-
1
-
-
80054801048
-
Treating Mycobacterium ulcerans disease (Buruli ulcer): from surgery to antibiotics, is the pill mightier than the knife?
-
Converse PJ, Nuermberger EL, Almeida DV, Grosset JH, (2011) Treating Mycobacterium ulcerans disease (Buruli ulcer): from surgery to antibiotics, is the pill mightier than the knife? Future Microbiology 6: 1185-1198.
-
(2011)
Future Microbiology
, vol.6
, pp. 1185-1198
-
-
Converse, P.J.1
Nuermberger, E.L.2
Almeida, D.V.3
Grosset, J.H.4
-
2
-
-
0033524996
-
Mycolactone: a polyketide toxin from Mycobacterium ulcerans required for virulence
-
George KM, Chatterjee D, Gunawardana G, Welty D, Hayman J, et al. (1999) Mycolactone: a polyketide toxin from Mycobacterium ulcerans required for virulence. Science 283: 854-857.
-
(1999)
Science
, vol.283
, pp. 854-857
-
-
George, K.M.1
Chatterjee, D.2
Gunawardana, G.3
Welty, D.4
Hayman, J.5
-
3
-
-
10744229306
-
Giant plasmid-encoded polyketide synthases produce the macrolide toxin of Mycobacterium ulcerans
-
Stinear TP, Mve-Obiang A, Small PL, Frigui W, Pryor MJ, et al. (2004) Giant plasmid-encoded polyketide synthases produce the macrolide toxin of Mycobacterium ulcerans. Proc Natl Acad Sci U S A 101: 1345-1349.
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 1345-1349
-
-
Stinear, T.P.1
Mve-Obiang, A.2
Small, P.L.3
Frigui, W.4
Pryor, M.J.5
-
4
-
-
0001148119
-
The pathogenic behavior of Mycobacterium ulcerans and Mycobacterium balnei in the mouse and the developing chick embryo
-
Fenner F, (1956) The pathogenic behavior of Mycobacterium ulcerans and Mycobacterium balnei in the mouse and the developing chick embryo. Am Rev Tuberc 73: 650-673.
-
(1956)
Am Rev Tuberc
, vol.73
, pp. 650-673
-
-
Fenner, F.1
-
5
-
-
0034770057
-
Activities of new macrolides and fluoroquinolones against Mycobacterium ulcerans infection in mice
-
Bentoucha A, Robert J, Dega H, Lounis N, Jarlier V, et al. (2001) Activities of new macrolides and fluoroquinolones against Mycobacterium ulcerans infection in mice. Antimicrob Agents Chemother 45: 3109-3112.
-
(2001)
Antimicrob Agents Chemother
, vol.45
, pp. 3109-3112
-
-
Bentoucha, A.1
Robert, J.2
Dega, H.3
Lounis, N.4
Jarlier, V.5
-
6
-
-
0036783676
-
Bactericidal activity of rifampin-amikacin against Mycobacterium ulcerans in mice
-
Dega H, Bentoucha A, Robert J, Jarlier V, Grosset J, (2002) Bactericidal activity of rifampin-amikacin against Mycobacterium ulcerans in mice. Antimicrob Agents Chemother 46: 3193-3196.
-
(2002)
Antimicrob Agents Chemother
, vol.46
, pp. 3193-3196
-
-
Dega, H.1
Bentoucha, A.2
Robert, J.3
Jarlier, V.4
Grosset, J.5
-
7
-
-
0033844507
-
Activities of several antimicrobials against Mycobacterium ulcerans infection in mice
-
Dega H, Robert J, Bonnafous P, Jarlier V, Grosset J, (2000) Activities of several antimicrobials against Mycobacterium ulcerans infection in mice. Antimicrob Agents Chemother 44: 2367-2372.
