-
1
-
-
84879476708
-
Phase III, multicenter, randomized trial of maintenance chemotherapy versus observation in patients with metastatic breast cancer after achieving disease control with six cycles of gemcitabine plus paclitaxel as first-line chemotherapy: KCSG-BR07-02
-
Y.H. Park, K.H. Jung, and S.A. Im et al. Phase III, multicenter, randomized trial of maintenance chemotherapy versus observation in patients with metastatic breast cancer after achieving disease control with six cycles of gemcitabine plus paclitaxel as first-line chemotherapy: KCSG-BR07-02 J Clin Oncol 31 14 2013 1732 1739
-
(2013)
J Clin Oncol
, vol.31
, Issue.14
, pp. 1732-1739
-
-
Park, Y.H.1
Jung, K.H.2
Im, S.A.3
-
2
-
-
84859101072
-
A genome-wide association study identifies four genetic markers for hematological toxicities in cancer patients receiving gemcitabine therapy
-
K. Kiyotani, S. Uno, and T. Mushiroda et al. A genome-wide association study identifies four genetic markers for hematological toxicities in cancer patients receiving gemcitabine therapy Pharmacogenet Genomics 22 2012 229 235
-
(2012)
Pharmacogenet Genomics
, vol.22
, pp. 229-235
-
-
Kiyotani, K.1
Uno, S.2
Mushiroda, T.3
-
3
-
-
84857691265
-
Transporters that translocate nucleosides and structural similar drugs: Structural requirements for substrate recognition
-
P. Cano-Soldado, and M. Pastor-Anglada Transporters that translocate nucleosides and structural similar drugs: structural requirements for substrate recognition Med Res Rev 32 2012 428 457
-
(2012)
Med Res Rev
, vol.32
, pp. 428-457
-
-
Cano-Soldado, P.1
Pastor-Anglada, M.2
-
4
-
-
84874029063
-
Pharmacogenomics of gemcitabine metabolism: Functional analysis of genetic variants in cytidine deaminase and deoxycytidine kinase
-
J.A. Baker, E.R. Wickremsinhe, and C.H. Li et al. Pharmacogenomics of gemcitabine metabolism: functional analysis of genetic variants in cytidine deaminase and deoxycytidine kinase Drug Metab Dispos 41 2013 541 545
-
(2013)
Drug Metab Dispos
, vol.41
, pp. 541-545
-
-
Baker, J.A.1
Wickremsinhe, E.R.2
Li, C.H.3
-
5
-
-
84864408425
-
Effect of genetic polymorphisms on therapeutic response and clinical outcomes in pancreatic cancer patients treated with gemcitabine
-
H.I. Woo, K.K. Kim, and H. Choi et al. Effect of genetic polymorphisms on therapeutic response and clinical outcomes in pancreatic cancer patients treated with gemcitabine Pharmacogenomics 13 2012 1023 1035
-
(2012)
Pharmacogenomics
, vol.13
, pp. 1023-1035
-
-
Woo, H.I.1
Kim, K.K.2
Choi, H.3
-
6
-
-
84879846126
-
Influence of CYP2C8 polymorphisms on the hydroxylation metabolism of paclitaxel, repaglinide, and ibuprofen enantiomers in vitro
-
L. Yu, D. Shi, L. Ma, Q. Zhou, and S. Zeng Influence of CYP2C8 polymorphisms on the hydroxylation metabolism of paclitaxel, repaglinide, and ibuprofen enantiomers in vitro Biopharm Drug Dispos 34 5 2013 278 287
-
(2013)
Biopharm Drug Dispos
, vol.34
, Issue.5
, pp. 278-287
-
-
Yu, L.1
Shi, D.2
Ma, L.3
Zhou, Q.4
Zeng, S.5
