-
4
-
-
0021926605
-
Enzyme-activated irreversible inhibitors of monoamine oxidase: Phenylallylamine structure-activity relationships
-
DOI 10.1021/jm00380a007
-
McDonald, I. A.; Lacoste, J. M.; Bey, P.; Palfreyman, M. G.; Zreika, M. J. Med. Chem. 1985, 28, 186-193. doi:10.1021/jm00380a007 (Pubitemid 15170882)
-
(1985)
Journal of Medicinal Chemistry
, vol.28
, Issue.2
, pp. 186-193
-
-
McDonald, I.A.1
Lacoste, J.M.2
Bey, P.3
-
5
-
-
12144289000
-
SSR182289A, a selective and potent orally active thrombin inhibitor
-
DOI 10.1016/j.bmc.2004.01.016, PII S0968089604000495
-
Altenburger, J.-M.; Lassalle, G. Y.; Matrougui, M.; Galtier, D.; Jetha, J.-C.; Bocskei, Z.; Berry, C. N.; Lunven, C.; Lorrain, J.; Herault, J.-P.; Schaeffer, P.; O'Connor, S. E.; Herbert, J.-M. Bioorg. Med. Chem. 2004, 12, 1713-1730. doi:10.1016/j.bmc.2004.01.016 (Pubitemid 38340767)
-
(2004)
Bioorganic and Medicinal Chemistry
, vol.12
, Issue.7
, pp. 1713-1730
-
-
Altenburger, J.-M.1
Lassalle, G.Y.2
Matrougui, M.3
Galtier, D.4
Jetha, J.-C.5
Bocskei, Z.6
Berry, C.N.7
Lunven, C.8
Lorrain, J.9
Herault, J.-P.10
Schaeffer, P.11
O'Connor, S.E.12
Herbert, J.-M.13
-
6
-
-
0037294123
-
17(20) lyase
-
DOI 10.1016/S0968-0896(02)00434-0, PII S0968089602004340
-
Weintraub, P. M.; Holland, A. K.; Gates, C. A.; Moore, W. R.; Resvick, R. J.; Bey, P.; Peet, N. P. Bioorg. Med. Chem. 2003, 11, 427-431. doi:10.1016/S0968-0896(02)00434-0 (Pubitemid 36051033)
-
(2003)
Bioorganic and Medicinal Chemistry
, vol.11
, Issue.3
, pp. 427-431
-
-
Weintraub, P.M.1
Holland, A.K.2
Gates, C.A.3
Moore, W.R.4
Resvick, R.J.5
Bey, P.6
Peet, N.P.7
-
7
-
-
37049110300
-
-
doi:10.1039/C39810000930
-
Blackburn, G. M.; England, D. A.; Kolkmann, F. J. Chem. Soc., Chem. Commun. 1981, 930-932. doi:10.1039/C39810000930
-
(1981)
J. Chem. Soc., Chem. Commun
, pp. 930-932
-
-
Blackburn, G.M.1
England, D.A.2
Kolkmann, F.3
-
8
-
-
0347517811
-
The difluoromethylene group as a replacement for the labile oxygen in steroid sulfates: A new approach to steroid sulfatase inhibitors
-
DOI 10.1016/j.bmcl.2003.09.089
-
Lapierre, J.; Ahmed, V.; Chen, M.-J.; Ispahany, M.; Guillemette, J. G.; Taylor, S. D. Bioorg. Med. Chem. Lett. 2004, 14, 151-155. doi:10.1016/j.bmcl. 2003.09.089 (Pubitemid 38010211)
-
(2004)
Bioorganic and Medicinal Chemistry Letters
, vol.14
