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Volumn 119, Issue 1, 2014, Pages 19-24

Expression and clinicopathological significance of miR-146a in hepatocellular carcinoma tissues

Author keywords

Hepatocellular carcinoma; Metastasis; MiR 146a; Oncogenes; Paraffin embedded tissues; Pathology; RT qPCR; Tumor biology

Indexed keywords

BIOLOGICAL MARKER; MICRORNA; MIRN146 MICRORNA, HUMAN; PRIMER DNA;

EID: 84894038930     PISSN: 03009734     EISSN: None     Source Type: Journal    
DOI: 10.3109/03009734.2013.856970     Document Type: Article
Times cited : (70)

References (49)
  • 1
    • 80051768100 scopus 로고    scopus 로고
    • Molecular pathogenesis of hepatocellular carcinoma: Altering transforming growth factor-beta signaling in hepatocarcinogenesis
    • Yamazaki K, Masugi Y, Sakamoto M. Molecular pathogenesis of hepatocellular carcinoma: altering transforming growth factor-beta signaling in hepatocarcinogenesis. Dig Dis. 2011;29:284-8.
    • (2011) Dig Dis , vol.29 , pp. 284-288
    • Yamazaki, K.1    Masugi, Y.2    Sakamoto, M.3
  • 2
    • 0035888074 scopus 로고    scopus 로고
    • Estimating the world cancer burden: Globocan 2000
    • Parkin DM, Bray F, Ferlay J, Pisani P. Estimating the world cancer burden: Globocan 2000. Int J Cancer. 2001;94: 153-6.
    • (2001) Int J Cancer , vol.94 , pp. 153-156
    • Parkin, D.M.1    Bray, F.2    Ferlay, J.3    Pisani, P.4
  • 3
    • 84860799379 scopus 로고    scopus 로고
    • The hypothesis of an effective strategy for resistance of hepatocellular carcinoma to therapyautophagy
    • Liu B, Mao A, Liu D. The hypothesis of an effective strategy for resistance of hepatocellular carcinoma to therapyautophagy. West Indian Med J. 2011;60:666-8.
    • (2011) West Indian Med J , vol.60 , pp. 666-668
    • Liu, B.1    Mao, A.2    Liu, D.3
  • 4
    • 84855313808 scopus 로고    scopus 로고
    • Hepatocellular carcinoma in 2011 and beyond: From the pathogenesis to molecular targeted therapy
    • Kudo M. Hepatocellular carcinoma in 2011 and beyond: from the pathogenesis to molecular targeted therapy. Oncology. 2011;81:1-10.
    • (2011) Oncology , vol.81 , pp. 1-10
    • Kudo, M.1
  • 5
    • 84872868918 scopus 로고    scopus 로고
    • The molecular pathogenesis and clinical implications of hepatocellular carcinoma
    • Meguro M, Mizuguchi T, Kawamoto M, Hirata K. The molecular pathogenesis and clinical implications of hepatocellular carcinoma. Int J Hepatol. 2011;2011:818672.
    • (2011) Int J Hepatol , vol.2011 , pp. 818672
    • Meguro, M.1    Mizuguchi, T.2    Kawamoto, M.3    Hirata, K.4
  • 6
    • 79959304448 scopus 로고    scopus 로고
    • The role of oncogenic viruses in the pathogenesis of hepatocellular carcinoma
    • vii-x
    • Zemel R, Issachar A, Tur-Kaspa R. The role of oncogenic viruses in the pathogenesis of hepatocellular carcinoma. Clin Liver Dis. 2011;15:261-79; vii-x.
    • (2011) Clin Liver Dis , vol.15 , pp. 261-279
    • Zemel, R.1    Issachar, A.2    Tur-Kaspa, R.3
  • 8
    • 84879838477 scopus 로고    scopus 로고
    • IL28B polymorphisms predict the virological response to standard therapy in patients with chronic hepatitis C virus genotype 4 infection
    • Abdo AA, Al-Ahdal MN, Khalid SS, Helmy A, Sanai FM, Alswat K, et al. IL28B polymorphisms predict the virological response to standard therapy in patients with chronic hepatitis C virus genotype 4 infection. Hepatol Int. 2013;7:533-8.
