Improved glucose-stimulated insulin secretion by selective intraislet inhibition of angiotensin II type 1 receptor expression in isolated islets of db/db mice

International Journal of Endocrinology

Volumn 2013, Issue , 2013, Pages

  Zhang, Zhen ^a   Liu, Chunyan ^a   Gan, Zhenhua ^a   Wang, Xinyi ^a   Yi, Qiuyan ^a   Liu, Yanqing ^a   Wang, Yingzhijie ^a   Lu, Bin ^a   Du, Hong ^a   Shao, Jiaqing ^a   Wang, Jun ^a  

^a SOUTHERN MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 84893861284     PISSN: 16878337     EISSN: 16878345     Source Type: Journal    
DOI: 10.1155/2013/319586     Document Type: Article

References (43)

1. Hansson L., Lindholm L. H., Niskanen L., Lanke J., Hedner T., Niklason A., Luomanmäki K., Dahlöf B., De Faire U., Mörlin C., Karlberg B. E., Wester P. O., Björck J., Effect of angiotensin-converting-enzyme inhibition compared with conventional therapy on cardiovascular morbidity and mortality in hypertension: the Captopril Prevention Project (CAPPP) randomised trial. The Lancet 1999 353 9153 611 616 2-s2.0-0033034404 10.1016/S0140-6736(98) 05012-0 (Pubitemid 29087980)
2. Andraws R., Brown D. L., Effect of inhibition of the Renin-angiotensin system on development of type 2 diabetes mellitus (meta-analysis of randomized trials). American Journal of Cardiology 2007 99 7 1006 1012 2-s2.0-33947577435 10.1016/j.amjcard.2006.10.068 (Pubitemid 46483294)
3. Dahlöf B., Devereux R. B., Kjeldsen S. E., Julius S., Beevers G., De Faire U., Fyhrquist F., Ibsen H., Kristiansson K., Lederballe-Pedersen O., Lindholm L. H., Nieminen M. S., Omvik P., Oparil S., Wedel H., Cardiovascular morbidity and mortality in the Losartan Intervention For Endpoint reduction in hypertension study (LIFE): a randomised trial against atenolol. The Lancet 2002 359 9311 995 1003 2-s2.0-0037160968 10.1016/S0140-6736(02)08089-3 (Pubitemid 34286536)
4. Scheen A. J., Renin-angiotensin system inhibition prevents type 2 diabetes mellitus: part 1. A meta-analysis of randomised clinical trials. Diabetes and Metabolism 2004 30 6 487 496 2-s2.0-11244294737 (Pubitemid 40070350)
5. Tahmasebi M., Puddefoot J. R., Inwang E. R., Vinson G. P., The tissue renin-angiotensin system in human pancreas. Journal of Endocrinology 1999 161 2 317 322 2-s2.0-0032983046 10.1677/joe.0.1610317 (Pubitemid 29244259)
6. Carlsson P. O., The renin-angiotensin system in the endocrine pancreas. Journal of the Pancreas 2001 2 1 26 32 2-s2.0-0035239910
7. Montgomery H., Humphries S. E., Leung P. S., Renin-angiotensin systems: the new frontier. International Journal of Biochemistry and Cell Biology 2003 35 6 758 2-s2.0-0037409318 10.1016/S1357-2725(03)00003-7 (Pubitemid 36379315)
8. Kampf C., Lau T., Olsson R., Leung P. S., Carlsson P.-O., Angiotensin II type 1 receptor inhibition markedly improves the blood perfusion, oxygen tension and first phase of glucose-stimulated insulin secretion in revascularised syngeneic mouse islet grafts. Diabetologia 2005 48 6 1159 1167 2-s2.0-21344467929 10.1007/s00125-005-1761-z (Pubitemid 40909652)
9. Leung P. S., Carlsson P. O., Pancreatic islet renin angiotensin system: its novel roles in islet function and in diabetes mellitus. Pancreas 2005 30 4 293 298 2-s2.0-17844367376 10.1097/01.mpa.0000158028.76666.76 (Pubitemid 40586804)
