Simultaneous changes in serum HMGB1 and IFN-α levels and in LAIR-1 expression on plasmatoid dendritic cells of patients with juvenile SLE.. New therapeutic options?

Lupus

Volumn 23, Issue 3, 2014, Pages 305-312

  Kanakoudi Tsakalidou, F ^a   Farmaki, E ^a   Tzimouli, V ^a   Taparkou, A ^a   Paterakis, G ^b   Trachana, M ^a   Pratsidou Gertsi, P ^a   Nalbanti, P ^a   Papachristou, F ^a  

^a ARISTOTLE UNIVERSITY OF THESSALONIKI   (Greece)

^b G GENNIMATAS GENERAL HOSPITAL   (Greece)

Author keywords

HMGB1; IFN ; Juvenile systemic lupus erythematosus; LAIR 1; plasmatoid dentritic cells

Indexed keywords

HMGB1; IFN-Α; JUVENILE SYSTEMIC LUPUS ERYTHEMATOSUS; LAIR-1; PLASMATOID DENTRITIC CELLS;

ADOLESCENT; AGE OF ONSET; BIOLOGICAL MARKERS; CASE-CONTROL STUDIES; CHILD; DENDRITIC CELLS; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; FLOW CYTOMETRY; HMGB1 PROTEIN; HUMANS; INTERFERON-ALPHA; LUPUS ERYTHEMATOSUS, SYSTEMIC; LUPUS NEPHRITIS; MALE; PROGNOSIS; RECEPTORS, IMMUNOLOGIC; SEVERITY OF ILLNESS INDEX; YOUNG ADULT;

EID: 84894037563     PISSN: 09612033     EISSN: 14770962     Source Type: Journal    
DOI: 10.1177/0961203313519157     Document Type: Article

References (31)

