TAILOR: Transgene activation and inactivation using lox and rox in zebrafish

PLoS ONE

Volumn 8, Issue 12, 2013, Pages

  Park, Joon Tae ^a   Leach, Steven D ^a,b  

^a DEPARTMENT OF PATHOLOGY   (United States)

^b JOHNS HOPKINS UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMALS; ESCHERICHIA COLI PROTEINS; GENE EXPRESSION REGULATION; GENE TRANSFER TECHNIQUES; INTEGRASES; MICROSCOPY, CONFOCAL; MIFEPRISTONE; RECOMBINASES; SUBSTRATE SPECIFICITY; TRANSGENES; ZEBRAFISH;

EID: 84894045252     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0085218     Document Type: Article

References (37)

1. Mosimann C, Kaufman CK, Li P, Pugach EK, Tamplin OJ, et al. (2011) Ubiquitous transgene expression and Cre-based recombination driven by the ubiquitin promoter in zebrafish. Development 138: 169-177.
2. Sinha DK, Neveu P, Gagey N, Aujard I, Le Saux T, et al. (2010) Photoactivation of the CreER T2 recombinase for conditional site-specific recombination with high spatiotemporal resolution. Zebrafish 7: 199-204.
3. Collins RT, Linker C, Lewis J (2010) MAZe: a tool for mosaic analysis of gene function in zebrafish. Nat Methods 7: 219-223.
4. Seok SH, Na YR, Han JH, Kim TH, Jung H, et al. (2010) Cre/loxP-regulated transgenic zebrafish model for neural progenitor-specific oncogenic Kras expression. Cancer Sci 101: 149-154.
5. Speck NA, Iruela-Arispe ML (2009) Conditional Cre/LoxP strategies for the study of hematopoietic stem cell formation. Blood Cells Mol Dis 43: 6-11.
6. Le X, Langenau DM, Keefe MD, Kutok JL, Neuberg DS, et al. (2007) Heat shock-inducible Cre/Lox approaches to induce diverse types of tumors and hyperplasia in transgenic zebrafish. Proc Natl Acad Sci U S A 104: 9410-9415. (Pubitemid 47185793)
7. Liu WY, Wang Y, Qin Y, Wang YP, Zhu ZY (2007) Site-directed gene integration in transgenic zebrafish mediated by cre recombinase using a combination of mutant lox sites. Mar Biotechnol (NY) 9: 420-428. (Pubitemid 47492125)
8. Pan X, Wan H, Chia W, Tong Y, Gong Z (2005) Demonstration of site-directed recombination in transgenic zebrafish using the Cre/loxP system. Transgenic Res 14: 217-223. (Pubitemid 40747900)
9. Thummel R, Burket CT, Brewer JL, Sarras MP Jr, Li L, et al. (2005) Cremediated site-specific recombination in zebrafish embryos. Dev Dyn 233: 1366-1377. (Pubitemid 40995134)
10. Langenau DM, Feng H, Berghmans S, Kanki JP, Kutok JL, et al. (2005) Cre/lox-regulated transgenic zebrafish model with conditional myc-induced T cell acute lymphoblastic leukemia. Proc Natl Acad Sci U S A 102: 6068-6073. (Pubitemid 40594256)
11. Dong J, Stuart GW (2004) Transgene manipulation in zebrafish by using recombinases. Methods Cell Biol 77: 363-379.
12. Ni TT, Lu J, Zhu M, Maddison LA, Boyd KL, et al. (2012) Conditional control of gene function by an invertible gene trap in zebrafish. Proc Natl Acad Sci U S A 109: 15389-15394.
13. Trinh le A, Hochgreb T, Graham M, Wu D, Ruf-Zamojski F, et al. (2011) A versatile gene trap to visualize and interrogate the function of the vertebrate proteome. Genes Dev 25: 2306-2320.
14. Wong AC, Draper BW, Van Eenennaam AL (2011) FLPe functions in zebrafish embryos. Transgenic Res 20: 409-415.
15. Boniface EJ, Lu J, Victoroff T, Zhu M, Chen W (2009) FlEx-based transgenic reporter lines for visualization of Cre and Flp activity in live zebrafish. Genesis 47: 484-491.
16. Wang Y, Rovira M, Yusuff S, Parsons MJ (2011) Genetic inducible fate mapping in larval zebrafish reveals origins of adult insulin-producing beta-cells. Development 138: 609-617.
17. Sauer B, McDermott J (2004) DNA recombination with a heterospecific Cre homolog identified from comparison of the pac-c1 regions of P1-related phages. Nucleic Acids Research 32: 6086-6095. (Pubitemid 40074003)
