Advanced glycation end products activate the miRNA/RhoA/ROCK2 pathway in endothelial cells

Microcirculation

Volumn 21, Issue 2, 2014, Pages 178-186

  Wu, Xiao dan ^a   Liu, Wei lin ^b   Zeng, Kai ^c   Lei, Hong yi ^a   Zhang, Qing guo ^a   Zhou, Shu qin ^a   Xu, Shi yuan ^a  

^a SOUTHERN MEDICAL UNIVERSITY   (China)

^b FUJIAN UNIVERSITY OF TRADITIONAL CHINESE MEDICINE   (China)

^c FUJIAN MEDICAL UNIVERSITY   (China)

Author keywords

Advanced glycation end products; F actin; Monolayer permeability; Reactive oxygen species; RhoA ROCK

Indexed keywords

ADVANCED GLYCATION END PRODUCT; MICRORNA; MIRN200 MICRORNA, HUMAN; RHO KINASE; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; RHOA PROTEIN, HUMAN; ROCK2 PROTEIN, HUMAN;

APOPTOSIS; CAPILLARY PERMEABILITY; DRUG EFFECTS; HUMAN; METABOLISM; PATHOLOGY; UMBILICAL VEIN ENDOTHELIAL CELL;

APOPTOSIS; CAPILLARY PERMEABILITY; GLYCOSYLATION END PRODUCTS, ADVANCED; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; MICRORNAS; RHO-ASSOCIATED KINASES; RHOA GTP-BINDING PROTEIN;

EID: 84894031118     PISSN: 10739688     EISSN: 15498719     Source Type: Journal    
DOI: 10.1111/micc.12104     Document Type: Article

References (43)