, Issue.1
, pp. 151-155
-
-
Lapierre, J.1
Ahmed, V.2
Chen, M.-J.3
Ispahany, M.4
Guillemette, J.G.5
Taylor, S.D.6
-
9
-
-
33846010139
-
-
doi:10.1021/ol062357z
-
Navidpour, L.; Lu, W.; Taylor, S. D. Org. Lett. 2006, 8, 5617-5620. doi:10.1021/ol062357z
-
(2006)
Org. Lett
, vol.8
, pp. 5617-5620
-
-
Navidpour, L.1
Lu, W.2
Taylor, S.D.3
-
10
-
-
37049083410
-
-
doi:10.1039/C39890001437
-
Motherwell, W. B.; Tozer, M. J.; Ross, B. C. J. Chem. Soc., Chem. Commun. 1989, 1437-1439. doi:10.1039/C39890001437
-
(1989)
J. Chem. Soc., Chem. Commun
, pp. 1437-1439
-
-
Motherwell, W.B.1
Tozer, M.J.2
Ross, B.C.3
-
12
-
-
0000406868
-
-
doi:10.1021/jo971019w
-
Nguyen, B. V.; Burton, D. J. J. Org. Chem. 1997, 62, 7758-7764. doi:10.1021/jo971019w
-
(1997)
J. Org. Chem
, vol.62
, pp. 7758-7764
-
-
Nguyen, B.V.1
Burton, D.J.2
-
13
-
-
0002577037
-
-
doi:10.1246/cl.1979.983
-
Hayashi, S.-i.; Nakai, T.; Ichikawa, N.; Burton, D. J.; Naae, D. G.; Kesling, H. S. Chem. Lett. 1979, 8, 983-986. doi:10.1246/cl.1979.983
-
(1979)
Chem. Lett
, vol.8
, pp. 983-986
-
-
Hayashi, S.-I.1
Nakai, T.2
Ichikawa, N.3
Burton, D.J.4
Naae, D.G.5
Kesling, H.S.6
-
14
-
-
0000256371
-
-
doi:10.1039/A703110F
-
Ichikawa, J.; Wada, Y.; Okauchi, T.; Minami, T. Chem. Commun. 1997, 1537-1538. doi:10.1039/A703110F
-
(1997)
Chem. Commun
, pp. 1537-1538
-
-
Ichikawa, J.1
Wada, Y.2
Okauchi, T.3
Minami, T.4
-
15
-
-
35948977642
-
-
doi:10.1021/ol702279w
-
Yokota, M.; Fujita, D.; Ichikawa, J. Org. Lett. 2007, 9, 4639-4642. doi:10.1021/ol702279w
-
(2007)
Org. Lett
, vol.9
, pp. 4639-4642
-
-
Yokota, M.1
Fujita, D.2
Ichikawa, J.3
-
16
-
-
0001884487
-
-
doi:10.1246/cl.1980.651
-
Hayashi, S.-i.; Nakai, T.; Ishikawa, N. Chem. Lett. 1980, 9, 651-654. doi:10.1246/cl.1980.651
-
(1980)
Chem. Lett
, vol.9
, pp. 651-654
-
-
Hayashi, S.-I.1
Nakai, T.2
Ishikawa, N.3
-
17
-
-
84858393772
-
-
doi:10.1021/cr200165q
-
Chelucci, G. Chem. Rev. 2012, 112, 1344-1462. doi:10.1021/cr200165q
-
(2012)
Chem. Rev
, vol.112
, pp. 1344-1462
-
-
Chelucci, G.1
-
18
-
-
84864535013
-
-
doi:10.6023/cjoc1104113
-
Liu, Y.; Deng, M.; Zhang, Z.; Ding, X.; Dai, Z.; Guan, J. Chin. J. Org. Chem. 2012, 32, 661-666. doi:10.6023/cjoc1104113
-
(2012)
Chin. J. Org. Chem
, vol.32
, pp. 661-666
-
-
Liu, Y.1
Deng, M.2
Zhang, Z.3
Ding, X.4
Dai, Z.5
Guan, J.6
-
19
-
-
50549213949
