The detection of intraoperative bacterial translocation in the mesenteric lymph nodes is useful in predicting patients at high risk for postoperative infectious complications after esophagectomy

Annals of Surgery

Volumn 259, Issue 3, 2014, Pages 477-484

  Nishigaki, Eiji ^a   Abe, Tetsuya ^a   Yokoyama, Yukihiro ^a   Fukaya, Masahide ^a   Asahara, Takashi ^b   Nomoto, Koji ^b   Nagino, Masato ^a  

^a NAGOYA UNIVERSITY   (Japan)

^b YAKULT CENTRAL INSTITUTE FOR MICROBIOLOGICAL RESEARCH   (Japan)

Author keywords

bacteremia; bacterium specific ribosomal RNA; mesenteric lymph nodes

Indexed keywords

AGED, 80 AND OVER; BACTERIA; BACTERIAL TRANSLOCATION; ESOPHAGEAL NEOPLASMS; ESOPHAGECTOMY; FEMALE; FOLLOW-UP STUDIES; HUMANS; INCIDENCE; JAPAN; LENGTH OF STAY; LYMPH NODES; MALE; MESENTERY; PROGNOSIS; RETROSPECTIVE STUDIES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RISK FACTORS; RNA, BACTERIAL; SURGICAL WOUND INFECTION;

EID: 84894059541     PISSN: 00034932     EISSN: 15281140     Source Type: Journal    
DOI: 10.1097/SLA.0b013e31828e39e8     Document Type: Article

References (19)

1. Sato N, Koeda K, Ikeda K, et al. Randomized study of the benefits of preoperative corticosteroid administration on the postoperative morbidity and cytokine response in patients undergoing surgery for esophageal cancer. Ann Surg. 2002;236:184-190. (Pubitemid 34809537)
2. Kooguchi K, Kobayashi A, Kitamura Y, et al. Elevated expression of inducible nitric oxide synthase and inflammatory cytokines in the alveolar macrophages after esophagectomy. Crit Care Med. 2002;30:71-76. (Pubitemid 34112179)
3. Igaki H, Tachimori Y, Kato H. Improved survival for patients with upper and/or middle mediastinal lymph node metastasis of squamous cell carcinoma of the lower thoracic esophagus treated with 3-field dissection. Ann Surg. 2004;239:483-490. (Pubitemid 38372764)
4. van Sandick JW, Gisbertz SS, ten Berge IJ, et al. Immune responses and prediction ofmajor infection in patients undergoing transhiatal or transthoracic esophagectomy for cancer. Ann Surg. 2003;237:35-43. (Pubitemid 36622315)
5. Shimizu K, Ogura H, Goto M, et al. Altered gut flora and environment in patients with severe SIRS. J Trauma. 2006;60:126-133.
6. Mizuno T, Yokoyama Y, Nishio H, et al. Intraoperative bacterial translocation detected by bacterium-specific ribosomal RNA-targeted reverse-transcriptase polymerase chain reaction for the mesenteric lymph node strongly predicts postoperative infectious complications after major hepatectomy for biliary malignancies. Ann Surg. 2010;252:1013-1019.
7. Matsuda K, Tsuji H, Asahara T, et al. Sensitive quantitative detection of commensal bacteria by rRNA-targeted reverse transcription-PCR. Appl Environ Microbiol. 2007;73:32-39. (Pubitemid 46079932)
8. Matsuda K, Tsuji H, Asahara T, et al. Establishment of an analytical system for the human fecal microbiota, based on reverse transcription- quantitative PCR targeting of multicopy rRNA molecules. Appl Environ Microbiol. 2009;75:1961-1969.
9. Sakaguchi S, Saito M, Tsuji H, et al. Bacterial rRNA-targeted reverse transcription-PCR used to identify pathogens responsible for fever with neutropenia. J Clin Microbiol. 2010;48:1624-1628.
10. Wada M, Lkhagvadorj E, Bian L, et al. Quantitative reverse transcription-PCR assay for the rapid detection of methicillin-resistant Staphylococcus aureus. J Appl Microbiol. 2010;108:779-788.
11. Mangram AJ, Horan TC, Pearson ML, et al. Guideline for prevention of surgical site infection, 1999. Centers for Disease Control and Prevention (CDC) hospital infection control practices advisory committee. Am J Infect Control. 1999;27:97-132; quiz 133-134; discussion 196.
12. Deitch EA. Nutrition and the gut mucosal barrier. Curr Opin Gen Surg. 1993:85-91.
13. Saadia R, ScheinM,MacFarlane C, et al. Gut barrier function and the surgeon. Br J Surg. 1990;77:487-492. (Pubitemid 20164685)
14. Stechmiller JK, Treloar D, Allen N. Gut dysfunction in critically ill patients: a review of the literature. Am J Crit Care. 1997;6:204-209. (Pubitemid 127457725)
15. MacFie J. Enteral versus parenteral nutrition: the significance of bacterial translocation and gut-barrier function. Nutrition. 2000;16:606-611. (Pubitemid 30445123)
16. Eckburg PB, Bik EM, Bernstein CN, et al. Diversity of the human intestinal microbial flora. Science. 2005;308:1635-1638. (Pubitemid 40807514)
17. O'Boyle CJ, MacFie J, Mitchell CJ, et al. Microbiology of bacterial translocation in humans. Gut. 1998;42:29-35. (Pubitemid 28228384)
18. MacFie J, Reddy BS, Gatt M, et al. Bacterial translocation studied in 927 patients over 13 years. Br J Surg. 2006;93:87-93. (Pubitemid 43117311)
19. Yeh DC, Wu CC, Ho WM, et al. Bacterial translocation after cirrhotic liver resection: a clinical investigation of 181 patients. J Surg Res. 2003;111: 209-214.