Glucokinase (GCK) mutations and their characterization in MODY2 children of Southern italy

PLoS ONE

Volumn 7, Issue 6, 2012, Pages

  Capuano, Marina ^a,b   Garcia Herrero, Carmen Maria ^c,d   Tinto, Nadia ^a,b   Carluccio, Carla ^a,b   Capobianco, Valentina ^e   Coto, Iolanda ^a,b   Cola, Arturo ^a,b   Iafusco, Dario ^f   Franzese, Adriana ^a   Zagari, Adriana ^a,b   Navas, Maria Angeles ^c,d   Sacchetti, Lucia ^a,b  

^a UNIVERSITY OF NAPLES FEDERICO II   (Italy)

^b CEINGE BIOTECNOLOGIE AVANZATE   (Italy)

^c UNIVERSIDAD COMPLUTENSE DE MADRID   (Spain)

^d INSTITUTO DE SALUD CARLOS III   (Spain)

^e IRCCS SDN   (Italy)

^f SECOND UNIVERSITY OF NAPLES   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE; ARGININE; ASPARTIC ACID; CYSTEINE; GLUCOKINASE; PHENYLALANINE; THREONINE; TYROSINE; VALINE;

ALPHA HELIX; AMINO ACID SUBSTITUTION; ARTICLE; BETA SHEET; DNA POLYMORPHISM; ENZYME ACTIVITY; ENZYME KINETICS; ENZYME STABILITY; ENZYME STRUCTURE; GCK GENE; GENE; GENE MUTATION; HUMAN; ITALY; MAJOR CLINICAL STUDY; MATURITY ONSET DIABETES MELLITUS; MISSENSE MUTATION; NUCLEOTIDE SEQUENCE; PHENOTYPE; PROTEIN FOLDING; SEQUENCE ANALYSIS;

ADENOSINE TRIPHOSPHATE; CHILD; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; COMPUTATIONAL BIOLOGY; DIABETES MELLITUS, TYPE 2; FEMALE; HUMANS; ITALY; KINETICS; MALE; MODELS, MOLECULAR; MUTAGENESIS, SITE-DIRECTED; MUTATION; POLYMORPHISM, GENETIC; PROTEIN CONFORMATION; PROTEIN-SERINE-THREONINE KINASES;

EID: 84862690479     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0038906     Document Type: Article

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