Late acute rejection: Incidence, risk factors, and effect on graft survival and function

Pediatric Transplantation

Volumn 18, Issue 2, 2014, Pages 155-162

  Eid, Loai ^a   Tuchman, Shamir ^a   Moudgil, Asha ^a  

^a CHILDREN'S NATIONAL MEDICAL CENTER   (United States)

Author keywords

delayed graft function; donor specific antibodies; kidney transplantation; non adherence; pediatric; tacrolimus

Indexed keywords

TACROLIMUS;

ADOLESCENT; CHILD; FEMALE; GRAFT REJECTION; GRAFT SURVIVAL; HUMAN; INCIDENCE; KIDNEY TRANSPLANTATION; MALE; MULTIVARIATE ANALYSIS; PATIENT COMPLIANCE; RENAL INSUFFICIENCY; RETROSPECTIVE STUDY; RISK FACTOR; TREATMENT OUTCOME;

ADOLESCENT; CHILD; FEMALE; GRAFT REJECTION; GRAFT SURVIVAL; HUMANS; INCIDENCE; KIDNEY TRANSPLANTATION; MALE; MULTIVARIATE ANALYSIS; PATIENT COMPLIANCE; RENAL INSUFFICIENCY; RETROSPECTIVE STUDIES; RISK FACTORS; TACROLIMUS; TREATMENT OUTCOME;

EID: 84893868679     PISSN: 13973142     EISSN: 13993046     Source Type: Journal    
DOI: 10.1111/petr.12203     Document Type: Article

References (37)

