Telomere length and telomerase reverse transcriptase mRNA expression in patients with hepatitis C

Hepato-Gastroenterology

Volumn 60, Issue 127, 2013, Pages 1713-1716

  Biron Shental, Tal ^a,b   Amiel, Aliza ^a,c   Anchidin, Ramona ^a,b   Sharony, Reuven ^a,b   Hadary, Ruth ^a,b   Kitay Cohen, Yona ^a,b  

^a MEIR MEDICAL CENTER   (Israel)

^b TEL AVIV UNIVERSITY   (Israel)

^c BAR ILAN UNIVERSITY   (Israel)

Author keywords

HCV; Telomerase reverse transcriptase; Telomeres

Indexed keywords

ADULT; ANTIVIRAL AGENTS; CASE-CONTROL STUDIES; CELLS, CULTURED; DISEASE PROGRESSION; HEPATITIS C, CHRONIC; HUMANS; IN SITU HYBRIDIZATION, FLUORESCENCE; LYMPHOCYTES; MIDDLE AGED; REMISSION INDUCTION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TELOMERASE; TELOMERE SHORTENING; TREATMENT OUTCOME;

EID: 84893932566     PISSN: 01726390     EISSN: None     Source Type: Journal    
DOI: 10.5754/hge11165     Document Type: Article

References (29)

1. Harley CB, Futcher AB, Greider CW: Telomeres shorten during aging of human fibroblasts. Nature 1990; 345:458-460.
2. Allsopp RC, Vaziri H, Patterson C, et al.: Telomere length predicts replicative capacity of human fibroblasts. PNAS USA 1992; 89:10114-10118.
3. Counter CM, Avilion AA, LeFeuvre CE, et al.: Telomere shortening associated with chromosome instability is arrested in immortal cells which express telomerase activity. EMBO J 1992; 11:1921-1929.
4. Blasco MA, Lee HW, Hande MP, et al.: Telomere shortening and tumor formation by mouse cells lacking telomerase. RNA 1997; 91:25-34. (Pubitemid 27431310)
5. Rudolph KL, Chang S, Lee HW, et al.: Longevity, stress response and cancer in aging telomerase-deficient mice. Cell 1999; 96:701-712. (Pubitemid 29122812)
6. Pathak S, Multani AS: Aneuploidy, stem cells and cancer. EXS 2006; 96:49-64.
7. Hug N, Lingner J: Telomere length homeostasis. Chromosoma 2006; 115:413-425. (Pubitemid 44642634)
8. Volpi A, Bravaccini S, Medri L, Cerasoli S, Gaudio M, Amadori D: Usefulness of immunological detection of the human telomerase reverse transcriptase. Cellular Oncol 2005; 27:347-353.
9. Kim NW, Piatyszek MA, Prowse KR, et al.: Specific association of human telomerase activity with immortal cells and cancer. Science 1994; 266:2011-2015.
10. Erlitzki R, Minuk GY: Telomeres, telomerase and HCC: the long and the short of it. J Hepatology 1999; 31:939-945. (Pubitemid 29514230)
11. Greider CW: Telomeres, telomerase and senescence. Bioessays 1990; 12:363-369.
12. Greider CW: Mammalian telomere dynamics: healing, fragmentation shortening and stabilization. Curr Op Gen Develop 1994; 4:203-211.
13. Coleman WB: Mechanisms of human hepatocarcinogenesis. Current Molec Med 2003; 3:573e88.
14. Turner NC, Dusheiko G, Jones A: Hepatitis C and B-cell lymphoma. Ann Oncol 2003; 14(9):1341-1345. (Pubitemid 37185279)
15. Fabarius A, Willer A, Yerganian G, Hehlmann R, Duesberg P: Specific aneusomies in Chinese hamster cells at different stages of neoplastic transformation, initiated by nitrosomethylurea. PNAS USA 2002; 99:6778-6783. (Pubitemid 34526208)
16. Kitay-Cohen Y, Goldberg-Bittman L, Hadary R, Fejgin DM, Amiel A: Telomere length in Hepatitis C. Cancer Genet Cytogenet 2008; 187:34-38.
17. Sekoguchi S, Nakajima T, Moriguchi M, et al.: Role of cell-cycle turnover and oxidative stress in telomere shortening and cellular senescence in patients with chronic hepatitis Can J Gastroent Hepat 2007; 22:82-90.
18. Mise K, Tashiro S, Yogita S, et al.: Assessment of the biological malignancy of hepatocellular carcinoma: relationship to clinico-pathological factors and prognosis. Clinics in Cancer Research 1998; 4:1475-1482. (Pubitemid 28265231)
19. Amiel A, Yukla M, Gaber E, Josef G, Fejgin M, Lishner M: Random aneuploidy in CML patients treated with imatinib. Cancer Gen Cytogen 2006; 168:120-123.
20. Chuang TCY, Moshir S, Garini Y, et al.: The three-dimensional organization of telomeres in the nucleus of mammalian cells. BMC Biology 2004; 2:1-8.
21. Vermolen BJ, Garini Y, Young IT, Dirks RW, Raz V: Segmentation and analysis of the three-dimensional redistribution of nuclear components in human mesenchymal stem cell. Cytometry 2008; 73:816-824.
22. Livak KJ, Schmittgen TD: Analysis of relative gene expression data using real-time quantitative PCR and the 2-DDCT method. Methods 2001; 25:402-408. (Pubitemid 34164012)
23. Lossos IS, Czerwinski DK, Wechser MA, Levy R: Optimization of quantitative real-time RT-PCR parameters for the study of lymphoid malignancies. Leukemia 2003; 17:789-795. (Pubitemid 36519378)
24. Satra M, Dalekos GN, Kollia P, Vamvakopoulos N, Tsezou A: Telomerase reverse transcriptase mRNA expression in peripheral lymphocytes of patients with chronic HBV and HCV infections. J Viral Hep 2005; 2:488-493. (Pubitemid 41224252)
25. Horikawa I, Barrett JC: Transcriptional regulation of the telomerase hTER gene as a target for cellular and viral oncogenic mechanisms. Carcinogenesis 2003; 24:1167-1176. (Pubitemid 36927056)
26. Bellon M, Nicot C: Regulation of telomerase and telomeres: Human Tumor Viruses Take Control. J Nat Cancer Inst 2008; 100:98-109.
27. Tillman HL, Manns MP, Rudolph KL: Merging models of hepatitis C virus pathogenesis. Semin Liver Dis 2005; 25:84-92.
28. Miura N, Horikawa I, Nishimoto A, et al.: Progressive telomere shortening and telomerase reactivation during hepatocellular carcinogenesis. Cancer Gen Cytogen 1997; 93:56-62. (Pubitemid 27102490)
29. Bellon M, Datta A, Brown M, et al.: Increased expression of telomere length regulation factors TRF1, TRF2 and TIN2 in patients with adult T-cell leukaemia. International J Cancer 2006; 119:2090-2097. (Pubitemid 44423666)