-
7
-
-
84863981895
-
CYP2C8â̂ - 3 predicts benefit/risk profile in breast cancer patients receiving neoadjuvant paclitaxel
-
D.L. Hertz, A.A. Motsinger-Reif, and A. Drobish et al. CYP2C8â̂ - 3 predicts benefit/risk profile in breast cancer patients receiving neoadjuvant paclitaxel Breast Cancer Res Treat 134 2012 401 410
-
(2012)
Breast Cancer Res Treat
, vol.134
, pp. 401-410
-
-
Hertz, D.L.1
Motsinger-Reif, A.A.2
Drobish, A.3
-
8
-
-
33750340905
-
Pharmacogenetic screening of CYP3A and ABCB1 in relation to population pharmacokinetics of docetaxel
-
T.M. Bosch, A.D. Huitema, and V.D. Doodeman et al. Pharmacogenetic screening of CYP3A and ABCB1 in relation to population pharmacokinetics of docetaxel Clin Cancer Res 12 2006 5786 5793
-
(2006)
Clin Cancer Res
, vol.12
, pp. 5786-5793
-
-
Bosch, T.M.1
Huitema, A.D.2
Doodeman, V.D.3
-
9
-
-
32944468151
-
Mdr-1 single nucleotide polymorphisms in ovarian cancer tissue: G2677T/A correlates with response to paclitaxel chemotherapy
-
H. Green, P. Soderkvist, P. Rosenberg, G. Horvath, and C. Peterson Mdr-1 single nucleotide polymorphisms in ovarian cancer tissue: G2677T/A correlates with response to paclitaxel chemotherapy Clin Cancer Res 12 2006 854 859
-
(2006)
Clin Cancer Res
, vol.12
, pp. 854-859
-
-
Green, H.1
Soderkvist, P.2
Rosenberg, P.3
Horvath, G.4
Peterson, C.5
-
10
-
-
60549112572
-
Association of the ABCB1 gene polymorphisms 2677G>T/A and 3435C>T with clinical outcomes of paclitaxel monotherapy in metastatic breast cancer patients
-
H. Chang, S.Y. Rha, and H.C. Jeung et al. Association of the ABCB1 gene polymorphisms 2677G>T/A and 3435C>T with clinical outcomes of paclitaxel monotherapy in metastatic breast cancer patients Ann Oncol 20 2009 272 277
-
(2009)
Ann Oncol
, vol.20
, pp. 272-277
-
-
Chang, H.1
Rha, S.Y.2
Jeung, H.C.3
-
11
-
-
76049095127
-
Association of the ABCB1 3435C>T polymorphism and treatment outcomes in advanced gastric cancer patients treated with paclitaxel-based chemotherapy
-
H. Chang, S.Y. Rha, and H.C. Jeung et al. Association of the ABCB1 3435C>T polymorphism and treatment outcomes in advanced gastric cancer patients treated with paclitaxel-based chemotherapy Oncol Rep 23 2010 271 278
-
(2010)
Oncol Rep
, vol.23
, pp. 271-278
-
-
Chang, H.1
Rha, S.Y.2
Jeung, H.C.3
-
13
-
-
84865054217
-
ABCB1, FCGR2A, and FCGR3A polymorphisms in patients with HER2-positive metastatic breast cancer who were treated with first-line taxane plus trastuzumab chemotherapy
-
J.W. Kim, J.H. Kim, and S.A. Im et al. ABCB1, FCGR2A, and FCGR3A polymorphisms in patients with HER2-positive metastatic breast cancer who were treated with first-line taxane plus trastuzumab chemotherapy Oncology 83 2012 218 227
-
(2012)
Oncology
, vol.83
, pp. 218-227
-
-
Kim, J.W.1
Kim, J.H.2
Im, S.A.3
-
14
-
-
84864411377
-
Pathway-based pharmacogenomics of gemcitabine pharmacokinetics in patients with solid tumors
-
A.K. Mitra, M.N. Kirstein, and A. Khatri et al. Pathway-based pharmacogenomics of gemcitabine pharmacokinetics in patients with solid tumors Pharmacogenomics 13 2012 1009 1021
