Comparing the utility of homogeneous subtypes of cocaine use and related behaviors with DSM-IV cocaine dependence as traits for genetic association analysis

American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics

Volumn 165, Issue 2, 2014, Pages 148-156

  Bi, Jinbo ^a   Gelernter, Joel ^b,c   Sun, Jiangwen ^a   Kranzler, Henry R ^d,e  

^a University of Connecticut   (United States)

^b YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c VA CONNECTICUT HEALTHCARE SYSTEM   (United States)

^d UNIVERSITY OF PENNSYLVANIA   (United States)

^e Education and Clinical Center   (United States)

Author keywords

Candidate genes; Cocaine; Cocaine dependence; Subtyping, subtype analysis

Indexed keywords

ALCOHOL; BRAIN DERIVED NEUROTROPHIC FACTOR; CENTRAL STIMULANT AGENT; COCAINE; NICOTINE; OPIATE; SEDATIVE AGENT; TRANSCRIPTION FACTOR CLOCK;

ADULT; AFRICAN AMERICAN; AGORAPHOBIA; ALCOHOLISM; ANTISOCIAL PERSONALITY DISORDER; ARTICLE; CHROMOSOME 4; CLINICAL FEATURE; CLUSTER ANALYSIS; COCAINE DEPENDENCE; COCAINE USE AND RELATED BEHAVIOR; COMORBIDITY; CONTROLLED STUDY; DRUG DEPENDENCE; DRUG USE; DSM-IV; EDUCATIONAL STATUS; EUROPEAN AMERICAN; FEMALE; GENE LINKAGE DISEQUILIBRIUM; GENETIC ASSOCIATION; GENOTYPE; HERITABILITY; HUMAN; MAJOR CLINICAL STUDY; MAJOR DEPRESSION; MALE; MARRIAGE; MIDDLE AGED; OBSESSIVE COMPULSIVE DISORDER; ONSET AGE; OPIATE ADDICTION; PANIC; PATHOLOGICAL GAMBLING; PHENOTYPE; POSTTRAUMATIC STRESS DISORDER; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM; SOCIAL PHOBIA; TOBACCO DEPENDENCE;

CANDIDATE GENES; COCAINE; COCAINE DEPENDENCE; SUBTYPING, SUBTYPE ANALYSIS;

ADULT; CHROMOSOME MAPPING; COCAINE-RELATED DISORDERS; DIAGNOSTIC AND STATISTICAL MANUAL OF MENTAL DISORDERS; FEMALE; GENE FREQUENCY; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HUMANS; MALE; POLYMORPHISM, SINGLE NUCLEOTIDE; YOUNG ADULT;

EID: 84893797304     PISSN: 15524841     EISSN: 1552485X     Source Type: Journal    
DOI: 10.1002/ajmg.b.32216     Document Type: Article

References (40)

