Elevated serum levels of circulating immunoinflammation-related protein complexes are associated with cancer

Journal of Proteome Research

Volumn 13, Issue 2, 2014, Pages 710-719

  Wang, Yanying ^a   Song, Gaoguang ^a   Wang, Yanmin ^b   Qiu, Ling ^c   Qin, Xuzhen ^c   Liu, Hui ^a   Li, Fang ^a   Wang, Xiaodong ^a   Li, Fenjie ^a   Guo, Shuai ^a   Zhang, Yaping ^a   Li, Zhili ^a  

^a INSTITUTE OF BASIC MEDICAL SCIENCES   (China)

^b Heze Municipal Hospital   (China)

^c PEKING UNION MEDICAL COLLEGE HOSPITAL   (China)

Author keywords

cancer; immunoinflammation related protein complexes; native gel; serum; supramolecular biomarker

Indexed keywords

BLOOD PROTEINS; HUMANS; INFLAMMATION; MIDDLE AGED; NATIVE POLYACRYLAMIDE GEL ELECTROPHORESIS; NEOPLASMS;

EID: 84893851443     PISSN: 15353893     EISSN: 15353907     Source Type: Journal    
DOI: 10.1021/pr4008255     Document Type: Article

References (31)

1. Jemal, A.; Bray, F.; Center, M. M.; Ferlay, J.; Ward, E.; Forman, D. Global cancer statistics CA Cancer J. Clin. 2011, 61, 69-90
2. Hanash, S. M.; Pitteri, S. J.; Faca, V. M. Mining the plasma proteome for cancer biomarkers Nature 2008, 452, 571-579
3. Ioannidis, J. P.; Panagiotou, O. A. Comparison of effect sizes associated with biomarkers reported in highly cited individual articles and in subsequent meta-analyses JAMA 2011, 305, 2200-2210
4. Hedstrom, J.; Kemppainen, E.; Andersen, J.; Jokela, H.; Puolakkainen, P.; Stenman, U. H. A comparison of serum trypsinogen-2 and trypsin-2-alpha1- antitrypsin complex with lipase and amylase in the diagnosis and assessment of severity in the early phase of acute pancreatitis Am. J. Gastroenterol. 2001, 96, 424-430
5. Hedstrom, J.; Sainio, V.; Kemppainen, E.; Haapiainen, R.; Kivilaakso, E.; Schroder, T.; Leinonen, J.; Stenman, U. H. Serum complex of trypsin 2 and alpha 1 antitrypsin as diagnostic and prognostic marker of acute pancreatitis: clinical study in consecutive patients BMJ [Br. Med. J.] 1996, 313, 333-337
6. Kemppainen, E.; Hedstrom, J.; Puolakkainen, P.; Halttunen, J.; Sainio, V.; Haapiainen, R.; Kivilaakso, E.; Stenman, U. H. Increased serum trypsinogen 2 and trypsin 2-alpha 1 antitrypsin complex values identify endoscopic retrograde cholangiopancreatography induced pancreatitis with high accuracy Gut 1997, 41, 690-695
7. Hedstrom, J.; Haglund, C.; Haapiainen, R.; Stenman, U. H. Serum trypsinogen-2 and trypsin-2-alpha(1)-antitrypsin complex in malignant and benign digestive-tract diseases. Preferential elevation in patients with cholangiocarcinomas Int. J. Cancer 1996, 66, 326-331
8. Wittig, I.; Braun, H. P.; Schagger, H. Blue native PAGE Nat. Protoc. 2006, 1, 418-428
9. Wittig, I.; Schagger, H. Native electrophoretic techniques to identify protein-protein interactions Proteomics 2009, 9, 5214-5223
10. Elsasser, S.; Schmidt, M.; Finley, D. Characterization of the proteasome using native gel electrophoresis Methods Enzymol. 2005, 398, 353-363
11. Wang, X.; Li, F.; Song, G.; Guo, S.; Liu, H.; Chen, G.; Li, Z. Broad-spectrum four-dimensional orthogonal electrophoresis: a novel comprehensively feasible system for protein complexomics investigation Mol. Cell. Proteomics 2012, 11, 786-799
12. Grivennikov, S. I.; Greten, F. R.; Karin, M. Immunity, inflammation, and cancer Cell 2010, 140, 883-899
13. Mantovani, A.; Allavena, P.; Sica, A.; Balkwill, F. Cancer-related inflammation Nature 2008, 454, 436-444
14. Tan, T. T.; Coussens, L. M. Humoral immunity, inflammation and cancer Curr. Opin. Immunol. 2007, 19, 209-216
15. Pine, S. R.; Mechanic, L. E.; Enewold, L.; Chaturvedi, A. K.; Katki, H. A.; Zheng, Y. L.; Bowman, E. D.; Engels, E. A.; Caporaso, N. E.; Harris, C. C. Increased levels of circulating interleukin 6, interleukin 8, C-reactive protein, and risk of lung cancer J. Natl. Cancer Inst. 2011, 103, 1112-1122