1. NAPRTCS Annual Report. [database on the Internet]. [cited August 20, 2013]. Available at: http://web.emmes.com/study/ped/annlrept/2010-Report.pdf.
2. Matas AJ, Smith JM, Skeans MA, et al. OPTN/SRTR 2011 annual data report: Kidney. Am J Transplant 2013: 13 (Suppl 1): 11-46.
3. Hwang AH, Cho YW, Cicciarelli J, Mentser M, Iwaki Y, Hardy BE,. Risk factors for short- and long-term survival of primary cadaveric renal allografts in pediatric recipients: A UNOS analysis. Transplantation 2005: 80: 466-470. (Pubitemid 41209413)
4. Meier-Kriesche HU, Schold JD, Srinivas TR, Kaplan B,. Lack of improvement in renal allograft survival despite a marked decrease in acute rejection rates over the most recent era. Am J Transplant 2004: 4: 378-383. (Pubitemid 38282293)
5. Fletcher JT, Nankivell BJ, Alexander SI,. Chronic allograft nephropathy. Pediatr Nephrol 2009: 24: 1465-1471.
6. Leggat JE Jr, Ojo AO, Leichtman AB, et al. Long-term renal allograft survival: Prognostic implication of the timing of acute rejection episodes. Transplantation 1997: 63: 1268-1272. (Pubitemid 27212821)
7. Opelz G, Dohler B,. Influence of time of rejection on long-term graft survival in renal transplantation. Transplantation 2008: 85: 661-666. (Pubitemid 351398238)
8. Sijpkens YW, Doxiadis II, Mallat MJ, et al. Early versus late acute rejection episodes in renal transplantation. Transplantation 2003: 75: 204-208. (Pubitemid 36139673)
9. Morrissey PE, Reinert S, Yango A, Gautam A, Monaco A, Gohh R,. Factors contributing to acute rejection in renal transplantation: The role of noncompliance. Transpl Proc 2005: 37: 2044-2047. (Pubitemid 40956368)
10. Alexopoulos E, Papadimitriou M,. Late-acute renal allograft rejection and symptomless cytomegalovirus infection. Lancet 1995: 345: 794.
11. Babel N, Schwarzmann F, Prang N, et al. Association between Epstein-Barr virus infection and late acute transplant rejection in long-term transplant patients. Transplantation 2001: 72: 736-739. (Pubitemid 32802763)
12. Tan JY, Zhao N, Wu TX, et al. Steroid withdrawal increases risk of acute rejection but reduces infection: A meta-analysis of 1681 cases in renal transplantation. Transpl Proc 2006: 38: 2054-2056. (Pubitemid 46068485)
13. Hall BM, Bishop GA, Duggin GG, Horvath JS, Philips J, Tiller DJ,. Increased expression of HLA-DR antigens on renal tubular cells in renal transplants: Relevance to the rejection response. Lancet 1984: 2: 247-251. (Pubitemid 14057076)
14. Hardinger KL,. Rabbit antithymocyte globulin induction therapy in adult renal transplantation. Pharmacotherapy 2006: 26: 1771-1783. (Pubitemid 44885331)
15. Yarlagadda SG, Coca SG, Garg AX, et al. Marked variation in the definition and diagnosis of delayed graft function: A systematic review. Nephrol Dial Transplant 2008: 23: 2995-3003.
16. Schwartz GJ, Haycock GB, Edelmann CM Jr, Spitzer A,. A simple estimate of glomerular filtration rate in children derived from body length and plasma creatinine. Pediatrics 1976: 58: 259-263.
17. Levey AS, Bosch JP, Lewis JB, Greene T, Rogers N, Roth D,. A more accurate method to estimate glomerular filtration rate from serum creatinine: A new prediction equation. Modification of Diet in Renal Disease Study Group. Ann Intern Med 1999: 130: 461-470. (Pubitemid 29135798)
18. Tait BD, Susal C, Gebel HM, et al. Consensus guidelines on the testing and clinical management issues associated with HLA and non-HLA antibodies in transplantation. Transplantation 2013: 95: 19-47.
19. Sis B, Mengel M, Haas M, et al. Banff '09 meeting report: Antibody mediated graft deterioration and implementation of Banff working groups. Am J Transplant 2010: 10: 464-471.
20. Bock HA,. Steroid-resistant kidney transplant rejection: Diagnosis and treatment. J Am Soc Nephrol 2001: 12 (Suppl 17): S48-S52. (Pubitemid 32119054)
21. Hsiau M, Fernandez HE, Gjertson D, Ettenger RB, Tsai EW,. Monitoring nonadherence and acute rejection with variation in blood immunosuppressant levels in pediatric renal transplantation. Transplantation 2011: 92: 918-922.
22. Wood KJ, Goto R,. Mechanisms of rejection: Current perspectives. Transplantation 2012: 93: 1-10.
23. Narayanan R, Cardella CJ, Cattran DC, et al. Delayed graft function and the risk of death with graft function in living donor kidney transplant recipients. Am J Kidney Dis 2010: 56: 961-970.
24. Yarlagadda SG, Klein CL, Jani A,. Long-term renal outcomes after delayed graft function. Adv Chronic Kidney Dis 2008: 15: 248-256. (Pubitemid 351833143)
25. Wever KE, Wagener FA, Frielink C, et al. Diannexin protects against renal ischemia reperfusion injury and targets phosphatidylserines in ischemic tissue. PLoS ONE 2011: 6: e24276.
26. Hidalgo LG, Campbell PM, Sis B, et al. De novo donor-specific antibody at the time of kidney transplant biopsy associates with microvascular pathology and late graft failure. Am J Transplant 2009: 9: 2532-2541.
27. Lederer SR, Kluth-Pepper B, Schneeberger H, Albert E, Land W, Feucht HE,. Impact of humoral alloreactivity early after transplantation on the long-term survival of renal allografts. Kidney Int 2001: 59: 334-341. (Pubitemid 32055242)
28. Wiebe C, Gibson IW, Blydt-Hansen TD, et al. Evolution and clinical pathologic correlations of de novo donor-specific HLA antibody post kidney transplant. Am J Transplant 2012: 12: 1157-1167.
29. Lee PC, Terasaki PI, Takemoto SK, et al. All chronic rejection failures of kidney transplants were preceded by the development of HLA antibodies. Transplantation 2002: 74: 1192-1194. (Pubitemid 35216119)
30. Chaudhuri A, Ozawa M, Everly MJ, et al. The clinical impact of humoral immunity in pediatric renal transplantation. J Am Soc Nephrol 2013: 24: 655-664.
31. Staples B, Bravender T,. Drug compliance in adolescents: Assessing and managing modifiable risk factors. Paediatr Drugs 2002: 4: 503-513. (Pubitemid 34876156)
32. Cecka JM, Gjertson DW, Terasaki PI,. Pediatric renal transplantation: A review of the UNOS data. United Network for Organ Sharing. Pediatr Transplant 1997: 1: 55-64. (Pubitemid 127684809)
33. Jarzembowski T, John E, Panaro F, et al. Impact of non-compliance on outcome after pediatric kidney transplantation: An analysis in racial subgroups. Pediatr Transplant 2004: 8: 367-371. (Pubitemid 39062121)
34. Falkenstein K, Flynn L, Kirkpatrick B, Casa-Melley A, Dunn S,. Non-compliance in children post-liver transplant. Who are the culprits? Pediatr Transplant 2004: 8: 233-236. (Pubitemid 38788549)
35. Cleemput I, Kesteloot K, Vanrenterghem Y, de Geest S,. The economic implications of non-adherence after renal transplantation. PharmacoEconomics 2004: 22: 1217-1234. (Pubitemid 40075723)
36. Chisholm-Burns MA, Spivey CA, Rehfeld R, Zawaideh M, Roe DJ, Gruessner R,. Immunosuppressant therapy adherence and graft failure among pediatric renal transplant recipients. Am J Transplant 2009: 9: 2497-2504.
37. Pollock-Barziv SM, Finkelstein Y, Manlhiot C, et al. Variability in tacrolimus blood levels increases the risk of late rejection and graft loss after solid organ transplantation in older children. Pediatr Transplant 2010: 14: 968-975.