1. Abarca C, Albrecht U, Spanagel R. 2002. Cocaine sensitization and reward are under the influence of circadian genes and rhythm. Proc Natl Acad Sci USA 99(13):9026-9030.
2. Abdi H, Valentin D. 2007. Multiple correspondence analysis. In: Salkind N, editor. Encyclopedia of measurement and statistics. Thousand Oaks, CA: SAGE.
3. Almasy L, Blangero J. 1998. Multipoint quantitative-trait linkage analysis in general pedigrees. Am J Hum Genet 62(5):1198-1211.
4. American Psychiatric Association. 1994. Diagnostic and statistical manual of mental disorders: DSM-IV. Washington, DC: American Psychiatric Association.
5. Andretic R, Chaney S, Hirsh J. 1999. Requirement of circadian genes for cocaine sensitization in Drosophila. Science 285(5430):1066-1068.
6. Basu D, Ball SA, Feinn R, Gelernter J, Kranzler HR. 2004. Typologies of drug dependence: Comparative validity of a multivariate and four univariate models. Drug Alcohol Depend 73(3):289-300.
7. Callahan PM, Cunningham KA. 1995. Modulation of the discriminative stimulus properties of cocaine by 5-HT1B and 5-HT2C receptors. J Pharmacol Exp Ther 274(3):1414-1424.
8. Cami J, Farre M. 2003. Drug addiction. N Engl J Med 349(10):975-986.
9. Cardoso JMN, Barbosa A, Ismail F, Pombo S. 2006. NETER alcoholic typology (NAT). Alcohol Alcohol (Oxford, Oxfordshire) 41(2):133-139.
10. Chan G, Gelernter J, Oslin D, Farrer L, Kranzler HR. 2011. Empirically derived subtypes of opioid use and related behaviors. Addiction 106(6):1146-1154.
11. Frankel PS, Cunningham KA. 2004. m-Chlorophenylpiperazine (mCPP) modulates the discriminative stimulus effects of cocaine through actions at the 5-HT2C receptor. Behav Neurosci 118(1):157-162.
12. Gelernter J, Panhuysen C, Weiss R, Brady K, Hesselbrock V, Rounsaville B, Poling J, Wilcox M, Farrer L, Kranzler HR. 2005a. Genomewide linkage scan for cocaine dependence and related traits: Significant linkages for a cocaine-related trait and cocaine-induced paranoia. Am J Med Genet Part B 136B(1):45.
13. Gelernter J, Panhuysen C, Weiss R, Brady K, Hesselbrock V, Rounsaville B, Poling J, Wilcox M, Farrer L, Kranzler HR. 2005b. Genomewide linkage scan for cocaine dependence and related traits: Significant linkages for a cocaine-related trait and cocaine-induced paranoia. Am J Med Genet Part B 136B(1):45-52.
14. Gelernter J, Panhuysen C, Wilcox M, Hesselbrock V, Rounsaville B, Poling J, Weiss R, Sonne S, Zhao H, Farrer L, et al. 2006. Genomewide linkage scan for opioid dependence and related traits. Am J Hum Genet 78(5):759.
15. Herman AI, Balogh KN. 2012. Polymorphisms of the serotonin transporter and receptor genes: Susceptibility to substance abuse. Subst Abuse Rehabil 3(1):49-457.
16. Hodgkinson CA, Yuan Q, Xu K, Shen PH, Heinz E, Lobos EA, Binder EB, Cubells J, Ehlers CL, Gelernter J, et al. 2008. Addictions biology: Haplotype-based analysis for 130 candidate genes on a single array. Alcohol Alcohol 43(5):505-515.
17. Kendler KS, Prescott CA. 1998. Cocaine use, abuse and dependence in a population-based sample of female twins. Br J Psychiatry 173:345-350.
18. Kranzler HR, Wilcox M, Weiss RD, Brady K, Hesselbrock V, Rounsaville B, Farrer L, Gelernter J. 2008. The validity of cocaine dependence subtypes. Addict Behav 33(1):41-53.
19. Kuo P-H, Aggen SH, Prescott CA, Kendler KS, Neale MC. 2008. Using a factor mixture modeling approach in alcohol dependence in a general population sample. Drug Alcohol Depend 98(1):105-114.
20. LeRoux B, Rouanet H. 2009. Multiple correspondence analysis. Los Angeles, CA: Sage.
