-
1
-
-
33749488939
-
Human multidrug resistance ABCB and ABCG transporters: Participation in a chemoimmunity defense system
-
DOI 10.1152/physrev.00037.2005
-
B. Sarkadi, L. Homolya, G. Szakács, and A. Váradi Human multidrug resistance ABCB and ABCG transporters: participation in a chemoimmunity defense system Physiol. Rev. 86 2006 1179 1236 (Pubitemid 44521651)
-
(2006)
Physiological Reviews
, vol.86
, Issue.4
, pp. 1179-1236
-
-
Sarkadi, B.1
Homolya, L.2
Szakacs, G.3
Varadi, A.4
-
2
-
-
79956326438
-
Transporter-mediated drug uptake and efflux: Important determinants of adverse drug reaction
-
O. Zolk, and M.F. Fromm Transporter-mediated drug uptake and efflux: important determinants of adverse drug reaction Clin. Pharmacol. Ther. 89 2011 798 805
-
(2011)
Clin. Pharmacol. Ther.
, vol.89
, pp. 798-805
-
-
Zolk, O.1
Fromm, M.F.2
-
3
-
-
17544368685
-
Multidrug resistance proteins: Role of P-glycoprotein, MRP1, MRP2, and BCRP (ABCG2) in tissue defense
-
DOI 10.1016/j.taap.2004.10.012, Membrane Transporters in Toxicology
-
E.M. Leslie, R.G. Deeley, and S.P. Cole Multidrug resistance proteins: role of P-glycoprotein, MRP1, MRP2, and BCRP (ABCG2) in tissue defense Toxicol. Appl. Pharmacol. 204 2005 216 237 (Pubitemid 40552845)
-
(2005)
Toxicology and Applied Pharmacology
, vol.204
, Issue.3
, pp. 216-237
-
-
Leslie, E.M.1
Deeley, R.G.2
Cole, S.P.C.3
-
4
-
-
79953803082
-
ATP-binding cassette efflux transporters in human placenta
-
Z. Ni, and Q. Mao ATP-binding cassette efflux transporters in human placenta Curr. Pharm. Biotechnol. 12 2011 674 685
-
(2011)
Curr. Pharm. Biotechnol.
, vol.12
, pp. 674-685
-
-
Ni, Z.1
Mao, Q.2
-
5
-
-
0032404092
-
A human placenta-specific ATP-binding cassette gene (ABCP) on chromosome 4q22 that is involved in multidrug resistance
-
R. Allikmets, L.M. Schriml, A. Hutchinson, V. Romano-Spica, and M. Dean A human placenta-specific ATP-binding cassette gene (ABCP) on chromosome 4q22 that is involved in multidrug resistance Cancer Res. 58 1998 5337 5339 (Pubitemid 28551112)
-
(1998)
Cancer Research
, vol.58
, Issue.23
, pp. 5337-5339
-
-
Allikmets, R.1
Schriml, L.M.2
Hutchinson, A.3
Romano-Spica, V.4
Dean, M.5
-
6
-
-
84885972386
-
Molecular pharmacology of ABCG2 and its role in chemoresistance
-
A.E. Stacy, P.J. Jansson, and D.R. Richardson Molecular pharmacology of ABCG2 and its role in chemoresistance Mol. Pharmacol. 84 2013 655 669
-
(2013)
Mol. Pharmacol.
, vol.84
, pp. 655-669
-
-
Stacy, A.E.1
Jansson, P.J.2
Richardson, D.R.3
-
7
-
-
67649886415
-
Identification of a urate transporter, ABCG2, with a common functional polymorphism causing gout
-
O.M. Woodward, A. Köttgen, J. Coresh, E. Boerwinkle, W.B. Guggino, and M. Köttgen Identification of a urate transporter, ABCG2, with a common functional polymorphism causing gout Proc. Natl. Acad. Sci. U.S.A. 106 2013 10338 10342
-
(2013)
Proc. Natl. Acad. Sci. U.S.A.
, vol.106
, pp. 10338-10342
-
-
Woodward, O.M.1
Köttgen, A.2
Coresh, J.3
Boerwinkle, E.4
Guggino, W.B.5
Köttgen, M.6
-
8
-
-
84867570442
-
Polymorphisms to predict outcome to the tyrosine kinase inhibitors gefitinib, erlotinib, sorafenib and sunitinib
-
L. Erdem, E. Giovannetti, L.G. Leon, R. Honeywell, and G.J. Peters Polymorphisms to predict outcome to the tyrosine kinase inhibitors gefitinib, erlotinib, sorafenib and sunitinib Curr. Top. Med. Chem. 12 2012 1649 1659
-
(2012)
Curr. Top. Med. Chem.