    • (2013) Hepatol Int , vol.7 , pp. 533-538
    • Abdo, A.A.1    Al-Ahdal, M.N.2    Khalid, S.S.3    Helmy, A.4    Sanai, F.M.5    Alswat, K.6
  • 9
    • 77949658391 scopus 로고    scopus 로고
    • Clinicopathological significance of RASSF1A reduced expression and hypermethylation in hepatocellular carcinoma
    • Hu L, Chen G, Yu H, Qiu X. Clinicopathological significance of RASSF1A reduced expression and hypermethylation in hepatocellular carcinoma. Hepatol Int. 2010;4:423-32.
    • (2010) Hepatol Int , vol.4 , pp. 423-432
    • Hu, L.1    Chen, G.2    Yu, H.3    Qiu, X.4
  • 10
    • 65349154749 scopus 로고    scopus 로고
    • Expression of decoy receptor 3 in liver tissue microarrays
    • Chen G, Luo D. Expression of decoy receptor 3 in liver tissue microarrays. Natl Med J India. 2008;21:275-8.
    • (2008) Natl Med J India , vol.21 , pp. 275-278
    • Chen, G.1    Luo, D.2
  • 11
    • 51049117490 scopus 로고    scopus 로고
    • Expression of heparanase in hepatocellular carcinoma has prognostic significance: A tissue microarray study
    • Chen G, Dang YW, Luo DZ, Feng ZB, Tang XL. Expression of heparanase in hepatocellular carcinoma has prognostic significance: a tissue microarray study. Oncol Res. 2008;17: 183-9.
    • (2008) Oncol Res , vol.17 , pp. 183-189
    • Chen, G.1    Dang, Y.W.2    Luo, D.Z.3    Feng, Z.B.4    Tang, X.L.5
  • 12
    • 34249672213 scopus 로고    scopus 로고
    • Hepatic local micro-environmental immune status in hepatocellular carcinoma and cirrhotic tissues
    • Chen G, LuoDZ, Liu L, Feng ZB, Guo F, Li P.Hepatic local micro-environmental immune status in hepatocellular carcinoma and cirrhotic tissues. West Indian Med J. 2006;55: 403-8.
    • (2006) West Indian Med J , vol.55 , pp. 403-408
    • Chen, G.1    Luodz Liu, L.2    Feng, Z.B.3    Guo, F.4    Li, P.5
  • 13
    • 56749136445 scopus 로고    scopus 로고
    • Over-expression of decoy receptor 3 in gastric precancerous lesions and carcinoma
    • Chen G, Luo D. Over-expression of decoy receptor 3 in gastric precancerous lesions and carcinoma. Ups J Med Sci. 2008;113:297-304.
    • (2008) Ups J Med Sci , vol.113 , pp. 297-304
    • Chen, G.1    Luo, D.2
  • 14
    • 77958530304 scopus 로고    scopus 로고
    • Significance of decoy receptor 3 in sera of hepatocellular carcinoma patients
    • Yang M, Chen G, Dang Y, Luo D. Significance of decoy receptor 3 in sera of hepatocellular carcinoma patients. Ups J Med Sci. 2010;115:232-7.
    • (2010) Ups J Med Sci , vol.115 , pp. 232-237
    • Yang, M.1    Chen, G.2    Dang, Y.3    Luo, D.4
  • 15
    • 84869035506 scopus 로고    scopus 로고
    • PTEN enhances the sensitivity of human hepatocellular carcinoma cells to sorafenib
    • Ruan ZP, Xu R, Lv Y, Tian T, Wang WJ, Guo H, et al. PTEN enhances the sensitivity of human hepatocellular carcinoma cells to sorafenib. Oncol Res. 2012;20:113-21.
    • (2012) Oncol Res , vol.20 , pp. 113-121
    • Ruan, Z.P.1    Xu, R.2    Lv, Y.3    Tian, T.4    Wang, W.J.5    Guo, H.6
  • 16
    • 58149376548 scopus 로고    scopus 로고
    • Molecular mechanisms of hepatocellular carcinoma
    • Aravalli RN, Steer CJ, Cressman EN. Molecular mechanisms of hepatocellular carcinoma. Hepatology. 2008;48:2047-63.
    • (2008) Hepatology , vol.48 , pp. 2047-2063
    • Aravalli, R.N.1    Steer, C.J.2    Cressman, E.N.3
  • 17
  • 18
    • 79953888460 scopus 로고    scopus 로고
    • The functional role of long non-coding RNA in human carcinomas
    • Gibb EA, Brown CJ, Lam WL. The functional role of long non-coding RNA in human carcinomas. Mol Cancer. 2011; 10:38.