-
(2000)
Antimicrob Agents Chemother
, vol.44
, pp. 2367-2372
-
-
Dega, H.1
Robert, J.2
Bonnafous, P.3
Jarlier, V.4
Grosset, J.5
-
8
-
-
35848932800
-
Promising clinical efficacy of streptomycin-rifampin combination for treatment of Buruli Ulcer (Mycobacterium ulcerans Disease)
-
Chauty A, Ardant M-F, Adeye A, Euverte H, Guedenon A, et al. (2007) Promising clinical efficacy of streptomycin-rifampin combination for treatment of Buruli Ulcer (Mycobacterium ulcerans Disease). Antimicrob Agents Chemother 51: 4029-4035.
-
(2007)
Antimicrob Agents Chemother
, vol.51
, pp. 4029-4035
-
-
Chauty, A.1
Ardant, M.-F.2
Adeye, A.3
Euverte, H.4
Guedenon, A.5
-
9
-
-
23044451316
-
Efficacy of the Combination Rifampin-Streptomycin in Preventing Growth of Mycobacterium ulcerans in Early Lesions of Buruli Ulcer in Humans
-
Etuaful S, Carbonnelle B, Grosset J, Lucas S, Horsfield C, et al. (2005) Efficacy of the Combination Rifampin-Streptomycin in Preventing Growth of Mycobacterium ulcerans in Early Lesions of Buruli Ulcer in Humans. Antimicrob Agents Chemother 49: 3182-3186.
-
(2005)
Antimicrob Agents Chemother
, vol.49
, pp. 3182-3186
-
-
Etuaful, S.1
Carbonnelle, B.2
Grosset, J.3
Lucas, S.4
Horsfield, C.5
-
10
-
-
77049112710
-
Antimicrobial treatment for early, limited Mycobacterium ulcerans infection: a randomised controlled trial
-
Nienhuis WA, Stienstra Y, Thompson WA, Awuah PC, Abass KM, et al. (2010) Antimicrobial treatment for early, limited Mycobacterium ulcerans infection: a randomised controlled trial. The Lancet 375: 664-672.
-
(2010)
The Lancet
, vol.375
, pp. 664-672
-
-
Nienhuis, W.A.1
Stienstra, Y.2
Thompson, W.A.3
Awuah, P.C.4
Abass, K.M.5
-
11
-
-
77956129001
-
Clinical efficacy of combination of rifampin and streptomycin for treatment of Mycobacterium ulcerans disease
-
Sarfo FS, Phillips R, Asiedu K, Ampadu E, Bobi N, et al. (2010) Clinical efficacy of combination of rifampin and streptomycin for treatment of Mycobacterium ulcerans disease. Antimicrob Agents Chemother 54: 3678-3685.
-
(2010)
Antimicrob Agents Chemother
, vol.54
, pp. 3678-3685
-
-
Sarfo, F.S.1
Phillips, R.2
Asiedu, K.3
Ampadu, E.4
Bobi, N.5
-
12
-
-
0033979230
-
A Mycobacterium ulcerans toxin, mycolactone, causes apoptosis in guinea pig ulcers and tissue culture cells
-
George KM, Pascopella L, Welty DM, Small PL, (2000) A Mycobacterium ulcerans toxin, mycolactone, causes apoptosis in guinea pig ulcers and tissue culture cells. Infect Immun 68: 877-883.
-
(2000)
Infect Immun
, vol.68
, pp. 877-883
-
-
George, K.M.1
Pascopella, L.2
Welty, D.M.3
Small, P.L.4
-
13
-
-
44249084709
-
Mycolactones: immunosuppressive and cytotoxic polyketides produced by aquatic mycobacteria
-
Hong H, Demangel C, Pidot SJ, Leadlay PF, Stinear T, (2008) Mycolactones: immunosuppressive and cytotoxic polyketides produced by aquatic mycobacteria. Nat Prod Rep 25: 447-454.
