In vitro evidence that an aqueous extract of centella asiatica modulates α-Synuclein aggregation dynamics

Journal of Alzheimer's Disease

Volumn 39, Issue 2, 2014, Pages 457-465

  Berrocal, Ruben ^a,b   Vasudevaraju, Padmaraju ^a   Indi, Shantinath Satappa ^c   Sambasiva Rao, Krothapalli Raja Surya ^a,b   Rao, K S ^a  

^a INSTITUTO DE INVESTIGACIONES CIENTÍFICAS Y SERVICIOS DE ALTA TECNOLOGÍA   (Panama)

^b ACHARYA NAGARJUNA UNIVERSITY   (India)

^c INDIAN INSTITUTE OF SCIENCE   (India)

Author keywords

anti aggregation; Centella asiatica; circular dichroism; natural products; Parkinson's disease; transmission electron microscopy; Synuclein

Indexed keywords

ALPHA SYNUCLEIN; ASIATIC ACID; CAFFEIC ACID; CENTELLA ASIATICA EXTRACT; CHLOROGENIC ACID; FERULIC ACID; GALLIC ACID; GENTISIC ACID; OLIGOMER; PARA COUMARIC ACID; POLYPHENOL; PROTOCATECHUIC ACID; SELENIUM; THIOFLAVINE;

ARTICLE; BETA SHEET; CIRCULAR DICHROISM; CONTROLLED STUDY; DRUG ACTIVITY; FLUORESCENCE; IN VITRO STUDY; PLANT LEAF; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN CONFORMATION; TRANSMISSION ELECTRON MICROSCOPY;

ANTI-AGGREGATION; CENTELLA ASIATICA; CIRCULAR DICHROISM; NATURAL PRODUCTS; PARKINSON'S DISEASE; TRANSMISSION ELECTRON MICROSCOPY; Α-SYNUCLEIN;

ALPHA-SYNUCLEIN; ANTIPARKINSON AGENTS; CIRCULAR DICHROISM; ELECTROPHORESIS, POLYACRYLAMIDE GEL; FLUORESCENCE; KINETICS; MICROSCOPY, ELECTRON, TRANSMISSION; PLANT EXTRACTS; POLYPHENOLS; PROTEIN MULTIMERIZATION; THIAZOLES; TRITERPENES; WATER;

EID: 84893908949     PISSN: 13872877     EISSN: 18758908     Source Type: Journal    
DOI: 10.3233/JAD-131187     Document Type: Article

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