Monocytic suppressor cells derived from human peripheral blood suppress xenogenic immune reactions

Xenotransplantation

Volumn 21, Issue 1, 2014, Pages 46-56

  Maeda, Akira ^a   Kawamura, Takuji ^a   Ueno, Takehisa ^a   Usui, Noriaki ^a   Miyagawa, Shuji ^a  

^a OSAKA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

indoleamine 2 3 dioxygenase; myeloid derived suppressor cells; xenogenic immune reactions; xenotransplantation

Indexed keywords

ADAPTIVE IMMUNITY; ANIMAL; CELL LINE; DENDRITIC CELL; GRAFT REJECTION; HUMAN; IMMUNOLOGY; MONOCYTE; MONONUCLEAR CELL; XENOGRAFT;

ADAPTIVE IMMUNITY; ANIMALS; CELL LINE; DENDRITIC CELLS; GRAFT REJECTION; HUMANS; LEUKOCYTES, MONONUCLEAR; MONOCYTES; TRANSPLANTATION, HETEROLOGOUS;

EID: 84893842676     PISSN: 0908665X     EISSN: 13993089     Source Type: Journal    
DOI: 10.1111/xen.12067     Document Type: Article

References (30)

1. Phelps CJ, Koike C, Vaught TD, et al. Production of alpha 1,3-galactosyltransferase-deficient pigs. Science 2003; 299: 411-414.
2. Takahagi Y, Fujimura T, Miyagawa S, et al. Production of alpha 1,3-galactosyltransferase gene knockout pigs expressing both human decay-accelerating factor and N-acetylglucosaminyltransferase III. Mol Reprod Dev 2005; 71: 331-338. (Pubitemid 40770387)
3. Baumann BC, Stussi G, Huggel K, Rieben R, Seebach JD,. Reactivity of human natural antibodies to endothelial cells from Galalpha(1,3)Gal-deficient pigs. Transplantation 2007; 83: 193-201. (Pubitemid 46185210)
4. Fujimura T, Takahagi Y, Shigehisa T, et al. Production of alpha 1,3-galactosyltransferase gene-deficient pigs by somatic cell nuclear transfer: a novel selection method for gal alpha 1,3-Gal antigen-deficient cells. Mol Reprod Dev 2008; 75: 1372-1378. (Pubitemid 352032525)
5. Almand B, Clark JI, Nikitina E, et al. Production of immature myeloid cells in cancer patients: a mechanism of immunosuppression in cancer. J Immunol 2001; 166: 678-689. (Pubitemid 32038493)
6. Bronte V, Apolloni E, Cabrelle A, et al. Identification of a CD11b(+)/Gr-1(+)/CD31(+) myeloid progenitor capable of activating or suppressing CD8(+) T cells. Blood 2000; 96: 3838-3846.
7. Mandruzzato S, Solito S, Falisi E, et al. IL4Ralpha+ myeloid-derived suppressor cell expansion in cancer patients. J Immunol 2009; 182: 6562-6568.
8. Movahed K, Guilliams M, Van den Bossche J, et al. Identification of discrete tumor-induced myeloid-derived suppressor cell subpopulations with distinct T cell-suppressive activity. Blood 2008; 111: 4233-4244.
9. Youn JI, Nagaraj S, Collazo M, Gabrilovich DI,. Subsets of myeloid-derived suppressor cells in tumor-bearing mice. J Immunol 2008; 181: 5791-5802.
10. Dugast AS, Haudebourg T, Coulon F, et al. Myeloid-derived suppressor cells accumulate in kidney allograft tolerance and specifically suppress effector T cell expansion. J Immunol 2008; 180: 7898-7906.
11. Ghansah T, Paraiso KH, Highfill S, et al. Expansion of myeloid suppressor cells in SHIP-deficient mice represses allogeneic T cell responses. J Immunol 2004; 173: 7324-7330. (Pubitemid 39628170)
12. Paraiso KH, Ghansah T, Costello A, Engelman RW, Kerr WG,. Induced SHIP deficiency expands myeloid regulatory cells and abrogates graft-versus-host disease. J Immunol 2007; 178: 2893-2900. (Pubitemid 46333167)
