; 116:4274-4283.
    • (2010) Blood , vol.116 , pp. 4274-4283
    • Yamamoto, Y.1    Tsuzuki, S.2    Tsuzuki, M.3
  • 15
    • 84874444231 scopus 로고    scopus 로고
    • OBFC2A/RARA: A novel fusion gene in variant acute promyelocytic leukemia
    • Won D, Shin SY, Park C-J, et al. OBFC2A/RARA: a novel fusion gene in variant acute promyelocytic leukemia. Blood 2013; 121:1432-1435.
    • (2013) Blood , vol.121 , pp. 1432-1435
    • Won, D.1    Shin, S.Y.2    Park, C.-J.3
  • 16
    • 84878661606 scopus 로고    scopus 로고
    • Uncoupling RARA transcriptional activation and degradation clarifies the bases for APL response to therapies
    • Ablain J, Leiva M, Peres L, et al. Uncoupling RARA transcriptional activation and degradation clarifies the bases for APL response to therapies. J Exp Med 2013; 210:647-653.
    • (2013) J Exp Med , vol.210 , pp. 647-653
    • Ablain, J.1    Leiva, M.2    Peres, L.3
  • 17
    • 0024519006 scopus 로고
    • Acute promyelocytic leukemia: Treatment results during a decade at Memorial Hospital
    • Cunningham I, Gee T, Reich L, et al. Acute promyelocytic leukemia: treatment results during a decade at Memorial Hospital. Blood 1989; 73:1116-1122.
    • (1989) Blood , vol.73 , pp. 1116-1122
    • Cunningham, I.1    Gee, T.2    Reich, L.3
  • 18
    • 0029131724 scopus 로고
    • Effect of aggressive daunomycin therapy on survival in acute promyelocytic leukemia
    • Head D, Kopecky KJ, Weick J, et al. Effect of aggressive daunomycin therapy on survival in acute promyelocytic leukemia. Blood 1995; 86:1717-1728.
    • (1995) Blood , vol.86 , pp. 1717-1728
    • Head, D.1    Kopecky, K.J.2    Weick, J.3
  • 19
    • 0036838645 scopus 로고    scopus 로고
    • Induction therapy with idarubicin alone significantly influences event-free survival duration in patients with newly diagnosed hypergranular acute promyelocytic leukemia: Final results of the GIMEMA randomized study LAP 0389 with 7 years of minimal follow-up
    • Avvisati G, Petti MC, Lo-Coco F, et al. Induction therapy with idarubicin alone significantly influences event-free survival duration in patients with newly diagnosed hypergranular acute promyelocytic leukemia: final results of the GIMEMA randomized study LAP 0389 with 7 years of minimal follow-up. Blood 2002; 100:3141-3146.
    • (2002) Blood , vol.100 , pp. 3141-3146
    • Avvisati, G.1    Petti, M.C.2    Lo-Coco, F.3
  • 20
    • 77954681398 scopus 로고    scopus 로고
    • Risk-adapted treatment of acute promyelocytic leukemia based on all-trans retinoic acid and anthracycline with addition of cytarabine in consolidation therapy for high-risk patients: Further improvements in treatment outcome
    • Sanz MA, Montesinos P, Rayon C, et al. Risk-adapted treatment of acute promyelocytic leukemia based on all-trans retinoic acid and anthracycline with addition of cytarabine in consolidation therapy for high-risk patients: further improvements in treatment outcome. Blood 2010; 115:5137-5146.
    • (2010) Blood , vol.115 , pp. 5137-5146
    • Sanz, M.A.1    Montesinos, P.2    Rayon, C.3
  • 21
    • 34247369329 scopus 로고    scopus 로고
    • Is cytarabine useful in the treatment of acute promyelocytic leukemia? Results of a randomized trial from the European Acute Promyelocytic Leukemia Group
    • Ades L, Chevret S, Raffoux E, et al. Is cytarabine useful in the treatment of acute promyelocytic leukemia? Results of a randomized trial from the European Acute Promyelocytic Leukemia Group. J Clin Oncol 2006; 24:5703-5710.
    • (2006) J Clin Oncol , vol.24 , pp. 5703-5710
    • Ades, L.1    Chevret, S.2    Raffoux, E.3
  • 22
    • 62549083523 scopus 로고    scopus 로고
    • Long-term efficacy and safety of all-trans retinoic acid/arsenic trioxide-based therapy in newly diagnosed acute promyelocytic leukemia
    • Hu J, Liu Y-F, Wu C-F, et al. Long-term efficacy and safety of all-trans retinoic acid/arsenic trioxide-based therapy in newly diagnosed acute promyelocytic leukemia. Proc Natl Acad Sci U S A 2009; 106:3342-3347.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 3342-3347
    • Hu, J.1    Liu, Y.-F.2    Wu, C.-F.3
  • 23
    • 84865427746 scopus 로고    scopus 로고
    • All-trans-retinoic acid, idarubicin, and IV arsenic trioxide as initial therapy in acute promyelocytic leukemia (APML4)
    • Iland HJ, Bradstock K, Supple SG, et al. All-trans-retinoic acid, idarubicin, and IV arsenic trioxide as initial therapy in acute promyelocytic leukemia (APML4). Blood 2012; 120:1570-1580.
    • (2012) Blood , vol.120 , pp. 1570-1580
    • Iland, H.J.1    Bradstock, K.2    Supple, S.G.3
  • 24
    • 0028899552 scopus 로고
    • Clinical and molecular characterization of a rare syndrome of acute promyelocytic leukemia associated with translocation (11;17)
    • Licht JD, Chomienne C, Goy A, et al. Clinical and molecular characterization of a rare syndrome of acute promyelocytic leukemia associated with translocation (11;17). Blood 1995; 85:1083-1094.
    • (1995) Blood , vol.85 , pp. 1083-1094
    • Licht, J.D.1    Chomienne, C.2    Goy, A.3
  • 25
    • 84870950950 scopus 로고    scopus 로고
    • Acute myeloid leukemia with translocation t(8;16) presents with features which mimic acute promyelocytic leukemia and is associated with poor prognosis
    • Diab A, Zickl L, Abdel-Wahab O, et al. Acute myeloid leukemia with translocation t(8;16) presents with features which mimic acute promyelocytic leukemia and is associated with poor prognosis. Leuk Res 2013; 37:32-36.