1. Bertsias G, Cerver R, Boumpas DT In: EULAR textbook on rheumatic diseases. London: BMJ Editions ; 2012: 476-505.
2. Courtney PA, Crockard AD, Williamson K, Irvine AE, Kennedy RJ, Bell AL. Increased apoptotic peripheral blood neutrophils in systemic lupus erythematosus: Relations with disease activity, antibodies to double stranded DNA, and neutropenia. Ann Rheum Dis. 1999 ; 58: 309-314
3. Bengtsson AA, Sturfelt G, Gullstrand B, Truedsson L. Induction of apoptosis in monocytes and lymphocytes by serum from patients with systemic lupus erythematosus - an additional mechanism to increased autoantigen load?. Clin Exp Immunol. 2004 ; 135: 535-543
4. Midgley A, McLaren Z, Moots RJ, Edwards SW, Beresford MW. The role of neutrophil apoptosis in juvenile-onset systemic lupus erythematosus. Arthritis Rheum. 2009 ; 60: 2390-2401
5. Hermann M, Voll RE, Zoller OM, Hagenhofer M, Ponner BB, Kalden JR. Impaired phagocytosis of apoptotic cell material by monocyte-derived macrophages from patients with systemic lupus erythematosus. Arthritis Rheum. 1998 ; 41: 1241-1250
6. Theophilopoulos AN, Gonzalez-Quintial R, Lawson BR, et al. Sensors of the innate immune system: Their link to rheumatic diseases. Nat Rev Rheumatol. 2010 ; 6: 146-156
7. Bianchi ME. HMGB1 loves company. J Leukoc Biol. 2009 ; 86: 573-576
8. Urbonaviciute V, Fürnrohr BG, Meister S, et al. Induction of inflammatory and immune responses by HMGB1-nucleosome complexes: Implications for the pathogenesis of SLE. J Exp Med. 2008 ; 205: 3007-3018
9. Andersson U, Wang H, Palmblad K, et al. High mobility group 1 protein (HMGB1) stimulates pro-inflammatory cytokine synthesis in human monocytes. J Exp Med. 2000 ; 192: 565-570
10. Li J, Xie H, Wen T, Liu H, Zhu W, Chen X. Expression of high mobility group box chromosomal protein 1 and its modulating effects on downstream cytokines in systemic lupus erythematosus. J Rheumatol. 2010 ; 37: 766-775
11. Dumitriu IE, Baruah P, Bianchi ME, Manfredi AA, Rovere-Querini P. Requirement of HMGB1 and RAGE for the maturation of human plasmacytoid dendritic cells. Eur J Immunol. 2005 ; 35: 2184-2190
12. Liu QY, Yao YM, Yan YH, Dong N, Sheng ZY. High mobility group box 1 protein suppresses T cell-mediated immunity via CD11c(low)CD45RB(high) dendritic cell differentiation. Cytokine. 2011 ; 54: 205-211
13. Kadowaki N, Antonenko S, Liu YJ. Distinct CpG DNA and polyinosinic-polycytidylic acid double-stranded RNA, respectively, stimulate CD11c2 type 2 dendritic cell precursors and CD11c+ dendritic cells to produce type I IFN. J Immunol. 2001 ; 166: 2291-2295
14. Theophilopoulos AN, Baccala R, Beutler B, Kono DH. Type 1 interferons (alpha/beta) in immunity and autoimmunity. Annual Rev Immunol. 2005 ; 23: 307-335
15. Banchereau J, Pascual V. Type I interferon in systemic lupus erythematosus and other autoimmune diseases. Immunity. 2006 ; 25: 383-392
16. Obermoser G, Pascual V. The interferon-α signature of systemic lupus erythematosus. Lupus. 2010 ; 19: 1012-1019
17. Clark DN, Poole BD. Interferon and apoptosis in systemic lupus erythematosus. In: Almoallim H (ed.) Systemic lupus erythematosus. 2012, ISBN: 978-953-51-0266-3, InTech, http://www.intechopen.com/books/systemic-lupus- erythematosus/interferon-in-systemic-lupus-erythematosus (2013, accessed).
18. Bonaccorsi I, Cantoni C, Carrega P, et al. The immune inhibitory receptor LAIR-1 is highly expressed by plasmatocytoid dendritic cells and acts complementary with NKp44 to control IFNa production. PLoS One. 2010 ; 5: e15080 - e15080
19. Griffiths B. Assessment of patients with systemic lupus erythematosus and the use of lupus disease activity indices. Best Pract Res Clin Rheumatol. 2005 ; 19: 685-708
20. Jiang W, Pisetsky DS. Expression of high mobility group protein 1 in the sera of patients and mice with systemic lupus erythematosus. Ann Rheum Dis. 2008 ; 67: 727-728
21. Abdulahad DA, Westra J, Bijzert J, Limburg PC, Kallenberg CG, Bijl M. High mobility group box 1 (HMGB1) and anti-HMGB1 antibodies and their relation to disease characteristics in systemic lupus erythematosus. Arthritis Res Ther. 2011 ; 13: R71 - R71
22. Ma CY, Jiao YL, Zhang J, et al. Elevated plasma level of HMGB1 is associated with disease activity and combined alterations with IFN-alpha and TNF-alpha in systemic lupus erythematosus. Rheumatol Int. 2012 ; 32: 395-402
23. Zickert A, Palmblad K, Sundelin B, et al. Renal expression and serum levels of high mobility group box 1 protein in lupus nephritis. Arthritis Res Ther. 2012 ; 14: R36 - R36
24. Abdulahad DA, Westra J, Bijzet J, et al. Urine levels of HMGB 1 in systemic lupus erythematosus patients with and without renal manifestations. Arthritis Res Ther. 2012 ; 14: R184 - R184
25. Wen Z, Xu L, Chen X, et al. Autoantibody induction by DNA-containing immune complexes requires HMGB1 with the TLR2/microRNA-155 pathway. J Immunol. 2013 ; 190: 5411-5422
26. Liu G, Wang J, Park YJ, et al. High mobility group protein-inhibits phagocytosis of apoptotic neutrophils through binding to phosphatidylserine. J Immunol. 2008 ; 181: 4240-4246
27. Niewold TB, Hua J, Lehman TJ, Harley JB, Crow MK. High serum IFN-alpha activity is a heritable risk factor for systemic lupus erythematosus. Genes Immun. 2007 ; 8: 492-502
28. Gota C, Calabrese L. Induction of clinical autoimmune disease by therapeutic interferon-alpha. Autoimmunity. 2003 ; 36: 511-518
29. Fanning SL, George TC, Feng D, et al. Receptor cross-linking on human plasmacytoid dendritic cells leads to the regulation of IFN-alpha production. J Immunol. 2006 ; 177: 5829-5839
30. Meyaard L. The inhibitory collagen receptor LAIR1 (CD305). J Leukoc Biol. 2008 ; 83: 799-803
31. Colombo B, Canevali P, Magnani O, et al. Defective expression and function of the leukocyte associated Ig-like receptor 1 in B lymphocytes from systemic lupus erythematosus patients. PloS One. 2012 ; 7: e31903 - e31903