    • (2011) Mol Cancer , vol.10 , pp. 38
    • Gibb, E.A.1    Brown, C.J.2    Lam, W.L.3
  • 19
    • 84873704949 scopus 로고    scopus 로고
    • Quantitative PCR analysis of blood- and saliva-specific microRNA markers following solid-phase DNAextraction
    • Omelia EJ, Uchimoto ML, Williams G. Quantitative PCR analysis of blood- and saliva-specific microRNA markers following solid-phase DNAextraction. Anal Biochem. 2013;435: 120-2.
    • (2013) Anal Biochem , vol.435 , pp. 120-122
    • Omelia, E.J.1    Uchimoto, M.L.2    Williams, G.3
  • 20
    • 82255173788 scopus 로고    scopus 로고
    • Micro-RNAs as diagnostic or prognostic markers in human epithelial malignancies
    • Hui A, How C, Ito E, Liu FF. Micro-RNAs as diagnostic or prognostic markers in human epithelial malignancies. BMC Cancer. 2011;11:500.
    • (2011) BMC Cancer , vol.11 , pp. 500
    • Hui, A.1    How, C.2    Ito, E.3    Liu, F.F.4
  • 21
    • 84859920413 scopus 로고    scopus 로고
    • MicroRNA in cancer: New hopes for antineoplastic chemotherapy
    • Di Leva G, Briskin D, Croce CM. MicroRNA in cancer: new hopes for antineoplastic chemotherapy. Ups J Med Sci. 2012; 117:202-16.
    • (2012) Ups J Med Sci , vol.117 , pp. 202-216
    • Di Leva, G.1    Briskin, D.2    Croce, C.M.3
  • 22
    • 72449142765 scopus 로고    scopus 로고
    • MicroRNAs: Predictors and modifiers of chemo- and radiotherapy in different tumour types
    • Hummel R, Hussey DJ, Haier J. MicroRNAs: predictors and modifiers of chemo- and radiotherapy in different tumour types. Eur J Cancer. 2010;46:298-311.
    • (2010) Eur J Cancer , vol.46 , pp. 298-311
    • Hummel, R.1    Hussey, D.J.2    Haier, J.3
  • 23
    • 77649274485 scopus 로고    scopus 로고
    • MicroRNA expression profiling by bead array technology in human tumor cell lines treated with interferon-alpha-2a
    • Siegrist F, Singer T, Certa U. MicroRNA expression profiling by bead array technology in human tumor cell lines treated with interferon-alpha-2a. Biol Proced Online. 2009;11:113-29.
    • (2009) Biol Proced Online , vol.11 , pp. 113-129
    • Siegrist, F.1    Singer, T.2    Certa, U.3
  • 24
    • 48149093106 scopus 로고    scopus 로고
    • MicroRNAs: Regulators of oncogenesis and stemness
    • Papagiannakopoulos T, Kosik KS. MicroRNAs: regulators of oncogenesis and stemness. BMC Med. 2008;6:15.
    • (2008) BMC Med , vol.6 , pp. 15
    • Papagiannakopoulos, T.1    Kosik, K.S.2
  • 25
    • 84862777528 scopus 로고    scopus 로고
    • MicroRNA profiling of hepatocarcinogenesis identifies C19MC cluster as a novel prognostic biomarker in hepatocellular carcinoma
    • Augello C, Vaira V, Caruso L, Destro A, Maggioni M, Park YN, et al. MicroRNA profiling of hepatocarcinogenesis identifies C19MC cluster as a novel prognostic biomarker in hepatocellular carcinoma. Liver Int. 2012;32:772-82.
    • (2012) Liver Int , vol.32 , pp. 772-782
    • Augello, C.1    Vaira, V.2    Caruso, L.3    Destro, A.4    Maggioni, M.5    Park, Y.N.6
  • 27
    • 79551507191 scopus 로고    scopus 로고
    • MicroRNA profile predicts recurrence after resection in patients with hepatocellular carcinoma within the Milan Criteria
    • Sato F, Hatano E, Kitamura K, Myomoto A, Fujiwara T, Takizawa S, et al. MicroRNA profile predicts recurrence after resection in patients with hepatocellular carcinoma within the Milan Criteria. PLoS ONE. 2011;6:e16435.