-
-
doi:10.1016/S0040-4039(01)89512-5
-
Fuqua, S. A.; Duncan, W. G.; Silverstein, R. M. Tetrahedron Lett. 1964, 5, 1461-1463. doi:10.1016/S0040-4039(01)89512-5
-
(1964)
Tetrahedron Lett
, vol.5
, pp. 1461-1463
-
-
Fuqua, S.A.1
Duncan, W.G.2
Silverstein, R.M.3
-
20
-
-
33947338284
-
-
doi:10.1021/jo01280a007
-
Herkes, F. E.; Burton, D. J. J. Org. Chem. 1967, 32, 1311-1318. doi:10.1021/jo01280a007
-
(1967)
J. Org. Chem
, vol.32
, pp. 1311-1318
-
-
Herkes, F.E.1
Burton, D.J.2
-
21
-
-
84881099054
-
-
doi:10.1039/C3CC44271C
-
Zheng, J.; Cai, J.; Lin, J.-H.; Guo, Y.; Xiao, J.-C. Chem. Commun. 2013, 49, 7513-7515. doi:10.1039/C3CC44271C
-
(2013)
Chem. Commun
, vol.49
, pp. 7513-7515
-
-
Zheng, J.1
Cai, J.2
Lin, J.-H.3
Guo, Y.4
Xiao, J.-C.5
-
22
-
-
49649155494
-
-
doi:10.1016/S0022-1139(00)82541-5
-
Naae, D. G.; Burton, D. J. J. Fluorine Chem. 1971, 1, 123-125. doi:10.1016/S0022-1139(00)82541-5
-
(1971)
J. Fluorine Chem
, vol.1
, pp. 123-125
-
-
Naae, D.G.1
Burton, D.J.2
-
23
-
-
84948510143
-
-
doi:10.1080/00397917308062035
-
Naae, D. G.; Burton, D. J. Synth. Commun. 1973, 3, 197-200. doi:10.1080/00397917308062035
-
(1973)
Synth. Commun
, vol.3
, pp. 197-200
-
-
Naae, D.G.1
Burton, D.J.2
-
24
-
-
14844338955
-
New methodology for the deoxygenative difluoromethylenation of aldehydes and ketones; unexpected formation of tetrafluorocyclopropanes
-
DOI 10.1021/ol047416s
-
Nowak, I.; Robins, J. M. Org. Lett. 2005, 7, 721-724. doi:10.1021/ol047416s (Pubitemid 40353480)
-
(2005)
Organic Letters
, vol.7
, Issue.4
, pp. 721-724
-
-
Nowak, I.1
Robins, M.J.2
-
25
-
-
84875511149
-
-
doi:10.1016/j.jfluchem.2013.02.026
-
Thomoson, C. S.; Martinez, H.; Dolbier, W. R., Jr. J. Fluorine Chem. 2013, 150, 53-59. doi:10.1016/j.jfluchem.2013.02.026
-
(2013)
J. Fluorine Chem
, vol.150
, pp. 53-59
-
-
Thomoson, C.S.1
Martinez, H.2
Dolbier Jr., W.R.3
-
26
-
-
84886640898
-
-
doi:10.1002/chem.201303248
-
Zheng, J.; Lin, J.-H.; Cai, J.; Xiao, J.-C. Chem.-Eur. J. 2013, 19, 15261-15266. doi:10.1002/chem.201303248 This article appeared online after our submission of this article. It is a paper describing the deoxygenative gem-difluoroolefination of carbonyl compounds with the difluorocarbene/phosphine procedures, i.e. HCF2Cl/propylene epoxide/n-Bu4NCl (cat.)/Ph3P.; FSO2CF2CO2TMS/NaF (cat.)/Ph3P.
