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Volumn 9, Issue , 2010, Pages

High-level production of animal-free recombinant transferrin from saccharomyces cerevisiae

Author keywords

[No Author keywords available]

Indexed keywords

ALBUFUSE; HUMAN ALBUMIN; HYBRID PROTEIN; PROTEIN DISULFIDE ISOMERASE; RECOMBINANT PROTEIN; RECOMBUMIN; TRANSFERRIN; UNCLASSIFIED DRUG; CHAPERONE;

EID: 78349281567     PISSN: None     EISSN: 14752859     Source Type: Journal    
DOI: 10.1186/1475-2859-9-87     Document Type: Article
Times cited : (33)

References (37)
  • 1
    • 0036238011 scopus 로고    scopus 로고
    • Transferrin/transferrin receptor-mediated drug delivery
    • 10.1002/med.10008, 11933019
    • Li H, Qian ZM. Transferrin/transferrin receptor-mediated drug delivery. Med Res Rev 2002, 22(3):225-250. 10.1002/med.10008, 11933019.
    • (2002) Med Res Rev , vol.22 , Issue.3 , pp. 225-250
    • Li, H.1    Qian, Z.M.2
  • 2
    • 13544254423 scopus 로고    scopus 로고
    • Transferrin: structure, function and potential therapeutic actions
    • 10.1016/S1359-6446(04)03333-1, 15708745
    • Gomme PT, McCann KB, Bertolini J. Transferrin: structure, function and potential therapeutic actions. Drug Discov Today 2005, 10(4):267-273. 10.1016/S1359-6446(04)03333-1, 15708745.
    • (2005) Drug Discov Today , vol.10 , Issue.4 , pp. 267-273
    • Gomme, P.T.1    McCann, K.B.2    Bertolini, J.3
  • 3
    • 0345943229 scopus 로고    scopus 로고
    • Therapeutic potential of human transferrin and lactoferrin
    • Weinberg ED. Therapeutic potential of human transferrin and lactoferrin. ASM News 2002, 68(2):65-69.
    • (2002) ASM News , vol.68 , Issue.2 , pp. 65-69
    • Weinberg, E.D.1
  • 4
    • 0027360042 scopus 로고
    • Studies on familial hypotransferrinemia: unique clinical course and molecular pathology
    • 1682235, 8317485
    • Hayashi A, Wada Y, Suzuki T, Shimizu A. Studies on familial hypotransferrinemia: unique clinical course and molecular pathology. Am J Hum Genet 1993, 53(1):201-213. 1682235, 8317485.
    • (1993) Am J Hum Genet , vol.53 , Issue.1 , pp. 201-213
    • Hayashi, A.1    Wada, Y.2    Suzuki, T.3    Shimizu, A.4
  • 6
    • 0036439587 scopus 로고    scopus 로고
    • Effective binding of free iron by a single intravenous dose of human apotransferrin in haematological stem cell transplant patients
    • 10.1046/j.1365-2141.2002.03836.x, 12406099
    • Sahlstedt L, von Bonsdorff L, Ebeling F, Ruutu T, Parkkinen J. Effective binding of free iron by a single intravenous dose of human apotransferrin in haematological stem cell transplant patients. Br J Haematol 2002, 119(2):547-553. 10.1046/j.1365-2141.2002.03836.x, 12406099.
    • (2002) Br J Haematol , vol.119 , Issue.2 , pp. 547-553
    • Sahlstedt, L.1    von Bonsdorff, L.2    Ebeling, F.3    Ruutu, T.4    Parkkinen, J.5
  • 7
    • 0034906541 scopus 로고    scopus 로고
    • Development of a pharmaceutical apotransferrin product for iron binding therapy
    • 10.1006/biol.2001.0273, 11482890
    • von Bonsdorff L, Tolo H, Lindeberg E, Nyman T, Harju A, Parkkinen J. Development of a pharmaceutical apotransferrin product for iron binding therapy. Biologicals 2001, 29(1):27-37. 10.1006/biol.2001.0273, 11482890.