16. Chen, G.; Luo, Y.; Wang, X.; Zhao, Z.; Liu, H.; Zhang, H.; Li, Z. A relatively simple and economical protocol for proteomic analyses of human 20S proteasome: Compatible with both scaled-up and scaled-down purifications Electrophoresis 2009, 30, 2422-2430
17. Schreiber, H.; Rowley, D. A. Cancer. Awakening immunity Science 2010, 330, 761-762
18. Finn, O. J. Cancer immunology N. Engl. J. Med. 2008, 358, 2704-2715
19. Cuzick, J.; Otto, F.; Baron, J. A.; Brown, P. H.; Burn, J.; Greenwald, P.; Jankowski, J.; La Vecchia, C.; Meyskens, F.; Senn, H. J.; Thun, M. Aspirin and non-steroidal anti-inflammatory drugs for cancer prevention: an international consensus statement Lancet Oncol. 2009, 10, 501-507
20. Lin, H. L.; Lin, H. C.; Lin, C. C. Increased risk of colorectal cancer among patients with biliary tract inflammation: a 5-year follow-up study Int. J. Cancer 2011, 128, 447-452
21. Pontisso, P.; Quarta, S.; Caberlotto, C.; Beneduce, L.; Marino, M.; Bernardinello, E.; Tono, N.; Fassina, G.; Cavalletto, L.; Gatta, A.; Chemello, L. Progressive increase of SCCA-IgM immune complexes in cirrhotic patients is associated with development of hepatocellular carcinoma Int. J. Cancer 2006, 119, 735-740
22. Cigliano, L.; Pugliese, C. R.; Spagnuolo, M. S.; Palumbo, R.; Abrescia, P. Haptoglobin binds the antiatherogenic protein apolipoprotein E-impairment of apolipoprotein E stimulation of both lecithin:cholesterol acyltransferase activity and cholesterol uptake by hepatocytes FEBS J. 2009, 276, 6158-6171
23. Okemefuna, A. I.; Li, K.; Nan, R.; Ormsby, R. J.; Sadlon, T.; Gordon, D. L.; Perkins, S. J. Multimeric interactions between complement factor H and its C3d ligand provide new insight on complement regulation J. Mol. Biol. 2009, 391, 119-135
24. Jelezarova, E.; Vogt, A.; Lutz, H. U. Interaction of C3b(2)-IgG complexes with complement proteins properdin, factor B and factor H: implications for amplification Biochem. J. 2000, 349, 217-223
25. Abdullah, M.; Schultz, H.; Kahler, D.; Branscheid, D.; Dalhoff, K.; Zabel, P.; Vollmer, E.; Goldmann, T. Expression of the acute phase protein haptoglobin in human lung cancer and tumor-free lung tissues Pathol. Res. Pract. 2009, 205, 639-647
26. Dunkelberger, J. R.; Song, W. C. Complement and its role in innate and adaptive immune responses Cell Res. 2010, 20, 34-50
27. Pio, R.; Garcia, J.; Corrales, L.; Ajona, D.; Fleischhacker, M.; Pajares, M. J.; Cardenal, F.; Seijo, L.; Zulueta, J. J.; Nadal, E.; Witt, C.; Lozano, M. D.; Schmidt, B.; Montuenga, L. M. Complement factor H is elevated in bronchoalveolar lavage fluid and sputum from patients with lung cancer Cancer Epidemiol. Biomarkers Prev. 2010, 19, 2665-2672
28. Wilczek, E.; Rzepko, R.; Nowis, D.; Legat, M.; Golab, J.; Glab, M.; Gorlewicz, A.; Konopacki, F.; Mazurkiewicz, M.; Sladowski, D.; Gornicka, B.; Wasiutynski, A.; Wilczynski, G. M. The possible role of factor H in colon cancer resistance to complement attack Int. J. Cancer 2008, 122, 2030-2037
29. Pouns, O.; Mangas, A.; Covenas, R.; Geffard, M. Circulating antibodies directed against "polycyclic aromatic hydrocarbon-like" structures in the sera of cancer patients Cancer Epidemiol. 2009, 33, 3-8
30. Ehmann, M.; Felix, K.; Hartmann, D.; Schnolzer, M.; Nees, M.; Vorderwulbecke, S.; Bogumil, R.; Buchler, M. W.; Friess, H. Identification of potential markers for the detection of pancreatic cancer through comparative serum protein expression profiling Pancreas 2007, 34, 205-214
31. Engwegen, J. Y.; Helgason, H. H.; Cats, A.; Harris, N.; Bonfrer, J. M.; Schellens, J. H.; Beijnen, J. H. Identification of serum proteins discriminating colorectal cancer patients and healthy controls using surface-enhanced laser desorption ionisation-time of flight mass spectrometry World J. Gastroenterol. 2006, 12, 1536-1544