13. Highfill SL, Rodriguez PC, Zhou Q, et al. Bone marrow myeloid-derived suppressor cells (MDSCs) inhibit graft-versus-host disease (GVHD) via an arginase-1-dependent mechanism that is up-regulated by interleukin-13. Blood 2010; 116: 5738-5747.
14. Liu Q, Sasaki T, Kozieradzki I, et al. SHIP is a negative regulator of growth factor receptor-mediated PKB/Akt activation and myeloid cell survival. Genes Dev 1999; 13: 786-791. (Pubitemid 29169837)
15. Zhou Z, French DL, Ma G, et al. Development and function of myeloid-derived suppressor cells generated from mouse embryonic and hematopoietic stem cells. Stem Cells 2010; 28: 620-632.
16. De Wilde V, Van Rompaey N, Hill M, et al. Endotoxin-induced myeloid-derived suppressor cells inhibit alloimmune responses via heme oxygenase-1. Am J Transplant 2009; 9: 2034-2047.
17. Adeegbe D, Matsutani T, Yang J, Altman NH, Malek TR,. CD4(+) CD25(+) Foxp3(+) T regulatory cells with limited TCR diversity in control of autoimmunity. J Immunol 2010; 184: 56-66.
18. Garcia MR, Ledgerwood L, Yang Y, et al. Monocytic suppressive cells mediate cardiovascular transplantation tolerance in mice. J Clin Invest 2010; 120: 2486-2496.
19. Zhang W, Liang S, Wu J, Horuzsko A,. Human inhibitory receptor immunoglobulin-like transcript 2 amplifies CD11b+ Gr1+ myeloid-derived suppressor cells that promote long-term survival of allografts. Transplantation 2008; 86: 1125-1134.
20. Marigo I, Bosio E, Solito S, et al. Tumor-induced tolerance and immune suppression depend on the C/EBPbeta transcription factor. Immunity 2010; 32: 790-802.
21. Hock BD, Mackenzie KA, Cross NB, et al. Renal transplant recipients have elevated frequencies of circulating myeloid-derived suppressor cells. Nephrol Dial Transplant 2012; 27: 402-410.
22. Mellor AL, Munn DH,. IDO expression by dendritic cells: tolerance and tryptophan catabolism. Nat Rev Immunol 2004; 4: 762-774. (Pubitemid 39336293)
23. Grohmann U, Fallarino F, Puccetti P,. Tolerance, DCs and tryptophan: much ado about IDO. Trends Immunol 2003; 24: 242-248. (Pubitemid 36555962)
24. Kawamoto K, Tanemura M, Nishida T, et al. Significant inhibition of Human CD8+ cytotoxic T lymphocyte-mediated xenocytotoxicity by overexpression of the human decoy Fas antigen. Transplantation 2006; 81: 789-796.
25. Chou HS, Hsieh CC, Charles R, et al. Myeloid-derived suppressor cells protect islet transplants by B7-H1 mediated enhancement of T regulatory cells. Transplantation 2012; 93: 272-282.
26. Bogdan C,. Regulation of lymphocytes by nitric oxide. Methods Mol Biol 2011; 677: 375-393.
27. Schmielau J, Finn OJ,. Activated granulocytes and granulocyte-derived hydrogen peroxide are the underlying mechanism of suppression of t-cell function in advanced cancer patients. Cancer Res 2001; 61: 4756-4760. (Pubitemid 32691887)
28. Zea AH, Rodriguez PC, Atkins MB, et al. Arginase-producing myeloid suppressor cells in renal cell carcinoma patients: a mechanism of tumor evasion. Cancer Res 2005; 65: 3044-3048. (Pubitemid 40524582)
29. Poschke I, Mougiakakos D, Hansson J, Masucci GV, Kiessling R,. Immature Immunosuppressive CD14+ HLA-DR-/low Cells in Melanoma Patients are Stat3hi and Overexpress CD80, CD83, and DC-Sign. Cancer Res 2010; 70: 4335-4345.
30. Obermajer N, Wong JL, Edwards RP, et al. PGE(2)-driven induction and maintenance of cancer-associated myeloid-derived suppressor cells. Immunol Invest 2012; 41: 635-657.