    • (2001) Biologicals , vol.29 , Issue.1 , pp. 27-37
    • von Bonsdorff, L.1    Tolo, H.2    Lindeberg, E.3    Nyman, T.4    Harju, A.5    Parkkinen, J.6
  • 8
    • 1642371463 scopus 로고    scopus 로고
    • Reduction of circulating redox-active iron by apotransferrin protects against renal ischemia-reperfusion injury
    • 10.1097/01.TP.0000115002.28575.E7, 15021827
    • de Vries B, Walter SJ, von Bonsdorff L, Wolfs TG, van Heurn LW, Parkkinen J, Buurman WA. Reduction of circulating redox-active iron by apotransferrin protects against renal ischemia-reperfusion injury. Transplantation 2004, 77(5):669-675. 10.1097/01.TP.0000115002.28575.E7, 15021827.
    • (2004) Transplantation , vol.77 , Issue.5 , pp. 669-675
    • de Vries, B.1    Walter, S.J.2    von Bonsdorff, L.3    Wolfs, T.G.4    van Heurn, L.W.5    Parkkinen, J.6    Buurman, W.A.7
  • 9
    • 18844381354 scopus 로고    scopus 로고
    • Recombinant granulocyte colony-stimulating factor-transferrin fusion protein as an oral myelopoietic agent
    • 10.1073/pnas.0500062102, 1129103, 15870205
    • Bai Y, Ann DK, Shen WC. Recombinant granulocyte colony-stimulating factor-transferrin fusion protein as an oral myelopoietic agent. Proc Natl Acad Sci USA 2005, 102(20):7292-7296. 10.1073/pnas.0500062102, 1129103, 15870205.
    • (2005) Proc Natl Acad Sci USA , vol.102 , Issue.20 , pp. 7292-7296
    • Bai, Y.1    Ann, D.K.2    Shen, W.C.3
  • 10
    • 72149095736 scopus 로고    scopus 로고
    • Human growth hormone-transferrin fusion protein for oral delivery in hypophysectomized rats
    • 10.1016/j.jconrel.2009.09.007, 19761807
    • Amet N, Wang W, Shen WC. Human growth hormone-transferrin fusion protein for oral delivery in hypophysectomized rats. J Control Release 2010, 141(2):177-182. 10.1016/j.jconrel.2009.09.007, 19761807.
    • (2010) J Control Release , vol.141 , Issue.2 , pp. 177-182
    • Amet, N.1    Wang, W.2    Shen, W.C.3
  • 11
    • 62149133544 scopus 로고    scopus 로고
    • Fusion-proteins as biopharmaceuticals - applications and challenges
    • Schmidt SR. Fusion-proteins as biopharmaceuticals - applications and challenges. Curr Opin Drug Discov Devel 2009, 12(2):284-295.
    • (2009) Curr Opin Drug Discov Devel , vol.12 , Issue.2 , pp. 284-295
    • Schmidt, S.R.1
  • 12
    • 0035152278 scopus 로고    scopus 로고
    • Carbohydrate-deficient transferrin as a marker of chronic alcohol abuse: a critical review of preanalysis, analysis, and interpretation
    • Arndt T. Carbohydrate-deficient transferrin as a marker of chronic alcohol abuse: a critical review of preanalysis, analysis, and interpretation. Clin Chem 2001, 47(1):13-27.
    • (2001) Clin Chem , vol.47 , Issue.1 , pp. 13-27
    • Arndt, T.1
  • 13
    • 0027173204 scopus 로고
    • Expression of glycosylated and nonglycosylated human transferrin in mammalian cells. Characterization of the recombinant proteins with comparison to three commercially available transferrins
    • 10.1021/bi00071a025, 8499451
    • Mason AB, Miller MK, Funk WD, Banfield DK, Savage KJ, Oliver RW, Green BN, MacGillivray RT, Woodworth RC. Expression of glycosylated and nonglycosylated human transferrin in mammalian cells. Characterization of the recombinant proteins with comparison to three commercially available transferrins. Biochemistry 1993, 32(20):5472-5479. 10.1021/bi00071a025, 8499451.
    • (1993) Biochemistry , vol.32 , Issue.20 , pp. 5472-5479
    • Mason, A.B.1    Miller, M.K.2    Funk, W.D.3    Banfield, D.K.4    Savage, K.J.5    Oliver, R.W.6    Green, B.N.7    MacGillivray, R.T.8    Woodworth, R.C.9
  • 15
    • 77249172664 scopus 로고    scopus 로고
    • Structural and functional characterization of recombinant human serum transferrin secreted from Pichia pastoris
    • 10.1271/bbb.90635, 20139607
    • Mizutani K, Hashimoto K, Takahashi N, Hirose M, Aibara S, Mikami B. Structural and functional characterization of recombinant human serum transferrin secreted from Pichia pastoris. Biosci Biotechnol Biochem 2010, 74(2):309-315. 10.1271/bbb.90635, 20139607.