-
(2013)
Chem.-Eur. J
, vol.19
, pp. 15261-15266
-
-
Zheng, J.1
Lin, J.-H.2
Cai, J.3
Xiao, J.-C.4
-
27
-
-
33845918216
-
2-Chloro-2,2-difluoroacetophenone: A non-ODS-based difluorocarbene precursor and its use in the difluoromethylation of phenol derivatives
-
DOI 10.1021/jo061799l
-
Zhang, L.; Zheng, J.; Hu, J. J. Org. Chem. 2006, 71, 9845-9848. doi:10.1021/jo061799l (Pubitemid 46032650)
-
(2006)
Journal of Organic Chemistry
, vol.71
, Issue.26
, pp. 9845-9848
-
-
Zhang, L.1
Zheng, J.2
Hu, J.3
-
28
-
-
36849071410
-
Chlorodifluoromethyl phenyl sulfone: A novel non-ozone-depleting substance-based difluorocarbene reagent for O- and N-difluoromethylations
-
DOI 10.1039/b713156a
-
Zheng, J.; Li, Y.; Zhang, L.; Hu, J.; Meuzelaar, G. J.; Federsel, H.-J. Chem. Commun. 2007, 5149-5151. doi:10.1039/B713156A (Pubitemid 350222808)
-
(2007)
Chemical Communications
, Issue.48
, pp. 5149-5151
-
-
Zheng, J.1
Li, Y.2
Zhang, L.3
Hu, J.4
Meuzelaar, G.J.5
Federsel, H.-J.6
-
29
-
-
66149091492
-
-
doi:10.1021/ol900567c
-
Zhang, W.; Wang, F.; Hu, J. Org. Lett. 2009, 11, 2109-2112. doi:10.1021/ol900567c
-
(2009)
Org. Lett
, vol.11
, pp. 2109-2112
-
-
Zhang, W.1
Wang, F.2
Hu, J.3
-
30
-
-
84555189244
-
-
doi:10.1002/cjoc.201100325
-
Wang, F.; Huang, W.; Hu, J. Chin. J. Chem. 2011, 29, 2717-2721. doi:10.1002/cjoc.201100325
-
(2011)
Chin. J. Chem
, vol.29
, pp. 2717-2721
-
-
Wang, F.1
Huang, W.2
Hu, J.3
-
31
-
-
79751489588
-
-
doi:10.1039/c0cc04548a
-
Wang, F.; Zhang, W.; Zhu, J.; Li, H.; Huang, K.-W.; Hu, J. Chem. Commun. 2011, 47, 2411-2413. doi:10.1039/c0cc04548a
-
(2011)
Chem. Commun
, vol.47
, pp. 2411-2413
-
-
Wang, F.1
Zhang, W.2
Zhu, J.3
Li, H.4
Huang, K.-W.5
Hu, J.6
-
32
-
-
84893839655
-
-
Supporting Information File 1
-
For preliminary results on the difluoromethylation of O, S, and N-nucleophiles with TMSCF2Cl under aqueous basic conditions, see Supporting Information File 1.
-
-
-
-
33
-
-
79960629751
-
-
doi:10.1002/anie.201101691
-
Wang, F.; Luo, T.; Hu, J.; Wang, Y.; Krishnan, H. S.; Jog, P. V.; Ganesh, S. K.; Prakash, G. K. S.; Olah, G. A. Angew. Chem., Int. Ed. 2011, 50, 7153-7157. doi:10.1002/anie.201101691
-
(2011)
Angew. Chem., Int. Ed
, vol.50
, pp. 7153-7157
-
-
Wang, F.1
Luo, T.2
Hu, J.3
Wang, Y.4
Krishnan, H.S.5
Jog, P.V.6
Ganesh, S.K.7
Prakash, G.K.S.8
Olah, G.A.9
-
34
-
-
84887510998
-
-
doi:10.1002/anie.201306703
-
Li, L.; Wang, F.; Ni, C.; Hu, J. Angew. Chem., Int. Ed. 2013, 52, 12390-12394. doi:10.1002/anie.201306703
-
(2013)
Angew. Chem., Int. Ed
, vol.52
, pp. 12390-12394
-
-
Li, L.1
Wang, F.2
Ni, C.3
Hu, J.4
-
35
-
-
0006598557
-
-
doi:10.1016/S0040-4039(01)80208-2
-