    • (2013) Leuk Res , vol.37 , pp. 32-36
    • Diab, A.1    Zickl, L.2    Abdel-Wahab, O.3
  • 26
    • 0033168768 scopus 로고    scopus 로고
    • Complete remission of t(11;17) positive acute promyelocytic leukemia induced by all-trans retinoic acid and granulocyte colony-stimulating factor
    • Jansen JH, de Ridder MC, Geertsma WM, et al. Complete remission of t(11;17) positive acute promyelocytic leukemia induced by all-trans retinoic acid and granulocyte colony-stimulating factor. Blood 1999; 94:39-45.
    • (1999) Blood , vol.94 , pp. 39-45
    • Jansen, J.H.1    De Ridder, M.C.2    Geertsma, W.M.3
  • 27
    • 84874456701 scopus 로고    scopus 로고
    • 8-CPT-cAMP/all-trans retinoic acid targets t(11;17) acute promyelocytic leukemia through enhanced cell differentiation and PLZF/RAR degradation
    • Jiao B, Ren Z-H, Liu P, et al. 8-CPT-cAMP/all-trans retinoic acid targets t(11;17) acute promyelocytic leukemia through enhanced cell differentiation and PLZF/RAR degradation. Proc Natl Acad Sci U S A 2013; 110:3495-3500.
    • (2013) Proc Natl Acad Sci U S A , vol.110 , pp. 3495-3500
    • Jiao, B.1    Ren, Z.-H.2    Liu, P.3
  • 28
    • 0001483546 scopus 로고
    • Acute promyelocytic leukemia
    • Hillestad LK. Acute promyelocytic leukemia. Acta Med Scand 1957; 159:189-194.
    • (1957) Acta Med Scand , vol.159 , pp. 189-194
    • Hillestad, L.K.1
  • 29
    • 77958499078 scopus 로고    scopus 로고
    • Front-line treatment of acute promyelocytic leukemia with AIDA induction followed by risk-adapted consolidation for adults younger than 61 years: Results of the AIDA-2000 trial of the GIMEMA Group
    • Lo-Coco F, Avvisati G, Vignetti M, et al. Front-line treatment of acute promyelocytic leukemia with AIDA induction followed by risk-adapted consolidation for adults younger than 61 years: results of the AIDA-2000 trial of the GIMEMA Group. Blood 2010; 116:3171-3179.
    • (2010) Blood , vol.116 , pp. 3171-3179
    • Lo-Coco, F.1    Avvisati, G.2    Vignetti, M.3
  • 30
    • 74049115852 scopus 로고    scopus 로고
    • High dose ara-C in the treatment of newly diagnosed acute promyelocytic leukemia: Long-term results of the German AMLCG
    • Lengfelder E, Haferlach C, Saussele S, et al. High dose ara-C in the treatment of newly diagnosed acute promyelocytic leukemia: long-term results of the German AMLCG. Leukemia 2009; 23:2248-2258.
    • (2009) Leukemia , vol.23 , pp. 2248-2258
    • Lengfelder, E.1    Haferlach, C.2    Saussele, S.3
  • 31
    • 77958456360 scopus 로고    scopus 로고
    • Arsenic trioxide improves event-free and overall survival for adults with acute promyelocytic leukemia: North American Leukemia Intergroup Study C9710
    • Powell BL, Moser B, Stock W, et al. Arsenic trioxide improves event-free and overall survival for adults with acute promyelocytic leukemia: North American Leukemia Intergroup Study C9710. Blood 2010; 116:3751-3757.
    • (2010) Blood , vol.116 , pp. 3751-3757
    • Powell, B.L.1    Moser, B.2    Stock, W.3
  • 32
    • 59149089411 scopus 로고    scopus 로고
    • Effective treatment of acute promyelocytic leukemia with all-trans-retinoic acid, arsenic trioxide, and gemtuzumab ozogamicin
    • Ravandi F, Estey E, Jones D, et al. Effective treatment of acute promyelocytic leukemia with all-trans-retinoic acid, arsenic trioxide, and gemtuzumab ozogamicin. J Clin Oncol 2009; 27:504-510.
    • (2009) J Clin Oncol , vol.27 , pp. 504-510
    • Ravandi, F.1    Estey, E.2    Jones, D.3
  • 33
    • 84869773108 scopus 로고    scopus 로고
    • Long term curative effects of sequential therapy with all-trans retinoic acid, arsenious oxide and chemotherapy on patients with acute promyelocytic leukemia
    • Pei R, Cao J, Ma J, et al. Long term curative effects of sequential therapy with all-trans retinoic acid, arsenious oxide and chemotherapy on patients with acute promyelocytic leukemia. Hematology 2012; 17:311-316.
    • (2012) Hematology , vol.17 , pp. 311-316
    • Pei, R.1    Cao, J.2    Ma, J.3
  • 34
    • 6944247414 scopus 로고    scopus 로고
    • An efficient therapeutic approach to patients with acute promyelocytic leukemia using a combination of arsenic trioxide with low-dose all-trans retinoic acid
    • Wang G, Li W, Cui J, et al. An efficient therapeutic approach to patients with acute promyelocytic leukemia using a combination of arsenic trioxide with low-dose all-trans retinoic acid. Hematol Oncol 2004; 22:63-71.
    • (2004) Hematol Oncol , vol.22 , pp. 63-71
    • Wang, G.1    Li, W.2    Cui, J.3
  • 35
    • 84855231183 scopus 로고    scopus 로고
    • Treatment advances have not improved the early death rate in acute promyelocytic leukemia
    • McClellan JS, Kohrt HE, Coutre S, et al. Treatment advances have not improved the early death rate in acute promyelocytic leukemia. Haematologica 2012; 97:133-136.
    • (2012) Haematologica , vol.97 , pp. 133-136
    • McClellan, J.S.1    Kohrt, H.E.2    Coutre, S.3
  • 36
    • 36348961330 scopus 로고    scopus 로고
    • Clinical features and outcomes of 134 Brazilians with acute promyelocytic leukemia who received ATRA and anthracyclines
    • Jacomo RH, Melo RAM, Souto FR, et al. Clinical features and outcomes of 134 Brazilians with acute promyelocytic leukemia who received ATRA and anthracyclines. Haematologica 2007; 92:1431-1432.
