Inhibition of extracellular HMGB1 attenuates hyperoxia-induced inflammatory acute lung injury

Redox Biology

Volumn 2, Issue 1, 2014, Pages 314-322

  Entezari, Maria ^a,b,c   Javdan, Mohammad ^a,b,c   Antoine, Daniel J ^d   Morrow, Dympna M P ^a,b   Sitapara, Ravikumar A ^a   Patel, Vivek ^a   Wang, Mao ^a   Sharma, Lokesh ^a   Gorasiya, Samir ^a   Zur, Michelle ^a   Wu, Wenjun ^a   Li, JianHua ^a   Yang, Huan ^b   Ashby, Charles R ^a   Thomas, Douglas ^e   Wang, Haichao ^b   Mantell, Lin L ^a,b  

^a ST JOHN'S UNIVERSITY   (United States)

^b FEINSTEIN INSTITUTE FOR MEDICAL RESEARCH   (United States)

^c CITY UNIVERSITY OF NEW YORK   (United States)

^d UNIVERSITY OF LIVERPOOL   (United Kingdom)

^e UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

Author keywords

HMGB1; Hyperacetylation; Hyperoxia; Macrophage; Redox state

Indexed keywords

ETHYL PYRUVIC ACID; HIGH MOBILITY GROUP B1 PROTEIN; NEUTRALIZING ANTIBODY; PYRUVIC ACID; UNCLASSIFIED DRUG; ANTIOXIDANT; ETHYL PYRUVATE; PROTEIN ANTIBODY; RECOMBINANT HIGH MOBILITY GROUP B1 PROTEIN; RECOMBINANT PROTEIN; ANTIBODY; HMGB1 PROTEIN, MOUSE; PYRUVIC ACID DERIVATIVE;

ACETYLATION; ACUTE LUNG INJURY; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIOXIDANT ACTIVITY; ARTICLE; ARTIFICIAL VENTILATION; CONTROLLED STUDY; DRY WEIGHT; HISTOPATHOLOGY; HYPEROXIA; INFLAMMATORY ACUTE LUNG INJURY; INFLAMMATORY DISEASE; LEUKOCYTE; LEUKOCYTE COUNT; LIQUID CHROMATOGRAPHY; LUNG EDEMA; LUNG LAVAGE; LYMPHOCYTIC INFILTRATION; MOUSE; NEUTROPHIL CHEMOTAXIS; NONHUMAN; OXIDATION REDUCTION STATE; PRIORITY JOURNAL; PROTEIN CONTENT; PROTEIN SECRETION; TANDEM MASS SPECTROMETRY; ADULT; ANALYTICAL PARAMETERS; ANIMAL TISSUE; CELL INFILTRATION; DISEASE SEVERITY; DRUG MECHANISM; EXTRACELLULAR SPACE; IMMUNOHISTOCHEMISTRY; MOUSE MODEL; OXIDATION; PNEUMONIA; PROTECTION; PROTEIN ACETYLATION; PROTEIN AGGREGATION; PROTEIN ANALYSIS; WET DRY WEIGHT RATIO; ANIMAL; ANTAGONISTS AND INHIBITORS; C57BL MOUSE; CELL HYPOXIA; CELL LINE; CHEMICALLY INDUCED; CYTOLOGY; DISEASE MODEL; IMMUNOLOGY; INTRASPINAL DRUG ADMINISTRATION; LUNG; MALE; METABOLISM; NEUTROPHIL; PATHOLOGY;

ACETYLATION; ACUTE LUNG INJURY; ANIMALS; ANTIBODIES; BRONCHOALVEOLAR LAVAGE FLUID; CELL HYPOXIA; CELL LINE; DISEASE MODELS, ANIMAL; HMGB1 PROTEIN; INJECTIONS, SPINAL; LUNG; MALE; MICE; MICE, INBRED C57BL; NEUTROPHILS; PYRUVATES;

EID: 84893824735     PISSN: 22132317     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.redox.2014.01.013     Document Type: Article

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