10. Shao J., Iwashita N., Du H., Wang Y., Wang Y., Zhao M., Wang J., Watada H., Kawamori R., Angiotensin II receptor blocker provides pancreatic β -cell protection independent of blood pressure lowering in diabetic db/db mice. Acta Pharmacologica Sinica 2007 28 2 246 257 2-s2.0-33846508489 10.1111/j.1745-7254.2007.00492.x (Pubitemid 46155543)
11. Shao J., Iwashita N., Ikeda F., Ogihara T., Uchida T., Shimizu T., Uchino H., Hirose T., Kawamori R., Watada H., Beneficial effects of candesartan, an angiotensin II type 1 receptor blocker, on β -cell function and morphology in db/db mice. Biochemical and Biophysical Research Communications 2006 344 4 1224 1233 2-s2.0-33646200241 10.1016/j.bbrc.2006.04.011
12. Klaman L. D., Boss O., Peroni O. D., Kim J. K., Martino J. L., Zabolotny J. M., Moghal N., Lubkin M., Kim Y., Sharpe A. H., Stricker-Krongrad A., Shulman G. I., Neel B. G., Kahn B. B., Increased energy expenditure, decreased adiposity, and tissue-specific insulin sensitivity in protein-tyrosine phosphatase 1B-deficient mice. Molecular and Cellular Biology 2000 20 15 5479 5489 2-s2.0-0033942614 10.1128/MCB.20.15.5479-5489.2000 (Pubitemid 30482885)
13. Rothenberg P. L., Willison L. D., Simon J., Wolf B. A., Glucose-induced insulin receptor tyrosine phosphorylation in insulin- secreting β -cells. Diabetes 1995 44 7 802 809 2-s2.0-0029088719
14. Harbeck M. C., Louie D. C., Howland J., Wolf B. A., Rothenberg P. L., Expression of insulin receptor mRNA and insulin receptor substrate 1 in pancreatic islet β -cells. Diabetes 1996 45 6 711 717 2-s2.0-0029893530 (Pubitemid 26168581)
15. Leibiger I. B., Leibiger B., Moede T., Berggren P., Exocytosis of insulin promotes insulin gene transcription via the insulin receptor/PI-3 kinase/p70 s6 kinase and CaM kinase pathways. Molecular Cell 1998 1 6 933 938 2-s2.0-0032061042 (Pubitemid 128379078)
16. Xu G. G., Gao Z., Borge P. D. Jr., Wolf B. A., Insulin receptor substrate 1-induced inhibition of endoplasmic reticulum Ca2+ uptake in β -cells: autocrine regulation of intracellular Ca2+ homeostasis and insulin secretion. Journal of Biological Chemistry 1999 274 25 18067 18074 2-s2.0-0033581001 10.1074/jbc.274.25.18067 (Pubitemid 29283336)
17. Ran J., Hirano T., Adachi M., Chronic ANG II infusion increases plasma triglyceride level by stimulating hepatic triglyceride production in rats. American Journal of Physiology-Endocrinology and Metabolism 2004 287 5 E955 E961 2-s2.0-6044267993 10.1152/ajpendo.00199.2004 (Pubitemid 39382933)
18. de Kloet A. D., Krause E. G., Woods S. C., The renin angiotensin system and the metabolic syndrome. Physiology and Behavior 2010 100 5 525 534 2-s2.0-77953713390 10.1016/j.physbeh.2010.03.018
19. Chappell M. C., Characterization of angiotensin II receptor subtypes in pancreatic acinar AR42J cells. Peptides 1995 16 4 741 747 2-s2.0-0029042966 10.1016/0196-9781(95)00044-K
20. Tikellis C., Wookey P. J., Candido R., Andrikopoulos S., Thomas M. C., Cooper M. E., Improved islet morphology after blockade of the Renin-angiotensin system in the ZDF rat. Diabetes 2004 53 4 989 997 2-s2.0-1842475446 10.2337/diabetes.53.4.989 (Pubitemid 38436611)
