Oral immunization with whole yeast producing viral capsid antigen provokes a stronger humoral immune response than purified viral capsid antigen

Letters in Applied Microbiology

Volumn 58, Issue 3, 2014, Pages 285-291

  Kim, H J ^a,a   Lee, J Y ^a   Kang, H A ^a   Lee, Y ^b   Park, E J ^b  

^a Chung Ang University   (South Korea)

^b Migun Techno World   (South Korea)

Author keywords

Capsid protein; Nodavirus; Saccharomyces cerevisiae; Vaccine

Indexed keywords

ANTIBODIES; IMMUNIZATION; MAMMALS; PURIFICATION; RECOMBINANT PROTEINS; VACCINES; VIRUSES; YEAST;

ANTIBODIES RESPONSE; CAPSID PROTEINS; CELL-BE; CELL/B.E; CELL/BE; HUMORAL IMMUNE RESPONSE; NODAVIRUS; PROTEIN ANTIGENS; RECOMBINANT YEAST; VIRAL CAPSIDS;

ANTIGENS;

CAPSID PROTEIN; IMMUNOGLOBULIN G; RECOMBINANT ANTIGEN; VIRUS CAPSID ANTIGEN;

ANTIBODY; ANTIGEN; IMMUNE RESPONSE; IMMUNIZATION; PROTEIN; VACCINE; YEAST;

ANIMAL EXPERIMENT; ANTIBODY RESPONSE; ANTIGEN SPECIFICITY; ARTICLE; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; HOST; HUMORAL IMMUNITY; IMMUNE RESPONSE; IMMUNIZATION; IMMUNOGLOBULIN BLOOD LEVEL; MOUSE; NONHUMAN; SACCHAROMYCES CEREVISIAE; SERUM; VIRUS PURIFICATION; YEAST;

EPINEPHELUS ANALOGUS; MIRIDAE; MUS; NODAVIRIDAE; REDSPOTTED GROUPER NERVOUS NECROSIS VIRUS; SACCHAROMYCES CEREVISIAE;

CAPSID PROTEIN; NODAVIRUS; SACCHAROMYCES CEREVISIAE; VACCINE;

ANIMALS; ANTIBODIES, VIRAL; ANTIGENS, VIRAL; CAPSID PROTEINS; CELL LINE; FEMALE; GENE EXPRESSION; IMMUNITY, HUMORAL; IMMUNIZATION; MICE; MICE, INBRED BALB C; NODAVIRIDAE; SACCHAROMYCES CEREVISIAE;

EID: 84893869892     PISSN: 02668254     EISSN: 1472765X     Source Type: Journal    
DOI: 10.1111/lam.12188     Document Type: Article

References (31)