    • (2010) Biosci Biotechnol Biochem , vol.74 , Issue.2 , pp. 309-315
    • Mizutani, K.1    Hashimoto, K.2    Takahashi, N.3    Hirose, M.4    Aibara, S.5    Mikami, B.6
  • 16
    • 77249099943 scopus 로고    scopus 로고
    • Overexpression of protein disulfide isomerases enhances secretion of recombinant human transferrin in Schizosaccharomyces pombe
    • 10.1007/s00253-009-2393-x, 20013338
    • Mukaiyama H, Tohda H, Takegawa K. Overexpression of protein disulfide isomerases enhances secretion of recombinant human transferrin in Schizosaccharomyces pombe. Appl Microbiol Biotechnol 2010, 86(4):1135-1143. 10.1007/s00253-009-2393-x, 20013338.
    • (2010) Appl Microbiol Biotechnol , vol.86 , Issue.4 , pp. 1135-1143
    • Mukaiyama, H.1    Tohda, H.2    Takegawa, K.3
  • 17
    • 77956668965 scopus 로고    scopus 로고
    • Plant-derived recombinant human serum transferrin demonstrates multiple functions
    • 10.1111/j.1467-7652.2010.00499.x, 20432512
    • Brandsma ME, Diao H, Wang X, Kohalmi SE, Jevnikar AM, Ma S. Plant-derived recombinant human serum transferrin demonstrates multiple functions. Plant Biotechnol J 2010, 8(4):489-505. 10.1111/j.1467-7652.2010.00499.x, 20432512.
    • (2010) Plant Biotechnol J , vol.8 , Issue.4 , pp. 489-505
    • Brandsma, M.E.1    Diao, H.2    Wang, X.3    Kohalmi, S.E.4    Jevnikar, A.M.5    Ma, S.6
  • 18
    • 77957884786 scopus 로고    scopus 로고
    • Expression, purification, and characterization of recombinant human transferrin from rice (Oryza sativa L.)
    • 10.1016/j.pep.2010.04.019, 20447458
    • Zhang D, Nandi S, Bryan P, Pettit S, Nguyen D, Santos MA, Huang N. Expression, purification, and characterization of recombinant human transferrin from rice (Oryza sativa L.). Protein Expr Purif 2010, 74(1):69-79. 10.1016/j.pep.2010.04.019, 20447458.
    • (2010) Protein Expr Purif , vol.74 , Issue.1 , pp. 69-79
    • Zhang, D.1    Nandi, S.2    Bryan, P.3    Pettit, S.4    Nguyen, D.5    Santos, M.A.6    Huang, N.7
  • 20
    • 0035970278 scopus 로고    scopus 로고
    • Yeast 2 micron plasmid copy number is elevated by a mutation in the nuclear gene UBC4
    • 10.1002/yea.679, 11255249
    • Sleep D, Finnis C, Turner A, Evans L. Yeast 2 micron plasmid copy number is elevated by a mutation in the nuclear gene UBC4. Yeast 2001, 18(5):403-421. 10.1002/yea.679, 11255249.
    • (2001) Yeast , vol.18 , Issue.5 , pp. 403-421
    • Sleep, D.1    Finnis, C.2    Turner, A.3    Evans, L.4
  • 21
    • 0032579311 scopus 로고    scopus 로고
    • Disruption of the Saccharomyces cerevisiae YAP3 gene reduces the proteolytic degradation of secreted recombinant human albumin
    • 10.1002/(SICI)1097-0061(19980130)14:2<161::AID-YEA208>3.0.CO;2-Y, 9483804
    • Kerry-Williams SM, Gilbert SC, Evans LR, Ballance DJ. Disruption of the Saccharomyces cerevisiae YAP3 gene reduces the proteolytic degradation of secreted recombinant human albumin. Yeast 1998, 14(2):161-169. 10.1002/(SICI)1097-0061(19980130)14:2<161::AID-YEA208>3.0.CO;2-Y, 9483804.