18. Anastassiadis K, Fu J, Patsch C, Hu S, Weidlich S, et al. (2009) Dre recombinase, like Cre, is a highly efficient site-specific recombinase in E. coli, mammalian cells and mice. Dis Model Mech 2: 508-515.
19. Sauer B, McDermott J (2004) DNA recombination with a heterospecific Cre homolog identified from comparison of the pac-c1 regions of P1-related phages. Nucleic Acids Res 32: 6086-6095. (Pubitemid 40074003)
20. Mosimann C, Kaufman CK, Li P, Pugach EK, Tamplin OJ, et al. (2011) Ubiquitous transgene expression and Cre-based recombination driven by the ubiquitin promoter in zebrafish. Development 138: 169-177.
21. Kawakami K (2004) Transgenesis and gene trap methods in zebrafish by using the Tol2 transposable element. Methods Cell Biol 77: 201-222.
22. Parsons MJ, Pisharath H, Yusuff S, Moore JC, Siekmann AF, et al. (2009) Notch-responsive cells initiate the secondary transition in larval zebrafish pancreas. Mech Dev 126: 898-912.
23. Hesselson D, Anderson RM, Stainier DY (2011) Suppression of Ptf1a activity induces acinar-to-endocrine conversion. Curr Biol 21: 712-717.
24. Kellendonk C, Tronche Fo, Monaghan AP, Angrand P-O, Stewart F, et al. (1996) Regulation of Cre Recombinase Activity by the Synthetic Steroid RU 486. Nucleic Acids Research 24: 1404-1411.
25. Zhang Y, Riesterer C, Ayrall A-M, Sablitzky F, Littlewood TD, et al. (1996) Inducible Site-Directed Recombination in Mouse Embryonic Stem Cells. Nucleic Acids Research 24: 543-548. (Pubitemid 26085826)
26. Awatramani R, Soriano P, Rodriguez C, Mai JJ, Dymecki SM (2003) Cryptic boundaries in roof plate and choroid plexus identified by intersectional gene activation. Nat Genet 35: 70-75. (Pubitemid 37048598)
27. Hirsch MR, d'Autreaux F, Dymecki SM, Brunet JF, Goridis C (2013) A Phox2bColon, two colonsFLPo transgenic mouse line suitable for intersectional genetics. Genesis.
28. Dymecki SM, Ray RS, Kim JC (2010) Mapping cell fate and function using recombinase-based intersectional strategies. Methods Enzymol 477: 183-213.
29. Halloran MC, Sato-Maeda M, Warren JT, Su F, Lele Z, et al. (2000) Laserinduced gene expression in specific cells of transgenic zebrafish. Development 127: 1953-1960. (Pubitemid 30311798)
30. Adam A, Bartfai R, Lele Z, Krone PH, Orban L (2000) Heat-inducible expression of a reporter gene detected by transient assay in zebrafish. Exp Cell Res 256: 282-290. (Pubitemid 30211190)
31. Knopf F, Schnabel K, Haase C, Pfeifer K, Anastassiadis K, et al. (2010) Dually inducible TetON systems for tissue-specific conditional gene expression in zebrafish. Proc Natl Acad Sci U S A 107: 19933-19938.
32. Huang CJ, Jou TS, Ho YL, Lee WH, Jeng YT, et al. (2005) Conditional expression of a myocardium-specific transgene in zebrafish transgenic lines. Dev Dyn 233: 1294-1303.
33. Emelyanov A, Parinov S (2008) Mifepristone-inducible LexPR system to drive and control gene expression in transgenic zebrafish. Dev Biol 320: 113-121.
34. Maddison LA, Lu J, Chen W (2011) Generating conditional mutations in zebrafish using gene-trap mutagenesis. Methods Cell Biol 104: 1-22.
35. Provost E, Rhee J, Leach SD (2007) Viral 2A peptides allow expression of multiple proteins from a single ORF in transgenic zebrafish embryos. Genesis 45: 625-629. (Pubitemid 350099585)
36. Bedell VM, Wang Y, Campbell JM, Poshusta TL, Starker CG, et al. (2012) In vivo genome editing using a high-efficiency TALEN system. Nature 491: 114-118.
37. Hwang WY, Fu Y, Reyon D, Maeder ML, Tsai SQ, et al. (2013) Efficient genome editing in zebrafish using a CRISPR-Cas system. Nat Biotechnol 31: 227-229.