    • (2007) Haematologica , vol.92 , pp. 1431-1432
    • Jacomo, R.H.1    Melo, R.A.M.2    Souto, F.R.3
  • 37
    • 84862304906 scopus 로고    scopus 로고
    • Combination therapy with arsenic trioxide, alltrans retinoic acid, and chemotherapy in acute promyelocytic leukemia patients with various relapse risks
    • Huang H, Qin Y, Xu R, et al. Combination therapy with arsenic trioxide, alltrans retinoic acid, and chemotherapy in acute promyelocytic leukemia patients with various relapse risks. Leuk Res 2012; 36:841-845.
    • (2012) Leuk Res , vol.36 , pp. 841-845
    • Huang, H.1    Qin, Y.2    Xu, R.3
  • 38
    • 84870941699 scopus 로고    scopus 로고
    • High efficacy of arsenic trioxide plus all-trans retinoic acid based induction and maintenance therapy in newly diagnosed acute promyelocytic leukemia
    • Lou Y, Qian W, Meng H, et al. High efficacy of arsenic trioxide plus all-trans retinoic acid based induction and maintenance therapy in newly diagnosed acute promyelocytic leukemia. Leuk Res 2013; 37:37-42.
    • (2013) Leuk Res , vol.37 , pp. 37-42
    • Lou, Y.1    Qian, W.2    Meng, H.3
  • 39
    • 84872290502 scopus 로고    scopus 로고
    • Outcome of elderly patients with acute promyelocytic leukemia: Results of the German Acute Myeloid Leukemia Cooperative Group
    • Lengfelder E, Hanfstein B, Haferlach C, et al. Outcome of elderly patients with acute promyelocytic leukemia: results of the German Acute Myeloid Leukemia Cooperative Group. Ann Hematol 2013; 92:41-52.
    • (2013) Ann Hematol , vol.92 , pp. 41-52
    • Lengfelder, E.1    Hanfstein, B.2    Haferlach, C.3
  • 40
    • 79961092821 scopus 로고    scopus 로고
    • Early death rate in acute promyelocytic leukemia remains high despite all-trans retinoic acid
    • Park JH, Qiao B, Panageas KS, et al. Early death rate in acute promyelocytic leukemia remains high despite all-trans retinoic acid. Blood 2011; 118: 1248-1254.
    • (2011) Blood , vol.118 , pp. 1248-1254
    • Park, J.H.1    Qiao, B.2    Panageas, K.S.3
  • 41
    • 43549105926 scopus 로고    scopus 로고
    • Causes and prognostic factors of remission induction failure in patients with acute promyelocytic leukemia treated with all-trans retinoic acid and idarubicin
    • de la Serna J, Montesinos P, Vellenga E, et al. Causes and prognostic factors of remission induction failure in patients with acute promyelocytic leukemia treated with all-trans retinoic acid and idarubicin. Blood 2008; 111:3395-3402.
    • (2008) Blood , vol.111 , pp. 3395-3402
    • De La Serna, J.1    Montesinos, P.2    Vellenga, E.3
  • 42
    • 84856501661 scopus 로고    scopus 로고
    • Results of the APML3 trial incorporating all-trans-retinoic acid and idarubicin in both induction and consolidation as initial therapy for patients with acute promyelocytic leukemia
    • Iland H, Bradstock K, Seymour J, et al. Results of the APML3 trial incorporating all-trans-retinoic acid and idarubicin in both induction and consolidation as initial therapy for patients with acute promyelocytic leukemia. Haematologica 2012; 97:227-234.
    • (2012) Haematologica , vol.97 , pp. 227-234
    • Iland, H.1    Bradstock, K.2    Seymour, J.3
  • 43
    • 0033564337 scopus 로고    scopus 로고
    • Presenting white blood cell count and kinetics of molecular remission predict prognosis in acute promyelocytic leukemia treated with all-trans retinoic acid: Result of the randomized MRC trial
    • Burnett AK, Grimwade D, Solomon E, et al. Presenting white blood cell count and kinetics of molecular remission predict prognosis in acute promyelocytic leukemia treated with all-trans retinoic acid: result of the randomized MRC trial. Blood 1999; 93:4131-4143.
    • (1999) Blood , vol.93 , pp. 4131-4143
    • Burnett, A.K.1    Grimwade, D.2    Solomon, E.3
  • 44
    • 0033566639 scopus 로고    scopus 로고
    • A randomized comparison of all transretinoic acid (ATRA) followed by chemotherapy and ATRA plus chemotherapy and the role of maintenance therapy in newly diagnosed acute promyelocytic leukemia
    • Fenaux P, Chastang C, Chevret S, et al. A randomized comparison of all transretinoic acid (ATRA) followed by chemotherapy and ATRA plus chemotherapy and the role of maintenance therapy in newly diagnosed acute promyelocytic leukemia. Blood 1999; 94:1192-1200.
    • (1999) Blood , vol.94 , pp. 1192-1200
    • Fenaux, P.1    Chastang, C.2    Chevret, S.3
  • 45
    • 83555165967 scopus 로고    scopus 로고
    • The pathogenesis and management of the coagulopathy of acute promyelocytic leukaemia
    • Breen KA, Grimwade D, Hunt BJ. The pathogenesis and management of the coagulopathy of acute promyelocytic leukaemia. Br J Haematol 2012; 156:24-36.
    • (2012) Br J Haematol , vol.156 , pp. 24-36
    • Breen, K.A.1    Grimwade, D.2    Hunt, B.J.3
  • 46
    • 73949097021 scopus 로고    scopus 로고
    • How i treat acute promyelocytic leukemia
    • Tallman MS, Altman JK. How I treat acute promyelocytic leukemia. Blood 2009; 114:5126-5135.
    • (2009) Blood , vol.114 , pp. 5126-5135
    • Tallman, M.S.1    Altman, J.K.2
  • 47
    • 0027484597 scopus 로고
    • New insights into the pathogenesis of coagulation dysfunction in acute promyelocytic leukemia
    • Tallman MS, Hakimian D, Kwaan HC, Rickles FR. New insights into the pathogenesis of coagulation dysfunction in acute promyelocytic leukemia. Leuk Lymphoma 1993; 11:27-36.