    • (1998) Yeast , vol.14 , Issue.2 , pp. 161-169
    • Kerry-Williams, S.M.1    Gilbert, S.C.2    Evans, L.R.3    Ballance, D.J.4
  • 22
    • 34249036297 scopus 로고    scopus 로고
    • Enhanced protein expression through strain selection, gene disruption, improved vector design and co-expression of endogenous chaperones
    • Sleep D, Finnis C, Evans L. Enhanced protein expression through strain selection, gene disruption, improved vector design and co-expression of endogenous chaperones. Microb Cell Fact 2006, 5(Suppl 1):S29.
    • (2006) Microb Cell Fact , vol.5 , Issue.SUPPL. 1
    • Sleep, D.1    Finnis, C.2    Evans, L.3
  • 23
    • 0024451883 scopus 로고
    • A novel class of vector for yeast transformation
    • 10.1007/BF00411079, 2676207
    • Chinery SA, Hinchliffe E. A novel class of vector for yeast transformation. Curr Genet 1989, 16(1):21-25. 10.1007/BF00411079, 2676207.
    • (1989) Curr Genet , vol.16 , Issue.1 , pp. 21-25
    • Chinery, S.A.1    Hinchliffe, E.2
  • 24
    • 0028219869 scopus 로고
    • Protein disulfide isomerase overexpression increases secretion of foreign proteins in Saccharomyces cerevisiae
    • 10.1038/nbt0494-381, 7764684
    • Robinson AS, Hines V, Wittrup KD. Protein disulfide isomerase overexpression increases secretion of foreign proteins in Saccharomyces cerevisiae. Biotechnology (N Y) 1994, 12(4):381-384. 10.1038/nbt0494-381, 7764684.
    • (1994) Biotechnology (N Y) , vol.12 , Issue.4 , pp. 381-384
    • Robinson, A.S.1    Hines, V.2    Wittrup, K.D.3
  • 26
    • 33748103344 scopus 로고    scopus 로고
    • Evaluation of recombinant human transferrin (DeltaFerrin™) as an iron chelator in serum-free media for mammalian cell culture
    • 10.1007/s10616-006-9011-x, 19002892
    • Keenan J, Pearson D, O'Driscoll L, Gammell P, Clynes M. Evaluation of recombinant human transferrin (DeltaFerrin™) as an iron chelator in serum-free media for mammalian cell culture. Cytotechnology 2006, 51(1):29-37. 10.1007/s10616-006-9011-x, 19002892.
    • (2006) Cytotechnology , vol.51 , Issue.1 , pp. 29-37
    • Keenan, J.1    Pearson, D.2    O'Driscoll, L.3    Gammell, P.4    Clynes, M.5
  • 27
    • 33747894122 scopus 로고    scopus 로고
    • Characterisation of recombinant unglycosylated human serum transferrin purified from Saccharomyces cerevisiae
    • 10.1007/s10534-005-5532-6, 16937257
    • Sargent PJ, Farnaud S, Cammack R, Zoller HM, Evans RW. Characterisation of recombinant unglycosylated human serum transferrin purified from Saccharomyces cerevisiae. Biometals 2006, 19(5):513-519. 10.1007/s10534-005-5532-6, 16937257.
    • (2006) Biometals , vol.19 , Issue.5 , pp. 513-519
    • Sargent, P.J.1    Farnaud, S.2    Cammack, R.3    Zoller, H.M.4    Evans, R.W.5
  • 28
    • 0000452573 scopus 로고
    • Expression and characterization of human lactoferrin in yeast Saccharomyces cerevisiae
    • Liang Q, Richardson T. Expression and characterization of human lactoferrin in yeast Saccharomyces cerevisiae. J Agric Food Chem 1993, 41:1800-1807.
    • (1993) J Agric Food Chem , vol.41 , pp. 1800-1807
    • Liang, Q.1    Richardson, T.2
  • 29
    • 0033596746 scopus 로고    scopus 로고
    • X-ray crystallography and mass spectroscopy reveal that the N-lobe of human transferrin expressed in Pichia pastoris is folded correctly but is glycosylated on serine-32
    • 10.1021/bi9824543, 10029548
    • Bewley MC, Tam BM, Grewal J, He S, Shewry S, Murphy ME, Mason AB, Woodworth RC, Baker EN, MacGillivray RT. X-ray crystallography and mass spectroscopy reveal that the N-lobe of human transferrin expressed in Pichia pastoris is folded correctly but is glycosylated on serine-32. Biochemistry 1999, 38(8):2535-2541. 10.1021/bi9824543, 10029548.