Ruppert, I.; Schlich, K.; Volbach, W. Tetrahedron Lett. 1984, 25, 2195-2198. doi:10.1016/S0040-4039(01)80208-2
-
(1984)
Tetrahedron Lett
, vol.25
, pp. 2195-2198
-
-
Ruppert, I.1
Schlich, K.2
Volbach, W.3
-
36
-
-
0038390641
-
-
doi:10.1016/0022-328X(90)80061-4
-
Broicher, V.; Geffken, D. J. Organomet. Chem. 1990, 381, 315-320. doi:10.1016/0022-328X(90)80061-4
-
(1990)
J. Organomet. Chem
, vol.381
, pp. 315-320
-
-
Broicher, V.1
Geffken, D.2
-
37
-
-
0345244392
-
Preparation of and fluoroalkylation with (chlorodifluoromethyl) trimethylsilane, difluorobis(trimethylsilyl)methane, and 1,1,2,2-tetrafluoro-1, 2-bis(trimethylsilyl)ethane
-
DOI 10.1021/ja962990n, PII S0002786396029903
-
Yudin, A. K.; Prakash, G. K. S.; Deffieux, D.; Bradley, M.; Bau, R.; Olah, G. A. J. Am. Chem. Soc. 1997, 119, 1572-1581. doi:10.1021/ja962990n (Pubitemid 27145500)
-
(1997)
Journal of the American Chemical Society
, vol.119
, Issue.7
, pp. 1572-1581
-
-
Yudin, A.K.1
Prakash, G.K.S.2
Deffieux, D.3
Bradley, M.4
Bau, R.5
Olah, G.A.6
-
38
-
-
0038441453
-
Preparation of tri- and difluoromethylsilanes via an unusual magnesium metal-mediated reductive tri- and difluoromethylation of chlorosilanes using tri- and difluoromethyl sulfides, sulfoxides, and sulfones
-
DOI 10.1021/jo030110z
-
Prakash, G. K. S.; Hu, J.; Olah, G. A. J. Org. Chem. 2003, 68, 4457-4463. doi:10.1021/jo030110z (Pubitemid 36622735)
-
(2003)
Journal of Organic Chemistry
, vol.68
, Issue.11
, pp. 4457-4463
-
-
Prakash, G.K.S.1
Hu, J.2
Olah, G.A.3
-
39
-
-
84870712049
-
-
doi:10.1126/science.1227859
-
Prakash, G. K. S.; Jog, P. V.; Batamack, P. T. D.; Olah, G. A. Science 2012, 338, 1324-1327. doi:10.1126/science.1227859
-
(2012)
Science
, vol.338
, pp. 1324-1327
-
-
Prakash, G.K.S.1
Jog, P.V.2
Batamack, P.T.D.3
Olah, G.A.4
-
40
-
-
84863633032
-
-
doi:10.1021/jo301094b
-
Kosobokov, M. D.; Dilman, A. D.; Levin, V. V.; Struchkova, M. I. J. Org. Chem. 2012, 77, 5850-5855. doi:10.1021/jo301094b
-
(2012)
J. Org. Chem
, vol.77
, pp. 5850-5855
-
-
Kosobokov, M.D.1
Dilman, A.D.2
Levin, V.V.3
Struchkova, M.I.4
-
41
-
-
45049084631
-
-
doi:10.1016/j.tetlet.2008.05.053
-
Matsukawa, S.; Saijo, M. Tetrahedron Lett. 2008, 49, 4655-4657. doi:10.1016/j.tetlet.2008.05.053
-
(2008)
Tetrahedron Lett
, vol.49
, pp. 4655-4657
-
-
Matsukawa, S.1
Saijo, M.2
-
42
-
-
33947489916
-
-
doi:10.1021/ja01080a049
-
Miller, N. E. J. Am. Chem. Soc. 1965, 87, 390-391. doi:10.1021/ ja01080a049
-
(1965)
J. Am. Chem. Soc
, vol.87
, pp. 390-391
-
-
Miller, N.E.1
-
43
-
-
53849125851
-
-
doi:10.1002/chem.200801358
-
McNulty, J.; Das, P. Chem.-Eur. J. 2008, 14, 8469-8472. doi:10.1002/chem.200801358
-
(2008)
Chem.-Eur. J
, vol.14
, pp. 8469-8472
-
-
McNulty, J.1
Das, P.2
|