, vol.12
, pp. 1649-1659
-
-
Erdem, L.1
Giovannetti, E.2
Leon, L.G.3
Honeywell, R.4
Peters, G.J.5
-
9
-
-
84857768340
-
Functional significance of genetic polymorphisms in P-glycoprotein (MDR1, ABCB1) and breast cancer resistance protein (BCRP, ABCG2)
-
I. Ieiri Functional significance of genetic polymorphisms in P-glycoprotein (MDR1, ABCB1) and breast cancer resistance protein (BCRP, ABCG2) Drug Metab. Pharmacokinet. 27 2012 85 105
-
(2012)
Drug Metab. Pharmacokinet.
, vol.27
, pp. 85-105
-
-
Ieiri, I.1
-
11
-
-
77951031222
-
Interaction of angiotensin receptor type 1 blockers with ATP-binding cassette transporters
-
J. Weiss, A. Sauer, N. Divac, M. Herzog, E. Schwedhelm, R.H. Böger, W.E. Haefeli, and R.A. Benndorf Interaction of angiotensin receptor type 1 blockers with ATP-binding cassette transporters Biopharm. Drug Dispos. 31 2010 150 161
-
(2010)
Biopharm. Drug Dispos.
, vol.31
, pp. 150-161
-
-
Weiss, J.1
Sauer, A.2
Divac, N.3
Herzog, M.4
Schwedhelm, E.5
Böger, R.H.6
Haefeli, W.E.7
Benndorf, R.A.8
-
12
-
-
70349264523
-
Interaction of thiazolidinediones (glitazones) with the ATP-binding cassette transporters P-glycoprotein and breast cancer resistance protein
-
J. Weiss, A. Sauer, M. Herzog, R.H. Böger, W.E. Haefeli, and R.A. Benndorf Interaction of thiazolidinediones (glitazones) with the ATP-binding cassette transporters P-glycoprotein and breast cancer resistance protein Pharmacology 84 2009 264 270
-
(2009)
Pharmacology
, vol.84
, pp. 264-270
-
-
Weiss, J.1
Sauer, A.2
Herzog, M.3
Böger, R.H.4
Haefeli, W.E.5
Benndorf, R.A.6
-
13
-
-
55449120824
-
Isoprostanes inhibit vascular endothelial growth factor-induced endothelial cell migration, tube formation, and cardiac vessel sprouting in vitro, as well as angiogenesis in vivo via activation of the thromboxane A(2) receptor: A potential link between oxidative stress and impaired angiogenesis
-
R.A. Benndorf, E. Schwedhelm, A. Gnann, R. Taheri, G. Kom, M. Didié, A. Steenpass, S. Ergün, and R.H. Böger Isoprostanes inhibit vascular endothelial growth factor-induced endothelial cell migration, tube formation, and cardiac vessel sprouting in vitro, as well as angiogenesis in vivo via activation of the thromboxane A(2) receptor: a potential link between oxidative stress and impaired angiogenesis Circ. Res. 103 2008 1037 1046
-
(2008)
Circ. Res.
, vol.103
, pp. 1037-1046
-
-
Benndorf, R.A.1
Schwedhelm, E.2
Gnann, A.3
Taheri, R.4
Kom, G.5
Didié, M.6
Steenpass, A.7
Ergün, S.8
Böger, R.H.9
-
14
-
-
67349153054
-
Angiotensin II type 2 receptor deficiency aggravates renal injury and reduces survival in chronic kidney disease in mice
-
R.A. Benndorf, C. Krebs, B. Hirsch-Hoffmann, E. Schwedhelm, G. Cieslar, R. Schmidt-Haupt, O.M. Steinmetz, C. Meyer-Schwesinger, F. Thaiss, M. Haddad, S. Fehr, A. Heilmann, U. Helmchen, L. Hein, H. Ehmke, R.A. Stahl, R.H. Böger, and U.O. Wenzel Angiotensin II type 2 receptor deficiency aggravates renal injury and reduces survival in chronic kidney disease in mice Kidney Int. 75 2009 1039 1049
-
(2009)
Kidney Int.