-
(2012)
Pharmacogenomics
, vol.13
, pp. 1009-1021
-
-
Mitra, A.K.1
Kirstein, M.N.2
Khatri, A.3
-
15
-
-
84865474189
-
Levels of gemcitabine transport and metabolism proteins predict survival times of patients treated with gemcitabine for pancreatic adenocarcinoma
-
66474
-
R. Marechal, J.B. Bachet, and J.R. Mackey et al. Levels of gemcitabine transport and metabolism proteins predict survival times of patients treated with gemcitabine for pancreatic adenocarcinoma Gastroenterology 143 664-74 2012 e1 e6
-
(2012)
Gastroenterology
, vol.143
-
-
Marechal, R.1
Bachet, J.B.2
Mackey, J.R.3
-
16
-
-
84862908671
-
A genome-wide association study of overall survival in pancreatic cancer patients treated with gemcitabine in CALGB 80303
-
F. Innocenti, K. Owzar, and N.L. Cox et al. A genome-wide association study of overall survival in pancreatic cancer patients treated with gemcitabine in CALGB 80303 Clin Cancer Res 18 2012 577 584
-
(2012)
Clin Cancer Res
, vol.18
, pp. 577-584
-
-
Innocenti, F.1
Owzar, K.2
Cox, N.L.3
-
17
-
-
84874590658
-
A kinome screen identifies checkpoint kinase 1 (CHK1) as a sensitizer for RRM1-dependent gemcitabine efficacy
-
J. Zhou, Z. Chen, and A. Malysa et al. A kinome screen identifies checkpoint kinase 1 (CHK1) as a sensitizer for RRM1-dependent gemcitabine efficacy PLoS One 8 2013 e58091
-
(2013)
PLoS One
, vol.8
, pp. 58091
-
-
Zhou, J.1
Chen, Z.2
Malysa, A.3
-
18
-
-
84873800406
-
Predictive impact of RRM1 protein expression on vinorelbine efficacy in NSCLC patients randomly assigned in a chemotherapy phase III trial
-
A.C. Vilmar, E. Santoni-Rugiu, and J.B. Sorensen Predictive impact of RRM1 protein expression on vinorelbine efficacy in NSCLC patients randomly assigned in a chemotherapy phase III trial Ann Oncol 24 2013 309 314
-
(2013)
Ann Oncol
, vol.24
, pp. 309-314
-
-
Vilmar, A.C.1
Santoni-Rugiu, E.2
Sorensen, J.B.3
-
19
-
-
84863724265
-
Association study of 27 annotated genes for clozapine pharmacogenetics: Validation of preexisting studies and identification of a new candidate gene, ABCB1, for treatment response
-
S.T. Lee, S. Ryu, and S.R. Kim et al. Association study of 27 annotated genes for clozapine pharmacogenetics: validation of preexisting studies and identification of a new candidate gene, ABCB1, for treatment response J Clin Psychopharmacol 32 2012 441 448
-
(2012)
J Clin Psychopharmacol
, vol.32
, pp. 441-448
-
-
Lee, S.T.1
Ryu, S.2
Kim, S.R.3
-
20
-
-
84861329544
-
Polymorphic markers associated with severe oxaliplatin-induced, chronic peripheral neuropathy in colon cancer patients
-
H.H. Won, J. Lee, and J.O. Park et al. Polymorphic markers associated with severe oxaliplatin-induced, chronic peripheral neuropathy in colon cancer patients Cancer 118 2012 2828 2836
-
(2012)
Cancer
, vol.118
, pp. 2828-2836
-
-
Won, H.H.1
Lee, J.2
Park, J.O.3
-
21
-
-
50549096593
-