-
(2008)
Nat Prod Rep
, vol.25
, pp. 447-454
-
-
Hong, H.1
Demangel, C.2
Pidot, S.J.3
Leadlay, P.F.4
Stinear, T.5
-
14
-
-
0345393085
-
Identification using LC-MSn of co-metabolites in the biosynthesis of the polyketide toxin mycolactone by a clinical isolate of Mycobacterium ulcerans
-
Hong H, Gates PJ, Staunton J, Stinear T, Cole ST, et al. (2003) Identification using LC-MSn of co-metabolites in the biosynthesis of the polyketide toxin mycolactone by a clinical isolate of Mycobacterium ulcerans. Chem Commun (Camb) pp. 2822-2823.
-
(2003)
Chem Commun (Camb)
, pp. 2822-2823
-
-
Hong, H.1
Gates, P.J.2
Staunton, J.3
Stinear, T.4
Cole, S.T.5
-
15
-
-
21044436769
-
A novel mycolactone from a clinical isolate of Mycobacterium ulcerans provides evidence for additional toxin heterogeneity as a result of specific changes in the modular polyketide synthase
-
Hong H, Spencer JB, Porter JL, Leadlay PF, Stinear T, (2005) A novel mycolactone from a clinical isolate of Mycobacterium ulcerans provides evidence for additional toxin heterogeneity as a result of specific changes in the modular polyketide synthase. Chembiochem 6: 643-648.
-
(2005)
Chembiochem
, vol.6
, pp. 643-648
-
-
Hong, H.1
Spencer, J.B.2
Porter, J.L.3
Leadlay, P.F.4
Stinear, T.5
-
16
-
-
79955563075
-
Chemistry of mycolactones, the causative toxins of Buruli ulcer
-
Kishi Y, (2011) Chemistry of mycolactones, the causative toxins of Buruli ulcer. Proc Natl Acad Sci U S A 108: 6703-6708.
-
(2011)
Proc Natl Acad Sci U S A
, vol.108
, pp. 6703-6708
-
-
Kishi, Y.1
-
17
-
-
76949083226
-
Highly sensitive, operationally simple, cost/time effective detection of the mycolactones from the human pathogen Mycobacterium ulcerans
-
Spangenberg T, Kishi Y, (2010) Highly sensitive, operationally simple, cost/time effective detection of the mycolactones from the human pathogen Mycobacterium ulcerans. Chemical Communications 46: 1410-1412.
-
(2010)
Chemical Communications
, vol.46
, pp. 1410-1412
-
-
Spangenberg, T.1
Kishi, Y.2
-
18
-
-
57649174709
-
Buruli ulcer: Reductive evolution enhances pathogenicity of Mycobacterium ulcerans
-
Demangel C, Stinear TP, Cole ST, (2009) Buruli ulcer: Reductive evolution enhances pathogenicity of Mycobacterium ulcerans. Nat Rev Microbiol 7: 50-60.
-
(2009)
Nat Rev Microbiol
, vol.7
, pp. 50-60
-
-
Demangel, C.1
Stinear, T.P.2
Cole, S.T.3
-
19
-
-
0037149026
-
Total synthesis of the mycolactones
-
Song F, Fidanze S, Benowitz AB, Kishi Y, (2002) Total synthesis of the mycolactones. Org Lett 4: 647-650.
-
(2002)
Org Lett
, vol.4
, pp. 647-650
-
-
Song, F.1
Fidanze, S.2
Benowitz, A.B.3
Kishi, Y.4
-
20
-
-
34248631378
-
Total Synthesis of Mycolactones A and B
-
Song F, Fidanze S, Benowitz AB, Kishi Y, (2007) Total Synthesis of Mycolactones A and B. Tetrahedron 63: 5739-5753.
-
(2007)
Tetrahedron
, vol.63
, pp. 5739-5753
-
-
Song, F.1
Fidanze, S.2
Benowitz, A.B.3
Kishi, Y.4
-
21
-
-
84857676432
-
Local and Regional Re-Establishment of Cellular Immunity during Curative Antibiotherapy of Murine Mycobacterium ulcerans Infection
-
Martins TG, Gama JB, Fraga AG, Saraiva M, Silva MT, et al. (2012) Local and Regional Re-Establishment of Cellular Immunity during Curative Antibiotherapy of Murine Mycobacterium ulcerans Infection. PLoS ONE 7: e32740.