, vol.75
, pp. 1039-1049
-
-
Benndorf, R.A.1
Krebs, C.2
Hirsch-Hoffmann, B.3
Schwedhelm, E.4
Cieslar, G.5
Schmidt-Haupt, R.6
Steinmetz, O.M.7
Meyer-Schwesinger, C.8
Thaiss, F.9
Haddad, M.10
Fehr, S.11
Heilmann, A.12
Helmchen, U.13
Hein, L.14
Ehmke, H.15
Stahl, R.A.16
Böger, R.H.17
Wenzel, U.O.18
-
15
-
-
84868152458
-
Impact of AT2 receptor deficiency on postnatal cardiovascular development
-
D. Biermann, A. Heilmann, M. Didié, S. Schlossarek, A. Wahab, M. Grimm, M. Römer, H. Reichenspurner, K.R. Sultan, A. Steenpass, S. Ergün, S. Donzelli, L. Carrier, H. Ehmke, W.H. Zimmermann, L. Hein, R.H. Böger, and R.A. Benndorf Impact of AT2 receptor deficiency on postnatal cardiovascular development PLoS ONE 7 2012 e47916
-
(2012)
PLoS ONE
, vol.7
, pp. 47916
-
-
Biermann, D.1
Heilmann, A.2
Didié, M.3
Schlossarek, S.4
Wahab, A.5
Grimm, M.6
Römer, M.7
Reichenspurner, H.8
Sultan, K.R.9
Steenpass, A.10
Ergün, S.11
Donzelli, S.12
Carrier, L.13
Ehmke, H.14
Zimmermann, W.H.15
Hein, L.16
Böger, R.H.17
Benndorf, R.A.18
-
16
-
-
2442451618
-
Angiotensin type 1 receptor blockers induce peroxisome proliferator-activated receptor-γ activity
-
DOI 10.1161/01.CIR.0000127955.36250.65
-
M. Schupp, J. Janke, R. Clasen, T. Unger, and U. Kintscher Angiotensin type 1 receptor blockers induce peroxisome proliferator-activated receptor-gamma activity Circulation 109 2004 2054 2057 (Pubitemid 38620211)
-
(2004)
Circulation
, vol.109
, Issue.17
, pp. 2054-2057
-
-
Schupp, M.1
Janke, J.2
Clasen, R.3
Unger, T.4
Kintscher, U.5
-
17
-
-
33747131444
-
Telmisartan improves insulin sensitivity in nondiabetic patients with essential hypertension
-
DOI 10.1016/j.metabol.2006.04.013, PII S0026049506001557
-
R.A. Benndorf, T. Rudolph, D. Appel, E. Schwedhelm, R. Maas, F. Schulze, E. Silberhorn, and R.H. Böger Telmisartan improves insulin sensitivity in nondiabetic patients with essential hypertension Metabolism 55 2006 1159 1164 (Pubitemid 44219053)
-
(2006)
Metabolism: Clinical and Experimental
, vol.55
, Issue.9
, pp. 1159-1164
-
-
Benndorf, R.A.1
Rudolph, T.2
Appel, D.3
Schwedhelm, E.4
Maas, R.5
Schulze, F.6
Silberhorn, E.7
Boger, R.H.8
-
18
-
-
33847125757
-
Pharmacokinetics of oral doses of telmisartan and nisoldipine, given alone and in combination, in patients with essential hypertension
-
DOI 10.1177/0091270006297225
-
M. Bajcetic, R.A. Benndorf, D. Appel, E. Schwedhelm, F. Schulze, D. Riekhof, R. Maas, and R.H. Böger Pharmacokinetics of oral doses of telmisartan and nisoldipine, given alone and in combination, in patients with essential hypertension J. Clin. Pharmacol. 47 2007 295 304 (Pubitemid 46294712)
-
(2007)
Journal of Clinical Pharmacology
, vol.47
, Issue.3
, pp. 295-304
-
-
Bajcetic, M.1
Benndorf, R.A.2
Appel, D.3
Schwedhelm, E.4
Schulze, F.5
Riekhof, D.6
Maas, R.7
Boger, R.H.8
-
19
-
-
33745286306
-
Functional validation of the genetic polymorphisms of human ATP-binding cassette (ABC) transporter ABCG2: Identification of alleles that are defective in porphyrin transport
-
A. Tamura, M. Watanabe, H. Saito, H. Nakagawa, T. Kamachi, I. Okura, and T. Ishikawa Functional validation of the genetic polymorphisms of human ATP-binding cassette (ABC) transporter ABCG2: identification of alleles that are defective in porphyrin transport Mol. Pharmacol. 70 2006 287 296
-
(2006)
Mol. Pharmacol.