1. Basta G, Schmidt AM, De Caterina R. Advanced glycation end products and vascular inflammation: implications for accelerated atherosclerosis in diabetes. Cardiovasc Res 63: 582-592, 2004.
2. Bolognin S, Zatta P, Lorenzetto E, Valenti MT, Buffelli M. beta-Amyloid-aluminum complex alters cytoskeletal stability and increases ROS production in cortical neurons. Neurochem Int 62: 566-574, 2013.
3. Bryan BA, Dennstedt E, Mitchell DC, Walshe TE, Noma K, Loureiro R, Saint-Geniez M, Campaigniac JP, Liao JK, D'Amore PA. RhoA/ROCK signaling is essential for multiple aspects of VEGF-mediated angiogenesis. FASEB J 24: 3186-3195, 2010.
4. Cao H, Jiang Y, Wang Y. Stereospecific synthesis and characterization of oligodeoxyribonucleotides containing an N2-(1-carboxyethyl)-2'-deoxyguanosine. J Am Chem Soc 129: 12123-12130, 2007.
5. Choi YC, Yoon S, Jeong Y, Yoon J, Baek K. Regulation of vascular endothelial growth factor signaling by miR-200b. Mol Cells 32: 77-82, 2011.
6. Droge W. Free radicals in the physiological control of cell function. Physiol Rev 82: 47-95, 2002.
7. Enomoto M, Adachi H, Yamagishi S, Takeuchi M, Furuki K, Hino A, Hiratsuka A, Takajo Y, Imaizumi T. Positive association of serum levels of advanced glycation end products with thrombogenic markers in humans. Metabolism 55: 912-917, 2006.
8. Felli N, Fontana L, Pelosi E, Botta R, Bonci D, Facchiano F, Liuzzi F, Lulli V, Morsilli O, Santoro S, Valtieri M, Calin GA, Liu CG, Sorrentino A, Croce CM, Peschle C. MicroRNAs 221 and 222 inhibit normal erythropoiesis and erythroleukemic cell growth via kit receptor down-modulation. Proc Natl Acad Sci U S A 102: 18081-18086, 2005.
9. Fish JE. A primer on the role of microRNAs in endothelial biology and vascular disease. Semin Nephrol 32: 167-175, 2012.
10. Fish JE, Cybulsky MI. Taming endothelial activation with a microRNA. J Clin Invest 122: 1967-1970, 2012.
11. Fraser PA. The role of free radical generation in increasing cerebrovascular permeability. Free Radic Biol Med 51: 967-977, 2011.
12. Gao C, Li R, Liu Y, Ma L, Wang S. Rho-kinase-dependent F-actin rearrangement is involved in the release of endothelial microparticles during IFN-alpha-induced endothelial cell apoptosis. J Trauma Acute Care Surg 73: 1152-1160, 2012.
13. Guo XH, Huang QB, Chen B, Wang SY, Li Q, Zhu YJ, Hou FF, Fu N, Brunk UT, Zhao M. Advanced glycation end products induce actin rearrangement and subsequent hyperpermeability of endothelial cells. APMIS 114: 874-883, 2006.
14. Harris TA, Yamakuchi M, Ferlito M, Mendell JT, Lowenstein CJ. MicroRNA-126 regulates endothelial expression of vascular cell adhesion molecule 1. Proc Natl Acad Sci U S A 105: 1516-1521, 2008.
15. Harris TA, Yamakuchi M, Kondo M, Oettgen P, Lowenstein CJ. Ets-1 and Ets-2 regulate the expression of microRNA-126 in endothelial cells. Arterioscler Thromb Vasc Biol 30: 1990-1997, 2010.
16. He L, He X, Lowe SW, Hannon GJ. microRNAs join the p53 network-another piece in the tumour-suppression puzzle. Nat Rev Cancer 7: 819-822, 2007.
17. Hernandez-Covarrubias C, Vilchis-Reyes MA, Yepez-Mulia L, Sanchez-Diaz R, Navarrete-Vazquez G, Hernandez-Campos A, Castillo R, Hernandez-Luis F. Exploring the interplay of physicochemical properties, membrane permeability and giardicidal activity of some benzimidazole derivatives. Eur J Med Chem 52: 193-204, 2012.
18. Horiuchi S, Araki N, Morino Y. Immunochemical approach to characterize advanced glycation end products of the Maillard reaction. Evidence for the presence of a common structure. J Biol Chem 266: 7329-7332, 1991.
19. Kang R, Tang D, Schapiro NE, Livesey KM, Farkas A, Loughran P, Bierhaus A, Lotze MT, Zeh HJ. The receptor for advanced glycation end products (RAGE) sustains autophagy and limits apoptosis, promoting pancreatic tumor cell survival. Cell Death Differ 17: 666-676, 2010.
20. Li LM, Hou DX, Guo YL, Yang JW, Liu Y, Zhang CY, Zen K. Role of microRNA-214-targeting phosphatase and tensin homolog in advanced glycation end product-induced apoptosis delay in monocytes. J Immunol 186: 2552-2560, 2011.
21. Lyu J, Hu Y, Xu X, Zhang H. Dynamics of focal adhesions and reorganization of F-actin in VEGF-stimulated NSCs under varying differentiation states. J Cell Biochem 114: 1744-1759, 2013.
22. Madamanchi NR, Vendrov A, Runge MS. Oxidative stress and vascular disease. Arterioscler Thromb Vasc Biol 25: 29-38, 2005.