Gemcitabine plus Paclitaxel versus Paclitaxel monotherapy in patients with metastatic breast cancer and prior anthracycline treatment
-
K.S. Albain, S.M. Nag, and G. Calderillo-Ruiz et al. Gemcitabine plus Paclitaxel versus Paclitaxel monotherapy in patients with metastatic breast cancer and prior anthracycline treatment J Clin Oncol 26 2008 3950 3957
-
(2008)
J Clin Oncol
, vol.26
, pp. 3950-3957
-
-
Albain, K.S.1
Nag, S.M.2
Calderillo-Ruiz, G.3
-
22
-
-
74949112149
-
Single nucleotide polymorphisms of gemcitabine metabolic genes and pancreatic cancer survival and drug toxicity
-
T. Okazaki, M. Javle, M. Tanaka, J.L. Abbruzzese, and D. Li Single nucleotide polymorphisms of gemcitabine metabolic genes and pancreatic cancer survival and drug toxicity Clin Cancer Res 16 2010 320 329
-
(2010)
Clin Cancer Res
, vol.16
, pp. 320-329
-
-
Okazaki, T.1
Javle, M.2
Tanaka, M.3
Abbruzzese, J.L.4
Li, D.5
-
23
-
-
84855932882
-
Gemcitabine metabolic pathway genetic polymorphisms and response in patients with non-small cell lung cancer
-
L. Li, D.J. Schaid, and B.L. Fridley et al. Gemcitabine metabolic pathway genetic polymorphisms and response in patients with non-small cell lung cancer Pharmacogenet Genomics 22 2012 105 116
-
(2012)
Pharmacogenet Genomics
, vol.22
, pp. 105-116
-
-
Li, L.1
Schaid, D.J.2
Fridley, B.L.3
-
24
-
-
79959548041
-
The ribonucleotide reductase large subunit (RRM1) as a predictive factor in patients with cancer
-
L.P. Jordheim, P. Seve, O. Tredan, and C. Dumontet The ribonucleotide reductase large subunit (RRM1) as a predictive factor in patients with cancer Lancet Oncol 12 2011 693 702
-
(2011)
Lancet Oncol
, vol.12
, pp. 693-702
-
-
Jordheim, L.P.1
Seve, P.2
Tredan, O.3
Dumontet, C.4
-
25
-
-
83655164249
-
The influence of gemcitabine pathway polymorphisms on treatment outcome in patients with malignant mesothelioma
-
N. Erculj, V. Kovac, J. Hmeljak, A. Franko, M. Dodic-Fikfak, and V. Dolzan The influence of gemcitabine pathway polymorphisms on treatment outcome in patients with malignant mesothelioma Pharmacogenet Genomics 22 2012 58 68
-
(2012)
Pharmacogenet Genomics
, vol.22
, pp. 58-68
-
-
Erculj, N.1
Kovac, V.2
Hmeljak, J.3
Franko, A.4
Dodic-Fikfak, M.5
Dolzan, V.6
-
26
-
-
79952983932
-
Association of RRM1 -37A>C polymorphism with clinical outcome in colorectal cancer patients treated with gemcitabine-based chemotherapy
-
J. Rodriguez, V. Boni, and A. Hernandez et al. Association of RRM1 -37A>C polymorphism with clinical outcome in colorectal cancer patients treated with gemcitabine-based chemotherapy Eur J Cancer 47 2011 839 847
-
(2011)
Eur J Cancer
, vol.47
, pp. 839-847
-
-
Rodriguez, J.1
Boni, V.2
Hernandez, A.3
-
27
-
-
34447137381
-
An association between RRM1 haplotype and gemcitabine-induced neutropenia in breast cancer patients
-
S.Y. Rha, H.C. Jeung, and Y.H. Choi et al. An association between RRM1 haplotype and gemcitabine-induced neutropenia in breast cancer patients Oncologist 12 2007 622 630
-
(2007)
Oncologist
, vol.12
, pp. 622-630
-
-
Rha, S.Y.1
Jeung, H.C.2
Choi, Y.H.3
|