    • (1993) Leuk Lymphoma , vol.11 , pp. 27-36
    • Tallman, M.S.1    Hakimian, D.2    Kwaan, H.C.3    Rickles, F.R.4
  • 48
    • 84866312450 scopus 로고    scopus 로고
    • Recombinant human soluble thrombomodulin safely and effectively rescues acute promyelocytic leukemia patients from disseminated intravascular coagulation
    • Ikezoe T, Takeuchi A, Isaka M, et al. Recombinant human soluble thrombomodulin safely and effectively rescues acute promyelocytic leukemia patients from disseminated intravascular coagulation. Leuk Res 2012; 36:1398-1402.
    • (2012) Leuk Res , vol.36 , pp. 1398-1402
    • Ikezoe, T.1    Takeuchi, A.2    Isaka, M.3
  • 49
    • 84863582642 scopus 로고    scopus 로고
    • Methionine-induced hyperhomocysteinemia reverts fibrinolytic pathway activation in a murine model of acute promyelocytic leukemia
    • Jacomo RH, Santana-Lemos BA, Lima ASG, et al. Methionine-induced hyperhomocysteinemia reverts fibrinolytic pathway activation in a murine model of acute promyelocytic leukemia. Blood 2012; 120:207-213.
    • (2012) Blood , vol.120 , pp. 207-213
    • Jacomo, R.H.1    Santana-Lemos, B.A.2    Lima, A.S.G.3
  • 50
    • 36248987130 scopus 로고    scopus 로고
    • Intracoronary thrombus with tissue factor expression heralding acute promyelocytic leukaemia
    • Altwegg SC, Altwegg LA,Maier W. Intracoronary thrombus with tissue factor expression heralding acute promyelocytic leukaemia. Eur Heart J 2007; 28:2731.
    • (2007) Eur Heart J , vol.28 , pp. 2731
    • Altwegg, S.C.1    Altwegg Lamaier, W.2
  • 51
    • 79953049854 scopus 로고    scopus 로고
    • Myocardial infarction with intracardiac thrombosis as the presentation of acute promyelocytic leukemia: Diagnosis and follow-up by cardiac magnetic resonance imaging
    • Cahill TJ, Chowdhury O, Myerson SG, et al. Myocardial infarction with intracardiac thrombosis as the presentation of acute promyelocytic leukemia: diagnosis and follow-up by cardiac magnetic resonance imaging. Circulation 2011; 123:e370-e372.
    • (2011) Circulation , vol.123
    • Cahill, T.J.1    Chowdhury, O.2    Myerson, S.G.3
  • 52
    • 84864108642 scopus 로고    scopus 로고
    • Acute promyelocytic leukemia as a cause of intracoronary drug-eluting-stent thrombosis
    • Sargsyan Z, Higgins C, Alexandrescu S, et al. Acute promyelocytic leukemia as a cause of intracoronary drug-eluting-stent thrombosis. Tex Heart Inst J 2012; 39:416-419.
    • (2012) Tex Heart Inst J , vol.39 , pp. 416-419
    • Sargsyan, Z.1    Higgins, C.2    Alexandrescu, S.3
  • 53
    • 9444297295 scopus 로고    scopus 로고
    • All-trans retinoic acid and anthracycline monochemotherapy for the treatment of elderly patients with acute promyelocytic leukemia
    • Sanz MA, Vellenga E, Rayon C, et al. All-trans retinoic acid and anthracycline monochemotherapy for the treatment of elderly patients with acute promyelocytic leukemia. Blood 2004; 104:3490-3493.
    • (2004) Blood , vol.104 , pp. 3490-3493
    • Sanz, M.A.1    Vellenga, E.2    Rayon, C.3
  • 54
    • 84855589943 scopus 로고    scopus 로고
    • A functional variant in the core promoter of the CD95 cell death receptor gene predicts prognosis in acute promyelocytic leukemia
    • Sunter NJ, Scott K, Hills R, et al. A functional variant in the core promoter of the CD95 cell death receptor gene predicts prognosis in acute promyelocytic leukemia. Blood 2012; 119:196-205.
    • (2012) Blood , vol.119 , pp. 196-205
    • Sunter, N.J.1    Scott, K.2    Hills, R.3
  • 55
    • 0026647140 scopus 로고
    • The 'retinoic acid syndrome' in acute promyelocytic leukemia
    • Frankel SR, Eardley A, Lauwers G, et al. The 'retinoic acid syndrome' in acute promyelocytic leukemia. Ann Intern Med 1992; 117:292-296.
    • (1992) Ann Intern Med , vol.117 , pp. 292-296
    • Frankel, S.R.1    Eardley, A.2    Lauwers, G.3
  • 56
    • 0033916673 scopus 로고    scopus 로고
    • Leukocytosis and the retinoic acid syndrome in patients with acute promyelocytic leukemia treated with arsenic trioxide
    • Camacho LH, Soignet SL, Chanel S, et al. Leukocytosis and the retinoic acid syndrome in patients with acute promyelocytic leukemia treated with arsenic trioxide. J Clin Oncol 2000; 18:2620-2625.
    • (2000) J Clin Oncol , vol.18 , pp. 2620-2625
    • Camacho, L.H.1    Soignet, S.L.2    Chanel, S.3
  • 57
    • 59649106888 scopus 로고    scopus 로고
    • Differentiation syndrome in patients with acute promyelocytic leukemia treated with all-trans retinoic acid and anthracycline chemotherapy: Characteristics, outcome, and prognostic factors
    • Montesinos P, Bergua JM, Vellenga E, et al. Differentiation syndrome in patients with acute promyelocytic leukemia treated with all-trans retinoic acid and anthracycline chemotherapy: characteristics, outcome, and prognostic factors. Blood 2009; 113:775-783.
    • (2009) Blood , vol.113 , pp. 775-783
    • Montesinos, P.1    Bergua, J.M.2    Vellenga, E.3
  • 58
    • 84855577993 scopus 로고    scopus 로고
    • Increased BMI correlates with higher risk of disease relapse and differentiation syndrome in patients with acute promyelocytic leukemia treated with the AIDA protocols
    • Breccia M, Mazzarella L, Bagnardi V, et al. Increased BMI correlates with higher risk of disease relapse and differentiation syndrome in patients with acute promyelocytic leukemia treated with the AIDA protocols. Blood 2012; 119:49-54.