    • (1999) Biochemistry , vol.38 , Issue.8 , pp. 2535-2541
    • Bewley, M.C.1    Tam, B.M.2    Grewal, J.3    He, S.4    Shewry, S.5    Murphy, M.E.6    Mason, A.B.7    Woodworth, R.C.8    Baker, E.N.9    MacGillivray, R.T.10
  • 30
    • 78649971383 scopus 로고    scopus 로고
    • CellPrime™ recombinant human transferrin as an animal-free alternative to animal-derived transferrin or iron supplementation in cell culture applications
    • Limke T, Cunningham M, Chirkova L, Voorhamme D, Standfield S, Cavallaro D. CellPrime™ recombinant human transferrin as an animal-free alternative to animal-derived transferrin or iron supplementation in cell culture applications. BioProcess International 6(7):164-165.
    • BioProcess International , vol.6 , Issue.7 , pp. 164-165
    • Limke, T.1    Cunningham, M.2    Chirkova, L.3    Voorhamme, D.4    Standfield, S.5    Cavallaro, D.6
  • 31
    • 11944261204 scopus 로고
    • The secretion of human serum albumin from the yeast Saccharomyces cerevisiae using five different leader sequences
    • 10.1038/nbt0190-42, 1366511
    • Sleep D, Belfield GP, Goodey AR. The secretion of human serum albumin from the yeast Saccharomyces cerevisiae using five different leader sequences. Biotechnology (N Y) 1990, 8(1):42-46. 10.1038/nbt0190-42, 1366511.
    • (1990) Biotechnology (N Y) , vol.8 , Issue.1 , pp. 42-46
    • Sleep, D.1    Belfield, G.P.2    Goodey, A.R.3
  • 33
    • 0342906412 scopus 로고
    • Production of secreted proteins in yeast
    • London: Elsevier, Harris TJR
    • Collins SH. Production of secreted proteins in yeast. Protein production by biotechnology 1990, 61-77. London: Elsevier, Harris TJR.
    • (1990) Protein production by biotechnology , pp. 61-77
    • Collins, S.H.1
  • 34
    • 0017100245 scopus 로고
    • The detection of four molecular forms of human transferrin during the iron binding process
    • Makey DG, Seal US. The detection of four molecular forms of human transferrin during the iron binding process. Biochim Biophys Acta 1976, 453(1):250-256.
    • (1976) Biochim Biophys Acta , vol.453 , Issue.1 , pp. 250-256
    • Makey, D.G.1    Seal, U.S.2
  • 35
    • 0015919687 scopus 로고
    • The reaction of ferric salts with transferrin
    • Bates GW, Schlabach MR. The reaction of ferric salts with transferrin. J Biol Chem 1973, 248(9):3228-3232.
    • (1973) J Biol Chem , vol.248 , Issue.9 , pp. 3228-3232
    • Bates, G.W.1    Schlabach, M.R.2
  • 36
    • 0018564390 scopus 로고
    • A suppressor of mating-type locus mutations in Saccharomyces cerevisiae: evidence for and identification of cryptic mating-type loci
    • 1214119, 397913
    • Rine J, Strathern JN, Hicks JB, Herskowitz I. A suppressor of mating-type locus mutations in Saccharomyces cerevisiae: evidence for and identification of cryptic mating-type loci. Genetics 1979, 93(4):877-901. 1214119, 397913.
    • (1979) Genetics , vol.93 , Issue.4 , pp. 877-901
    • Rine, J.1    Strathern, J.N.2    Hicks, J.B.3    Herskowitz, I.4
  • 37
    • 57449090438 scopus 로고    scopus 로고
    • Modulation of chaperone gene expression in mutagenized Saccharomyces cerevisiae strains developed for recombinant human albumin production results in increased production of multiple heterologous proteins
    • 10.1128/AEM.01178-08, 2607181, 18931293
    • Payne T, Finnis C, Evans LR, Mead DJ, Avery SV, Archer DB, Sleep D. Modulation of chaperone gene expression in mutagenized Saccharomyces cerevisiae strains developed for recombinant human albumin production results in increased production of multiple heterologous proteins. Appl Environ Microbiol 2008, 74(24):7759-7766. 10.1128/AEM.01178-08, 2607181, 18931293.
    • (2008) Appl Environ Microbiol , vol.74 , Issue.24 , pp. 7759-7766
    • Payne, T.1    Finnis, C.2    Evans, L.R.3    Mead, D.J.4    Avery, S.V.5    Archer, D.B.6    Sleep, D.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.