21. Malison RT, Kranzler HR, Yang B-Z, Gelernter J. 2006. Human clock, PER1 and PER2 polymorphisms: Lack of association with cocaine dependence susceptibility and cocaine-induced paranoia. Psychiatr Genet 16(6):245-249.
22. McClung CA, Sidiropoulou K, Vitaterna M, Takahashi JS, White FJ, Cooper DC, Nestler EJ. 2005. Regulation of dopaminergic transmission and cocaine reward by the Clock gene. Proc Natl Acad Sci USA 102(26):9377-9381.
23. Murtagh F. 2007. Multiple correspondence analysis and related methods. Psychometrika 72(2):275-277.
24. Perreau-Lenz S, Zghoul T, Spanagel R. 2007. Clock genes running amok. Clock genes and their role in drug addiction and depression. EMBO Rep 8:S20-S23.
25. Pierucci-Lagha A, Gelernter J, Feinn R, Cubells JF, Pearson D, Pollastri A, Farrer L, Kranzler HR. 2005. Diagnostic reliability of the semi-structured assessment for drug dependence and alcoholism (SSADDA). Drug Alcohol Depend 80(3):303-312.
26. Pierucci-Lagha A, Gelernter J, Chan G, Arias A, Cubells JF, Farrer L, Kranzler HR. 2007. Reliability of DSM-IV diagnostic criteria using the semi-structured assessment for drug dependence and alcoholism (SSADDA). Drug Alcohol Depend 91(1):85-90.
27. Pritchard JK, Stephens M, Donnelly P. 2000. Inference of population structure using multilocus genotype data. Genetics 155(2):945-959.
28. Purcell S. 2009. Package: PLINK v1.07. http://pngumghharvardedu/purcell/plink
29. Purcell S, Neale B, Todd-Brown K, Thomas L, Ferreira M, Bender D, Maller J, Sklar P, de Bakker P, Daly MJ, et al. 2007. PLINK: A toolset for whole-genome association and population-based linkage analysis. Am J Hum Genet 81(3):559-575.
30. Roncero C, Ros-Cucurull E, Daigre C, Casas M. 2012. Prevalence and risk factors of psychotic symptoms in cocaine-dependent patients. Actas Esp Psiquiatr 40(4):187-197.
31. SAS Institute, Inc. 2008. SAS(r) 9.2 enhanced logging facilities. Cary, NC: SAS Institute, Inc.
32. Saxon AJ, Oreskovich MR, Brkanac Z. 2005. Genetic determinants of addiction to opioids and cocaine. Harv Rev Psychiatry 13(4):218-232.
33. Spanagel R, Weiss F. 1999. The dopamine hypothesis of reward: Past and current status. Trends Neurosci 22(11):521-527.
34. Substance Abuse and Mental Health Services Administration. 2011. Results from the 2010 National Survey on Drug Use and Health: Summary of National Findings. NSDUH Series H-41, HHS Publication No (SMA) 11-4658. Rockville, MD: Substance Abuse and Mental Health Services Administration.
35. Sun J, Bi J, Chan G, Oslin D, Farrer L, Gelernter J, Kranzler HR. 2012. Improved methods to identify stable, highly heritable subtypes of opioid use and related behaviors. Addict Behav 37(10):1138-1144.
36. Tsuang MT, Lyons MJ, Eisen SA, Goldberg J, True W, Lin N, Meyer JM, Toomey R, Faraone SV, Eaves L. 1996. Genetic influences on DSM-III-R drug abuse and dependence: A study of 3, 372 twin pairs. American Journal of Medical Genetics Part B, Neuropsychiatr Genet 67(5):473-477.
37. Tsuang MT, Lyons MJ, Meyer JM, Doyle T, Eisen SA, Goldberg J, True W, Lin N, Toomey R, Eaves L. 1998. Co-occurrence of abuse of different drugs in men: The role of drug-specific and shared vulnerabilities. Arch Gen Psychiatry 55(11):967-972.
38. Uhl GR, Elmer GI, LaBuda MC, Pickens RW. 1995. Genetic influences in drug abuse. New York: Raven Press.
39. Wan X, Yang C, Yang Q, Xue H, Fan X, Tang NL, Yu W. 2010. BOOST: A fast approach to detecting gene-gene interactions in genome-wide case-control studies. Am J Hum Genet 87(3):325-340.
40. Yuferov V, Butelman ER, Kreek MJ. 2005. Biological clock: Biological clocks may modulate drug addiction. Eur J Hum Genet 13(10):1101-1103.