    • (2012) Blood , vol.119 , pp. 49-54
    • Breccia, M.1    Mazzarella, L.2    Bagnardi, V.3
  • 59
    • 84868095230 scopus 로고    scopus 로고
    • Long-term outcome and prognostic factors of elderly patients with acute promyelocytic leukemia
    • Ono T, Takeshita A, Kishimoto Y, et al. Long-term outcome and prognostic factors of elderly patients with acute promyelocytic leukemia. Cancer Sci 2012; 103:1974-1978.
    • (2012) Cancer Sci , vol.103 , pp. 1974-1978
    • Ono, T.1    Takeshita, A.2    Kishimoto, Y.3
  • 60
    • 79955991053 scopus 로고    scopus 로고
    • AIDA 0493 protocol for newly diagnosed acute promyelocytic leukemia: Very long-term results and role of maintenance
    • Avvisati G, Lo-Coco F, Paoloni FP, et al. AIDA 0493 protocol for newly diagnosed acute promyelocytic leukemia: very long-term results and role of maintenance. Blood 2011; 117:4716-4725.
    • (2011) Blood , vol.117 , pp. 4716-4725
    • Avvisati, G.1    Lo-Coco, F.2    Paoloni, F.P.3
  • 61
    • 84880287051 scopus 로고    scopus 로고
    • Retinoic acid and arsenic trioxide for acute promyelocytic leukemia
    • Lo-Coco F, Avvisati G, Vignetti M, et al. Retinoic acid and arsenic trioxide for acute promyelocytic leukemia. N Engl J Med 2013; 369:111-121.
    • (2013) N Engl J Med , vol.369 , pp. 111-121
    • Lo-Coco, F.1    Avvisati, G.2    Vignetti, M.3
  • 62
    • 84869502214 scopus 로고    scopus 로고
    • Acute promyelocytic leukemia: A population-based study on incidence and survival in the United States, 1975-2008
    • Chen Y, Kantarjian H, Wang H, et al. Acute promyelocytic leukemia: a population-based study on incidence and survival in the United States, 1975-2008. Cancer 2012; 118:5811-5818.
    • (2012) Cancer , vol.118 , pp. 5811-5818
    • Chen, Y.1    Kantarjian, H.2    Wang, H.3
  • 63
    • 0034663162 scopus 로고    scopus 로고
    • Definition of relapse risk and role of nonanthracycline drugs for consolidation in patients with acute promyelocytic leukemia: A joint study of the PETHEMA and GIMEMA cooperative groups
    • Sanz MA, Coco FL, Martin G, et al. Definition of relapse risk and role of nonanthracycline drugs for consolidation in patients with acute promyelocytic leukemia: a joint study of the PETHEMA and GIMEMA cooperative groups. Blood 2000; 96:1247-1253.
    • (2000) Blood , vol.96 , pp. 1247-1253
    • Sanz, M.A.1    Coco, F.L.2    Martin, G.3
  • 64
    • 70349124202 scopus 로고    scopus 로고
    • Central nervous system involvement at first relapse in patients with acute promyelocytic leukemia treated with all-trans retinoic acid and anthracycline monochemotherapy without intrathecal prophylaxis
    • Montesinos P, Diaz-Mediavilla J, Deben G, et al. Central nervous system involvement at first relapse in patients with acute promyelocytic leukemia treated with all-trans retinoic acid and anthracycline monochemotherapy without intrathecal prophylaxis. Haematologica 2009; 94:1242-1249.
    • (2009) Haematologica , vol.94 , pp. 1242-1249
    • Montesinos, P.1    Diaz-Mediavilla, J.2    Deben, G.3
  • 65
    • 0034061846 scopus 로고    scopus 로고
    • CD56 expression is an indicator of poor clinical outcome in patients with acute promyelocytic leukemia treated with simultaneous all-trans-retinoic acid and chemotherapy
    • Ferrara F, Morabito F, Martino B, et al. CD56 expression is an indicator of poor clinical outcome in patients with acute promyelocytic leukemia treated with simultaneous all-trans-retinoic acid and chemotherapy. J Clin Oncol 2000; 18:1295-1300.
    • (2000) J Clin Oncol , vol.18 , pp. 1295-1300
    • Ferrara, F.1    Morabito, F.2    Martino, B.3
  • 66
    • 79951503141 scopus 로고    scopus 로고
    • Clinical significance of CD56 expression in patients with acute promyelocytic leukemia treated with alltrans retinoic acid and anthracycline-based regimens
    • Montesinos P, Rayon C, Vellenga E, et al. Clinical significance of CD56 expression in patients with acute promyelocytic leukemia treated with alltrans retinoic acid and anthracycline-based regimens. Blood 2011; 117:1799-1805.
    • (2011) Blood , vol.117 , pp. 1799-1805
    • Montesinos, P.1    Rayon, C.2    Vellenga, E.3
  • 67
    • 0036850573 scopus 로고    scopus 로고
    • Alterations of the FLT3 gene in acute promyelocytic leukemia: Association with diagnostic characteristics and analysis of clinical outcome in patients treated with the Italian AIDA protocol
    • Noguera NI, Breccia M, Divona M, et al. Alterations of the FLT3 gene in acute promyelocytic leukemia: association with diagnostic characteristics and analysis of clinical outcome in patients treated with the Italian AIDA protocol. Leukemia 2002; 16:2185-2189.
    • (2002) Leukemia , vol.16 , pp. 2185-2189
    • Noguera, N.I.1    Breccia, M.2    Divona, M.3
  • 68
    • 28444485658 scopus 로고    scopus 로고
    • Relationship between FLT3 mutation status, biologic characteristics, and response to targeted therapy in acute promyelocytic leukemia
    • Gale RE, Hills R, Pizzey AR, et al. Relationship between FLT3 mutation status, biologic characteristics, and response to targeted therapy in acute promyelocytic leukemia. Blood 2005; 106:3768-3776.