21. Kwan Y. C., Leung P. S., Angiotensin II type 1 receptor antagonism mediates uncoupling protein 2-driven oxidative stress and ameliorates pancreatic islet β -cell function in young type 2 diabetic mice. Antioxidants and Redox Signaling 2007 9 7 869 878 2-s2.0-34250333856 10.1089/ars.2007.1590 (Pubitemid 46919590)
22. Yuan L., Xin L., Xu G., Effect of renin-andiotensin system blockade in islet function in diabetic rats. Journal of Endocrinological Investigation 2010 33 1 13 19
23. Li X., Yuan L., Xu G., Qi C., Li J., Li H., Cheng S., Effect of renin angiotensin system blockade on the islet microvessel density of diabetic rats and its relationship with islet function. Journal of Huazhong University of Science and Technology 2009 29 6 684 688 2-s2.0-77149145847 10.1007/s11596-009- 0602-6
24. Chu K. Y., Cheng Q., Chen C., Au L. S., Seto S. W., Tuo Y., Motin L., Kwan Y. W., Leung P. S., Angiotensin II exerts glucose-dependent effects on Kv currents in mouse pancreatic β -cells via angiotensin II type 2 receptors. American Journal of Physiology 2010 298 2 C313 C323 2-s2.0-75749131115 10.1152/ajpcell.00575.2008
25. Xu G. G., Gao Z., Borge P. D. Jr., Wolf B. A., Insulin receptor substrate 1-induced inhibition of endoplasmic reticulum Ca2+ uptake in β -cells: autocrine regulation of intracellular Ca2+ homeostasis and insulin secretion. Journal of Biological Chemistry 1999 274 25 18067 18074 2-s2.0-0033581001 10.1074/jbc.274.25.18067 (Pubitemid 29283336)
26. Taylor S. I., Deconstructing type 2 diabetes. Cell 1999 97 1 9 12 2-s2.0-0033515429 (Pubitemid 29165884)
27. Kalupahana N. S., Moustaid-Moussa N., The renin-angiotensin system: a link between obesity, inflammation and insulin resistance. Obesity Reviews 2012 13 2 136 149 2-s2.0-84855457188 10.1111/j.1467-789X.2011.00942.x
28. Aspinwall C. A., Qian W., Roper M. G., Kulkarni R. N., Kahn C. R., Kennedy R. T., Roles of insulin receptor substrate-1, phosphatidylinositol 3-kinase, and release of intracellular Ca2+ stores in insulin-stimulated insulin secretion in β -cells. Journal of Biological Chemistry 2000 275 29 22331 22338 2-s2.0-0034698052 10.1074/jbc.M909647199 (Pubitemid 30621818)
29. Guillam M. T., Hümmler E., Schaerer E., Wu J.-Y., Birnbaum M. J., Beermann F., Schmidt A., Dériaz N., Thorens B., Early diabetes and abnormal postnatal pancreatic islet development in mice lacking Glut-2. Nature Genetics 1997 17 3 327 330 2-s2.0-0030707689 10.1038/ng1197-327 (Pubitemid 27475998)
30. Spégel P., Ekholm E., Tuomi T., Metabolite profiling reveals normal metabolic control in carriers of mutations in the glucokinase gene (MODY2). Diabetes 2013 62 2 653 661
31. Capuano M., Garcia-Herrero C. M., Tinto N., Glucokinase (GCK) mutations and their characterization in MODY2 children of Southern Italy. PLoS ONE 2012 7 6 e38906 10.1371/journal.pone.0038906
32. Im Walde S. S., Dohle S. C., Schott-Ohly P., Gleichmann H., Molecular target structures in alloxan-induced diabetes in mice. Life Sciences 2002 71 14 1681 1694 2-s2.0-0037162981 10.1016/S0024-3205(02)01918-5 (Pubitemid 34879073)