-
(2012)
PLoS ONE
, vol.7
-
-
Martins, T.G.1
Gama, J.B.2
Fraga, A.G.3
Saraiva, M.4
Silva, M.T.5
-
22
-
-
25444518934
-
Infection with Mycobacterium ulcerans Induces Persistent Inflammatory Responses in Mice
-
Oliveira MS, Fraga AG, Torrado E, Castro AG, Pereira JP, et al. (2005) Infection with Mycobacterium ulcerans Induces Persistent Inflammatory Responses in Mice. Infect Immun 73: 6299-6310.
-
(2005)
Infect Immun
, vol.73
, pp. 6299-6310
-
-
Oliveira, M.S.1
Fraga, A.G.2
Torrado, E.3
Castro, A.G.4
Pereira, J.P.5
-
23
-
-
84856072893
-
Chemotherapy-associated changes of histopathological features of Mycobacterium ulcerans lesions in a Buruli ulcer mouse model
-
Ruf MT, Schutte D, Chauffour A, Jarlier V, Ji B, et al. (2012) Chemotherapy-associated changes of histopathological features of Mycobacterium ulcerans lesions in a Buruli ulcer mouse model. Antimicrob Agents Chemother 56: 687-696.
-
(2012)
Antimicrob Agents Chemother
, vol.56
, pp. 687-696
-
-
Ruf, M.T.1
Schutte, D.2
Chauffour, A.3
Jarlier, V.4
Ji, B.5
-
24
-
-
84875998264
-
Microbiological, Histological, Immunological, and Toxin Response to Antibiotic Treatment in the Mouse Model of Mycobacterium ulcerans Disease
-
Sarfo FS, Converse PJ, Almeida DV, Zhang J, Robinson C, et al. (2013) Microbiological, Histological, Immunological, and Toxin Response to Antibiotic Treatment in the Mouse Model of Mycobacterium ulcerans Disease. PLoS Negl Trop Dis 7: e2101.
-
(2013)
PLoS Negl Trop Dis
, vol.7
-
-
Sarfo, F.S.1
Converse, P.J.2
Almeida, D.V.3
Zhang, J.4
Robinson, C.5
-
25
-
-
34547624336
-
Mycolactone-mediated inhibition of tumor necrosis factor production by macrophages infected with Mycobacterium ulcerans has implications for the control of infection
-
Torrado E, Adusumilli S, Fraga AG, Small PLC, Castro AG, et al. (2007) Mycolactone-mediated inhibition of tumor necrosis factor production by macrophages infected with Mycobacterium ulcerans has implications for the control of infection. Infect Immun 75: 3979-3988.
-
(2007)
Infect Immun
, vol.75
, pp. 3979-3988
-
-
Torrado, E.1
Adusumilli, S.2
Fraga, A.G.3
Small, P.L.C.4
Castro, A.G.5
-
26
-
-
33846781153
-
Evidence for an intramacrophage growth phase of Mycobacterium ulcerans
-
Torrado E, Fraga AG, Castro AG, Stragier P, Meyers WM, et al. (2007) Evidence for an intramacrophage growth phase of Mycobacterium ulcerans. Infect Immun 75: 977-987.
-
(2007)
Infect Immun
, vol.75
, pp. 977-987
-
-
Torrado, E.1
Fraga, A.G.2
Castro, A.G.3
Stragier, P.4
Meyers, W.M.5
-
27
-
-
79851489099
-
Activities of Rifampin, Rifapentine and Clarithromycin Alone and in Combination against Mycobacterium ulcerans Disease in Mice
-
Almeida D, Converse PJ, Ahmad Z, Dooley KE, Nuermberger EL, et al. (2011) Activities of Rifampin, Rifapentine and Clarithromycin Alone and in Combination against Mycobacterium ulcerans Disease in Mice. PLoS Negl Trop Dis 5: e933.