    • (2005) Blood , vol.106 , pp. 3768-3776
    • Gale, R.E.1    Hills, R.2    Pizzey, A.R.3
  • 69
    • 24944447981 scopus 로고    scopus 로고
    • Impact of FLT3 mutations and promyelocytic leukaemia-breakpoint on clinical characteristics and prognosis in acute promyelocytic leukaemia
    • Kuchenbauer F, Schoch C, Kern W, et al. Impact of FLT3 mutations and promyelocytic leukaemia-breakpoint on clinical characteristics and prognosis in acute promyelocytic leukaemia. Br J Haematol 2005; 130:196-202.
    • (2005) Br J Haematol , vol.130 , pp. 196-202
    • Kuchenbauer, F.1    Schoch, C.2    Kern, W.3
  • 70
    • 33750485843 scopus 로고    scopus 로고
    • Inferior prognostic outcome in acute promyelocytic leukemia with alterations of FLT3 gene
    • Yoo SJ, Park CJ, Jang S, et al. Inferior prognostic outcome in acute promyelocytic leukemia with alterations of FLT3 gene. Leuk Lymphoma 2006; 47:1788-1793.
    • (2006) Leuk Lymphoma , vol.47 , pp. 1788-1793
    • Yoo, S.J.1    Park, C.J.2    Jang, S.3
  • 71
    • 34548770012 scopus 로고    scopus 로고
    • Impact of FLT3 mutations and secondary cytogenetic changes on the outcome of patients with newly diagnosed acute promyelocytic leukemia treated with a single agent arsenic trioxide regimen
    • Mathews V, Thomas M, Srivastava VM, et al. Impact of FLT3 mutations and secondary cytogenetic changes on the outcome of patients with newly diagnosed acute promyelocytic leukemia treated with a single agent arsenic trioxide regimen. Haematologica 2007; 92:994-995.
    • (2007) Haematologica , vol.92 , pp. 994-995
    • Mathews, V.1    Thomas, M.2    Srivastava, V.M.3
  • 72
    • 77952954175 scopus 로고    scopus 로고
    • Prognostic significance of FLT3 internal tandem duplication and tyrosine kinase domain mutations in acute promyelocytic leukemia: A systematic review
    • Beitinjaneh A, Jang S, Roukoz H, Majhail NS. Prognostic significance of FLT3 internal tandem duplication and tyrosine kinase domain mutations in acute promyelocytic leukemia: a systematic review. Leuk Res 2010; 34:831-836.
    • (2010) Leuk Res , vol.34 , pp. 831-836
    • Beitinjaneh, A.1    Jang, S.2    Roukoz, H.3    Majhail, N.S.4
  • 73
    • 77952304009 scopus 로고    scopus 로고
    • Long FLT3 internal tandem duplications and reduced PML-RAR expression at diagnosis characterize a high-risk subgroup of acute promyelocytic leukemia patients
    • Chillon MC, Santamaria C, Garcia-Sanz R, et al. Long FLT3 internal tandem duplications and reduced PML-RAR expression at diagnosis characterize a high-risk subgroup of acute promyelocytic leukemia patients. Haematologica 2010; 95:745-751.
    • (2010) Haematologica , vol.95 , pp. 745-751
    • Chillon, M.C.1    Santamaria, C.2    Garcia-Sanz, R.3
  • 74
    • 80054008816 scopus 로고    scopus 로고
    • Prognostic value of FLT3 mutations in patients with acute promyelocytic leukemia treated with alltrans retinoic acid and anthracycline monochemotherapy
    • Barragan E, Montesinos P, Camos M, et al. Prognostic value of FLT3 mutations in patients with acute promyelocytic leukemia treated with alltrans retinoic acid and anthracycline monochemotherapy. Haematologica 2011; 96:1470-1477.
    • (2011) Haematologica , vol.96 , pp. 1470-1477
    • Barragan, E.1    Montesinos, P.2    Camos, M.3
  • 75
    • 82855164008 scopus 로고    scopus 로고
    • Clinical impact of FLT3 mutation load in acute promyelocytic leukemia with t(15;17)/PML-RARA
    • Schnittger S, Bacher U, Haferlach C, et al. Clinical impact of FLT3 mutation load in acute promyelocytic leukemia with t(15;17)/PML-RARA. Haematologica 2011; 96:1799-1807.
    • (2011) Haematologica , vol.96 , pp. 1799-1807
    • Schnittger, S.1    Bacher, U.2    Haferlach, C.3
  • 76
    • 84864945751 scopus 로고    scopus 로고
    • FLT3 mutation status is a predictor of early death in pediatric acute promyelocytic leukemia: A report from the Children's Oncology Group
    • Kutny MA, Moser BK, Laumann K, et al. FLT3 mutation status is a predictor of early death in pediatric acute promyelocytic leukemia: a report from the Children's Oncology Group. Pediatr Blood Cancer 2012; 59:662-667.
    • (2012) Pediatr Blood Cancer , vol.59 , pp. 662-667
    • Kutny, M.A.1    Moser, B.K.2    Laumann, K.3
  • 77
    • 84872820174 scopus 로고    scopus 로고
    • Prognostic implications of additional chromosome abnormalities among patients with de novo acute promyelocytic leukemia with t(15;17)
    • Wiernik PH, Sun Z, Gundacker H, et al. Prognostic implications of additional chromosome abnormalities among patients with de novo acute promyelocytic leukemia with t(15;17). Med Oncol 2012; 29:2095-2101.
    • (2012) Med Oncol , vol.29 , pp. 2095-2101
    • Wiernik, P.H.1    Sun, Z.2    Gundacker, H.3
  • 78
    • 84877050094 scopus 로고    scopus 로고
    • High expression of the Ets-related gene (ERG) is an independent prognostic marker for relapse-free survival in patients with acute promyelocytic leukemia
    • Hecht A, Nowak D, Nowak V, et al. High expression of the Ets-related gene (ERG) is an independent prognostic marker for relapse-free survival in patients with acute promyelocytic leukemia. Ann Hematol 2013; 92:443-449.
    • (2013) Ann Hematol , vol.92 , pp. 443-449
    • Hecht, A.1    Nowak, D.2    Nowak, V.3
  • 79
    • 84875381732 scopus 로고    scopus 로고
    • In acute promyelocytic leukemia (APL) low BAALC gene expression identifies a patient group with favorable overall survival and improved relapse free survival
    • Nolte F, Hecht A, Reinwald M, et al. In acute promyelocytic leukemia (APL) low BAALC gene expression identifies a patient group with favorable overall survival and improved relapse free survival. Leuk Res 2013; 37:378-382.