23. Magenta A, Cencioni C, Fasanaro P, Zaccagnini G, Greco S, Sarra-Ferraris G, Antonini A, Martelli F, Capogrossi MC. miR-200c is upregulated by oxidative stress and induces endothelial cell apoptosis and senescence via ZEB1 inhibition. Cell Death Differ 18: 1628-1639, 2011.
24. Montezano AC, Touyz RM. Reactive oxygen species and endothelial function-role of nitric oxide synthase uncoupling and Nox family nicotinamide adenine dinucleotide phosphate oxidases. Basic Clin Pharmacol Toxicol 110: 87-94, 2012.
25. Morita M, Yano S, Yamaguchi T, Sugimoto T. Advanced glycation end products-induced reactive oxygen species generation is partly through NF-kappa B activation in human aortic endothelial cells. J Diabetes Complications 27: 11-15, 2013.
26. Niiya Y, Abumiya T, Yamagishi S, Takino J, Takeuchi M. Advanced glycation end products increase permeability of brain microvascular endothelial cells through reactive oxygen species-induced vascular endothelial growth factor expression. J Stroke Cerebrovasc Dis 21: 293-298, 2012.
27. Picchi A, Gao X, Belmadani S, Potter BJ, Focardi M, Chilian WM, Zhang C. Tumor necrosis factor-alpha induces endothelial dysfunction in the prediabetic metabolic syndrome. Circ Res 99: 69-77, 2006.
28. Pottiez G, Duban-Deweer S, Deracinois B, Gosselet F, Camoin L, Hachani J, Couraud PO, Cecchelli R, Dehouck MP, Fenart L, Karamanos Y, Flahaut C. A differential proteomic approach identifies structural and functional components that contribute to the differentiation of brain capillary endothelial cells. J Proteomics 75: 628-641, 2011.
29. Sadik NA, Mohamed WA, Ahmed MI. The association of receptor of advanced glycated end products and inflammatory mediators contributes to endothelial dysfunction in a prospective study of acute kidney injury patients with sepsis. Mol Cell Biochem 359: 73-81, 2012.
30. Shatanawi A, Romero MJ, Iddings JA, Chandra S, Umapathy NS, Verin AD, Caldwell RB, Caldwell RW. Angiotensin II-induced vascular endothelial dysfunction through RhoA/Rho kinase/p38 mitogen-activated protein kinase/arginase pathway. Am J Physiol Cell Physiol 300: C1181-C1192, 2011.
31. Siomi MC, Sato K, Pezic D, Aravin AA. PIWI-interacting small RNAs: the vanguard of genome defence. Nat Rev Mol Cell Biol 12: 246-258, 2011.
32. Syngle A, Vohra K, Garg N, Kaur L, Chand P. Advanced glycation end-products inhibition improves endothelial dysfunction in rheumatoid arthritis. Int J Rheum Dis 15: 45-55, 2012.
33. Tanaka N, Yonekura H, Yamagishi S, Fujimori H, Yamamoto Y, Yamamoto H. The receptor for advanced glycation end products is induced by the glycation products themselves and tumor necrosis factor-alpha through nuclear factor-kappa B, and by 17beta-estradiol through Sp-1 in human vascular endothelial cells. J Biol Chem 275: 25781-25790, 2000.
34. Urbich C, Kuehbacher A, Dimmeler S. Role of microRNAs in vascular diseases, inflammation, and angiogenesis. Cardiovasc Res 79: 581-588, 2008.
35. van Nieuw Amerongen GP, Koolwijk P, Versteilen A, van Hinsbergh VW. Involvement of RhoA/Rho kinase signaling in VEGF-induced endothelial cell migration and angiogenesis in vitro. Arterioscler Thromb Vasc Biol 23: 211-217, 2003.
36. Wang S, Huang Q, Guo X, Brunk UT, Han J, Zhao K, Zhao M. The P38alpha and P38delta MAP kinases may be gene therapy targets in the future treatment of severe burns. Shock 34: 176-182, 2010.
37. Wang L, Li S, Jungalwala FB. Receptor for advanced glycation end products (RAGE) mediates neuronal differentiation and neurite outgrowth. J Neurosci Res 86: 1254-1266, 2008.
38. Wang SS, Xu YH, Feng L, Zhu Q, He B. A PKC-beta inhibitor prompts the HUVECs apoptosis-induced by advanced glycation end products. Pharmazie 66: 881-887, 2011.
39. Weber M, Baker MB, Moore JP, Searles CD. MiR-21 is induced in endothelial cells by shear stress and modulates apoptosis and eNOS activity. Biochem Biophys Res Commun 393: 643-648, 2010.
40. Wójciak-Stothard B, Potempa S, Eichholtz T, Ridley AJ. Rho and Rac but not Cdc42 regulate endothelial cell permeability. J Cell Sci 114: 1343-1355, 2001.
41. Wu F, Yang Z, Li G. Role of specific microRNAs for endothelial function and angiogenesis. Biochem Biophys Res Commun 386: 549-553, 2009.
42. Zhao Y, Srivastava D. A developmental view of microRNA function. Trends Biochem Sci 32: 189-197, 2007.
43. Zhou YJ, Wang JH, Zhang J. Hepatocyte growth factor protects human endothelial cells against advanced glycation end products-induced apoptosis. Biochem Biophys Res Commun 344: 658-666, 2006.