-
(2011)
PLoS Negl Trop Dis
, vol.5
-
-
Almeida, D.1
Converse, P.J.2
Ahmad, Z.3
Dooley, K.E.4
Nuermberger, E.L.5
-
28
-
-
79951668215
-
Oral Treatment for Mycobacterium ulcerans Infection: Results From a Pilot Study in Benin
-
Chauty A, Ardant M-Fß, Marsollier L, Pluschke G, Landier J, et al. (2011) Oral Treatment for Mycobacterium ulcerans Infection: Results From a Pilot Study in Benin. Clinical Infectious Diseases 52: 94-96.
-
(2011)
Clinical Infectious Diseases
, vol.52
, pp. 94-96
-
-
Chauty, A.1
Ardant, M.-Fß.2
Marsollier, L.3
Pluschke, G.4
Landier, J.5
-
29
-
-
44449153473
-
Bactericidal and sterilizing activities of several orally administered combined regimens against Mycobacterium ulcerans in mice
-
Ji B, Chauffour A, Robert J, Jarlier V, (2008) Bactericidal and sterilizing activities of several orally administered combined regimens against Mycobacterium ulcerans in mice. Antimicrob Agents Chemother 52: 1912-1916.
-
(2008)
Antimicrob Agents Chemother
, vol.52
, pp. 1912-1916
-
-
Ji, B.1
Chauffour, A.2
Robert, J.3
Jarlier, V.4
-
30
-
-
0013901466
-
Mycobacterium ulcerans infection. Clinical and bacteriological study of the first cases recognized in South East Asia
-
Pettit JHS, Marchette NJ, Rees RJW, (1966) Mycobacterium ulcerans infection. Clinical and bacteriological study of the first cases recognized in South East Asia. British Journal of Dermatology 78: 187-197.
-
(1966)
British Journal of Dermatology
, vol.78
, pp. 187-197
-
-
Pettit, J.H.S.1
Marchette, N.J.2
Rees, R.J.W.3
-
32
-
-
78650673813
-
Using Bioluminescence To Monitor Treatment Response in Real Time in Mice with Mycobacterium ulcerans Infection
-
Zhang T, Li S-Y, Converse PJ, Almeida DV, Grosset JH, et al. (2011) Using Bioluminescence To Monitor Treatment Response in Real Time in Mice with Mycobacterium ulcerans Infection. Antimicrob Agents Chemother 55: 56-61.
-
(2011)
Antimicrob Agents Chemother
, vol.55
, pp. 56-61
-
-
Zhang, T.1
Li, S.-Y.2
Converse, P.J.3
Almeida, D.V.4
Grosset, J.H.5
-
34
-
-
84865985002
-
Detection of Viable Mycobacterium ulcerans in Clinical Samples by a Novel Combined 16S rRNA Reverse Transcriptase/IS2404 Real-Time qPCR Assay
-
Beissner M, Symank D, Phillips RO, Amoako YA, Awua-Boateng N-Y, et al. (2012) Detection of Viable Mycobacterium ulcerans in Clinical Samples by a Novel Combined 16S rRNA Reverse Transcriptase/IS2404 Real-Time qPCR Assay. PLoS Negl Trop Dis 6: e1756.
-
(2012)
PLoS Negl Trop Dis
, vol.6
-
-
Beissner, M.1
Symank, D.2
Phillips, R.O.3
Amoako, Y.A.4
Awua-Boateng, N.-Y.5
-
35
-
-
84874785123
-
Bactericidal activity does not predict sterilizing activity: the case of rifapentine in the murine model of Mycobacterium ulcerans disease
-
Almeida DV, Converse PJ, Li SY, Tyagi S, Nuermberger EL, et al. (2013) Bactericidal activity does not predict sterilizing activity: the case of rifapentine in the murine model of Mycobacterium ulcerans disease. PLoS Negl Trop Dis 7: e2085.
-
(2013)
PLoS Negl Trop Dis
, vol.7
-
-
Almeida, D.V.1
Converse, P.J.2
Li, S.Y.3
Tyagi, S.4
Nuermberger, E.L.5
|