    • (2013) Leuk Res , vol.37 , pp. 378-382
    • Nolte, F.1    Hecht, A.2    Reinwald, M.3
  • 80
    • 84861717511 scopus 로고    scopus 로고
    • SNP array analysis of acute promyelocytic leukemia may be of prognostic relevance and identifies a potential high risk group with recurrent deletions on chromosomal subband 1q31.3
    • Nowak D, Klaumuenzer M, Hanfstein B, et al. SNP array analysis of acute promyelocytic leukemia may be of prognostic relevance and identifies a potential high risk group with recurrent deletions on chromosomal subband 1q31.3. Genes Chromosomes Cancer 2012; 51:756-767.
    • (2012) Genes Chromosomes Cancer , vol.51 , pp. 756-767
    • Nowak, D.1    Klaumuenzer, M.2    Hanfstein, B.3
  • 81
    • 84875381625 scopus 로고    scopus 로고
    • Influence of time to complete remission and duration of all-trans retinoic acid therapy on the relapse risk in patients with acute promyelocytic leukemia receiving AIDA protocols
    • Breccia M, Minotti C, Latagliata R, et al. Influence of time to complete remission and duration of all-trans retinoic acid therapy on the relapse risk in patients with acute promyelocytic leukemia receiving AIDA protocols. Leuk Res 2013; 37:383-385.
    • (2013) Leuk Res , vol.37 , pp. 383-385
    • Breccia, M.1    Minotti, C.2    Latagliata, R.3
  • 82
    • 84862882135 scopus 로고    scopus 로고
    • Quantification of PML/RARa transcript after induction predicts outcome in children with acute promyelocytic leukemia
    • Zhang L, Cao Z, Zou Y, et al. Quantification of PML/RARa transcript after induction predicts outcome in children with acute promyelocytic leukemia. Int J Hematol 2012; 95:500-508.
    • (2012) Int J Hematol , vol.95 , pp. 500-508
    • Zhang, L.1    Cao, Z.2    Zou, Y.3
  • 83
    • 0038378897 scopus 로고    scopus 로고
    • Treatment of elderly patients (> or=60 years) with newly diagnosed acute promyelocytic leukemia. Results of the Italian multicenter group GIMEMA with ATRA and idarubicin (AIDA) protocols
    • Mandelli F, Latagliata R, Avvisati G, et al. Treatment of elderly patients (> or=60 years) with newly diagnosed acute promyelocytic leukemia. Results of the Italian multicenter group GIMEMA with ATRA and idarubicin (AIDA) protocols. Leukemia 2003; 17:1085-1090.
    • (2003) Leukemia , vol.17 , pp. 1085-1090
    • Mandelli, F.1    Latagliata, R.2    Avvisati, G.3
  • 84
    • 54049087434 scopus 로고    scopus 로고
    • Risk-adapted treatment of acute promyelocytic leukemia with all-trans retinoic acid and anthracycline monochemotherapy: Long-term outcome of the LPA 99 multicenter study by the PETHEMA Group
    • Sanz MA, Montesinos P, Vellenga E, et al. Risk-adapted treatment of acute promyelocytic leukemia with all-trans retinoic acid and anthracycline monochemotherapy: long-term outcome of the LPA 99 multicenter study by the PETHEMA Group. Blood 2008; 112:3130-3134.
    • (2008) Blood , vol.112 , pp. 3130-3134
    • Sanz, M.A.1    Montesinos, P.2    Vellenga, E.3
  • 85
    • 84876120195 scopus 로고    scopus 로고
    • Inclusion of chemotherapy in addition to anthracycline in the treatment of acute promyelocytic leukaemia does not improve outcomes: Results of the MRC AML15 trial
    • Burnett AK, Hills RK, Grimwade D, et al. Inclusion of chemotherapy in addition to anthracycline in the treatment of acute promyelocytic leukaemia does not improve outcomes: results of the MRC AML15 trial. Leukemia 2013; 27:843-851.
    • (2013) Leukemia , vol.27 , pp. 843-851
    • Burnett, A.K.1    Hills, R.K.2    Grimwade, D.3
  • 86
    • 0033890197 scopus 로고    scopus 로고
    • Long-term follow-up confirms the benefit of all-trans retinoic acid in acute promyelocytic leukemia
    • Fenaux P, Chevret S, Guerci A, et al. Long-term follow-up confirms the benefit of all-trans retinoic acid in acute promyelocytic leukemia. European APL group. Leukemia 2000; 14:1371-1377.
    • (2000) European APL Group. Leukemia , vol.14 , pp. 1371-1377
    • Fenaux, P.1    Chevret, S.2    Guerci, A.3
  • 87
    • 0037115195 scopus 로고    scopus 로고
    • All-trans retinoic acid in acute promyelocytic leukemia: Long-term outcome and prognostic factor analysis from the North American Intergroup protocol
    • Tallman MS, Andersen JW, Schiffer CA, et al. All-trans retinoic acid in acute promyelocytic leukemia: long-term outcome and prognostic factor analysis from the North American Intergroup protocol. Blood 2002; 100:4298-4302.
    • (2002) Blood , vol.100 , pp. 4298-4302
    • Tallman, M.S.1    Andersen, J.W.2    Schiffer, C.A.3
  • 88
    • 11144355810 scopus 로고    scopus 로고
    • All-trans retinoic acid/As2O3 combination yields a high quality remission and survival in newly diagnosed acute promyelocytic leukemia
    • Shen Z-X, Shi Z-Z, Fang J, et al. All-trans retinoic acid/As2O3 combination yields a high quality remission and survival in newly diagnosed acute promyelocytic leukemia. Proc Natl Acad Sci U S A 2004; 101:5328-5335.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 5328-5335
    • Shen, Z.-X.1    Shi, Z.-Z.2    Fang, J.3
  • 89
    • 66849103735 scopus 로고    scopus 로고
    • Improved outcome of acute promyelocytic leukemia with high WBC counts over the last 15 years: The European APL Group Experience
    • Kelaidi C, Chevret S, De Botton S, et al. Improved outcome of acute promyelocytic leukemia with high WBC counts over the last 15 years: The European APL Group Experience. J Clin Oncol 2009; 27:2668-2676.