33. Scheen A. J., Renin-angiotensin system inhibition prevents type 2 diabetes mellitus: part 2. Overview of physiological and biochemical mechanisms. Diabetes and Metabolism 2004 30 6 498 505 2-s2.0-11244297241 (Pubitemid 40073639)
34. Andreozzi F., Laratta E., Sciacqua A., Perticone F., Sesti G., Angiotensin II impairs the insulin signaling pathway promoting production of nitric oxide by inducing phosphorylation of insulin receptor substrate-1 on Ser12 and Ser616 in human umbilical vein endothelial cells. Circulation Research 2004 94 9 1211 1218 2-s2.0-2442691522 10.1161/01.RES.0000126501.34994.96 (Pubitemid 38656407)
35. Kasper S. O., Phillips E. E., Castle S. M., Daley B. J., Enderson B. L., Karlstad M. D., Blockade of the renin-angiotensin system improves insulin receptor signaling and insulin-stimulated skeletal muscle glucose transport in burn injury. Shock 2011 35 1 80 85 2-s2.0-78650771326 10.1097/SHK. 0b013e3181e762da
36. Dunning B. E., Gerich J. E., The role of α -cell dysregulation in fasting and postprandial hyperglycemia in type 2 diabetes and therapeutic implications. Endocrine Reviews 2007 28 3 253 283 2-s2.0-34250854205 10.1210/er.2006-0026 (Pubitemid 46984828)
37. Frantz E. D. C., Crespo-Mascarenhas C., Barreto-Vianna A. R. C., Renin-angiotensin system blockers protect pancreatic islets against diet-induced obesity and insulin resistance in mice. PLoS ONE 8 7 e67192 10.1371/journal.pone.0067192
38. Patel Y. C., Amherdt M., Orci L., Quantitative electron microscopic autoradiography of insulin, glucagon, and somatostatin binding sites on islets. Science 1982 217 4565 1155 1156 2-s2.0-0019961892 (Pubitemid 12069037)
39. Bhathena S. J., Oie H. K., Gazdar A. F., Insulin, glucagon, and somatostatin receptors on cultured cells and clones from rat islet cell tumor. Diabetes 1982 31 6 521 531 2-s2.0-0020070165 (Pubitemid 12119339)
40. Kisanuki K., Kishikawa H., Araki E., Shirotani T., Uehara M., Isami S., Ura S., Jinnouchi H., Miyamura N., Shichiri M., Expression of insulin receptor on clonal pancreatic alpha cells and its possible role for insulin-stimulated negative regulation of glucagon secretion. Diabetologia 1995 38 4 422 429 2-s2.0-0028919521 10.1007/s001250050301
41. Velloso L. A., Carneiro E. M., Crepaldi S. C., Boschero A. C., Saad M. J. A., Glucose- and insulin-induced phosphorylation of the insulin receptor and its primary substrates IRS-1 and IRS-2 in rat pancreatic islets. FEBS Letters 1995 377 3 353 357 2-s2.0-0029559161 10.1016/0014-5793(95)01370-9 (Pubitemid 26025724)
42. Kaneko K., Shirotani T., Araki E., Matsumoto K., Taguchi T., Motoshima H., Yoshizato K., Kishikawa H., Shichiri M., Insulin inhibits glucagon secretion by the activation of PI3-kinase in In-R1-G9 cells. Diabetes Research and Clinical Practice 1999 44 2 83 92 2-s2.0-0032868694 10.1016/S0168-8227(99)00021- 2 (Pubitemid 29447673)
43. Xu E., Kumar M., Zhang Y., Ju W., Obata T., Zhang N., Liu S., Wendt A., Deng S., Ebina Y., Wheeler M. B., Braun M., Wang Q., Intra-islet insulin suppresses glucagon release via GABA-GABAA receptor system. Cell Metabolism 2006 3 1 47 58 2-s2.0-33645051453 10.1016/j.cmet.2005.11.015