    • (2011) PLoS ONE , vol.6
    • Sato, F.1    Hatano, E.2    Kitamura, K.3    Myomoto, A.4    Fujiwara, T.5    Takizawa, S.6
  • 28
    • 78649403064 scopus 로고    scopus 로고
    • Proteomic identification of microRNA-122a target proteins in hepatocellular carcinoma
    • Diao S, Zhang JF, Wang H, He ML, Lin MC, Chen Y, et al. Proteomic identification of microRNA-122a target proteins in hepatocellular carcinoma. Proteomics. 2010;10:3723-31.
    • (2010) Proteomics , vol.10 , pp. 3723-3731
    • Diao, S.1    Zhang, J.F.2    Wang, H.3    He, M.L.4    Lin, M.C.5    Chen, Y.6
  • 29
    • 77956249298 scopus 로고    scopus 로고
    • MicroRNA-122 as a regulator of mitochondrial metabolic gene network in hepatocellular carcinoma
    • Burchard J, Zhang C, Liu AM, Poon RT, Lee NP, Wong KF, et al. MicroRNA-122 as a regulator of mitochondrial metabolic gene network in hepatocellular carcinoma. Mol Syst Biol. 2010;6:402.
    • (2010) Mol Syst Biol , vol.6 , pp. 402
    • Burchard, J.1    Zhang, C.2    Liu, A.M.3    Poon, R.T.4    Lee, N.P.5    Wong, K.F.6
  • 30
    • 79251638583 scopus 로고    scopus 로고
    • Serum microRNA characterization identifies miR-885-5p as a potential marker for detecting liver pathologies
    • Gui J, Tian Y, Wen X, Zhang W, Zhang P, Gao J, et al. Serum microRNA characterization identifies miR-885-5p as a potential marker for detecting liver pathologies. Clin Sci (Lond). 2011;120:183-93.
    • (2011) Clin Sci (Lond) , vol.120 , pp. 183-193
    • Gui, J.1    Tian, Y.2    Wen, X.3    Zhang, W.4    Zhang, P.5    Gao, J.6
  • 31
    • 84877263372 scopus 로고    scopus 로고
    • Expression of microRNAs, miR-21, miR-31, miR-122, miR-145, miR- 146a, miR-200c, miR-221, miR-222, and miR-223 in patients with hepatocellular carcinoma or intrahepatic cholangiocarcinoma and its prognostic significance
    • Karakatsanis A, Papaconstantinou I, Gazouli M, Lyberopoulou A, Polymeneas G, Voros D. Expression of microRNAs, miR-21, miR-31, miR-122, miR-145, miR- 146a, miR-200c, miR-221, miR-222, and miR-223 in patients with hepatocellular carcinoma or intrahepatic cholangiocarcinoma and its prognostic significance. Mol Carcinog. 2013;52: 297-303.
    • (2013) Mol Carcinog , vol.52 , pp. 297-303
    • Karakatsanis, A.1    Papaconstantinou, I.2    Gazouli, M.3    Lyberopoulou, A.4    Polymeneas, G.5    Voros, D.6
  • 32
    • 84875424861 scopus 로고    scopus 로고
    • MiR-146a inhibits cell growth, cell migration and induces apoptosis in non-small cell lung cancer cells
    • Chen G, Umelo IA, Lv S, Teugels E, Fostier K, Kronenberger P, et al. MiR-146a inhibits cell growth, cell migration and induces apoptosis in non-small cell lung cancer cells. PLoS ONE. 2013;8:e60317.
    • (2013) PLoS ONE , vol.8
    • Chen, G.1    Umelo, I.A.2    Lv, S.3    Teugels, E.4    Fostier, K.5    Kronenberger, P.6
  • 33
    • 84876042176 scopus 로고    scopus 로고
    • Underexpression of miR- 34a in hepatocellular carcinoma and its contribution towards enhancement of proliferating inhibitory effects of agents targeting c-MET
    • Dang Y, Luo D, Rong M, Chen G. Underexpression of miR- 34a in hepatocellular carcinoma and its contribution towards enhancement of proliferating inhibitory effects of agents targeting c-MET. PLoS ONE. 2013;8:e61054.