1. Chavali, S.R., Barton, L.D. and Campbell, J.B. (1988) Immunopotentiation by orally-administered Quillaja saponins: effects in mice vaccinated intraperitoneally against rabies. Clin Exp Immunol 74, 339-343.
2. Choi, Y.R., Kim, H.J., Lee, J.Y., Kang, H.A. and Kim, H.-J. (2013) Chromatographically-purified capsid proteins of red-spotted grouper nervous necrosis virus expressed in Saccharomyces cerevisiae form virus-like particles. Protein Expres Purif 89, 162-168.
3. Deakin, J.E., Papenfuss, A.T., Belov, K., Cross, J.G.R., Coggill, P., Palmer, S., Sims, S., Speed, T.P. et al. (2006) Evolution and comparative analysis of the MHC Class III inflammatory region. BMC Genomics 7, doi:10.1186/1471-2164-7-281.
4. Devriendt, B., De Geest, B.G., Goddeeris, B.M. and Cox, E. (2012) Crossing the barrier: targeting epithelial receptors for enhanced oral vaccine delivery. J Control Release 160, 431-439.
5. El-Boshy, M.E., El-Ashram, A.M., Abdelhamid, F.M. and Gadalla, H.A. (2010) Immunomodulatory effect of dietary Saccharomyces cerevisiae, beta-glucan and laminaran in mercuric chloride treated Nile tilapia (Oreochromis niloticus) and experimentally infected with Aeromonas hydrophila. Fish Shellfish Immunol 28, 802-808.
6. Finnis, C.J., Payne, T., Hay, J., Dodsworth, N., Wilkinson, D., Morton, P., Saxton, M.J., Tooth, D.J. et al. (2010) High-level production of animal-free recombinant transferrin from Saccharomyces cerevisiae. Microb Cell Fact 9, doi:10.1186/1475-2859-9-87.
7. Food and Drug Administration, U.S. (2001) Partial List Of Microorganisms And Microbial-Derived Ingredients That Are Used In Foods. http://www.fda.gov/Food/IngredientsPackagingLabeling/GRAS/MicroorganismsMicrobialDerivedIngredients/default.htm. (Accessed 21 August 2013).
8. Graff, S., Chaumeil, J.C., Boy, P., Lai-Kuen, R. and Charrueau, C. (2008) Influence of pH conditions on the viability of Saccharomyces boulardii yeast. J Gen Appl Microbiol 54, 221-227.
9. Grotmol, S., Totland, G.K. and Kryvi, H. (1997) Detection of a nodavirus-like agent in heart tissue from reared Atlantic salmon Salmo salar suffering from cardiac myopathy syndrome (CMS). Dis Aquat Organ 29, 79-84.
10. Lee, J.Y., Xu, M.L., Kim, H.J., Kang, H.A. and Kim, H.-J. (2013) A comparative study of the adjuvanticity of Hansenula polymorpha, Saccharomyces cerevisiae and Yarrowia lipolytica in oral and nasal immunization with virus capsid antigens. Biotechnol Lett 35, 1881-1888.
11. Liu, W.T., Hsu, C.H., Chang, C.Y., Chen, H.H. and Lin, C.S. (2006) Immune response against grouper nervous necrosis virus by vaccination of virus-like particles. Vaccine 24, 6282-6287.
12. Mach, H., Volkin, D.B., Troutman, R.D., Wang, B., Luo, Z., Jansen, K.U. and Shi, L. (2006) Disassembly and reassembly of yeast-derived recombinant human papillomavirus virus-like particles (HPV VLPs). J Pharm Sci 95, 2195-2206.
13. Mestecky, J., Russell, M.W. and Elson, C.O. (2007) Perspectives on mucosal vaccines: is mucosal tolerance a barrier? J Immunol 179, 5633-5638.
14. Munday, B.L. and Nakai, T. (1997) Nodaviruses as pathogens in larval and juvenile marine finfish. World J Microbiol Biotechnol 13, 375-381.
15. Murtaugh, M.P. and Foss, D.L. (2002) Inflammatory cytokines and antigen presenting cell activation. Vet Immunol Immunopathol 87, 109-121.
16. Pickering, R.J., Smith, S.D., Strugnell, R.A., Wesselingh, S.L. and Webster, D.E. (2006) Crude saponins improve the immune response to an oral plant-made measles vaccine. Vaccine 24, 144-150.
17. Plant, K.P. and LaPatra, S.E. (2011) Advances in fish vaccine delivery. Dev Comp Immunol 35, 1256-1262.
18. Pucci, B., Coscia, M.R. and Oreste, U. (2003) Characterization of serum immunoglobulin M of the Antarctic teleost Trematomus bernacchii. Comp Biochem Physiol B Biochem Mol Biol 135, 349-357.
19. Rombout, J.H.W.M., Taverne, N., Vandekamp, M. and Tavernethiele, A.J. (1993) Differences in mucus and serum immunoglobulin of carp (Cyprinus-Carpio L). Dev Comp Immunol 17, 309-317.
20. Salnur, S., Gultepe, N. and Hossu, B. (2009) Replacement of fish meal by yeast (Saccharomyces cerevisiae): effects on digestibility and blood parameters for gilthead sea bream (Sparus aurata). J Anim Vet Adv 8, 2557-2561.
21. Schneemann, A. and Marshall, D. (1998) Specific encapsidation of nodavirus RNAs is mediated through the C terminus of capsid precursor protein alpha. J Virol 72, 8738-8746.
22. Shieh, J.R. and Chi, S.C. (2005) Production of monoclonal antibodies against grouper nervous necrosis virus (GNNV) and development of an antigen capture ELISA. Dis Aquat Organ 63, 53-60.
23. Skliris, G.P., Krondiris, J.V., Sideris, D.C., Shinn, A.P., Starkey, W.G. and Richards, R.H. (2001) Phylogenetic and antigenic characterization of new fish nodavirus isolates from Europe and Asia. Virus Res 75, 59-67.
24. Sultmann, H., Mayer, W.E., Figueroa, F., Ohuigin, C. and Klein, J. (1993) Zebrafish Mhc Class-Ii Alpha-Chain-Encoding Genes - Polymorphism, Expression, and Function. Immunogenetics 38, 408-420.
25. Sunyer, J.O. (2013) Fishing for mammalian paradigms in the teleost immune system. Nat Immunol 14, 320-326.
26. Tan, C., Huang, B., Chang, S.F., Ngoh, G.H., Munday, B., Chen, S.C. and Kwang, J. (2001) Determination of the complete nucleotide sequences of RNA1 and RNA2 from greasy grouper (Epinephelus tauvina) nervous necrosis virus, Singapore strain. J Gen Virol 82, 647-653.
27. Thiery, R., Cozien, J., Cabon, J., Lamour, F., Baud, M. and Schneemann, A. (2006) Induction of a protective immune response against viral nervous necrosis in the European sea bass Dicentrarchus labrax by using betanodavirus virus-like particles. J Virol 80, 10201-10207.
28. Thomas, D.S. (1988) Electropositively charged filters for the recovery of yeasts and bacteria from beverages. J Appl Bacteriol 65, 35-41.
29. Thones, N., Herreiner, A., Schadlich, L., Piuko, K. and Muller, M. (2008) A direct comparison of human papillomavirus type 16 L1 particles reveals a lower immunogenicity of capsomeres than viruslike particles with respect to the induced antibody response. J Virol 82, 5472-5485.
30. Uribe, C., Folch, H., Enriquez, R. and Moran, G. (2011) Innate and adaptive immunity in teleost fish: a review. Vet Med 56, 486-503.
31. Xiang, S.D., Scholzen, A., Minigo, G., David, C., Apostolopoulos, V., Mottram, P.L. and Plebanski, M. (2006) Pathogen recognition and development of particulate vaccines: does size matter? Methods 40, 1-9.