    • (2009) J Clin Oncol , vol.27 , pp. 2668-2676
    • Kelaidi, C.1    Chevret, S.2    De Botton, S.3
  • 90
    • 84877782065 scopus 로고    scopus 로고
    • Role of arsenic trioxide in acute promyelocytic leukemia
    • Iland H, Seymour J. Role of arsenic trioxide in acute promyelocytic leukemia. Curr Treat Options Oncol 2013; 14:170-184.
    • (2013) Curr Treat Options Oncol , vol.14 , pp. 170-184
    • Iland, H.1    Seymour, J.2
  • 91
    • 84864042079 scopus 로고    scopus 로고
    • Subclinical anthracycline cardiotoxicity in patients with acute promyelocytic leukemia in long-term remission after the AIDA protocol
    • Pellicori P, Calicchia A, Lococo F, et al. Subclinical anthracycline cardiotoxicity in patients with acute promyelocytic leukemia in long-term remission after the AIDA protocol. Congest Heart Fail 2012; 18:217-221.
    • (2012) Congest Heart Fail , vol.18 , pp. 217-221
    • Pellicori, P.1    Calicchia, A.2    Lococo, F.3
  • 92
    • 0029942879 scopus 로고    scopus 로고
    • Accelerated degradation of PMLretinoic acid receptor alpha (PML-RARA) oncoprotein by all-trans-retinoic acid in acute promyelocytic leukemia: Possible role of the proteasome pathway
    • Yoshida H, Kitamura K, Tanaka K, et al. Accelerated degradation of PMLretinoic acid receptor alpha (PML-RARA) oncoprotein by all-trans-retinoic acid in acute promyelocytic leukemia: possible role of the proteasome pathway. Cancer Res 1996; 56:2945-2948.
    • (1996) Cancer Res , vol.56 , pp. 2945-2948
    • Yoshida, H.1    Kitamura, K.2    Tanaka, K.3
  • 94
    • 0032753459 scopus 로고    scopus 로고
    • Missense mutations in the PML/ RARalpha ligand binding domain in ATRA-resistant As(2)O(3) sensitive relapsed acute promyelocytic leukemia
    • Marasca R, Zucchini P, Galimberti S, et al. Missense mutations in the PML/ RARalpha ligand binding domain in ATRA-resistant As(2)O(3) sensitive relapsed acute promyelocytic leukemia. Haematologica 1999; 84:963-968.
    • (1999) Haematologica , vol.84 , pp. 963-968
    • Marasca, R.1    Zucchini, P.2    Galimberti, S.3
  • 95
    • 84866156989 scopus 로고    scopus 로고
    • Treatment-influenced associations of PML-RAR mutations, FLT3 mutations, and additional chromosome abnormalities in relapsed acute promyelocytic leukemia
    • Gallagher RE, Moser BK, Racevskis J, et al. Treatment-influenced associations of PML-RAR mutations, FLT3 mutations, and additional chromosome abnormalities in relapsed acute promyelocytic leukemia. Blood 2012; 120:2098-2108.
    • (2012) Blood , vol.120 , pp. 2098-2108
    • Gallagher, R.E.1    Moser, B.K.2    Racevskis, J.3
  • 96
    • 33646386643 scopus 로고    scopus 로고
    • Use of all-trans retinoic acid plus arsenic trioxide as an alternative to chemotherapy in untreated acute promyelocytic leukemia
    • Estey E, Garcia-Manero G, Ferrajoli A, et al. Use of all-trans retinoic acid plus arsenic trioxide as an alternative to chemotherapy in untreated acute promyelocytic leukemia. Blood 2006; 107:3469-3473.
    • (2006) Blood , vol.107 , pp. 3469-3473
    • Estey, E.1    Garcia-Manero, G.2    Ferrajoli, A.3
  • 97
    • 77950361899 scopus 로고    scopus 로고
    • Very long-term outcome of acute promyelocytic leukemia after treatment with all-trans retinoic acid and chemotherapy: The European APL Group experience
    • Ades L, Guerci A, Raffoux E, et al. Very long-term outcome of acute promyelocytic leukemia after treatment with all-trans retinoic acid and chemotherapy: the European APL Group experience. Blood 2010; 115:1690-1696.
    • (2010) Blood , vol.115 , pp. 1690-1696
    • Ades, L.1    Guerci, A.2    Raffoux, E.3
  • 98
    • 84880057409 scopus 로고    scopus 로고
    • The role of maintenance therapy in acute promyelocytic leukemia in the first complete remission
    • Muchtar E, Vidal L, Ram R, et al. The role of maintenance therapy in acute promyelocytic leukemia in the first complete remission. Cochrane Database Syst Rev 2013; 3:CD009594.
    • (2013) Cochrane Database Syst Rev , vol.3
    • Muchtar, E.1    Vidal, L.2    Ram, R.3
  • 99
    • 84055213176 scopus 로고    scopus 로고
    • Oral arsenic trioxide-based maintenance regimens for first complete remission of acute promyelocytic leukemia: A 10-year follow-up study
    • Au W-Y, Kumana CR, Lee HKK, et al. Oral arsenic trioxide-based maintenance regimens for first complete remission of acute promyelocytic leukemia: a 10-year follow-up study. Blood 2011; 118:6535-6543.
    • (2011) Blood , vol.118 , pp. 6535-6543
    • Au, W.-Y.1    Kumana, C.R.2    Lee, H.K.K.3
  • 100
    • 84892940228 scopus 로고    scopus 로고
    • Oral tetra-arsenic tetra-sulfide formula versus intravenous arsenic trioxide as first-line treatment of acute promyelocytic leukemia: A multicenter randomized controlled trial
    • Zhu Z-H, Wu D-P, Jin J, et al. Oral tetra-arsenic tetra-sulfide formula versus intravenous arsenic trioxide as first-line treatment of acute promyelocytic leukemia: a multicenter randomized controlled trial. J Clin Oncol 2013; 31:4215-4221.
    • (2013) J Clin Oncol , vol.31 , pp. 4215-4221
    • Zhu, Z.-H.1    Wu, D.-P.2    Jin, J.3


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