, vol.70
, pp. 287-296
-
-
Tamura, A.1
Watanabe, M.2
Saito, H.3
Nakagawa, H.4
Kamachi, T.5
Okura, I.6
Ishikawa, T.7
-
20
-
-
84880506420
-
Effects of the gout-causing Q141K polymorphism and a CFTR Δf508 mimicking mutation on the processing and stability of the ABCG2 protein
-
H. Sarankó, H. Tordai, Á. Telbisz, C. Özvegy-Laczka, G. Erdos, B. Sarkadi, and T. Hegedus Effects of the gout-causing Q141K polymorphism and a CFTR ΔF508 mimicking mutation on the processing and stability of the ABCG2 protein Biochem. Biophys. Res. Commun. 437 2013 140 145
-
(2013)
Biochem. Biophys. Res. Commun.
, vol.437
, pp. 140-145
-
-
Sarankó, H.1
Tordai, H.2
Telbisz, Á.3
Özvegy-Laczka, C.4
Erdos, G.5
Sarkadi, B.6
Hegedus, T.7
-
21
-
-
57049083981
-
Association of three genetic loci with uric acid concentration and risk of gout: A genome-wide association study
-
A. Dehghan, A. Köttgen, Q. Yang, S.J. Hwang, W.L. Kao, F. Rivadeneira, E. Boerwinkle, D. Levy, A. Hofman, B.C. Astor, E.J. Benjamin, C.M. van Duijn, J.C. Witteman, J. Coresh, and C.S. Fox Association of three genetic loci with uric acid concentration and risk of gout: a genome-wide association study Lancet 372 2008 1953 1961
-
(2008)
Lancet
, vol.372
, pp. 1953-1961
-
-
Dehghan, A.1
Köttgen, A.2
Yang, Q.3
Hwang, S.J.4
Kao, W.L.5
Rivadeneira, F.6
Boerwinkle, E.7
Levy, D.8
Hofman, A.9
Astor, B.C.10
Benjamin, E.J.11
Van Duijn, C.M.12
Witteman, J.C.13
Coresh, J.14
Fox, C.S.15
-
22
-
-
48749090651
-
Human ABC transporters ABCG2 (BCRP) and ABCG4
-
S. Koshiba, R. An, H. Saito, T. Wakabayashi, A. Tamura, and T. Ishikawa Human ABC transporters ABCG2 (BCRP) and ABCG4 Xenobiotica 38 2008 863 888
-
(2008)
Xenobiotica
, vol.38
, pp. 863-888
-
-
Koshiba, S.1
An, R.2
Saito, H.3
Wakabayashi, T.4
Tamura, A.5
Ishikawa, T.6
-
23
-
-
34249080047
-
The identification of two germ-line mutations in the human breast cancer resistance protein gene that result in the expression of a low/non-functional protein
-
DOI 10.1007/s11095-007-9235-2
-
S. Yoshioka, K. Katayama, C. Okawa, S. Takahashi, S. Tsukahara, J. Mitsuhashi, and Y. Sugimoto The identification of two germ-line mutations in the human breast cancer resistance protein gene that result in the expression of a low/non-functional protein Pharm. Res. 24 2007 1108 1117 (Pubitemid 46798890)
-
(2007)
Pharmaceutical Research
, vol.24
, Issue.6
, pp. 1108-1117
-
-
Yoshioka, S.1
Katayama, K.2
Okawa, C.3
Takahashi, S.4
Tsukahara, S.5
Mitsuhashi, J.6
Sugimoto, Y.7
-
24
-
-
0042354831
-
Transport of methotrexate, methotrexate polyglutamates, and 17β-estradiol 17-(β-D-glucuronide) by ABCG2: Effects of acquired mutations at R482 on methotrexate transport
-
Z.S. Chen, R.W. Robey, M.G. Belinsky, I. Shchaveleva, X.Q. Ren, Y. Sugimoto, D.D. Ross, S.E. Bates, and G.D. Kruh Transport of methotrexate, methotrexate polyglutamates, and 17beta-estradiol 17-(beta-D-glucuronide) by ABCG2: effects of acquired mutations at R482 on methotrexate transport Cancer Res. 63 2003 4048 4054 (Pubitemid 36917926)
-
(2003)
Cancer Research
, vol.63
, Issue.14
, pp. 4048-4054
-
-
Chen, Z.-S.1
Robey, R.W.2
Belinsky, M.G.3
Shchaveleva, I.4
Ren, X.-Q.5
Sugimoto, Y.6
Ross, D.D.7
Bates, S.E.8
Kruh, G.D.9
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