    • (2013) PLoS ONE , vol.8
    • Dang, Y.1    Luo, D.2    Rong, M.3    Chen, G.4
  • 34
    • 84872182721 scopus 로고    scopus 로고
    • Increased miR-221 expression in hepatocellular carcinoma tissues and its role in enhancing cell growth and inhibiting apoptosis in vitro
    • Rong M, Chen G, Dang Y. Increased miR-221 expression in hepatocellular carcinoma tissues and its role in enhancing cell growth and inhibiting apoptosis in vitro. BMC Cancer. 2013; 13:21.
    • (2013) BMC Cancer , vol.13 , pp. 21
    • Rong, M.1    Chen, G.2    Dang, Y.3
  • 35
    • 84862791294 scopus 로고    scopus 로고
    • Targeting the epidermal growth factor receptor in non-small cell lung cancer cells: The effect of combining RNA interference with tyrosine kinase inhibitors or cetuximab
    • Chen G, Kronenberger P, Teugels E, Umelo IA, De Greve J. Targeting the epidermal growth factor receptor in non-small cell lung cancer cells: the effect of combining RNA interference with tyrosine kinase inhibitors or cetuximab. BMC Med. 2012;10:28.
    • (2012) BMC Med , vol.10 , pp. 28
    • Chen, G.1    Kronenberger, P.2    Teugels, E.3    Umelo, I.A.4    De Greve, J.5
  • 36
    • 84887014620 scopus 로고    scopus 로고
    • MiR-146a enhances angiogenic activity of endothelial cells in hepatocellular carcinoma by promoting PDGFRA expression
    • Zhu K, Pan Q, Zhang X, Kong LQ, Fan J, Dai Z, et al. MiR-146a enhances angiogenic activity of endothelial cells in hepatocellular carcinoma by promoting PDGFRA expression. Carcinogenesis. 2013;34:2071-9.
    • (2013) Carcinogenesis , vol.34 , pp. 2071-2079
    • Zhu, K.1    Pan, Q.2    Zhang, X.3    Kong, L.Q.4    Fan, J.5    Dai, Z.6
  • 37
    • 53349177819 scopus 로고    scopus 로고
    • Characterization of microRNAs in serum: A novel class of biomarkers for diagnosis of cancer and other diseases
    • Chen X, Ba Y, Ma L, Cai X, Yin Y, Wang K, et al. Characterization of microRNAs in serum: a novel class of biomarkers for diagnosis of cancer and other diseases. Cell Res. 2008; 18:997-1006.
    • (2008) Cell Res , vol.18 , pp. 997-1006
    • Chen, X.1    Ba, Y.2    Ma, L.3    Cai, X.4    Yin, Y.5    Wang, K.6
  • 38
    • 78649325763 scopus 로고    scopus 로고
    • Serum micro- RNAs as non-invasive biomarkers for cancer
    • Brase JC, Wuttig D, Kuner R, Sultmann H. Serum micro- RNAs as non-invasive biomarkers for cancer. Mol Cancer. 2010;9:306.
    • (2010) Mol Cancer , vol.9 , pp. 306
    • Brase, J.C.1    Wuttig, D.2    Kuner, R.3    Sultmann, H.4
  • 39
    • 84874252642 scopus 로고    scopus 로고
    • The association between two common polymorphisms in MicroRNAs and hepatocellular carcinomariskinAsianpopulation
    • Hu M, Zhao L, Hu S, Yang J. The association between two common polymorphisms in MicroRNAs and hepatocellular carcinomariskinAsianpopulation. PLoSONE.2013;8:e57012.
    • (2013) PLoSONE , vol.8
    • Hu, M.1    Zhao, L.2    Hu, S.3    Yang, J.4
  • 40
    • 84863102484 scopus 로고    scopus 로고
    • Lack of association of two common polymorphisms rs2910164 and rs11614913 with susceptibility to hepatocellular carcinoma: A meta-analysis
    • Wang Z, Cao Y, Jiang C, Yang G, Wu J, Ding Y. Lack of association of two common polymorphisms rs2910164 and rs11614913 with susceptibility to hepatocellular carcinoma: a meta-analysis. PLoS ONE. 2012;7:e40039.
    • (2012) PLoS ONE , vol.7
    • Wang, Z.1    Cao, Y.2    Jiang, C.3    Yang, G.4    Wu, J.5    Ding, Y.6
  • 41
    • 56049092548 scopus 로고    scopus 로고
    • A functional polymorphism in the miR-146a gene is associated with the risk for hepatocellular carcinoma
    • Xu T, Zhu Y, Wei QK, Yuan Y, Zhou F, Ge YY, et al. A functional polymorphism in the miR-146a gene is associated with the risk for hepatocellular carcinoma. Carcinogenesis. 2008;29:2126-31.
