Metabolomic analysis of uremic toxins by liquid chromatography/electrospray ionization-tandem mass spectrometry

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 878, Issue 20, 2010, Pages 1662-1668

  Kikuchi, Kaori ^a   Itoh, Yoshiharu ^a   Tateoka, Ryoko ^a   Ezawa, Atsuko ^a   Murakami, Kenjiro ^a   Niwa, Toshimitsu ^b  

^a KUREHA CORPORATION   (Japan)

^b NAGOYA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

Chronic renal failure; Indoxyl sulfate; Liquid chromatography electrospray ionization tandem mass spectrometry; Metabolome; Principal component analysis; Uremic toxin

Indexed keywords

CHRONIC RENAL FAILURE; INDOXYL SULFATE; METABOLOMES; TANDEM MASS SPECTROMETRY; UREMIC TOXIN; UREMIC TOXINS;

ACIDS; BIOMOLECULES; BODY FLUIDS; IONIZATION OF LIQUIDS; LIQUIDS; MASS SPECTROMETRY; METABOLISM; METABOLITES; PARTICLE DETECTORS; QUALITY ASSURANCE; RATS; TOXIC MATERIALS;

PRINCIPAL COMPONENT ANALYSIS;

CREATININE; HIPPURIC ACID; INDICAN; PARA CRESYL SULFATE; PHENYL SULFATE; UNCLASSIFIED DRUG; UREMIC TOXIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD LEVEL; CHRONIC KIDNEY FAILURE; CONTROLLED STUDY; CREATININE CLEARANCE; ELECTROSPRAY MASS SPECTROMETRY; LIQUID CHROMATOGRAPHY; MALE; METABOLOMICS; NEPHRECTOMY; NONHUMAN; PRINCIPAL COMPONENT ANALYSIS; PRIORITY JOURNAL; RAT;

ANIMALS; CHROMATOGRAPHY, LIQUID; CRESOLS; DISEASE MODELS, ANIMAL; HIPPURATES; HUMANS; INDICAN; KIDNEY; KIDNEY FAILURE, CHRONIC; MALE; METABOLOMICS; RATS; RATS, SPRAGUE-DAWLEY; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; SULFURIC ACID ESTERS; TOXINS, BIOLOGICAL;

RATTUS;

EID: 77952693346     PISSN: 15700232     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jchromb.2009.11.040     Document Type: Article

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