    • (2008) Carcinogenesis , vol.29 , pp. 2126-2131
    • Xu, T.1    Zhu, Y.2    Wei, Q.K.3    Yuan, Y.4    Zhou, F.5    Ge, Y.Y.6
  • 42
    • 84877580425 scopus 로고    scopus 로고
    • Sex differences in microRNA regulation of gene expression: No smoke, just miRs
    • Morgan CP, Bale TL. Sex differences in microRNA regulation of gene expression: no smoke, just miRs. Biol Sex Differ. 2012;3:22.
    • (2012) Biol Sex Differ , vol.3 , pp. 22
    • Morgan, C.P.1    Bale, T.L.2
  • 43
    • 40449131878 scopus 로고    scopus 로고
    • Loss of mir-146a function in hormone-refractory prostate cancer
    • Lin SL, Chiang A, Chang D, Ying SY. Loss of mir-146a function in hormone-refractory prostate cancer. RNA. 2008; 14:417-24.
    • (2008) RNA , vol.14 , pp. 417-424
    • Lin, S.L.1    Chiang, A.2    Chang, D.3    Ying, S.Y.4
  • 44
    • 84865183734 scopus 로고    scopus 로고
    • MicroRNA-146a targets the L1 cell adhesion molecule and suppresses the metastatic potential of gastric cancer
    • Hou Z, Yin H, Chen C, Dai X, Li X, Liu B, et al. MicroRNA-146a targets the L1 cell adhesion molecule and suppresses the metastatic potential of gastric cancer. MolMed Report. 2012;6:501-6.
    • (2012) MolMed Report , vol.6 , pp. 501-506
    • Hou, Z.1    Yin, H.2    Chen, C.3    Dai, X.4    Li, X.5    Liu, B.6
  • 45
    • 84862908996 scopus 로고    scopus 로고
    • Increased miR-146a in gastric cancer directly targets SMAD4 and is involved in modulating cell proliferation and apoptosis
    • Xiao B, Zhu ED, Li N, Lu DS, Li W, Li BS, et al. Increased miR-146a in gastric cancer directly targets SMAD4 and is involved in modulating cell proliferation and apoptosis. Oncol Rep. 2012;27:559-66.
    • (2012) Oncol Rep , vol.27 , pp. 559-566
    • Xiao, B.1    Zhu, E.D.2    Li, N.3    Lu, D.S.4    Li, W.5    Li, B.S.6
  • 46
    • 80052319304 scopus 로고    scopus 로고
    • MicroRNA-146a inhibits glioma development by targeting Notch1
    • Mei J, Bachoo R, Zhang CL. MicroRNA-146a inhibits glioma development by targeting Notch1. Mol Cell Biol. 2011;31: 3584-92.
    • (2011) Mol Cell Biol , vol.31 , pp. 3584-3592
    • Mei, J.1    Bachoo, R.2    Zhang, C.L.3
  • 47
    • 52149102044 scopus 로고    scopus 로고
    • Expression of microRNA-146 suppresses NFkappaB activity with reduction of metastatic potential in breast cancer cells
    • Bhaumik D, Scott GK, Schokrpur S, Patil CK, Campisi J, Benz CC. Expression of microRNA-146 suppresses NFkappaB activity with reduction of metastatic potential in breast cancer cells. Oncogene. 2008;27:5643-7.
    • (2008) Oncogene , vol.27 , pp. 5643-5647
    • Bhaumik, D.1    Scott, G.K.2    Schokrpur, S.3    Patil, C.K.4    Campisi, J.5    Benz, C.C.6
  • 49
    • 84862872964 scopus 로고    scopus 로고
    • MiR-146a suppresses tumor growth and progression by targeting EGFR pathway and in a p-ERK-dependent manner in castrationresistant prostate cancer
    • XuB,WangN,WangX,TongN,ShaoN,TaoJ, et al.MiR-146a suppresses tumor growth and progression by targeting EGFR pathway and in a p-ERK-dependent manner in castrationresistant prostate cancer. Prostate. 2012;72:1171-8.
    • (2012) Prostate , vol.72 , pp. 1171-1178
    • Xu, B.1    Wang, N.2    Wang, X.3    Tong, N.4    Shao, N.5    Tao, J.6


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